NO20012965L - Sulfonyloksazolaminer som terapeutisk aktive forbindelser - Google Patents
Sulfonyloksazolaminer som terapeutisk aktive forbindelserInfo
- Publication number
- NO20012965L NO20012965L NO20012965A NO20012965A NO20012965L NO 20012965 L NO20012965 L NO 20012965L NO 20012965 A NO20012965 A NO 20012965A NO 20012965 A NO20012965 A NO 20012965A NO 20012965 L NO20012965 L NO 20012965L
- Authority
- NO
- Norway
- Prior art keywords
- active compounds
- therapeutically active
- atoms
- sulfonyloxazolamines
- preparation
- Prior art date
Links
- HVISAPYMDYXBIV-UHFFFAOYSA-N 2-(sulfonylamino)-1,3-oxazole Chemical class O=S(=O)=NC1=NC=CO1 HVISAPYMDYXBIV-UHFFFAOYSA-N 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Foreliggende oppfinnelse vedrører sulfonyl- oksazolaminer med den generelle formel (I) hvor R1, R2 uavhengig av hverandre betyr H, A, -(CH2)n-Ar eller alkenyl med 2 til 6 C-atomer, R1 og R2 til sammen også kan bety en enkjernet, mettet heterosyklisk ring med 1-2 N-, O- og/eller S- atomer, Z betyr H, A, CF3, NO2, Hal, OH, OA, NH2, NHA eller NA2) A betyr alkyl med 1-6 C-atomer, Ar betyr fenyl som er mono- eller disubstituert med Z, Hal betyr F, Cl, Br eller I, og n betyr l eller 2, eller deres fysiologisk akseptable salter eller solvater som terapeutisk aktive forbindelser, anvendelsen av sulfonyloksazolaminene som terapeutisk aktive for- bindelser, og/eller til fremstilling av farmasøytiske preparater ved bekjempelsen av sykdommer i sentral- nervesystemet, et farmasøytisk preparat og fremstil- lingen av dette.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19858593A DE19858593A1 (de) | 1998-12-18 | 1998-12-18 | Sulfonyloxazolamine als therapeutische Wirkstoffe |
| PCT/EP1999/009335 WO2000037452A1 (de) | 1998-12-18 | 1999-12-01 | Sulfonyloxazolamine als therapeutische wirkstoffe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20012965D0 NO20012965D0 (no) | 2001-06-15 |
| NO20012965L true NO20012965L (no) | 2001-06-15 |
Family
ID=7891645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20012965A NO20012965L (no) | 1998-12-18 | 2001-06-15 | Sulfonyloksazolaminer som terapeutisk aktive forbindelser |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6441013B1 (no) |
| EP (1) | EP1140875A1 (no) |
| JP (1) | JP2002533332A (no) |
| CN (1) | CN1146549C (no) |
| AR (1) | AR021896A1 (no) |
| AU (1) | AU763070B2 (no) |
| BR (1) | BR9916310A (no) |
| CA (1) | CA2356134A1 (no) |
| CZ (1) | CZ20012144A3 (no) |
| DE (1) | DE19858593A1 (no) |
| HK (1) | HK1043125A1 (no) |
| HU (1) | HUP0104834A3 (no) |
| ID (1) | ID29966A (no) |
| NO (1) | NO20012965L (no) |
| PL (1) | PL349393A1 (no) |
| RU (1) | RU2232757C2 (no) |
| SK (1) | SK8132001A3 (no) |
| WO (1) | WO2000037452A1 (no) |
| ZA (1) | ZA200105881B (no) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19956791A1 (de) * | 1999-11-25 | 2001-05-31 | Merck Patent Gmbh | Neue Sulfonyloxazolamine |
| DE10129940A1 (de) * | 2001-06-13 | 2002-12-19 | Merck Patent Gmbh | Sulfonyloxazolamine als therapeutische Wirkstoffe |
| US6875771B2 (en) | 2002-07-26 | 2005-04-05 | Bristol-Myers Squibb Company | Pyridopyrimidine derivatives as 5-HT6 antagonists |
| FR2854632B1 (fr) * | 2003-05-07 | 2005-06-17 | Centre Nat Rech Scient | Synthese de composes heterocycliques substitues |
| GB0419192D0 (en) * | 2004-08-27 | 2004-09-29 | Merck Sharp & Dohme | Therapeutic agents |
| CN101119965B (zh) * | 2004-12-21 | 2012-09-26 | 弗·哈夫曼-拉罗切有限公司 | 萘满和茚满衍生物及其用途 |
| WO2007016979A2 (en) * | 2005-07-29 | 2007-02-15 | 4Sc Ag | NOVEL HETEROCYCLIC NF-κB INHIBITORS |
| DE102005061429A1 (de) * | 2005-12-22 | 2007-06-28 | Grünenthal GmbH | Substituierte Oxazol-Derivate |
| WO2008061248A2 (en) * | 2006-11-16 | 2008-05-22 | The Regents Of The University Of California | Phenylsulfoxyoxazole compound inhibitors of urea transporters |
| CA2675221C (en) * | 2007-02-02 | 2016-02-23 | F. Hoffmann-La Roche Ag | Novel 2-aminooxazolines as taar1 ligands |
| MX2009008465A (es) * | 2007-02-15 | 2009-08-20 | Hoffmann La Roche | Nuevas 2-aminooxazolinas como ligandos de taar1. |
| WO2011080840A1 (ja) | 2009-12-28 | 2011-07-07 | ブラザー工業株式会社 | テープカセット |
| RU2443697C1 (ru) | 2010-12-21 | 2012-02-27 | Александр Васильевич Иващенко | Замещенные метил-амины, антагонисты серотониновых 5-ht6 рецепторов, способы получения и применения |
| WO2018012769A1 (ko) * | 2016-07-12 | 2018-01-18 | 연세대학교 산학협력단 | 자가포식 향상물질 및 그 용도 |
| KR102533605B1 (ko) * | 2018-01-10 | 2023-05-17 | 주식회사 라이조테크 | 신규한 페닐설포닐 옥사졸 유도체 및 이의 용도 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11509835A (ja) * | 1995-05-19 | 1999-08-31 | ジー．ディー．サール アンド カンパニー | 炎症を治療するための置換オキサゾール |
| AU717230B2 (en) * | 1996-02-20 | 2000-03-23 | Bristol-Myers Squibb Company | Methods for the preparation of biphenyl isoxazole sulfonamides |
-
1998
- 1998-12-18 DE DE19858593A patent/DE19858593A1/de not_active Withdrawn
-
1999
- 1999-12-01 WO PCT/EP1999/009335 patent/WO2000037452A1/de not_active Ceased
- 1999-12-01 US US09/868,097 patent/US6441013B1/en not_active Expired - Fee Related
- 1999-12-01 ID IDW00200101555A patent/ID29966A/id unknown
- 1999-12-01 CZ CZ20012144A patent/CZ20012144A3/cs unknown
- 1999-12-01 CN CNB998147281A patent/CN1146549C/zh not_active Expired - Fee Related
- 1999-12-01 PL PL99349393A patent/PL349393A1/xx unknown
- 1999-12-01 HK HK02104944.7A patent/HK1043125A1/zh unknown
- 1999-12-01 CA CA002356134A patent/CA2356134A1/en not_active Abandoned
- 1999-12-01 EP EP99962190A patent/EP1140875A1/de not_active Withdrawn
- 1999-12-01 JP JP2000589524A patent/JP2002533332A/ja active Pending
- 1999-12-01 BR BR9916310-1A patent/BR9916310A/pt not_active IP Right Cessation
- 1999-12-01 SK SK813-2001A patent/SK8132001A3/sk unknown
- 1999-12-01 HU HU0104834A patent/HUP0104834A3/hu unknown
- 1999-12-01 AU AU18612/00A patent/AU763070B2/en not_active Ceased
- 1999-12-01 RU RU2001119273/04A patent/RU2232757C2/ru not_active IP Right Cessation
- 1999-12-17 AR ARP990106528A patent/AR021896A1/es not_active Application Discontinuation
-
2001
- 2001-06-15 NO NO20012965A patent/NO20012965L/no not_active Application Discontinuation
- 2001-07-17 ZA ZA200105881A patent/ZA200105881B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK8132001A3 (en) | 2002-02-05 |
| HUP0104834A2 (hu) | 2002-07-29 |
| DE19858593A1 (de) | 2000-06-21 |
| HK1043125A1 (zh) | 2002-09-06 |
| CN1331684A (zh) | 2002-01-16 |
| ID29966A (id) | 2001-10-25 |
| BR9916310A (pt) | 2001-11-06 |
| JP2002533332A (ja) | 2002-10-08 |
| NO20012965D0 (no) | 2001-06-15 |
| AR021896A1 (es) | 2002-08-07 |
| HUP0104834A3 (en) | 2005-06-28 |
| ZA200105881B (en) | 2002-10-17 |
| EP1140875A1 (de) | 2001-10-10 |
| US6441013B1 (en) | 2002-08-27 |
| AU1861200A (en) | 2000-07-12 |
| AU763070B2 (en) | 2003-07-10 |
| CA2356134A1 (en) | 2000-06-29 |
| WO2000037452A1 (de) | 2000-06-29 |
| PL349393A1 (en) | 2002-07-15 |
| RU2232757C2 (ru) | 2004-07-20 |
| CZ20012144A3 (cs) | 2002-01-16 |
| CN1146549C (zh) | 2004-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |