NO20013085L - Fosfororganiske forbindelser og deres anvendelse - Google Patents

Fosfororganiske forbindelser og deres anvendelse

Info

Publication number
NO20013085L
NO20013085L NO20013085A NO20013085A NO20013085L NO 20013085 L NO20013085 L NO 20013085L NO 20013085 A NO20013085 A NO 20013085A NO 20013085 A NO20013085 A NO 20013085A NO 20013085 L NO20013085 L NO 20013085L
Authority
NO
Norway
Prior art keywords
group
bio
substituents
hydroxamic acid
phosphorus
Prior art date
Application number
NO20013085A
Other languages
English (en)
Other versions
NO20013085D0 (no
Inventor
Hassan Jomaa
Original Assignee
Jomaa Pharmaka Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jomaa Pharmaka Gmbh filed Critical Jomaa Pharmaka Gmbh
Publication of NO20013085D0 publication Critical patent/NO20013085D0/no
Publication of NO20013085L publication Critical patent/NO20013085L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/62—Isoquinoline or hydrogenated isoquinoline ring systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/24—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing heterocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5537—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Fosfororganiske forbindelser med den generelle formel (I), o II P- R< (D hvor A er valgt blant Ci-9-alkylen- grupper, -C-O-C- og -C-N-C-, eller A har svarer til formel (II), 1' f7 ?' (IQ B2 B« Be Ba Bio hvor ett eller flere karbonatomer valgt fra gruppen bestående av C3, C4, Cs også kan være fraværende sammen med sine substituenter, og minst en av substitu- entene fra BI til BIO er en C3.e-syklo- alkyl-(Co-g)-alkylgruppe, samt hvor RI er valgt blant S- og 6-leddede heterosyk- luser med minst ett nitrogenatom i ringen eller polysykliske hydrokarbon- forbindelser inneholdende minst en av disse heterosykluser, idet minst ett av disse nitrogenatomer hører til en hydroksaminsyregruppe eller en hydroks- aminsyreestergruppe. Forbindelsene er anvendbare for terapeutisk og forebyg- gende behandling av infeksjoner hos mennesker og dyr som forårsakes av virus, bakterier, fungi og parasitter, og som fungicider, baktericider og herbicider overfor planter.
NO20013085A 1998-12-22 2001-06-21 Fosfororganiske forbindelser og deres anvendelse NO20013085L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19859426A DE19859426A1 (de) 1998-12-22 1998-12-22 Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen
PCT/EP1999/010274 WO2000037477A1 (de) 1998-12-22 1999-12-22 Phosphororganische verbindungen und ihre verwendung

Publications (2)

Publication Number Publication Date
NO20013085D0 NO20013085D0 (no) 2001-06-21
NO20013085L true NO20013085L (no) 2001-08-22

Family

ID=7892237

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013085A NO20013085L (no) 1998-12-22 2001-06-21 Fosfororganiske forbindelser og deres anvendelse

Country Status (25)

Country Link
EP (1) EP1140952B1 (no)
JP (1) JP2002533350A (no)
KR (1) KR20010089670A (no)
CN (1) CN1331695A (no)
AP (1) AP2001002168A0 (no)
AT (1) ATE248846T1 (no)
AU (1) AU2538500A (no)
BR (1) BR9916466A (no)
CA (1) CA2356289A1 (no)
CZ (1) CZ20012284A3 (no)
DE (2) DE19859426A1 (no)
DK (1) DK1140952T3 (no)
EA (1) EA200100689A1 (no)
ES (1) ES2204189T3 (no)
HU (1) HUP0104866A3 (no)
IL (1) IL143470A0 (no)
MX (1) MXPA01006456A (no)
NO (1) NO20013085L (no)
OA (1) OA11730A (no)
PL (1) PL349045A1 (no)
PT (1) PT1140952E (no)
SK (1) SK8892001A3 (no)
TR (1) TR200101832T2 (no)
WO (1) WO2000037477A1 (no)
ZA (1) ZA200104443B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002078714A1 (de) * 2001-03-30 2002-10-10 Jomaa Pharmaka Gmbh Magensaftresistente formulierungen zur applikation von antiinfektiös wirkenden verbindungen, die den 2-c-methylerythrose-4-stoffwechselweg hemmen, sowie ihren salzen und estern
AU2007304839A1 (en) * 2006-10-06 2008-04-10 Unilever Plc Furanone compounds and lactam analogues thereof
EP2018864A1 (en) 2007-07-23 2009-01-28 Biomet Deutschland GmbH Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
CN101977610B (zh) 2008-01-25 2012-05-16 奇默里克斯公司 治疗病毒感染的方法
PT2534150T (pt) 2010-02-12 2017-05-02 Chimerix Inc Métodos para tratar uma infecção viral
US9278135B2 (en) 2010-04-26 2016-03-08 Chimerix Inc. Methods of treating retroviral infections and related dosage regimes
JP2017529393A (ja) 2014-09-12 2017-10-05 アンティバイオティクス エーピーエスAntibiotx Aps ハロゲン化サリチルアニリドの抗菌用途
WO2016145113A1 (en) * 2015-03-09 2016-09-15 Board Of Regents, The University Of Texas System Enolase inhibitors and methods of treatment therewith
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
GB201604484D0 (en) 2016-03-16 2016-04-27 Antibiotx Aps And Københavns Uni University Of Copenhagen Topical antibacterial compositions
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206156A (en) * 1976-07-27 1980-06-03 Fujisawa Pharmaceutical Company, Limited Hydroxyaminohydrocarbonphosphonic acids
US4693742A (en) * 1983-12-20 1987-09-15 Rohm And Hass Company Herbicidal hydroxyamino phosphonic acids and derivatives
JPS61106504A (ja) * 1984-10-30 1986-05-24 Teijin Ltd 除草剤
BR9909668A (pt) * 1998-04-14 2000-12-19 Jomaa Hassan Uso de compostos de organofósforo para o tratamento terapêutico e profilático de infecções

Also Published As

Publication number Publication date
JP2002533350A (ja) 2002-10-08
ES2204189T3 (es) 2004-04-16
IL143470A0 (en) 2002-04-21
EP1140952B1 (de) 2003-09-03
OA11730A (en) 2005-05-12
KR20010089670A (ko) 2001-10-08
SK8892001A3 (en) 2001-12-03
NO20013085D0 (no) 2001-06-21
CZ20012284A3 (cs) 2001-10-17
AU2538500A (en) 2000-07-12
CN1331695A (zh) 2002-01-16
MXPA01006456A (es) 2002-04-24
ATE248846T1 (de) 2003-09-15
DE59906907D1 (de) 2003-10-09
CA2356289A1 (en) 2000-06-29
HUP0104866A3 (en) 2002-08-28
PT1140952E (pt) 2004-02-27
AP2001002168A0 (en) 2001-06-30
TR200101832T2 (tr) 2001-12-21
DK1140952T3 (da) 2004-01-12
WO2000037477A1 (de) 2000-06-29
EA200100689A1 (ru) 2001-12-24
EP1140952A1 (de) 2001-10-10
HUP0104866A2 (en) 2002-06-29
DE19859426A1 (de) 2000-07-06
PL349045A1 (en) 2002-07-01
ZA200104443B (en) 2002-01-14
BR9916466A (pt) 2001-09-25

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