NO20013384L - Imidazo[4,5-c]pyridin-4-on-derivater - Google Patents

Imidazo[4,5-c]pyridin-4-on-derivater

Info

Publication number
NO20013384L
NO20013384L NO20013384A NO20013384A NO20013384L NO 20013384 L NO20013384 L NO 20013384L NO 20013384 A NO20013384 A NO 20013384A NO 20013384 A NO20013384 A NO 20013384A NO 20013384 L NO20013384 L NO 20013384L
Authority
NO
Norway
Prior art keywords
imidazo
pyridine
derivatives
prophylaxis
inhibitors
Prior art date
Application number
NO20013384A
Other languages
English (en)
Other versions
NO20013384D0 (no
Inventor
Werner Mederski
Horst Juraszyk
Hanns Wurziger
Christos Tsaklakidis
Dieter Dorsch
Sabine Bernotat-Danielowski
Guido Melzer
Soheila Anzali
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20013384D0 publication Critical patent/NO20013384D0/no
Publication of NO20013384L publication Critical patent/NO20013384L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nye forbindelser med formel (I) hvor R, R1, R2, RJ og n har de i krav l angitte betydninger, er inhibitorer for koagulasjonsfaktor Xa og kan anven- des til profylakse og/eller behandling av tromboemboliske sykdommer.
NO20013384A 1999-01-08 2001-07-06 Imidazo[4,5-c]pyridin-4-on-derivater NO20013384L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19900471A DE19900471A1 (de) 1999-01-08 1999-01-08 Imidazo[4,5c]-pyridin-4-on-derivate
PCT/EP1999/010236 WO2000040583A2 (de) 1999-01-08 1999-12-21 Imidazo[4,5-c]-pyridin-4-on-derivate

Publications (2)

Publication Number Publication Date
NO20013384D0 NO20013384D0 (no) 2001-07-06
NO20013384L true NO20013384L (no) 2001-07-06

Family

ID=7893790

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013384A NO20013384L (no) 1999-01-08 2001-07-06 Imidazo[4,5-c]pyridin-4-on-derivater

Country Status (16)

Country Link
EP (1) EP1149099A2 (no)
JP (1) JP2002534429A (no)
KR (1) KR20010086085A (no)
CN (1) CN1333772A (no)
AR (1) AR022220A1 (no)
AU (1) AU3041700A (no)
BR (1) BR9916774A (no)
CA (1) CA2357771A1 (no)
CZ (1) CZ20012407A3 (no)
DE (1) DE19900471A1 (no)
HU (1) HUP0105054A3 (no)
NO (1) NO20013384L (no)
PL (1) PL349341A1 (no)
SK (1) SK9442001A3 (no)
WO (1) WO2000040583A2 (no)
ZA (1) ZA200106454B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69921358T2 (de) 1998-12-23 2006-03-09 Bristol-Myers Squibb Pharma Co. Stickstoffhaltige heterobicyclen als faktor-xa-hemmer
EP1296982B1 (en) 2000-06-23 2007-09-19 Bristol-Myers Squibb Pharma Company 1-(heteroaryl-phenyl)-condensed pyrazol derivatives as factor xa inhibitors
EP1414449A4 (en) 2001-05-22 2005-04-06 Bristol Myers Squibb Co FACTOR XA BICYCLIC INHIBITORS
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
GB0225399D0 (en) * 2002-10-31 2002-12-11 Merck Sharp & Dohme Therapeutic agents
AU2003302238A1 (en) 2002-12-03 2004-06-23 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
US7550590B2 (en) 2003-03-25 2009-06-23 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2004103993A1 (en) 2003-05-14 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
KR20060041309A (ko) 2003-08-13 2006-05-11 다케다 야쿠힌 고교 가부시키가이샤 ４-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
NZ595000A (en) 2003-12-22 2013-03-28 Gilead Sciences Inc Imidazo[4,5-c]pyridine derivative for treating viral infections
NZ556624A (en) 2004-12-21 2010-06-25 Gilead Sciences Inc 5-((3-(2,4-trifluoromethyphenyl)isoxazol-5-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine and method of antiviral treatment
CN101223167B (zh) * 2005-07-15 2011-08-31 弗·哈夫曼-拉罗切有限公司 杂芳基稠合的环状胺
GEP20135838B (en) 2005-09-14 2013-06-10 Takeda Pharmaceutical Dipeptidyl peptidase inhibitors usage at diabetes treatment
CN101360723A (zh) 2005-09-16 2009-02-04 武田药品工业株式会社 制备嘧啶二酮衍生物的方法
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
DE602007004220D1 (de) 2006-07-07 2010-02-25 Leuven K U Res & Dev Neue pyridazinverbindung und ihre verwendung
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
US10005775B2 (en) * 2014-08-12 2018-06-26 Syngenta Participations, Ag Pesticidally active heterocyclic derivatives with sulphur containing substituents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW219935B (no) * 1991-12-25 1994-02-01 Mitsubishi Chemicals Co Ltd
JP2001524522A (ja) * 1997-12-01 2001-12-04 メルク エンド カムパニー インコーポレーテッド トロンビン阻害剤

Also Published As

Publication number Publication date
AR022220A1 (es) 2002-09-04
KR20010086085A (ko) 2001-09-07
EP1149099A2 (de) 2001-10-31
PL349341A1 (en) 2002-07-15
AU3041700A (en) 2000-07-24
BR9916774A (pt) 2001-10-30
WO2000040583A2 (de) 2000-07-13
NO20013384D0 (no) 2001-07-06
SK9442001A3 (en) 2002-05-09
HUP0105054A2 (hu) 2002-05-29
DE19900471A1 (de) 2000-07-13
HUP0105054A3 (en) 2002-12-28
ZA200106454B (en) 2002-11-06
WO2000040583A3 (de) 2000-09-21
CA2357771A1 (en) 2000-07-13
CZ20012407A3 (cs) 2001-12-12
CN1333772A (zh) 2002-01-30
JP2002534429A (ja) 2002-10-15

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application