NO20014363L - 4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler - Google Patents

4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler

Info

Publication number
NO20014363L
NO20014363L NO20014363A NO20014363A NO20014363L NO 20014363 L NO20014363 L NO 20014363L NO 20014363 A NO20014363 A NO 20014363A NO 20014363 A NO20014363 A NO 20014363A NO 20014363 L NO20014363 L NO 20014363L
Authority
NO
Norway
Prior art keywords
antivirals
carboxamides
thieno
dihydro
oxo
Prior art date
Application number
NO20014363A
Other languages
English (en)
Norwegian (no)
Other versions
NO20014363D0 (no
Inventor
Mark E Schnute
Michele M Cudahy
Allen Scott
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO20014363D0 publication Critical patent/NO20014363D0/no
Publication of NO20014363L publication Critical patent/NO20014363L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
NO20014363A 1999-03-09 2001-09-07 4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler NO20014363L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12366099P 1999-03-09 1999-03-09
PCT/US2000/005937 WO2000053610A2 (fr) 1999-03-09 2000-03-07 AGENTS ANTIVIRAUX DE 4-OXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES

Publications (2)

Publication Number Publication Date
NO20014363D0 NO20014363D0 (no) 2001-09-07
NO20014363L true NO20014363L (no) 2001-11-08

Family

ID=22410054

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014363A NO20014363L (no) 1999-03-09 2001-09-07 4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler

Country Status (25)

Country Link
US (2) US6239142B1 (fr)
EP (1) EP1159279B1 (fr)
JP (1) JP2002539130A (fr)
KR (1) KR20010102543A (fr)
CN (1) CN1347417A (fr)
AT (1) ATE226208T1 (fr)
AU (1) AU759875B2 (fr)
BR (1) BR0008804A (fr)
CA (1) CA2366609A1 (fr)
CZ (1) CZ20013028A3 (fr)
DE (1) DE60000611T2 (fr)
DK (1) DK1159279T3 (fr)
EA (1) EA003607B1 (fr)
ES (1) ES2184705T3 (fr)
HK (1) HK1045518A1 (fr)
HU (1) HUP0200324A3 (fr)
IL (1) IL145005A0 (fr)
NO (1) NO20014363L (fr)
NZ (1) NZ513758A (fr)
PL (1) PL350651A1 (fr)
PT (1) PT1159279E (fr)
SK (1) SK12582001A3 (fr)
TW (1) TWI222451B (fr)
WO (1) WO2000053610A2 (fr)
ZA (1) ZA200107255B (fr)

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US6730682B2 (en) 2000-07-12 2004-05-04 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6562822B2 (en) 2000-07-12 2003-05-13 Pharmacia & Upjohn Company Heterocyle carboxamides as antiviral agents
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US8101629B2 (en) 2001-08-13 2012-01-24 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
US7638522B2 (en) 2001-08-13 2009-12-29 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
JO3429B1 (ar) 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
WO2003020729A1 (fr) * 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxamides en tant qu'agents antiviraux
WO2003020728A1 (fr) * 2001-08-30 2003-03-13 Pharmacia & Upjohn Company Agents antiviraux a base de 4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides
WO2003053944A1 (fr) * 2001-12-20 2003-07-03 Osi Pharmaceuticals, Inc. Composes inhibiteurs de la lipase pancreatique, leur synthese et leur utilisation
AR038118A1 (es) * 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
AR038294A1 (es) 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
AR038117A1 (es) * 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
WO2003089437A1 (fr) * 2002-04-22 2003-10-30 Pharmacia & Upjohn Company Procede a l'acide trifluoroacetique permettant de preparer des intermediaires [2,3-b]pyridine
US7399856B2 (en) 2002-08-09 2008-07-15 Janssen Pharmaceutica N.V. Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-2pyrimidinyl]amino]benzonitrile
AU2003262947A1 (en) * 2002-08-30 2004-03-19 Pharmacia And Upjohn Company Method of preventing or treating atherosclerosis or restenosis
US20040176366A1 (en) * 2002-08-30 2004-09-09 Wathen Michael W Method of preventing or treating atherosclerosis or restenosis
US20040102473A1 (en) * 2002-08-30 2004-05-27 Wathen Michael W. Method of preventing or treating atherosclerosis or restenosis
WO2004019940A1 (fr) * 2002-08-30 2004-03-11 Pharmacia & Upjohn Company Carboxamides heterocycliques destines au traitement de l'atherosclerose ou de la restenose
WO2004106345A2 (fr) * 2002-09-04 2004-12-09 Pharmacia & Upjohn Company Derives d'aryl-ethanolamine, agents antiviraux
AU2003269950A1 (en) * 2002-09-04 2004-03-29 Pharmacia & Upjohn Company Llc Heteroaryl-ethanolamine derivatives as antiviral agents
US6831081B2 (en) * 2002-09-04 2004-12-14 Pharmacia & Upjohn 4-Oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents
US20040116464A1 (en) * 2002-09-04 2004-06-17 Schnute Mark E. Aryl-ethanolamine derivatives as antiviral agents
WO2005003140A1 (fr) * 2003-07-02 2005-01-13 Pharmacia & Upjohn Company Llc 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides utilises comme agents antiviraux
WO2005100338A1 (fr) * 2004-04-13 2005-10-27 Astex Therapeutics Limited Composes pharmaceutiques de 5-morpholinylmethylthiophenyle utilises comme modulateurs de la p38 map kinase
SE0401578D0 (sv) 2004-06-18 2004-06-18 Active Biotech Ab Novel compounds
WO2006093518A2 (fr) * 2004-06-25 2006-09-08 Apath, Llc Composes thienyle pour traiter des etats pathologiques lies a un virus
WO2010099166A1 (fr) * 2009-02-27 2010-09-02 Siga Technologies, Inc. Dérivés de thiénopyridine pour le traitement et la prévention d'infections par le virus de la dengue
BR112018016689A2 (pt) 2016-02-16 2019-02-12 Univ Vanderbilt moduladores alostéricos positivos do receptor muscarínico de acetilcolina m1
US10899759B2 (en) 2016-09-30 2021-01-26 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M1
US11072610B2 (en) 2018-09-12 2021-07-27 Novartis Ag Antiviral pyridopyrazinedione compounds
CN114667285B (zh) 2019-09-26 2025-08-08 诺华股份有限公司 抗病毒吡唑并吡啶酮化合物
CN115073489B (zh) * 2021-03-15 2023-11-28 同济大学 一种噻吩骈吡啶酮类化合物、制备方法及一种抗真菌药物
WO2022221602A2 (fr) * 2021-04-14 2022-10-20 University Of Virginia Patent Foundation Composition et méthodes de traitement et/ou de prévention de lésions pulmonaires

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CA2036618C (fr) * 1990-02-22 2002-10-29 Akira Morimoto Derives thiophene a anneaux condenses, leur production et leur utilisation
WO1992003427A1 (fr) 1990-08-17 1992-03-05 Yoshitomi Pharmaceutical Industries, Ltd. Compose de cetone et remede pour l'osteoporose
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Also Published As

Publication number Publication date
EP1159279B1 (fr) 2002-10-16
US6239142B1 (en) 2001-05-29
US6495683B2 (en) 2002-12-17
TWI222451B (en) 2004-10-21
AU759875B2 (en) 2003-05-01
WO2000053610A2 (fr) 2000-09-14
NO20014363D0 (no) 2001-09-07
DE60000611T2 (de) 2003-06-26
SK12582001A3 (sk) 2002-02-05
ZA200107255B (en) 2002-12-02
JP2002539130A (ja) 2002-11-19
EA003607B1 (ru) 2003-06-26
IL145005A0 (en) 2002-06-30
CA2366609A1 (fr) 2000-09-14
PL350651A1 (en) 2003-01-27
HUP0200324A2 (en) 2002-06-29
PT1159279E (pt) 2003-02-28
CZ20013028A3 (cs) 2002-03-13
NZ513758A (en) 2001-09-28
HK1045518A1 (zh) 2002-11-29
ES2184705T3 (es) 2003-04-16
AU3516200A (en) 2000-09-28
WO2000053610A3 (fr) 2001-01-25
ATE226208T1 (de) 2002-11-15
DE60000611D1 (en) 2002-11-21
EP1159279A2 (fr) 2001-12-05
DK1159279T3 (da) 2003-02-17
HUP0200324A3 (en) 2003-07-28
KR20010102543A (ko) 2001-11-15
CN1347417A (zh) 2002-05-01
BR0008804A (pt) 2002-04-16
EA200100955A1 (ru) 2002-02-28
US20020006937A1 (en) 2002-01-17

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application