NO20014603L - Tienopyrimidinforbindelser, deres fremstilling og anvendelse - Google Patents

Tienopyrimidinforbindelser, deres fremstilling og anvendelse

Info

Publication number: NO20014603L
Authority: NO; Norway
Prior art keywords: tienopyrimidine; compounds; preparation; tienopyrimidine compounds
Prior art date: 1999-03-24

Application number

NO20014603A

Other languages

English (en)

Norwegian (no)

Other versions

NO20014603D0 (no

Inventor

Shuichi Furuya

Nobuhiro Suzuki

Nobuo Choh

Yoshi Nara

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-24

Filing date

2001-09-21

Publication date

2001-11-26

2001-09-21 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

2001-09-21 Publication of NO20014603D0 publication Critical patent/NO20014603D0/no

2001-11-26 Publication of NO20014603L publication Critical patent/NO20014603L/no

Links

150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO20014603A 1999-03-24 2001-09-21 Tienopyrimidinforbindelser, deres fremstilling og anvendelse NO20014603L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP7937199		1999-03-24
JP2000018019		2000-01-25
PCT/JP2000/001777 WO2000056739A1 (en)	1999-03-24	2000-03-23	Thienopyrimidine compounds, their production and use

Publications (2)

Publication Number	Publication Date
NO20014603D0 NO20014603D0 (no)	2001-09-21
NO20014603L true NO20014603L (no)	2001-11-26

Family

ID=26420391

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20014603A NO20014603L (no)	1999-03-24	2001-09-21	Tienopyrimidinforbindelser, deres fremstilling og anvendelse

Country Status (28)

Country	Link
US (1)	US6340686B1 (id)
EP (1)	EP1163244B1 (id)
JP (1)	JP3240293B2 (id)
KR (2)	KR100533483B1 (id)
CN (1)	CN1349536A (id)
AR (1)	AR023152A1 (id)
AT (1)	ATE261449T1 (id)
AU (1)	AU764019B2 (id)
BR (1)	BR0009297A (id)
CA (1)	CA2368108C (id)
CZ (1)	CZ294747B6 (id)
DE (1)	DE60008862T2 (id)
DK (1)	DK1163244T3 (id)
ES (1)	ES2212992T3 (id)
HK (1)	HK1042495B (id)
HU (1)	HUP0200550A3 (id)
ID (1)	ID30393A (id)
IL (1)	IL145549A (id)
MX (1)	MXPA01009566A (id)
MY (1)	MY124726A (id)
NO (1)	NO20014603L (id)
NZ (1)	NZ514737A (id)
OA (1)	OA11920A (id)
PL (1)	PL351202A1 (id)
PT (1)	PT1163244E (id)
SK (1)	SK13552001A3 (id)
TW (1)	TWI225863B (id)
WO (1)	WO2000056739A1 (id)

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US6828415B2 (en) *	1993-02-19	2004-12-07	Zentaris Gmbh	Oligopeptide lyophilisate, their preparation and use
US6849738B2 (en) *	2000-02-29	2005-02-01	Takeda Chemical Industries, Ltd.	Processes for the production of thienopyrimidine derivatives
US20030134863A1 (en) *	2000-04-13	2003-07-17	Shuichi Furuya	Preventives/remedies for alzheimer's disease
US20040023987A1 (en) *	2000-06-14	2004-02-05	Yoshio Hata	Sustained release compositions
WO2002024230A1 (en) *	2000-09-22	2002-03-28	Takeda Chemical Industries, Ltd.	Solid preparations
AU2002218494A1 (en) *	2000-11-29	2002-06-11	Takeda Chemical Industries Ltd.	Medicinal compositions and process for producing the same
WO2002047722A1 (en) *	2000-12-15	2002-06-20	Takeda Chemical Industries, Ltd.	Medicinal compositions of nonpeptidyl gonadotropin-releasing hormone agonist or antagonist, process for producing the same and use thereof
WO2002078669A1 (fr) *	2001-03-30	2002-10-10	Takeda Chemical Industries, Ltd.	Solutions medicinales
EP1414808A1 (en)	2001-08-02	2004-05-06	Neurocrine Biosciences, Inc.	1,2,4-triazin-3,5-diones as gonadotropin-releasing hormone receptor (gnrh) antagonists
JP2005505525A (ja)	2001-08-02	2005-02-24	ニューロクラインバイオサイエンシーズ，インコーポレイテッド	性腺刺激ホルモン放出ホルモンレセプターアンタゴニストおよびそれに関連する方法
EP1412363A1 (en)	2001-08-02	2004-04-28	Neurocrine Biosciences, Inc.	Gonadotropin-releasing hormone receptor antagonists
JP2005504034A (ja)	2001-08-02	2005-02-10	ニューロクラインバイオサイエンシーズ，インコーポレイテッド	ゴナドトロピン放出性ホルモンレセプターアンタゴニストとしてのピリジノン誘導体およびピリダジノン誘導体
AU2002324586B2 (en)	2001-08-02	2008-04-24	Neurocrine Biosciences, Inc.	1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists
EP1479684A4 (en) *	2002-01-30	2006-01-04	Takeda Pharmaceutical	THIENOPYRIMIDINES, METHODS OF MAKING AND USING SAME
WO2003086464A1 (en)	2002-04-12	2003-10-23	Takeda Pharmaceutical Company Limited.	Preventives/remedies for hotflash
DE60318716T2 (de) *	2002-08-21	2009-01-08	Astrazeneca Ab	Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren
CN101153042A (zh)	2003-01-29	2008-04-02	武田药品工业株式会社	噻吩并嘧啶化合物及其用途
GB0307777D0 (en)	2003-04-04	2003-05-07	Medical Res Council	Conjugate compounds
US20060083017A1 (en) *	2004-10-18	2006-04-20	Bwt Propety, Inc.	Solid-state lighting apparatus for navigational aids
KR20080041662A (ko)	2005-07-22	2008-05-13	다케다 야쿠힌 고교 가부시키가이샤	조기 배란 예방제
US20110172249A1 (en)	2008-09-03	2011-07-14	Takeda Pharmaceutical Company Limted	Method for improving absorbability of preparation, and preparation having improved absorbability
US9481684B2 (en) *	2012-02-28	2016-11-01	Sk Chemicals Co., Ltd.	Gonadotropin releasing hormone receptor antagonists, method for the preparation thereof and pharmaceutical composition comprising the same
SMT202200255T1 (it)	2012-09-28	2022-07-21	Takeda Pharmaceuticals Co	Forma cristallina di 1-(4-1-(2,6-difluorobenzil)-5-dimetilamminometil-3-(6-metossipiridazin-3-il)-2,4-diosso-1,2,3,4-tetraidrotieno(2,3-d)-pirimidin-6il)fenil)-3-metossiurea
TWI744224B (zh)	2015-02-26	2021-11-01	日商武田藥品工業股份有限公司	固形製劑
WO2018060501A2 (en)	2016-09-30	2018-04-05	Myovant Sciences Gmbh	Methods of treating uterine fibroids and endometriosis
SI3518932T1 (sl)	2016-09-30	2025-03-31	Takeda Pharmaceutical Company Limited	Zdravljenje raka prostate
KR101973074B1 (ko) *	2018-11-30	2019-04-26	주식회사 티움바이오	퓨로피리미딘 화합물의 염 및 결정형, 및 이를 포함하는 약학적 조성물
WO2021018105A1 (en) *	2019-07-29	2021-02-04	Sunshine Lake Pharma Co., Ltd.	Substituted pyrimidinedione compounds and uses thereof
WO2021069700A1 (en)	2019-10-10	2021-04-15	Myovant Sciences Gmbh	Crystalline solvated forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
JP2022551316A (ja)	2019-10-10	2022-12-08	ミオバントサイエンシズゲーエムベーハー	Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素の結晶形
CN111574534B (zh) *	2020-05-25	2021-06-04	东莞市东阳光新药研发有限公司	苯基取代的噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮类化合物及其用途
BR112022023937A2 (pt)	2020-05-29	2022-12-27	Myovant Sciences Gmbh	Formas de dosagem oral sólidas de combinação de antagonistas do hormônio liberador de gonadotropina
CN111909168B (zh) *	2020-07-31	2022-02-01	广东东阳光药业有限公司	含氮杂环基取代的嘧啶二酮类化合物及其用途
CN111925379B (zh) *	2020-07-31	2022-02-15	广东东阳光药业有限公司	含氮杂芳基取代的嘧啶二酮类化合物及其用途
CN112047957B (zh) *	2020-09-09	2022-02-01	广东东阳光药业有限公司	取代的嘧啶二酮类化合物及其用途
CN113754679B (zh) *	2020-09-09	2023-04-07	广东东阳光药业有限公司	取代的嘧啶二酮类化合物及其用途
CN113563303B (zh) *	2020-12-30	2022-04-12	上海博志研新药物技术有限公司	瑞卢戈利中间体及其制备方法
CN115260211B (zh) *	2021-04-29	2024-02-06	长春金赛药业有限责任公司	含噻吩稠环类衍生物、药物组合物及其制备方法和应用
CN113717149A (zh) *	2021-09-29	2021-11-30	成都伊诺达博医药科技有限公司	一种瑞卢戈利关键中间体及其制备方法
CN119546611A (zh)	2022-05-05	2025-02-28	台湾神隆股份有限公司	瑞卢戈利的制备工艺及其中间体

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2000
- 2000-03-08 TW TW089104127A patent/TWI225863B/zh not_active IP Right Cessation
- 2000-03-21 MY MYPI20001112 patent/MY124726A/en unknown
- 2000-03-23 CZ CZ20013419A patent/CZ294747B6/cs not_active IP Right Cessation
- 2000-03-23 EP EP00911308A patent/EP1163244B1/en not_active Expired - Lifetime
- 2000-03-23 PT PT00911308T patent/PT1163244E/pt unknown
- 2000-03-23 NZ NZ514737A patent/NZ514737A/en unknown
- 2000-03-23 DK DK00911308T patent/DK1163244T3/da active
- 2000-03-23 WO PCT/JP2000/001777 patent/WO2000056739A1/en not_active Ceased
- 2000-03-23 MX MXPA01009566A patent/MXPA01009566A/es active IP Right Grant
- 2000-03-23 JP JP2000087051A patent/JP3240293B2/ja not_active Expired - Fee Related
- 2000-03-23 BR BR0009297-5A patent/BR0009297A/pt not_active IP Right Cessation
- 2000-03-23 KR KR10-2000-7011511A patent/KR100533483B1/ko not_active Expired - Fee Related
- 2000-03-23 AU AU33262/00A patent/AU764019B2/en not_active Ceased
- 2000-03-23 HU HU0200550A patent/HUP0200550A3/hu unknown
- 2000-03-23 KR KR10-2000-7011508A patent/KR100370981B1/ko not_active Expired - Fee Related
- 2000-03-23 PL PL00351202A patent/PL351202A1/xx not_active Application Discontinuation
- 2000-03-23 IL IL14554900A patent/IL145549A/xx not_active IP Right Cessation
- 2000-03-23 OA OA1200100243A patent/OA11920A/en unknown
- 2000-03-23 CN CN00807210A patent/CN1349536A/zh active Pending
- 2000-03-23 HK HK02104325.6A patent/HK1042495B/en not_active IP Right Cessation
- 2000-03-23 CA CA002368108A patent/CA2368108C/en not_active Expired - Fee Related
- 2000-03-23 ID IDW00200102298A patent/ID30393A/id unknown
- 2000-03-23 SK SK1355-2001A patent/SK13552001A3/sk unknown
- 2000-03-23 AT AT00911308T patent/ATE261449T1/de not_active IP Right Cessation
- 2000-03-23 DE DE60008862T patent/DE60008862T2/de not_active Expired - Lifetime
- 2000-03-23 ES ES00911308T patent/ES2212992T3/es not_active Expired - Lifetime
- 2000-03-24 AR ARP000101320A patent/AR023152A1/es not_active Application Discontinuation
- 2000-05-16 US US09/571,215 patent/US6340686B1/en not_active Expired - Lifetime
2001
- 2001-09-21 NO NO20014603A patent/NO20014603L/no unknown

Also Published As

Publication number	Publication date
NZ514737A (en)	2003-10-31
BR0009297A (pt)	2001-12-18
KR20010015920A (ko)	2001-02-26
AR023152A1 (es)	2002-09-04
KR100370981B1 (ko)	2003-02-06
SK13552001A3 (sk)	2002-03-05
DK1163244T3 (da)	2004-07-12
CN1349536A (zh)	2002-05-15
OA11920A (en)	2006-04-12
HUP0200550A3 (en)	2004-07-28
AU3326200A (en)	2000-10-09
PT1163244E (pt)	2004-07-30
AU764019B2 (en)	2003-08-07
HK1042495A1 (en)	2002-08-16
EP1163244B1 (en)	2004-03-10
KR20010090430A (ko)	2001-10-18
CZ20013419A3 (cs)	2002-02-13
IL145549A (en)	2005-11-20
DE60008862T2 (de)	2005-01-27
ATE261449T1 (de)	2004-03-15
CA2368108C (en)	2009-12-22
DE60008862D1 (de)	2004-04-15
ES2212992T3 (es)	2004-08-16
KR100533483B1 (ko)	2005-12-05
CA2368108A1 (en)	2000-09-28
MXPA01009566A (es)	2002-05-14
CZ294747B6 (cs)	2005-03-16
EP1163244A1 (en)	2001-12-19
MY124726A (en)	2006-06-30
JP3240293B2 (ja)	2001-12-17
NO20014603D0 (no)	2001-09-21
WO2000056739A1 (en)	2000-09-28
ID30393A (id)	2001-11-29
US6340686B1 (en)	2002-01-22
HUP0200550A2 (en)	2002-06-29
TWI225863B (en)	2005-01-01
IL145549A0 (en)	2002-06-30
JP2001278884A (ja)	2001-10-10
PL351202A1 (en)	2003-03-24
HK1042495B (en)	2004-10-08

Publication	Publication Date	Title
NO20015156L (no)	2001-12-18	5-pyridyl-1,3-azolforbindelser, deres fremstilling og anvendelse
NO20014603D0 (no)	2001-09-21	Tienopyrimidinforbindelser, deres fremstilling og anvendelse
NO20021449L (no)	2002-05-07	Substituerte 2-tio-3,5-dicyano-4-aryl-6-aminopyridiner og deres anvendelse
NO20024742D0 (no)	2002-10-02	Heterocykliske forbindelser, deres fremstilling og anvendelse
NO20015113D0 (no)	2001-10-19	Nye forbindelser, deres fremstilling og anvendelse
NO20012567D0 (no)	2001-05-25	Azepinoindolderivater, fremstilling og anvendelse derav
NO20011956D0 (no)	2001-04-20	Substituerte fenylderivater, deres fremstilling og anvendelse
DK1073672T3 (da)	2003-12-08	Antipicornavirale forbindelser, deres fremstilling og anvendelse
NO20024175D0 (no)	2002-09-02	Azetidinderivater, deres fremstilling og farmasöytiske forbindelser inneholdende de samme
DK1095025T3 (da)	2003-04-07	Benzimidazoler, deres fremstilling og deres anvendelse som lægemidler
NO20005146L (no)	2000-12-14	Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter
DK1161434T3 (da)	2003-05-26	Pyridopyranoazepinderivater, deres fremstilling og terapeutiske anvendelse
NO20031838D0 (no)	2003-04-24	Benzokazinonderivater, deres fremstilling og anvendelse
EE200200150A (et)	2003-04-15	Preparaat
DK1043307T3 (da)	2003-09-22	3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
NO20023146D0 (no)	2002-06-28	Substituerte fenyl-piperazinderivater, deres fremstilling og anvendelse
NO20020156D0 (no)	2002-01-11	Titanavledede forbindelser, fremstilling og anvendelse derav
NO20022022L (no)	2002-04-29	N-guanidinoalkylamider, deres fremstilling, deres anvendelse og farmasöytiske preparater omfattende disse
NO20024107L (no)	2002-09-27	Tienopyridin derivater, deres fremstilling og anvendelse
NO20006479D0 (no)	2000-12-19	Tienopyridinforbindelser, deres fremstilling og anvendelse
NO20025209L (no)	2002-10-30	Cyklipostiner, deres fremstilling og anvendelse
NO20001782L (no)	2000-10-09	3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
NO996156L (no)	2000-06-15	Substituerte cykloheptener, deres fremstilling og anvendelse
NO20012802D0 (no)	2001-06-07	Benzofuranderivater, deres fremstilling og anvendelse
NO20011921L (no)	2001-10-29	Sulfidoamidokarboksylsyre, deres fremstilling og anvendelse