NO20016270L - Vektorer, celler og fremgangsmåter for fremstilling av pyrimidindeoksyribonukleosider - Google Patents

Vektorer, celler og fremgangsmåter for fremstilling av pyrimidindeoksyribonukleosider

Info

Publication number
NO20016270L
NO20016270L NO20016270A NO20016270A NO20016270L NO 20016270 L NO20016270 L NO 20016270L NO 20016270 A NO20016270 A NO 20016270A NO 20016270 A NO20016270 A NO 20016270A NO 20016270 L NO20016270 L NO 20016270L
Authority
NO
Norway
Prior art keywords
sequences encoding
constructs
dna
host cells
gene
Prior art date
Application number
NO20016270A
Other languages
English (en)
Norwegian (no)
Other versions
NO20016270D0 (no
Inventor
David Martin Anderson
Lin Liu
Sergey Podkovyrov
Baomin Wang
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/345,492 external-priority patent/US20020128457A1/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20016270D0 publication Critical patent/NO20016270D0/no
Publication of NO20016270L publication Critical patent/NO20016270L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0093—Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/385—Pyrimidine nucleosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
NO20016270A 1999-07-01 2001-12-20 Vektorer, celler og fremgangsmåter for fremstilling av pyrimidindeoksyribonukleosider NO20016270L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14182799P 1999-07-01 1999-07-01
US09/345,492 US20020128457A1 (en) 1999-07-01 1999-07-01 Vectors, cells and processes for pyrimidine deoxyribonucleosides production
PCT/GB2000/002357 WO2001002580A1 (en) 1999-07-01 2000-06-30 Vectors, cells and processes for pyrimidine deoxyribonucleosides production

Publications (2)

Publication Number Publication Date
NO20016270D0 NO20016270D0 (no) 2001-12-20
NO20016270L true NO20016270L (no) 2002-02-21

Family

ID=26839484

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20016270A NO20016270L (no) 1999-07-01 2001-12-20 Vektorer, celler og fremgangsmåter for fremstilling av pyrimidindeoksyribonukleosider

Country Status (13)

Country Link
US (2) US6777209B1 (cs)
EP (1) EP1190064B1 (cs)
JP (1) JP2003504029A (cs)
KR (1) KR20020019938A (cs)
AT (1) ATE368743T1 (cs)
AU (1) AU5547700A (cs)
CZ (1) CZ301565B6 (cs)
DE (1) DE60035781T2 (cs)
ES (1) ES2290041T3 (cs)
IL (1) IL147225A0 (cs)
MX (1) MXPA02000134A (cs)
NO (1) NO20016270L (cs)
WO (1) WO2001002580A1 (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7723097B2 (en) * 2005-03-11 2010-05-25 Archer-Daniels-Midland Company Escherichia coli strains that over-produce L-threonine and processes for their production
GB0602339D0 (en) * 2006-02-06 2006-03-15 Glaxo Group Ltd Novel process
JP2012125197A (ja) * 2010-12-16 2012-07-05 Kyowa Hakko Kirin Co Ltd タンパク質の生産方法
CN111748537B (zh) * 2020-08-04 2021-11-26 浙江华睿生物技术有限公司 一种尿苷磷酸酶突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH022349A (ja) * 1988-02-17 1990-01-08 Takeda Chem Ind Ltd ピリミジンアナログ耐性化遺伝子ｄｎａおよびその用途
ATE108487T1 (de) * 1988-05-31 1994-07-15 Zeneca Ltd Herstellung eines desoxyribonucleosids.
US5213972A (en) * 1989-12-08 1993-05-25 Chemgen Corporation Fermentation process for the production of pyrimidine deoxyribonucleosides

Also Published As

Publication number Publication date
NO20016270D0 (no) 2001-12-20
ATE368743T1 (de) 2007-08-15
JP2003504029A (ja) 2003-02-04
US20050009083A1 (en) 2005-01-13
IL147225A0 (en) 2002-08-14
US6777209B1 (en) 2004-08-17
MXPA02000134A (es) 2002-07-30
CZ20014695A3 (cs) 2002-04-17
WO2001002580A1 (en) 2001-01-11
DE60035781D1 (de) 2007-09-13
CZ301565B6 (cs) 2010-04-14
ES2290041T3 (es) 2008-02-16
DE60035781T2 (de) 2008-08-07
KR20020019938A (ko) 2002-03-13
EP1190064A1 (en) 2002-03-27
AU5547700A (en) 2001-01-22
US7387893B2 (en) 2008-06-17
EP1190064B1 (en) 2007-08-01

Similar Documents

Publication Publication Date Title
WO2005040377A3 (en) High efficiency gene transfer and expression in mammalian cells by a multiple transfection procedure of matrix attachment region sequences
AU6857696A (en) Methods for enhancing the production of interferon in cell culture
EP1476562A4 (en) OVEREXPRESSION OF EXTREMOZYME GENES IN PSEUDOMONAL BACTERIA AND CLOSELY BOUNDED BACTERIA
TNSN07142A1 (en) Enzymes
ATE448298T1 (de) Il-21-produktion in prokaryontischen wirten
WO2006012221A3 (en) Target cell-specific short interfering rna and methods of use thereof
WO2003006613A3 (en) Methods for ex vivo propagation of somatic stem cells
Suzuki et al. Misincorporation of 2 ‘-deoxyoxanosine 5 ‘-triphosphate by DNA polymerases and its implication for mutagenesis
WO2001062938A3 (en) Variant galactose oxidase, nucleic acid encoding same, and methods of using same
WO2003008575A3 (en) Dna sequences for regulating transcription
PL345851A1 (en) Polyketides, their preparation, and materials for use therein
WO1999049058A3 (en) Tryptophan biosynthetic enzymes
NO20016270L (no) Vektorer, celler og fremgangsmåter for fremstilling av pyrimidindeoksyribonukleosider
WO2002100898A3 (en) Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same
JPH05504055A (ja) ピリミジンデオキシリボヌクレオシドの製造用発酵方法
EP1806405A3 (en) Vectors, cells and processes for pyrimidine deoxyribonucleosides production
WO2003062383A3 (en) In vivo gene transfer
AU2003260200A1 (en) Reversible, parallel and multitask cloning method and kit
AU2294102A (en) Mutant muscle-specific enhancers
WO2003066867A3 (en) Genetically engineered phic31-integrase genes
AU5206899A (en) Uses of dna-pk
Kirsebom et al. Functional interactions in vivo between suppressor tRNA and mutationally altered ribosomal protein S4
WO2003014393A1 (fr) Methode de detection, d'identification et de comptage des vibrions de l'enterite au moyen de sequences de gene (rpdo) codant pour le facteur $g(s)70 de l'arn polymerase
WO2003012108A3 (fr) Utilisations d'un polypeptide thyx d'un acide nucleique codant un tel polypeptide, notamment pour le criblage de composes anti-bacteriens ou anti-viraux.
WO2001046393A3 (en) Aspartate kinase

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application