NO20023014L - Fremgangsmåte for fremstilling av 4-(heteroarylmetyl)-halogen- 1(2H)-ftalaziononer - Google Patents

Fremgangsmåte for fremstilling av 4-(heteroarylmetyl)-halogen- 1(2H)-ftalaziononer

Info

Publication number: NO20023014L
Authority: NO; Norway
Prior art keywords: phthalazionones; heteroarylmethyl; halo; preparation; reaction
Prior art date: 1999-12-23

Application number

NO20023014A

Other languages

English (en)

Other versions

NO321357B1 (no

NO20023014D0 (no

Inventor

Orlin Petrov

Tamas Heiner

Harribert Neh

Martin Krueger

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-23

Filing date

2002-06-21

Publication date

2002-06-21

2002-06-21 Application filed by Schering Ag filed Critical Schering Ag

2002-06-21 Publication of NO20023014L publication Critical patent/NO20023014L/no

2002-06-21 Publication of NO20023014D0 publication Critical patent/NO20023014D0/no

2006-05-02 Publication of NO321357B1 publication Critical patent/NO321357B1/no

Links

238000000034 method Methods 0.000 title abstract 4
NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 abstract 1
NIQMWTLRDNQDIA-UHFFFAOYSA-N 4-(pyridin-4-ylmethyl)-2h-phthalazin-1-one Chemical compound C12=CC=CC=C2C(=O)NN=C1CC1=CC=NC=C1 NIQMWTLRDNQDIA-UHFFFAOYSA-N 0.000 abstract 1
238000010306 acid treatment Methods 0.000 abstract 1
239000002671 adjuvant Substances 0.000 abstract 1
230000007613 environmental effect Effects 0.000 abstract 1
IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
BGUWFUQJCDRPTL-UHFFFAOYSA-N pyridine-4-carbaldehyde Chemical compound O=CC1=CC=NC=C1 BGUWFUQJCDRPTL-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Catalysts (AREA)

NO20023014A 1999-12-23 2002-06-21 Fremgangsmate for fremstilling av 4-(heteroarylmetyl)-halogen-1(2H)-ftalazinoner NO321357B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19963607A DE19963607B4 (de)	1999-12-23	1999-12-23	Verfahren zur Herstellung von 4-(Heteroaryl-methyl) halogen-1(2H)-phthalazinonen
PCT/EP2000/013027 WO2001047912A1 (de)	1999-12-23	2000-12-20	Verfahren zur herstellung von 4-(heteroaryl-methyl)-halogen-1(2h)-phthalazinonen

Publications (3)

Publication Number	Publication Date
NO20023014L true NO20023014L (no)	2002-06-21
NO20023014D0 NO20023014D0 (no)	2002-06-21
NO321357B1 NO321357B1 (no)	2006-05-02

Family

ID=7934888

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20023014A NO321357B1 (no)	1999-12-23	2002-06-21	Fremgangsmate for fremstilling av 4-(heteroarylmetyl)-halogen-1(2H)-ftalazinoner

Country Status (31)

Country	Link
US (1)	US6891041B2 (no)
EP (1)	EP1242405B1 (no)
JP (1)	JP2003529555A (no)
KR (1)	KR100654265B1 (no)
CN (1)	CN1221545C (no)
AT (1)	ATE273972T1 (no)
AU (1)	AU772981B2 (no)
BG (1)	BG65387B1 (no)
BR (1)	BR0016634A (no)
CA (1)	CA2395407C (no)
CZ (1)	CZ20022146A3 (no)
DE (2)	DE19963607B4 (no)
DK (1)	DK1242405T3 (no)
EE (1)	EE04940B1 (no)
ES (1)	ES2223626T3 (no)
HR (1)	HRP20020605B1 (no)
HU (1)	HUP0300992A3 (no)
IL (2)	IL150017A0 (no)
MX (1)	MXPA02006224A (no)
NO (1)	NO321357B1 (no)
NZ (1)	NZ519285A (no)
PL (1)	PL200714B1 (no)
PT (1)	PT1242405E (no)
RO (1)	RO121211B1 (no)
RS (1)	RS50458B (no)
RU (1)	RU2250900C2 (no)
SI (1)	SI1242405T1 (no)
SK (1)	SK285522B6 (no)
UA (1)	UA72021C2 (no)
WO (1)	WO2001047912A1 (no)
ZA (1)	ZA200205853B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1296984B1 (it) *	1997-12-19	1999-08-03	Zambon Spa	Derivati ftalazinici inibitori della fosfodiesterasi 4
US7151102B2 (en) *	2000-10-30	2006-12-19	Kudos Pharmaceuticals Limited	Phthalazinone derivatives
GB0419072D0 (en)	2004-08-26	2004-09-29	Kudos Pharm Ltd	Phthalazinone derivatives
UY30639A1 (es) *	2006-10-17	2008-05-31	Kudos Pharm Ltd	Derivados sustituidos de 2h-ftalazin-1-ona, sus formas cristalinas, proceso de preparacion y aplicaciones
CA2702429A1 (en) *	2007-10-17	2009-04-23	Kudos Pharmaceuticals Limited	Crystalline form l 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phthalazin-1-one
ES2598178T5 (es)	2008-10-07	2023-12-26	Kudos Pharm Ltd	Formulación farmacéutica 514
MX365950B (es)	2013-03-13	2019-06-19	Flatley Discovery Lab Llc	Compuestos de piridazinona y metodos para el tratamiento de la fibrosis quistica.
BR112017011831A2 (pt) *	2015-03-19	2017-12-26	Clariant Int Ltd	tensoativos de amido açúcar biodegradáveis para recuperação avançada de petróleo

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE567431A (no) *	1957-05-07
GB1293565A (en) *	1969-05-03	1972-10-18	Aspro Nicholas Ltd	Aminophthalazines and pharmaceutical compositions thereof
IE47592B1 (en) *	1977-12-29	1984-05-02	Ici Ltd	Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
EP0634404A1 (en) *	1993-07-13	1995-01-18	Rhone Poulenc Agriculture Ltd.	Phtalazin derivatives and their use as pesticides
WO1996005176A1 (en) *	1994-08-09	1996-02-22	Eisai Co., Ltd.	Fused pyridazine compound
RU2128175C1 (ru) *	1994-08-09	1999-03-27	Эйсай Ко., Лтд.	Конденсированный пиридазин или его фармакологически приемлемая соль, средство, проявляющее ингибирующую активность в отношении циклической гмф- фосфодиэстеразы
JP3919835B2 (ja) *	1994-08-09	2007-05-30	エーザイ・アール・アンド・ディー・マネジメント株式会社	縮合ピリダジン系化合物
DE69720515T2 (de) *	1996-12-18	2004-02-19	Neurogen Corp., Branford	Isoquinolinamin und phtalazinamin derivate, die reagieren mit crf rezeptoren
CO4950519A1 (es) *	1997-02-13	2000-09-01	Novartis Ag	Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
IT1296984B1 (it) *	1997-12-19	1999-08-03	Zambon Spa	Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI981671A1 (it) *	1998-07-21	2000-01-21	Zambon Spa	Derivati ftalazinici inibitori della fosfodisterasi 4
ITMI981670A1 (it) *	1998-07-21	2000-01-21	Zambon Spa	Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI20000261A1 (it) *	2000-02-16	2001-08-16	Zambon Group	Processo per la preparazione di piridiniliden-ftalidi

1999
- 1999-12-23 DE DE19963607A patent/DE19963607B4/de not_active Expired - Fee Related
2000
- 2000-12-20 MX MXPA02006224A patent/MXPA02006224A/es active IP Right Grant
- 2000-12-20 RO ROA200200653A patent/RO121211B1/ro unknown
- 2000-12-20 CZ CZ20022146A patent/CZ20022146A3/cs unknown
- 2000-12-20 IL IL15001700A patent/IL150017A0/xx active IP Right Grant
- 2000-12-20 EE EEP200200307A patent/EE04940B1/xx not_active IP Right Cessation
- 2000-12-20 SK SK892-2002A patent/SK285522B6/sk not_active IP Right Cessation
- 2000-12-20 JP JP2001549382A patent/JP2003529555A/ja active Pending
- 2000-12-20 PT PT00983354T patent/PT1242405E/pt unknown
- 2000-12-20 KR KR1020027007997A patent/KR100654265B1/ko not_active Expired - Fee Related
- 2000-12-20 AU AU20122/01A patent/AU772981B2/en not_active Ceased
- 2000-12-20 RU RU2002119559/04A patent/RU2250900C2/ru not_active IP Right Cessation
- 2000-12-20 SI SI200030486T patent/SI1242405T1/xx unknown
- 2000-12-20 WO PCT/EP2000/013027 patent/WO2001047912A1/de not_active Ceased
- 2000-12-20 CN CNB008175608A patent/CN1221545C/zh not_active Expired - Fee Related
- 2000-12-20 CA CA002395407A patent/CA2395407C/en not_active Expired - Fee Related
- 2000-12-20 HU HU0300992A patent/HUP0300992A3/hu unknown
- 2000-12-20 NZ NZ519285A patent/NZ519285A/xx unknown
- 2000-12-20 BR BR0016634-0A patent/BR0016634A/pt not_active Application Discontinuation
- 2000-12-20 ES ES00983354T patent/ES2223626T3/es not_active Expired - Lifetime
- 2000-12-20 DK DK00983354T patent/DK1242405T3/da active
- 2000-12-20 US US10/168,794 patent/US6891041B2/en not_active Expired - Fee Related
- 2000-12-20 UA UA2002076049A patent/UA72021C2/uk unknown
- 2000-12-20 HR HR20020605A patent/HRP20020605B1/xx not_active IP Right Cessation
- 2000-12-20 AT AT00983354T patent/ATE273972T1/de not_active IP Right Cessation
- 2000-12-20 DE DE50007520T patent/DE50007520D1/de not_active Expired - Fee Related
- 2000-12-20 RS YUP-473/02A patent/RS50458B/sr unknown
- 2000-12-20 PL PL355525A patent/PL200714B1/pl not_active IP Right Cessation
- 2000-12-20 EP EP00983354A patent/EP1242405B1/de not_active Expired - Lifetime
2002
- 2002-06-04 IL IL150017A patent/IL150017A/en not_active IP Right Cessation
- 2002-06-19 BG BG106843A patent/BG65387B1/bg unknown
- 2002-06-21 NO NO20023014A patent/NO321357B1/no not_active IP Right Cessation
- 2002-07-22 ZA ZA200205853A patent/ZA200205853B/en unknown

Also Published As

Publication number	Publication date
PT1242405E (pt)	2004-11-30
HRP20020605A2 (en)	2004-12-31
PL200714B1 (pl)	2009-01-30
HK1055296A1 (en)	2004-01-02
ES2223626T3 (es)	2005-03-01
IL150017A (en)	2006-12-31
AU2012201A (en)	2001-07-09
US20040192695A1 (en)	2004-09-30
SK8922002A3 (en)	2002-11-06
JP2003529555A (ja)	2003-10-07
SK285522B6 (sk)	2007-03-01
DE50007520D1 (de)	2004-09-23
BR0016634A (pt)	2002-10-15
EE04940B1 (et)	2007-12-17
PL355525A1 (en)	2004-05-04
NZ519285A (en)	2004-12-24
SI1242405T1 (en)	2005-02-28
EP1242405A1 (de)	2002-09-25
US6891041B2 (en)	2005-05-10
RS50458B (sr)	2010-03-02
BG106843A (en)	2003-02-28
HUP0300992A2 (hu)	2003-08-28
DE19963607A1 (de)	2001-07-12
EP1242405B1 (de)	2004-08-18
DE19963607B4 (de)	2005-12-15
CA2395407A1 (en)	2001-07-05
ATE273972T1 (de)	2004-09-15
ZA200205853B (en)	2004-02-18
MXPA02006224A (es)	2002-12-05
NO321357B1 (no)	2006-05-02
RO121211B1 (ro)	2007-01-30
CA2395407C (en)	2009-04-28
KR100654265B1 (ko)	2006-12-07
AU772981B2 (en)	2004-05-13
WO2001047912A1 (de)	2001-07-05
CZ20022146A3 (cs)	2002-09-11
HRP20020605B1 (en)	2007-06-30
CN1221545C (zh)	2005-10-05
EE200200307A (et)	2003-06-16
CN1413203A (zh)	2003-04-23
RU2002119559A (ru)	2004-01-10
UA72021C2 (en)	2005-01-17
DK1242405T3 (da)	2004-11-01
RU2250900C2 (ru)	2005-04-27
IL150017A0 (en)	2002-12-01
HUP0300992A3 (en)	2005-11-28
KR20020062363A (ko)	2002-07-25
BG65387B1 (bg)	2008-05-30
NO20023014D0 (no)	2002-06-21
YU47302A (sh)	2005-06-10

Legal Events

Date	Code	Title	Description
2010-07-19	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
CA2384283A1 (en)	2001-05-03	Process for preparing 4-trifluoromethylsulphinylpyrazole derivative
NO20023014L (no)	2002-06-21	Fremgangsmåte for fremstilling av 4-(heteroarylmetyl)-halogen- 1(2H)-ftalaziononer
DK1242388T3 (da)	2003-11-17	Fremgangsmåde til fremstilling af et triazolinthion-derivat
HUP0303343A2 (hu)	2004-01-28	Eljárás hemicellulózok elválasztására hemicellulóz-tartalmú biomasszából és az eljárással előállított biomassza és hemicellulóz
ATE321758T1 (de)	2006-04-15	Verbessertes verfahren zur herstellung von verbindungen des benzimidazoltyps
CA2295817A1 (en)	1999-01-21	Method for producing pyridine compound
CA2513555C (en)	2012-09-11	Process for the preparation of pyridylsulfinylbenzimidazoles
MXPA03006904A (es)	2004-12-06	Procesos para la produccion de 2-(2-piridilmetil) sulfinil - 1h - bencimidazoles sustituidos.
EA200400792A1 (ru)	2004-10-28	Напиток, обработанный никотином
JP2003529555A5 (no)	2008-02-14
KR0133855B1 (ko)	1998-04-23	4-메틸피라졸류의 제조방법
TWI263637B (en)	2006-10-11	Process for preparing nicotinic acid and catalyst used in the method
Sadowski	2024	Alternative synthetic protocols as a way to mask unreliability in organic chemistry research, case of nitrones
ATE315004T1 (de)	2006-02-15	Verbessertes verfahren zur herstellung hochkonzentrierter hydroxylaminlösungen
WO2005077370A8 (ja)	2006-01-05	カンプトテシン類含有水溶液製剤
Kuthan	1994	Extension of Decker oxidation
RU2002103882A (ru)	2003-12-10	Аминогуанидин-бикарбонат с особыми свойствами и способ его получения
MX2011005981A (es)	2011-06-27	Nuevo proceso para preparar 4-[4-metil-5-(alquiltio c1-10/aril c5-10-alquilto c1-6)-4h-1,2,4-triazol-3-il]piridinas.
JPH089599B2 (ja)	1996-01-31	ピラゾールカルボン酸類の製造方法
WO2004014309A3 (en)	2004-06-24	Improved process for hydroxyazapirones
CA2200607A1 (en)	1996-05-09	Processes and intermediates for preparing 5,7-dihydro-3-[2-{1-benzylpiperidin-4-yl}ethyl]-6h-pyrrolo-[4,5-f]-1,2-benzisoxazol-6-one
DK1189836T3 (da)	2004-04-05	Fremgangsmåde til stabilisering af hydrogenperoxid
IL152707A0 (en)	2003-06-24	Process for the preparation of 2,3-pentanedione
Strakova et al.	1995	Derivatives of 1-(2-pyridyl)-4, 5, 6, 7-tetrahydroindazole
KR840005106A (ko)	1984-11-03	화학적 방법