NO20024745L - 2-hydroksymutilinkarbamat-derivater for antibakteriell anvendelse - Google Patents

2-hydroksymutilinkarbamat-derivater for antibakteriell anvendelse

Info

Publication number
NO20024745L
NO20024745L NO20024745A NO20024745A NO20024745L NO 20024745 L NO20024745 L NO 20024745L NO 20024745 A NO20024745 A NO 20024745A NO 20024745 A NO20024745 A NO 20024745A NO 20024745 L NO20024745 L NO 20024745L
Authority
NO
Norway
Prior art keywords
hydroxymutiline
carbamate derivatives
antibacterial use
antibacterial
carbamate
Prior art date
Application number
NO20024745A
Other languages
English (en)
Other versions
NO324229B1 (no
NO20024745D0 (no
Inventor
Gerald Brooks
Eric Hunt
Steven Howard
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0008260.2A external-priority patent/GB0008260D0/en
Priority claimed from GB0027182A external-priority patent/GB0027182D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO20024745D0 publication Critical patent/NO20024745D0/no
Publication of NO20024745L publication Critical patent/NO20024745L/no
Publication of NO324229B1 publication Critical patent/NO324229B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
NO20024745A 2000-04-04 2002-10-02 2-hydroksymutilinkarbamat-derivater, anvendelse derav, farmasoytisk sammensetning samt fremgangsmate for fremstilling av en slik forbindelse NO324229B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0008260.2A GB0008260D0 (en) 2000-04-04 2000-04-04 Novel compounds
GB0027182A GB0027182D0 (en) 2000-11-04 2000-11-04 Novel comounds
PCT/EP2001/003594 WO2001074788A1 (en) 2000-04-04 2001-03-29 2-hydroxy-mutilin carbamate derivatives for antibacterial use

Publications (3)

Publication Number Publication Date
NO20024745D0 NO20024745D0 (no) 2002-10-02
NO20024745L true NO20024745L (no) 2002-11-19
NO324229B1 NO324229B1 (no) 2007-09-10

Family

ID=26244040

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20024745A NO324229B1 (no) 2000-04-04 2002-10-02 2-hydroksymutilinkarbamat-derivater, anvendelse derav, farmasoytisk sammensetning samt fremgangsmate for fremstilling av en slik forbindelse

Country Status (21)

Country Link
US (1) US6972297B2 (no)
EP (1) EP1268443B1 (no)
JP (1) JP2003529593A (no)
KR (1) KR100758441B1 (no)
CN (1) CN1210267C (no)
AR (1) AR030203A1 (no)
AT (1) ATE437860T1 (no)
AU (2) AU2001263827B2 (no)
BR (1) BR0109809A (no)
CA (1) CA2405132A1 (no)
CO (1) CO5280223A1 (no)
CZ (1) CZ20023290A3 (no)
DE (1) DE60139382D1 (no)
ES (1) ES2328109T3 (no)
HU (1) HUP0300370A3 (no)
IL (1) IL151887A0 (no)
MX (1) MXPA02009816A (no)
NO (1) NO324229B1 (no)
NZ (1) NZ521536A (no)
PL (1) PL358666A1 (no)
WO (1) WO2001074788A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0024811D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
US7176310B1 (en) 2002-04-09 2007-02-13 Ucb Sa Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents
GB0209262D0 (en) * 2002-04-23 2002-06-05 Biochemie Gmbh Organic compounds
ES2295657T3 (es) * 2002-07-24 2008-04-16 Nabriva Therapeutics Forschungs Gmbh Derivados de pleuromutilina como antimicrobianos.
GB0218578D0 (en) * 2002-08-09 2002-09-18 Glaxo Group Ltd Novel method
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
FR2856685B1 (fr) * 2003-06-25 2005-09-23 Merck Sante Sas Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
WO2006063801A1 (en) * 2004-12-13 2006-06-22 Glaxo Group Limited Novel polymorph of (5-amino-6-methoxy-3-pyridincarbonyl)carbamic acid 2-(s)-hydroxymutilin 14-ester
US20080221330A1 (en) * 2004-12-27 2008-09-11 Masanori Takadoi Mutilin-Derivative Substituted at Position 12
WO2006099196A1 (en) * 2005-03-10 2006-09-21 Smithkline Beecham Corporation Novel method
TW200738701A (en) 2005-07-26 2007-10-16 Du Pont Fungicidal carboxamides
KR100695541B1 (ko) * 2005-10-31 2007-03-16 한국단자공업 주식회사 연결터미널
WO2007079173A2 (en) * 2005-12-30 2007-07-12 Emergent Biosolutions Inc. Novel 2-heteroaryloxy-phenol derivatives as antibacterial agents
CA2688008A1 (en) * 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
EP2014640A1 (en) * 2007-07-13 2009-01-14 Nabriva Therapeutics AG Pleuromutilin derivatives
JP2010100582A (ja) * 2008-10-24 2010-05-06 Kyorin Pharmaceut Co Ltd １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
EP2184273A1 (de) 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
EP2253617A1 (de) 2009-05-20 2010-11-24 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
KR102656841B1 (ko) 2015-06-17 2024-04-12 나브리바 테라퓨틱스 게엠베하 레파뮬린의 주사가능한 약제학적 제형
CA3130138A1 (en) * 2019-02-27 2020-09-03 Oticara, Inc. Method for treating nasal, sinonasal, and nasopharyngeal tissue infection and/or inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4163254B2 (ja) 1996-01-03 2008-10-08 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ムチリンのカルバモイルオキシ誘導体および抗細菌剤としてのそれらの使用
HUP0001741A3 (en) 1996-08-02 2000-11-28 Smithkline Beecham Plc Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use
UY25225A1 (es) 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
FR2771008B1 (fr) 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
GB9817029D0 (en) 1998-08-05 1998-09-30 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
HUP0300370A3 (en) 2005-07-28
KR20030011815A (ko) 2003-02-11
EP1268443A1 (en) 2003-01-02
AR030203A1 (es) 2003-08-13
US20030114674A1 (en) 2003-06-19
NO324229B1 (no) 2007-09-10
KR100758441B1 (ko) 2007-09-14
NO20024745D0 (no) 2002-10-02
ATE437860T1 (de) 2009-08-15
CN1210267C (zh) 2005-07-13
WO2001074788A8 (en) 2001-12-20
CN1427827A (zh) 2003-07-02
MXPA02009816A (es) 2003-03-27
AU6382701A (en) 2001-10-15
CO5280223A1 (es) 2003-05-30
PL358666A1 (en) 2004-08-09
ES2328109T3 (es) 2009-11-10
IL151887A0 (en) 2003-04-10
WO2001074788A1 (en) 2001-10-11
BR0109809A (pt) 2003-01-21
NZ521536A (en) 2004-05-28
HUP0300370A2 (hu) 2003-06-28
DE60139382D1 (de) 2009-09-10
AU2001263827B2 (en) 2004-06-17
JP2003529593A (ja) 2003-10-07
EP1268443B1 (en) 2009-07-29
CA2405132A1 (en) 2001-10-11
US6972297B2 (en) 2005-12-06
CZ20023290A3 (cs) 2003-03-12

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