NO20025355L - Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII - Google Patents

Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII

Info

Publication number
NO20025355L
NO20025355L NO20025355A NO20025355A NO20025355L NO 20025355 L NO20025355 L NO 20025355L NO 20025355 A NO20025355 A NO 20025355A NO 20025355 A NO20025355 A NO 20025355A NO 20025355 L NO20025355 L NO 20025355L
Authority
NO
Norway
Prior art keywords
factor
pharmaceutical composition
xiii
viia
factor viia
Prior art date
Application number
NO20025355A
Other languages
English (en)
Norwegian (no)
Other versions
NO20025355D0 (no
Inventor
Lars Christian Petersen
Ulla Hedner
Rasmus Roejkjaer
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO20025355D0 publication Critical patent/NO20025355D0/no
Publication of NO20025355L publication Critical patent/NO20025355L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
NO20025355A 2000-05-10 2002-11-08 Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII NO20025355L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200000778 2000-05-10
DKPA200000771 2000-05-10
DKPA200000871 2000-06-06
PCT/DK2001/000322 WO2001085198A1 (en) 2000-05-10 2001-05-10 tHARMACEUTICAL COMPOSITION COMPRISING A FACTOR VIIA AND A FACTOR XIII

Publications (2)

Publication Number Publication Date
NO20025355D0 NO20025355D0 (no) 2002-11-08
NO20025355L true NO20025355L (no) 2003-01-09

Family

ID=27222387

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025355A NO20025355L (no) 2000-05-10 2002-11-08 Farmasöytisk preparat som omfatter en faktor VIIA og en faktor XIII

Country Status (17)

Country Link
US (3) US20030092627A1 (es)
EP (3) EP1282438B1 (es)
JP (2) JP2003532684A (es)
CN (1) CN1304049C (es)
AT (2) ATE300953T1 (es)
AU (3) AU2001258230A1 (es)
BR (1) BR0110659A (es)
CA (1) CA2406583A1 (es)
CZ (1) CZ20023667A3 (es)
DE (2) DE60112429T2 (es)
DK (1) DK1282438T3 (es)
ES (2) ES2247106T3 (es)
HU (1) HUP0301868A3 (es)
IL (1) IL152554A0 (es)
NO (1) NO20025355L (es)
PL (1) PL365042A1 (es)
WO (2) WO2001085199A1 (es)

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HUP0301246A3 (en) 2000-09-13 2005-12-28 Novo Nordisk Healthcare Ag Human coagulation factor vii variants
RU2326126C2 (ru) 2000-09-13 2008-06-10 Ново Нордиск Хелт Кэр Аг Полипептид фактора vii свертывания крови, его получение и применение
CA2427535A1 (en) * 2000-11-03 2002-05-10 Zymogenetics, Inc. Use of blood coagulation factor xiii for treating haemophilia a
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DE60129599T2 (de) * 2000-11-10 2008-04-17 Zymogenetics, Inc., Seattle Faktor xiii in kombination mit faktor ix zur behandlung von hämophilie b
EP1359935A1 (en) * 2001-02-05 2003-11-12 Novo Nordisk Health Care AG Combined use of factor vii polypeptides and factor ix polypeptides
CA2438761A1 (en) * 2001-02-21 2002-09-06 Zymogenetics, Inc. Method for treating von willebrand's disease
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US6960657B2 (en) 2001-11-02 2005-11-01 Novo Nordisk Healthcare A/G Human coagulation factor VII polypeptides
WO2003039581A1 (en) * 2001-11-09 2003-05-15 Novo Nordisk Health Care Ag Pharmaceutical composition comprising factor vii polypeptides and tranexamic acid
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RU2357751C2 (ru) 2001-12-21 2009-06-10 Ново Нордиск Хелт Кэр Аг Жидкая композиция полипептидов фактора vii
KR101006070B1 (ko) * 2001-12-21 2011-01-06 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ⅶ 폴리펩티드의 액체 조성물
BRPI0311959B8 (pt) 2002-06-21 2021-05-25 Novo Nordisk Healthcare Ag composição, métodos para preparar um polipeptídeo estável do fator vii, e para tratar uma síndrome responsiva do fator vii, e, uso do polipeptídeo do fator vii
US6911323B2 (en) 2002-09-25 2005-06-28 Novo Nordisk Healthcare A/G Human coagulation factor VII polypeptides
DK1599222T3 (da) 2003-01-08 2009-04-27 Novartis Vaccines & Diagnostic Stabiliserede vandige pr parater omfattende v vsfaktorvej-inhibitor (TFPI) eller v vsfaktorvej-inhibitorvariant
WO2004112828A1 (en) 2003-06-25 2004-12-29 Novo Nordisk Health Care Ag Liquid composition of factor vii polypeptides
AU2004264282B2 (en) 2003-08-14 2010-10-14 Novo Nordisk Health Care Ag Liquid, aqueous pharmaceutical composition of Factor VII polypeptides
EP2392655A3 (en) 2003-09-09 2012-02-29 Novo Nordisk Health Care AG Coagulation factor VII polypeptides
US20090053193A1 (en) * 2004-05-11 2009-02-26 Novo Nordisk Healthcare A/G Use of Factor VIIa for the Treatment of Burn Trauma
WO2005115442A1 (en) * 2004-05-25 2005-12-08 Novo Nordisk Health Care Ag Use of coagulation factor xiii for treatment of post surgical bleedings
CN101010333B (zh) * 2004-08-27 2013-08-14 诺和诺德医疗保健公司 从生物材料中纯化凝血因子xⅲ多肽
AU2005282065B2 (en) * 2004-09-10 2013-02-07 Pharmaorigin Aps Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis
ATE540974T1 (de) 2004-11-23 2012-01-15 Zymogenetics Inc Reinigung des rekombinanten menschlichen faktors xiii
EP1855712A2 (en) * 2005-02-28 2007-11-21 Novo Nordisk Health Care AG Fxiii variants with improved properties
EP1919499A2 (en) * 2005-07-29 2008-05-14 Universiteit van Maastricht Regulation of tissue factor activity by protein s and tissue factor pathway inhibitor
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WO2008009635A2 (en) * 2006-07-17 2008-01-24 Novo Nordisk Health Care Ag Factor viia analogues with increased activity for treating thrombocytopenia
EP2481797A1 (en) * 2007-04-13 2012-08-01 Catalyst Biosciences, Inc. Modified factor VII polypeptides and uses thereof
TWI465247B (zh) 2008-04-11 2014-12-21 Catalyst Biosciences Inc 經修飾的因子ｖｉｉ多肽和其用途
US10391062B2 (en) 2008-04-21 2019-08-27 Novo Nordisk Healthcare Ag Dry transglutaminase composition
EP2149603A1 (en) 2008-07-28 2010-02-03 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Factor IX variants with clotting activity in absence of their cofactor and their use for treating bleeding disorders
UA112050C2 (uk) * 2008-08-04 2016-07-25 БАЄР ХЕЛСКЕР ЛЛСі Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
CA2747721C (en) 2008-12-19 2021-07-20 Baxter International Inc. Tfpi inhibitors and methods of use
EP2547355B1 (en) 2010-03-19 2017-01-11 Baxalta GmbH Tfpi inhibitors and methods of use
EP2600891B1 (en) 2010-08-05 2018-01-17 Council of Scientific & Industrial Research Protein fusion constructs possessing thrombolytic and anticoagulant properties
EP2827883B1 (en) 2012-03-21 2019-05-08 Baxalta GmbH Tfpi inhibitors and methods of use
EP2881463A1 (en) 2013-12-09 2015-06-10 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Factor IX variants with clotting activity in absence of their cofactor and/or with increased F.IX clotting activity and their use for treating bleeding disorders
JP6559188B2 (ja) * 2017-07-06 2019-08-14 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
JP2018038398A (ja) * 2017-09-04 2018-03-15 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
JP2018108089A (ja) * 2018-02-19 2018-07-12 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
CN112424593A (zh) * 2018-07-25 2021-02-26 索尼公司 凝血系统分析装置
JP6848016B2 (ja) * 2019-07-16 2021-03-24 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 組織因子経路インヒビター（ｔｆｐｉ）に対するモノクローナル抗体
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US7291587B2 (en) * 2001-11-09 2007-11-06 Novo Nordisk Healthcare A/G Pharmaceutical composition comprising factor VII polypeptides and TAFI polypeptides
US7078479B2 (en) * 2001-11-09 2006-07-18 Novo Nordisk Healthcare A/G Pharmaceutical composition comprising factor VII polypeptides and alpha2-antiplasmin polypeptides
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Also Published As

Publication number Publication date
ATE311198T1 (de) 2005-12-15
DE60112429D1 (de) 2005-09-08
DE60112429T2 (de) 2006-06-01
DK1282438T3 (da) 2005-11-14
NO20025355D0 (no) 2002-11-08
CZ20023667A3 (cs) 2003-04-16
CN1304049C (zh) 2007-03-14
AU2001258230A1 (en) 2001-11-20
HUP0301868A3 (en) 2006-11-28
CN1429117A (zh) 2003-07-09
EP1282438B1 (en) 2005-08-03
AU5822801A (en) 2001-11-20
JP2004505016A (ja) 2004-02-19
WO2001085198A1 (en) 2001-11-15
DE60115422T2 (de) 2006-08-17
PL365042A1 (en) 2004-12-27
US20030092627A1 (en) 2003-05-15
EP1593389A1 (en) 2005-11-09
CA2406583A1 (en) 2001-11-15
EP1282439B1 (en) 2005-11-30
EP1282438A1 (en) 2003-02-12
US20070280920A1 (en) 2007-12-06
IL152554A0 (en) 2003-05-29
HUP0301868A2 (hu) 2003-08-28
US20060199766A1 (en) 2006-09-07
BR0110659A (pt) 2003-02-11
DE60115422D1 (de) 2006-01-05
ATE300953T1 (de) 2005-08-15
ES2247106T3 (es) 2006-03-01
EP1282439A1 (en) 2003-02-12
AU2001258228B2 (en) 2006-01-12
WO2001085199A1 (en) 2001-11-15
JP2003532684A (ja) 2003-11-05
ES2254414T3 (es) 2006-06-16

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