ATE540974T1 - Reinigung des rekombinanten menschlichen faktors xiii - Google Patents

Reinigung des rekombinanten menschlichen faktors xiii

Info

Publication number
ATE540974T1
ATE540974T1 AT05815706T AT05815706T ATE540974T1 AT E540974 T1 ATE540974 T1 AT E540974T1 AT 05815706 T AT05815706 T AT 05815706T AT 05815706 T AT05815706 T AT 05815706T AT E540974 T1 ATE540974 T1 AT E540974T1
Authority
AT
Austria
Prior art keywords
factor xiii
less
methods
affinity chromatography
purification
Prior art date
Application number
AT05815706T
Other languages
English (en)
Inventor
Carol Jewell
Hardarshan Cheema
Deborah Hogg
Wenmao Meng
Ray O'donnell
Ewan Robertson
Andrew Topping
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ATE540974T1 publication Critical patent/ATE540974T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT05815706T 2004-11-23 2005-11-23 Reinigung des rekombinanten menschlichen faktors xiii ATE540974T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63061404P 2004-11-23 2004-11-23
PCT/EP2005/056169 WO2006056575A1 (en) 2004-11-23 2005-11-23 Purification of recombinant human factor xiii

Publications (1)

Publication Number Publication Date
ATE540974T1 true ATE540974T1 (de) 2012-01-15

Family

ID=35717653

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05815706T ATE540974T1 (de) 2004-11-23 2005-11-23 Reinigung des rekombinanten menschlichen faktors xiii

Country Status (9)

Country Link
US (1) US8461302B2 (de)
EP (1) EP1817339B1 (de)
JP (1) JP5086093B2 (de)
AT (1) ATE540974T1 (de)
AU (1) AU2005308830B2 (de)
CA (1) CA2587139C (de)
ES (1) ES2378777T3 (de)
IL (1) IL182830A (de)
WO (1) WO2006056575A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2743346A1 (de) * 2012-12-11 2014-06-18 Zedira GmbH Kristallstruktur des Blutgerinnungsfaktors XIIIa
CN110314414B (zh) * 2019-07-23 2021-10-19 宝锐生物科技泰州有限公司 凝血因子xiii的分离纯化方法及其应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904751A (en) 1970-12-22 1975-09-09 Behringwerke Ag Process for isolating a fibrin stabilizing factor from human placenta
US3931399A (en) 1970-12-22 1976-01-06 Behringwerke Aktiengesellschaft Process for isolating a fibrin-stabilizing factor
US4265233A (en) * 1978-04-12 1981-05-05 Unitika Ltd. Material for wound healing
AT359653B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
AT359652B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
AT369990B (de) 1981-07-28 1983-02-25 Immuno Ag Verfahren zur herstellung eines gewebeklebstoffes
DE3419581A1 (de) * 1984-05-25 1985-11-28 Behringwerke Ag, 3550 Marburg Verfahren zur gewinnung einer faktor xiii-praeparation sowie ihre verwendung
DE3621371A1 (de) 1986-03-12 1987-09-17 Behringwerke Ag Gentechnische herstellung von faktor xiiia
ATE121776T1 (de) 1986-09-19 1995-05-15 Zymogenetics Inc Expression des biologisch aktiven faktors xiii.
JPS63196520A (ja) 1987-02-09 1988-08-15 Hoechst Japan Kk 潰瘍性大腸炎治療剤
JPH01216939A (ja) * 1988-02-24 1989-08-30 Hoechst Japan Kk 末熟児頭蓋内出血阻止剤
US5612456A (en) 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
US5204447A (en) 1988-11-14 1993-04-20 Zymogenetics, Inc. Purification of factor xiii
JPH02247199A (ja) 1989-03-17 1990-10-02 Green Cross Corp:The ヒト血液凝固第ｘ３因子の製造法
WO1991014780A1 (en) 1990-03-21 1991-10-03 Board Of Regents, The University Of Texas System Yeast expression vectors
AU2478292A (en) 1991-08-07 1993-03-02 Zymogenetics Inc. Purification of factor xiii
JPH07502734A (ja) * 1991-12-31 1995-03-23 ザイモジェネティクス，インコーポレイティド 血液損失を減少する方法および組成物
JP3195439B2 (ja) * 1992-09-28 2001-08-06 森永製菓株式会社 第ｘｉｉｉ因子の精製方法
EP1282438B1 (de) 2000-05-10 2005-08-03 Novo Nordisk Health Care AG Verwendung von faktor vii-a und faktor xiii enthaltenden pharmazeutischen verbindungen
US20040014657A1 (en) * 2001-11-05 2004-01-22 Jan Ohrstrom Use of blood coagulation factor XIII for treating haemophilia A
CA2427535A1 (en) 2000-11-03 2002-05-10 Zymogenetics, Inc. Use of blood coagulation factor xiii for treating haemophilia a
DE60129599T2 (de) 2000-11-10 2008-04-17 Zymogenetics, Inc., Seattle Faktor xiii in kombination mit faktor ix zur behandlung von hämophilie b
US20040033947A1 (en) * 2001-11-08 2004-02-19 Jan Ohrstrom Method for treating hemophilia b
US7008926B2 (en) * 2001-02-22 2006-03-07 Zymogenetics Inc. Blood coagulation factor XIII for treating platelet disorders
GB0216001D0 (en) 2002-07-10 2002-08-21 Nat Blood Authority Process and composition
JP2004123566A (ja) 2002-09-30 2004-04-22 Nihon Pharmaceutical Co Ltd ヒト血漿由来血液凝固第ｘｉｉｉ因子製剤およびその製造方法
CU23475A1 (es) * 2004-07-08 2009-12-17 Ct Ingenieria Genetica Biotech Composición farmacéutica conteniendo fragmentos polipeptídicos de serralisinas
CN101010333B (zh) * 2004-08-27 2013-08-14 诺和诺德医疗保健公司 从生物材料中纯化凝血因子xⅲ多肽

Also Published As

Publication number Publication date
JP5086093B2 (ja) 2012-11-28
ES2378777T3 (es) 2012-04-17
US8461302B2 (en) 2013-06-11
AU2005308830A1 (en) 2006-06-01
CA2587139C (en) 2014-05-27
CA2587139A1 (en) 2006-06-01
WO2006056575A1 (en) 2006-06-01
AU2005308830B2 (en) 2012-01-19
JP2008520220A (ja) 2008-06-19
EP1817339A1 (de) 2007-08-15
IL182830A (en) 2013-12-31
US20080281080A1 (en) 2008-11-13
IL182830A0 (en) 2007-08-19
EP1817339B1 (de) 2012-01-11

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