NO20030145L - Trombin-inhibitorer inneholdende en aminoisokinolingruppe - Google Patents

Trombin-inhibitorer inneholdende en aminoisokinolingruppe

Info

Publication number: NO20030145L
Authority: NO; Norway
Prior art keywords: thrombin inhibitors; inhibitors containing; aminoisoquinoline; group; aminoisoquinoline group
Prior art date: 2000-07-12

Application number

NO20030145A

Other languages

English (en)

Other versions

NO20030145D0 (no

Inventor

Johannes Bernardus Ma Rewinkel

Cornelis Marius Timmers

Paolo Giovanni Martino Conti

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-12

Filing date

2003-01-10

Publication date

2003-01-10

2003-01-10 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2003-01-10 Publication of NO20030145L publication Critical patent/NO20030145L/no

2003-01-10 Publication of NO20030145D0 publication Critical patent/NO20030145D0/no

Links

229940122388 Thrombin inhibitor Drugs 0.000 title 1
OSILBMSORKFRTB-UHFFFAOYSA-N isoquinolin-1-amine Chemical group C1=CC=C2C(N)=NC=CC2=C1 OSILBMSORKFRTB-UHFFFAOYSA-N 0.000 title 1
239000003868 thrombin inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)

NO20030145A 2000-07-12 2003-01-10 Trombin-inhibitorer inneholdende en aminoisokinolingruppe NO20030145D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00202491		2000-07-12
PCT/EP2001/007887 WO2002004423A1 (en)	2000-07-12	2001-07-09	Thrombin inhibitors comprising an aminoisoquinoline group

Publications (2)

Publication Number	Publication Date
NO20030145L true NO20030145L (no)	2003-01-10
NO20030145D0 NO20030145D0 (no)	2003-01-10

Family

ID=8171793

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20030145A NO20030145D0 (no)	2000-07-12	2003-01-10	Trombin-inhibitorer inneholdende en aminoisokinolingruppe

Country Status (23)

Country	Link
US (1)	US6642253B2 (no)
EP (1)	EP1303491A1 (no)
JP (1)	JP2004502759A (no)
KR (1)	KR20030022270A (no)
CN (1)	CN1441784A (no)
AR (1)	AR029596A1 (no)
AU (1)	AU2001278476A1 (no)
BR (1)	BR0112338A (no)
CA (1)	CA2413035A1 (no)
CZ (1)	CZ200392A3 (no)
EC (1)	ECSP034422A (no)
HR (1)	HRP20030017A2 (no)
HU (1)	HUP0301258A2 (no)
IL (1)	IL153611A0 (no)
MX (1)	MXPA03000337A (no)
NO (1)	NO20030145D0 (no)
NZ (1)	NZ523553A (no)
PE (1)	PE20020209A1 (no)
PL (1)	PL359787A1 (no)
RU (1)	RU2003104017A (no)
SK (1)	SK322003A3 (no)
WO (1)	WO2002004423A1 (no)
ZA (1)	ZA200300080B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP0400651A2 (hu)	2000-11-07	2004-06-28	Bristol-Myers Squibb Company	Szerin proteáz inhibitorokként alkalmazható savszármazékok és ezeket tartalmazó gyógyszerkészítmények
US6906192B2 (en)	2000-11-07	2005-06-14	Bristol Myers Squibb Company	Processes for the preparation of acid derivatives useful as serine protease inhibitors
TWI389899B (zh) *	2006-08-08	2013-03-21	Msd Oss Bv	具口服活性之凝血酶抑制劑
RU2468011C2 (ru) *	2006-12-27	2012-11-27	Санофи-Авентис	Замещенные циклоалкиламином производные изохинолина и изохинолинона
US7927378B2 (en) *	2007-03-05	2011-04-19	Scussel Sbj Systems, Llc	Vacuum assisted prosthetic sleeve and socket
CN109810174B (zh) *	2017-11-21	2021-01-01	首都医科大学	异喹啉-3-甲酰-TARGD(aa)aa,其制备,抗静脉血栓活性和应用
CN109810172B (zh) *	2017-11-21	2021-01-01	首都医科大学	异喹啉-3-甲酰-PARGD(aa)aa,其制备,抗静脉血栓活性和应用
CN109810173B (zh) *	2017-11-21	2020-11-27	首都医科大学	二氢异喹啉-3-甲酰-TARGD(aa)aa,其制备,抗静脉血栓活性和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL123986A (en)	1997-04-24	2011-10-31	Organon Nv	Medicinal compounds

2001
- 2001-07-09 RU RU2003104017/04A patent/RU2003104017A/ru not_active Application Discontinuation
- 2001-07-09 KR KR10-2003-7000363A patent/KR20030022270A/ko not_active Withdrawn
- 2001-07-09 EP EP01956519A patent/EP1303491A1/en not_active Withdrawn
- 2001-07-09 SK SK32-2003A patent/SK322003A3/sk not_active Application Discontinuation
- 2001-07-09 MX MXPA03000337A patent/MXPA03000337A/es unknown
- 2001-07-09 HR HR20030017A patent/HRP20030017A2/hr not_active Application Discontinuation
- 2001-07-09 CZ CZ200392A patent/CZ200392A3/cs unknown
- 2001-07-09 IL IL15361101A patent/IL153611A0/xx unknown
- 2001-07-09 CA CA002413035A patent/CA2413035A1/en not_active Abandoned
- 2001-07-09 CN CN01812607A patent/CN1441784A/zh active Pending
- 2001-07-09 PL PL35978701A patent/PL359787A1/xx not_active Application Discontinuation
- 2001-07-09 AU AU2001278476A patent/AU2001278476A1/en not_active Abandoned
- 2001-07-09 JP JP2002509290A patent/JP2004502759A/ja not_active Withdrawn
- 2001-07-09 NZ NZ523553A patent/NZ523553A/en unknown
- 2001-07-09 WO PCT/EP2001/007887 patent/WO2002004423A1/en not_active Ceased
- 2001-07-09 HU HU0301258A patent/HUP0301258A2/hu unknown
- 2001-07-09 US US10/332,792 patent/US6642253B2/en not_active Expired - Fee Related
- 2001-07-09 BR BR0112338-6A patent/BR0112338A/pt not_active IP Right Cessation
- 2001-07-10 PE PE2001000684A patent/PE20020209A1/es not_active Application Discontinuation
- 2001-07-11 AR ARP010103283A patent/AR029596A1/es not_active Application Discontinuation
2003
- 2003-01-03 ZA ZA200300080A patent/ZA200300080B/en unknown
- 2003-01-10 NO NO20030145A patent/NO20030145D0/no not_active Application Discontinuation
- 2003-01-10 EC EC2003004422A patent/ECSP034422A/es unknown

Also Published As

Publication number	Publication date
IL153611A0 (en)	2003-07-06
RU2003104017A (ru)	2004-08-20
HUP0301258A2 (hu)	2003-08-28
JP2004502759A (ja)	2004-01-29
NZ523553A (en)	2004-04-30
PL359787A1 (en)	2004-09-06
KR20030022270A (ko)	2003-03-15
AU2001278476A1 (en)	2002-01-21
WO2002004423A9 (en)	2003-05-15
HRP20030017A2 (en)	2003-04-30
ECSP034422A (es)	2003-03-10
WO2002004423A8 (en)	2003-03-06
BR0112338A (pt)	2003-07-22
CA2413035A1 (en)	2002-01-17
CZ200392A3 (cs)	2003-05-14
ZA200300080B (en)	2004-04-05
NO20030145D0 (no)	2003-01-10
WO2002004423A1 (en)	2002-01-17
SK322003A3 (en)	2003-06-03
AR029596A1 (es)	2003-07-02
CN1441784A (zh)	2003-09-10
EP1303491A1 (en)	2003-04-23
PE20020209A1 (es)	2002-03-19
MXPA03000337A (es)	2004-04-05
US6642253B2 (en)	2003-11-04
US20030166579A1 (en)	2003-09-04

Legal Events

Date	Code	Title	Description
2006-02-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
DK1294714T3 (da)	2007-12-03	Trombinreceptorantagonister
CY2012007I1 (el)	2014-07-02	Πεπτιδομιμητικοι αναστολεις πρωτεασης
DE60002193D1 (de)	2003-05-22	Metalloprotease inhibitoren
DE60211317D1 (de)	2006-06-14	Rho-kinase inhibitoren
DE60218138D1 (de)	2007-03-29	Rho-kinase inhibitoren
NO20012980D0 (no)	2001-06-15	Proteaseinhibitorer
ATE524441T1 (de)	2011-09-15	Vla-4-inhibitoren
NO20024997D0 (no)	2002-10-17	2-guanidino-4-arylkinazoliner som NHE-3-inhibitorer
DK1272488T3 (da)	2006-07-17	Tri-aryl-substitueret ethan-PDE4-inhibitorer
NO20014243L (no)	2001-10-17	Dihetero-substituerte metalloproteaseinhibitorer
NO20003814D0 (no)	2000-07-25	Trombininhibitorer
NO20014875D0 (no)	2001-10-08	Promedikamenter for trombin inhibitorer
NO20032807L (no)	2003-08-15	Substituerte 8-arylkinolin-fosfodiesterase-4-inhibitorer
DE50100446D1 (de)	2003-09-11	Haftklebstoffe
ATE252547T1 (de)	2003-11-15	Matrixmetalloproteinaseinhibitoren
NO20025786L (no)	2003-02-12	Protaseinhibitorer
PT1339695E (pt)	2006-08-31	Inibidores da farnesiltransferase
NO20030145L (no)	2003-01-10	Trombin-inhibitorer inneholdende en aminoisokinolingruppe
DE10196444T1 (de)	2003-10-02	Prüfvorrichtung
DE69903319D1 (de)	2002-11-07	Fkbp inhibitoren
NO20025005D0 (no)	2002-10-17	Proteaseinhibitorer
EP1463521A4 (en)	2009-06-24	INHIBITOR OF GP41
AR028075A1 (es)	2003-04-23	Inhibidores de la peptido-desformilasa
DE60132468D1 (de)	2008-03-06	Alen-lanosterol zyklase inhibitoren
NO20032328L (no)	2003-07-02	Proteaseinhibitorer