NO20030604L - Anvendelse av perfluoralkylholdige metallkomplekser som kontrastmiddel vedMR-avbildning for å påvise plakk, tumorer og nekroser - Google Patents

Anvendelse av perfluoralkylholdige metallkomplekser som kontrastmiddel vedMR-avbildning for å påvise plakk, tumorer og nekroser

Info

Publication number
NO20030604L
NO20030604L NO20030604A NO20030604A NO20030604L NO 20030604 L NO20030604 L NO 20030604L NO 20030604 A NO20030604 A NO 20030604A NO 20030604 A NO20030604 A NO 20030604A NO 20030604 L NO20030604 L NO 20030604L
Authority
NO
Norway
Prior art keywords
perfluoroalkyl
necrosis
tumors
imaging
contrast agent
Prior art date
Application number
NO20030604A
Other languages
English (en)
Norwegian (no)
Other versions
NO20030604D0 (no
Inventor
Johannes Platzek
Peter Mareski
Ulrich Niedballa
Bernd Raduechel
Hanns-Joachim Weinmann
Bernd Misselwitz
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10040380A external-priority patent/DE10040380B4/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20030604D0 publication Critical patent/NO20030604D0/no
Publication of NO20030604L publication Critical patent/NO20030604L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20030604A 2000-08-11 2003-02-07 Anvendelse av perfluoralkylholdige metallkomplekser som kontrastmiddel vedMR-avbildning for å påvise plakk, tumorer og nekroser NO20030604L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10040380A DE10040380B4 (de) 2000-08-11 2000-08-11 Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques
PCT/EP2001/008498 WO2002013874A2 (de) 2000-08-11 2001-07-23 Verwendung von perfluoralkylhaltigen metallkomplexen als kontrastmittel im mr-imaging zur darstellung von plaques, tumoren und nekrosen

Publications (2)

Publication Number Publication Date
NO20030604D0 NO20030604D0 (no) 2003-02-07
NO20030604L true NO20030604L (no) 2003-04-11

Family

ID=7652860

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030604A NO20030604L (no) 2000-08-11 2003-02-07 Anvendelse av perfluoralkylholdige metallkomplekser som kontrastmiddel vedMR-avbildning for å påvise plakk, tumorer og nekroser

Country Status (26)

Country Link
EP (1) EP1307236A2 (et)
JP (1) JP2004506025A (et)
KR (1) KR20030022387A (et)
CN (1) CN1469757A (et)
AR (1) AR034139A1 (et)
AU (2) AU2001277549B2 (et)
BG (1) BG107542A (et)
BR (1) BR0113188A (et)
CA (1) CA2419223A1 (et)
CZ (1) CZ2003392A3 (et)
DE (1) DE10066210B4 (et)
EE (1) EE200300061A (et)
HR (1) HRP20030173A2 (et)
HU (1) HUP0300736A3 (et)
IL (1) IL154385A0 (et)
MX (1) MXPA03001287A (et)
NO (1) NO20030604L (et)
NZ (1) NZ523932A (et)
PL (1) PL365596A1 (et)
RU (1) RU2290206C2 (et)
SK (1) SK1572003A3 (et)
TW (1) TWI296931B (et)
UA (1) UA82642C2 (et)
WO (1) WO2002013874A2 (et)
YU (1) YU10603A (et)
ZA (1) ZA200301949B (et)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10231799B4 (de) * 2002-07-10 2006-10-05 Schering Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Intravasalen Thromben
US7344704B2 (en) 2002-07-10 2008-03-18 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi
DE102005008309A1 (de) * 2005-02-17 2006-08-24 Schering Ag Pharmazeutische Mittel enthaltend fluoralkylhaltige Metallkomplexe und Epothilone
DE102006021495A1 (de) * 2006-05-09 2007-11-15 Bayer Schering Pharma Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel zur Diagnose der Alzheimer Krankheit
US7887835B2 (en) * 2006-09-19 2011-02-15 Fujifilm Corporation Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound
DE102006049821A1 (de) 2006-10-18 2008-04-24 Bayer Schering Pharma Aktiengesellschaft Metallchelate mit perfluoriertem PEG-Rest, Verfahren zu deren Herstellung, sowie deren Verwendung
DE102007015598A1 (de) * 2007-03-29 2008-10-02 Heinrich-Heine-Universität Düsseldorf Verwendung von fluorhaltigen Verbindungen zu Diagnosezwecken mit Hilfe bildgebender Verfahren
JP2011190183A (ja) * 2010-03-11 2011-09-29 Noguchi Institute フルオラス化糖結合型クラウンエーテル誘導体
US9976072B2 (en) * 2014-03-26 2018-05-22 Chevron U.S.A. Inc. Multicarboxylate compositions and method of making the same
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
US11104639B2 (en) 2016-09-14 2021-08-31 Daikin Industries, Ltd. Branched fluorine-containing compound
EP3544964B1 (en) 2016-11-28 2020-06-17 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
IL321215B2 (en) 2018-11-23 2026-05-01 Bayer Ag Contrast media formulation and process for its preparation
CN109867635A (zh) * 2019-02-14 2019-06-11 华东师范大学 一种t1型胶束磁共振成像造影剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009856A1 (en) * 1993-10-01 1995-04-13 The Regents Of The University Of California Boronated metalloporphyrins and therapeutic methods
US5502094A (en) * 1994-05-20 1996-03-26 Minnesota Mining And Manufacturing Company Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use
DE19603033A1 (de) * 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
JPH10112939A (ja) * 1996-10-07 1998-04-28 Nec Corp 電源切替回路
DE19729013A1 (de) * 1997-07-03 1999-02-04 Schering Ag Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
US6019959A (en) * 1997-07-31 2000-02-01 Schering Aktiengesellschaft Oligomeric compounds that contain perfluoroalkyl, process for their production, and their use in NMR diagnosis

Also Published As

Publication number Publication date
HUP0300736A3 (en) 2010-01-28
CA2419223A1 (en) 2003-02-11
MXPA03001287A (es) 2003-10-06
PL365596A1 (en) 2005-01-10
ZA200301949B (en) 2004-12-14
BR0113188A (pt) 2003-06-24
CN1469757A (zh) 2004-01-21
EP1307236A2 (de) 2003-05-07
WO2002013874A2 (de) 2002-02-21
IL154385A0 (en) 2003-09-17
RU2290206C2 (ru) 2006-12-27
DE10066210B4 (de) 2008-02-28
YU10603A (sh) 2006-05-25
JP2004506025A (ja) 2004-02-26
BG107542A (bg) 2003-09-30
UA82642C2 (uk) 2008-05-12
AR034139A1 (es) 2004-02-04
HRP20030173A2 (en) 2005-04-30
HUP0300736A2 (hu) 2003-09-29
CZ2003392A3 (cs) 2003-09-17
AU2001277549B2 (en) 2007-02-08
SK1572003A3 (en) 2003-10-07
KR20030022387A (ko) 2003-03-15
NZ523932A (en) 2007-07-27
NO20030604D0 (no) 2003-02-07
WO2002013874A8 (de) 2002-06-13
EE200300061A (et) 2004-12-15
AU7754901A (en) 2002-02-25
TWI296931B (en) 2008-05-21

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