NO20031030L - Nye krystaller av N-hydroksy-2(S)-metyl-5-etoksymetoksy-4(S)- [N-(4-fenoksyfenylkarbonyl)amino]pentanamid, fremgangsmåte for deresfremstilling og medisinerinneholdende krystallene som den aktive bestanddel - Google Patents

Nye krystaller av N-hydroksy-2(S)-metyl-5-etoksymetoksy-4(S)- [N-(4-fenoksyfenylkarbonyl)amino]pentanamid, fremgangsmåte for deresfremstilling og medisinerinneholdende krystallene som den aktive bestanddel

Info

Publication number: NO20031030L
Authority: NO; Norway
Prior art keywords: crystals; phenoxyphenylcarbonyl; ethoxymethoxy; pentanamide; hydroxy
Prior art date: 2000-09-08

Application number

NO20031030A

Other languages

English (en)

Other versions

NO20031030D0 (no

Inventor

Shigehiro Okuyama

Masaki Okamoto

Original Assignee

Ono Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-08

Filing date

2003-03-05

Publication date

2003-05-08

2003-03-05 Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co

2003-03-05 Publication of NO20031030D0 publication Critical patent/NO20031030D0/no

2003-05-08 Publication of NO20031030L publication Critical patent/NO20031030L/no

Links

239000013078 crystal Substances 0.000 title 2
239000004480 active ingredient Substances 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
HDWWQELUBWGQGA-WMZOPIPTSA-N n-[(2s,4s)-1-(ethoxymethoxy)-5-(hydroxyamino)-4-methyl-5-oxopentan-2-yl]-4-phenoxybenzamide Chemical compound C1=CC(C(=O)N[C@@H](C[C@H](C)C(=O)NO)COCOCC)=CC=C1OC1=CC=CC=C1 HDWWQELUBWGQGA-WMZOPIPTSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Reproductive Health (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Transplantation (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Vascular Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20031030A 2000-09-08 2003-03-05 Nye krystaller av N-hydroksy-2(S)-metyl-5-etoksymetoksy-4(S)- [N-(4-fenoksyfenylkarbonyl)amino]pentanamid, fremgangsmåte for deresfremstilling og medisinerinneholdende krystallene som den aktive bestanddel NO20031030L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2000273445		2000-09-08
PCT/JP2001/007775 WO2002020467A1 (fr)	2000-09-08	2001-09-07	Nouveaux cristaux de n-hydroxy-2(s)-methyl-5-ethoxymethoxy-4(s)-[n-(4-phenoxyphenylcarbonyl)amino]pentanamide, leur procede de production et medicaments contenant ces cristaux en tant que substance active

Publications (2)

Publication Number	Publication Date
NO20031030D0 NO20031030D0 (no)	2003-03-05
NO20031030L true NO20031030L (no)	2003-05-08

Family

ID=18759384

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20031030A NO20031030L (no)	2000-09-08	2003-03-05	Nye krystaller av N-hydroksy-2(S)-metyl-5-etoksymetoksy-4(S)- [N-(4-fenoksyfenylkarbonyl)amino]pentanamid, fremgangsmåte for deresfremstilling og medisinerinneholdende krystallene som den aktive bestanddel

Country Status (16)

Country	Link
US (1)	US20040152785A1 (no)
EP (1)	EP1316547A4 (no)
KR (1)	KR20030059125A (no)
CN (1)	CN1473148A (no)
AU (1)	AU2001284477A1 (no)
BR (1)	BR0113760A (no)
CA (1)	CA2419744A1 (no)
CZ (1)	CZ2003636A3 (no)
HU (1)	HUP0302928A3 (no)
IL (1)	IL154625A0 (no)
MX (1)	MXPA03001985A (no)
NO (1)	NO20031030L (no)
PL (1)	PL361702A1 (no)
RU (1)	RU2003106391A (no)
WO (1)	WO2002020467A1 (no)
ZA (1)	ZA200301869B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0100761D0 (en)	2001-01-11	2001-02-21	Biocompatibles Ltd	Drug delivery from stents
WO2005040098A1 (en) *	2003-10-21	2005-05-06	Warner-Lambert Company Llc	Polymorphic form of n-[(r)-2,3-dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-benzamide
US7713541B1 (en) *	2006-11-21	2010-05-11	Abbott Cardiovascular Systems Inc.	Zwitterionic terpolymers, method of making and use on medical devices

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1024134A4 (en) *	1997-10-09	2003-05-14	Ono Pharmaceutical Co	DERIVATIVES OF AMINOBUTANIC ACID

2001
- 2001-09-07 HU HU0302928A patent/HUP0302928A3/hu unknown
- 2001-09-07 EP EP01963509A patent/EP1316547A4/en not_active Withdrawn
- 2001-09-07 MX MXPA03001985A patent/MXPA03001985A/es not_active Application Discontinuation
- 2001-09-07 WO PCT/JP2001/007775 patent/WO2002020467A1/ja not_active Ceased
- 2001-09-07 CA CA002419744A patent/CA2419744A1/en not_active Abandoned
- 2001-09-07 KR KR10-2003-7003266A patent/KR20030059125A/ko not_active Withdrawn
- 2001-09-07 BR BR0113760-3A patent/BR0113760A/pt not_active Application Discontinuation
- 2001-09-07 AU AU2001284477A patent/AU2001284477A1/en not_active Abandoned
- 2001-09-07 CN CNA018185525A patent/CN1473148A/zh active Pending
- 2001-09-07 US US10/362,290 patent/US20040152785A1/en not_active Abandoned
- 2001-09-07 IL IL15462501A patent/IL154625A0/xx unknown
- 2001-09-07 CZ CZ2003636A patent/CZ2003636A3/cs unknown
- 2001-09-07 PL PL01361702A patent/PL361702A1/xx unknown
- 2001-09-07 RU RU2003106391/04A patent/RU2003106391A/ru not_active Application Discontinuation
2003
- 2003-03-05 NO NO20031030A patent/NO20031030L/no not_active Application Discontinuation
- 2003-03-06 ZA ZA200301869A patent/ZA200301869B/en unknown

Also Published As

Publication number	Publication date
HUP0302928A2 (hu)	2003-12-29
MXPA03001985A (es)	2003-09-05
US20040152785A1 (en)	2004-08-05
CA2419744A1 (en)	2003-02-26
PL361702A1 (en)	2004-10-04
IL154625A0 (en)	2003-09-17
BR0113760A (pt)	2003-07-15
AU2001284477A1 (en)	2002-03-22
RU2003106391A (ru)	2004-07-27
KR20030059125A (ko)	2003-07-07
CN1473148A (zh)	2004-02-04
EP1316547A4 (en)	2005-10-12
NO20031030D0 (no)	2003-03-05
CZ2003636A3 (cs)	2003-08-13
HUP0302928A3 (en)	2005-03-29
WO2002020467A1 (fr)	2002-03-14
EP1316547A1 (en)	2003-06-04
ZA200301869B (en)	2004-06-25

Legal Events

Date	Code	Title	Description
2005-06-20	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20040268L (no)	2004-03-23	Nye 2H-pyridazin-3-derivater, farmasoytiske preparater inneholdende slike og fremgangsmate for fremstilling av den aktive ingrediensen
NO20043702L (no)	2004-12-03	8-azaprostaglandinderivatforbindelser og legemidler inneholdende forbindelsene som den aktive bestanddel
DK1498411T3 (da)	2013-04-15	Diketohydrazinderivatforbindelser og medikamenter indeholdende forbindelserne som den aktive bestanddel
HUP0004383A2 (hu)	2001-08-28	Hatóanyagként klodronátot és vivőanyagként szilíciumozott mikrokristályos cellulózt tartalmazó gyógyszerészeti készítmény
DK1178958T3 (da)	2004-06-21	N-cyanomethylamider som proteaseinhibitorer
NO20040564L (no)	2004-05-10	Karboksylsyrederivatforbindelser og legemidler omfattende disse forbindelser som den aktive bestanddel
NO20032438L (no)	2003-07-09	Ortosubstituerte og metasubstituerte bisarylforbindelser, fremgangsmåte forfremstilling derav, deres anvendelse som et medikament samtfarmasöytiske preparater inneholdende forbindelsene
PL374443A1 (en)	2005-10-17	Novel pyrimidineamide derivatives and the use thereof
NO20040356L (no)	2004-03-19	Indaneddiksyrederivater og deres andvendelse som farmasoytiske midler, intermediater og fremgangsmate for fremstilling.
WO2003015779A3 (de)	2003-10-23	Matrixkontrolliertes transdermales therapeutisches system zur anwendung von pramipexol und ropinirol
EP1619180A4 (en)	2006-05-24	CASR ANTAGONIST
NO20006646D0 (no)	2000-12-22	Aminosyrederivater og legemidler inneholdende de samme som aktiv bestanddel
SE0102440D0 (sv)	2001-07-05	New compound
ATE253359T1 (de)	2003-11-15	Antithrombotische mittel
NO20015058D0 (no)	2001-10-18	Nye ribose-substituerte aromatiske amider, metode for fremstilling, og andvendelse derav som medikamenter
NO20031030L (no)	2003-05-08	Nye krystaller av N-hydroksy-2(S)-metyl-5-etoksymetoksy-4(S)- [N-(4-fenoksyfenylkarbonyl)amino]pentanamid, fremgangsmåte for deresfremstilling og medisinerinneholdende krystallene som den aktive bestanddel
MXPA05014143A (es)	2006-02-24	Derivados de cumarina para el tratamiento de trastornos oftalmicos.
DE60302951D1 (de)	2006-02-02	Pyroglutaminsäure-salz von Amlodipin
DE69828522D1 (de)	2005-02-10	Antithrombotische mittel
NO20034985L (no)	2003-11-10	Nye 5-tio-SS-D-xylopyranosid-derivater, fremgangsmåte for fremstilling derav, farmasöytiske blandinger inneholdende dem og den terapeutiskeanvendelse derav
NO20041878L (no)	2004-08-12	Karboksylsyrederivat-forbindelser og legemidler inneholdende de samme som den aktive bestanddel.
NO20021527L (no)	2002-05-27	Pyrimidinderivater, fremgangsmåte for fremstilling av derivatene og legemidler inneholdende de samme som den aktivebestanddel
IL152751A0 (en)	2003-06-24	Optically active 2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them
NO20001846D0 (no)	2000-04-10	Nye farmasøytisk aktive forbindelser, deres fremstilling og anvendelse som ECE-inhibitorer
NO20030474D0 (no)	2003-01-30	Demens-legemiddel som inneholder 2-aryl-8- oksodihydropurinderivater som denaktive bestanddel