NO20031532L - Pravastatin sodium, mainly free of pravastatin lactone and epi-pravastatin, and preparations containing this - Google Patents

Pravastatin sodium, mainly free of pravastatin lactone and epi-pravastatin, and preparations containing this

Info

Publication number
NO20031532L
NO20031532L NO20031532A NO20031532A NO20031532L NO 20031532 L NO20031532 L NO 20031532L NO 20031532 A NO20031532 A NO 20031532A NO 20031532 A NO20031532 A NO 20031532A NO 20031532 L NO20031532 L NO 20031532L
Authority
NO
Norway
Prior art keywords
pravastatin
epi
lactone
preparations containing
sodium
Prior art date
Application number
NO20031532A
Other languages
Norwegian (no)
Other versions
NO20031532D0 (en
Inventor
Vilmos Keri
Lajos Deak
Ilona Forgacs
Csaba Szabo
Arvai Edit Nagyne
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22897222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20031532(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of NO20031532D0 publication Critical patent/NO20031532D0/en
Publication of NO20031532L publication Critical patent/NO20031532L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20031532A 2000-10-05 2003-04-04 Pravastatin sodium, mainly free of pravastatin lactone and epi-pravastatin, and preparations containing this NO20031532L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23827800P 2000-10-05 2000-10-05
PCT/US2001/031230 WO2002030415A1 (en) 2000-10-05 2001-10-05 Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same

Publications (2)

Publication Number Publication Date
NO20031532D0 NO20031532D0 (en) 2003-04-04
NO20031532L true NO20031532L (en) 2003-04-04

Family

ID=22897222

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031532A NO20031532L (en) 2000-10-05 2003-04-04 Pravastatin sodium, mainly free of pravastatin lactone and epi-pravastatin, and preparations containing this

Country Status (18)

Country Link
EP (1) EP1330245A4 (en)
JP (6) JP3737801B2 (en)
KR (1) KR20030059173A (en)
CN (1) CN1468098A (en)
AU (1) AU2002211462A1 (en)
CA (1) CA2422744A1 (en)
CZ (1) CZ20031166A3 (en)
HR (1) HRP20030347A2 (en)
HU (1) HUP0400913A2 (en)
IL (1) IL155194A0 (en)
IS (1) IS6766A (en)
MX (1) MXPA03002963A (en)
NO (1) NO20031532L (en)
NZ (1) NZ525631A (en)
PL (1) PL361230A1 (en)
SK (1) SK5232003A3 (en)
WO (1) WO2002030415A1 (en)
ZA (1) ZA200302313B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1265604T1 (en) * 1999-11-30 2007-04-30 Sag Teva Gyogyszergyar Zartkoe Process for recovering statin compounds from a fermentation broth
EP1798214A3 (en) * 1999-11-30 2007-08-01 Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság Process for recovering statin compounds from a fermentation broth
US6444452B1 (en) * 1999-11-30 2002-09-03 Biogal Gyogyszergyar Rt. Process for recovering statin compounds from a fermentation broth
CZ20021998A3 (en) 1999-12-14 2003-02-12 Biogal Gyogyszergyar Rt. Novel forms of pravastatin sodium salt
JP3737801B2 (en) * 2000-10-05 2006-01-25 テバ ジョジセルジャール レースベニュタールシャシャーグ Pravastatin sodium substantially free of pravastatin lactone and epipravastatin, and a composition comprising the same
JP3236282B1 (en) * 2000-10-16 2001-12-10 三共株式会社 How to purify pravastatin
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
EP1452519A1 (en) * 2003-02-25 2004-09-01 Balkanpharma-Razgrad AD Method for the isolation and purification of pravastatin sodium
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (en) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd CHEMICAL COMPOUNDS
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
EP1641447B1 (en) * 2003-11-24 2008-10-29 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Method of purifying pravastatin
EP1786414A4 (en) 2004-08-06 2008-04-09 Transform Pharmaceuticals Inc Novel statin pharmaceutical compositions and related methods of treatment
ES2254028B1 (en) * 2004-11-29 2007-03-01 Ercros Industrial, S.A. PROCEDURE FOR OBTAINING PRAVASTATIN SODIUM PURIFIED.
WO2006091980A1 (en) * 2005-02-25 2006-08-31 Teva Pharmaceutical Industries Ltd. Process of purifying tadalafil
JP4813841B2 (en) * 2005-07-25 2011-11-09 キユーピー株式会社 Method for producing pravastatin sodium
HU229260B1 (en) * 2010-11-29 2013-10-28 Egis Gyogyszergyar Nyrt Process for preparation of rosuvastatin salts
CN114031496B (en) * 2021-11-30 2024-09-27 广东蓝宝制药有限公司 A method for preparing high-purity pravastatin 1,1,3,3-tetramethylbutylamine

Family Cites Families (25)

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US3378441A (en) * 1963-10-17 1968-04-16 S B Penick & Company Tetraene antibiotic purification
JPS5221594B2 (en) * 1973-09-29 1977-06-11
YU40452B (en) * 1975-02-07 1986-02-28 Beecham Group Plc Process for the elimination of contaminating impurities from clavulinic acid
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
MX7065E (en) * 1980-06-06 1987-04-10 Sankyo Co A MICROBIOLOGICAL PROCEDURE FOR PREPARING DERIVATIVES OF ML-236B
JPS572240A (en) * 1980-06-06 1982-01-07 Sankyo Co Ltd Ml-236b derivative
JPS5889191A (en) * 1981-11-20 1983-05-27 Sankyo Co Ltd Preparation of 3-hydroxy-ml-236b derivative
JPS5890509A (en) * 1981-11-25 1983-05-30 Sankyo Co Ltd Composition for remedy of hypercholesterolemia
JPH01190661A (en) * 1988-01-22 1989-07-31 Konishi Kagaku Kogyo Kk Purification of 4,4'-dihydroxydiphenylsulfone
JP2739328B2 (en) * 1988-09-14 1998-04-15 日本ケミファ株式会社 Purification method of benzimidazole compound
US5202029A (en) * 1991-03-13 1993-04-13 Caron Kabushiki Kaisha Process for purification of hmg-coa reductase inhibitors
NZ250609A (en) * 1992-12-28 1995-07-26 Sankyo Co Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
JPH06256278A (en) * 1993-03-03 1994-09-13 Nissan Chem Ind Ltd Optically active alpha-carbamoylalkanoic acid derivative and its production
CA2126365C (en) * 1993-07-06 1999-08-24 Steven W. Felman Recovery of citric acid from impure process streams by addition of strong acids and salts thereof
ES2112042T3 (en) * 1994-03-31 1998-03-16 Cultor Oy PROCEDURE FOR THE RECOVERY OF NATAMYCIN.
WO1997006128A1 (en) * 1995-08-03 1997-02-20 Gist-Brocades B.V. Selective process for the deacylation of acylated compounds
JPH09124655A (en) * 1995-11-01 1997-05-13 Sankyo Co Ltd Novel squalene synthase inhibitory compounds
EP0877089A1 (en) * 1997-05-07 1998-11-11 Gist-Brocades B.V. HMG-CoA reductase inhibitor preparation process
SI20072A (en) * 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. PROCEDURE OF PREPARATION OF INHIBITORS OF HMG-CoA REDUCTASE
SI20070A (en) * 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. NOVEL SALTS OF INHIBITORS OF HMG-CoA REDUCTASE
JP2000229855A (en) * 1998-12-07 2000-08-22 Satoshi Takebe Pravastatin sodium tablet
DE60019898T2 (en) * 1999-02-03 2006-08-10 Institute For Drug Research Ltd. MICROBIAL METHOD FOR PREPARING PRAVASTATIN
HUP9902352A1 (en) * 1999-07-12 2000-09-28 Gyógyszerkutató Intézet Kft. Process for producing pravastatin by microbiological way
US6444452B1 (en) * 1999-11-30 2002-09-03 Biogal Gyogyszergyar Rt. Process for recovering statin compounds from a fermentation broth
JP3737801B2 (en) * 2000-10-05 2006-01-25 テバ ジョジセルジャール レースベニュタールシャシャーグ Pravastatin sodium substantially free of pravastatin lactone and epipravastatin, and a composition comprising the same

Also Published As

Publication number Publication date
EP1330245A4 (en) 2004-10-20
HUP0400913A2 (en) 2006-11-28
NO20031532D0 (en) 2003-04-04
CA2422744A1 (en) 2002-04-18
IL155194A0 (en) 2003-11-23
JP2013128486A (en) 2013-07-04
PL361230A1 (en) 2004-10-04
WO2002030415A1 (en) 2002-04-18
JP2006036781A (en) 2006-02-09
JP2004510817A (en) 2004-04-08
WO2002030415A9 (en) 2002-10-31
JP3737801B2 (en) 2006-01-25
ZA200302313B (en) 2004-03-25
AU2002211462A1 (en) 2002-04-22
EP1330245A1 (en) 2003-07-30
HRP20030347A2 (en) 2005-04-30
SK5232003A3 (en) 2004-06-08
JP2015212300A (en) 2015-11-26
NZ525631A (en) 2005-05-27
CZ20031166A3 (en) 2004-04-14
IS6766A (en) 2003-04-01
CN1468098A (en) 2004-01-14
KR20030059173A (en) 2003-07-07
JP2009268479A (en) 2009-11-19
JP2005013238A (en) 2005-01-20
MXPA03002963A (en) 2005-01-25

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Legal Events

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