NO20041434L - Fremgangsmate ved fremstilling av heksahydro-furo[2,3-B]furan-3-ol - Google Patents

Fremgangsmate ved fremstilling av heksahydro-furo[2,3-B]furan-3-ol

Info

Publication number
NO20041434L
NO20041434L NO20041434A NO20041434A NO20041434L NO 20041434 L NO20041434 L NO 20041434L NO 20041434 A NO20041434 A NO 20041434A NO 20041434 A NO20041434 A NO 20041434A NO 20041434 L NO20041434 L NO 20041434L
Authority
NO
Norway
Prior art keywords
furo
furan
hexahydro
preparing
preparing hexahydro
Prior art date
Application number
NO20041434A
Other languages
English (en)
Other versions
NO328934B1 (no
Inventor
Dominique Louis Nest Surleraux
Bart Rudolf Romanie Kesteleyn
Peter Jan Leonard Quaedflieg
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8180908&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20041434(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of NO20041434L publication Critical patent/NO20041434L/no
Publication of NO328934B1 publication Critical patent/NO328934B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20041434A 2001-09-10 2004-04-06 Fremgangsmate ved fremstilling av heksahydro-furo[2,3-B]furan-3-ol NO328934B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203416 2001-09-10
PCT/EP2002/010062 WO2003022853A1 (en) 2001-09-10 2002-09-06 Method for the preparation of hexahydro-furo[2,3-b]furan-3-ol

Publications (2)

Publication Number Publication Date
NO20041434L true NO20041434L (no) 2004-06-10
NO328934B1 NO328934B1 (no) 2010-06-21

Family

ID=8180908

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20041434A NO328934B1 (no) 2001-09-10 2004-04-06 Fremgangsmate ved fremstilling av heksahydro-furo[2,3-B]furan-3-ol

Country Status (27)

Country Link
US (1) US7126015B2 (no)
EP (1) EP1448567B1 (no)
JP (1) JP4521185B2 (no)
KR (1) KR100894673B1 (no)
CN (2) CN100519561C (no)
AP (1) AP1758A (no)
AR (1) AR036501A1 (no)
AT (1) ATE453648T1 (no)
AU (1) AU2002333809C1 (no)
BR (1) BRPI0212341B8 (no)
CA (1) CA2459168C (no)
CY (1) CY1109974T1 (no)
DE (1) DE60234952D1 (no)
DK (1) DK1448567T3 (no)
EA (1) EA010883B1 (no)
ES (1) ES2338538T3 (no)
HR (1) HRP20040320B1 (no)
HU (1) HU229505B1 (no)
IL (2) IL160166A0 (no)
MX (1) MXPA04002247A (no)
NO (1) NO328934B1 (no)
NZ (1) NZ531641A (no)
PL (1) PL224030B1 (no)
PT (1) PT1448567E (no)
SI (1) SI21463B (no)
WO (1) WO2003022853A1 (no)
ZA (1) ZA200401501B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60308695T2 (de) * 2002-06-27 2007-08-16 Smithkline Beecham Corp. Herstellung von Stereoisomeren von (3Alpha,3alpha/beta,6alpha/beta) hexahydrofuro[2,3-b]furan-3-ol
EP1589018A4 (en) * 2002-12-27 2007-03-14 Sumitomo Chemical Co METHOD OF PREPARING HEXAHYDROFUROFURANOL DERIVATIVES, INTERMEDIATE PRODUCTS AND MANUFACTURING METHOD THEREFOR
JP4818124B2 (ja) 2003-12-23 2011-11-16 テイボテク・フアーマシユーチカルズ・リミテツド （３Ｒ，３ａＳ，６ａＲ）−ヘキサヒドロフロ〔２，３−ｂ〕フラン−３−イル（１Ｓ，１Ｒ）−３−〔〔（４−アミノフェニル）スルホニル〕（イソブチル）アミノ〕−１−ベンジル−２−ヒドロキシプロピルカルバマートの製造方法
TWI383975B (zh) * 2004-03-31 2013-02-01 悌柏泰克醫藥有限公司 製備（３Ｒ，３ａＳ，６ａＲ）六氫-呋喃并〔２，３-ｂ〕呋喃-３-醇之方法
JP5549898B2 (ja) * 2006-03-31 2014-07-16 独立行政法人産業技術総合研究所 ５−ヒドロキシメチル−２−フルフラールの製造法
CN102432621B (zh) * 2006-11-09 2016-02-17 爱尔兰詹森科学公司 六氢呋喃并[2,3-b]呋喃-3-醇的制备方法
CN101024646B (zh) * 2007-02-06 2010-07-14 启东东岳药业有限公司 4-甲氧基呋喃并呋喃-2-酮的纯化方法
WO2008132154A1 (en) 2007-04-27 2008-11-06 Tibotec Pharmaceuticals Ltd. Methods for the preparation of n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives
US8592487B2 (en) 2007-10-26 2013-11-26 Concert Pharmaceuticals, Inc. Deuterated darunavir
TWI482775B (zh) 2008-09-01 2015-05-01 Tibotec Pharm Ltd 用於製備（３ｒ，３ａｓ，６ａｒ）－六氫呋喃并〔２，３－ｂ〕呋喃－３－基（１ｓ，２ｒ）－３－〔〔（４－胺基苯基）磺醯基〕（異丁基）胺基〕－１－苯甲基－２－羥基丙基胺基甲酸酯之方法
WO2010047819A1 (en) * 2008-10-24 2010-04-29 Concert Pharmaceuticals, Inc. Hydroxyethylamino sulfonamide derivatives
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
WO2011051978A2 (en) 2009-10-30 2011-05-05 Lupin Limited A novel process for preparation of darunavir and darunavir ethanolate of fine particle size
EP2528923B1 (en) 2010-01-28 2014-07-30 Mapi Pharma Limited Process for the preparation of darunavir and darunavir intermediates
US8841467B2 (en) 2010-11-23 2014-09-23 Mylan Laboratories Limited Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro [2, 3-b] furan-3-ol
WO2012075122A2 (en) * 2010-11-30 2012-06-07 Purdue Research Foundation Processes and intermediates for preparing substituted hexahydrofuro [2,3-b] furans
EP3795572B1 (en) 2012-07-24 2023-11-15 Laurus Labs Limited Darunavir propionate solvate
JPWO2014024898A1 (ja) * 2012-08-09 2016-07-25 住友化学株式会社 ヘキサヒドロフロフラノール誘導体の製造方法
CN103864813B (zh) * 2012-12-18 2017-02-22 上海迪赛诺化学制药有限公司 一种合成六氢呋喃并[2,3‑b]呋喃‑3‑醇及其对映体的方法
US10633390B2 (en) * 2015-06-25 2020-04-28 Msn Laboratories Private Limited Process for the preparation of [(1S,2R)-3-[[(4-aminophenyl)sulfonyl] (2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid (3R,3AS,6AR)hexahydro furo [2,3-B]furan-3-YL ester and its amorphous form
WO2017041228A1 (zh) * 2015-09-08 2017-03-16 浙江九洲药业股份有限公司 六氢呋喃并呋喃醇衍生物的制备方法、其中间体及其制备方法
CN107043385B (zh) * 2016-02-05 2019-07-09 成都博腾药业有限公司 一种制备地瑞那韦中间体的方法
ES2881949T3 (es) 2016-10-27 2021-11-30 Gilead Sciences Inc Forma cristalina de base libre de darunavir
CN106928248B (zh) * 2017-02-04 2019-01-04 青岛科技大学 一种制备(3R,3aS,6aR)六氢呋喃并[2,3-b]呋喃-3-醇的方法
CN116103348A (zh) 2018-03-16 2023-05-12 江苏瑞科医药科技有限公司 六氢呋喃并呋喃醇衍生物的制备方法、其中间体及其制备方法
US20240043438A1 (en) * 2020-08-11 2024-02-08 Arun K. Ghosh Methods for making darunavir p2-ligand precursors
CN114853774A (zh) * 2022-06-24 2022-08-05 盐城迪赛诺制药有限公司 一种达卢那韦关键中间体的制备方法
CN115557964A (zh) * 2022-10-18 2023-01-03 启东东岳药业有限公司 一种药物化合物的制备方法
CN117186053A (zh) * 2023-09-08 2023-12-08 上海凌凯医药科技有限公司 一种莱克酮中间体的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU35543A1 (es) * 1980-10-09 1983-05-05 Hoffmann La Roche Prostaglandines
NZ224497A (en) * 1987-05-18 1990-04-26 Janssen Pharmaceutica Nv Pharmaceutical composition comprising flunarizine
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
WO1994026749A1 (en) * 1993-05-14 1994-11-24 Merck & Co., Inc. Hiv protease inhibitors
EP0715618B1 (en) * 1993-08-24 1998-12-16 G.D. Searle & Co. Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors
RU2089545C1 (ru) * 1994-09-28 1997-09-10 Ярославский государственный технический университет Способ получения 2-метил-2-этил-1,3-диоксолан-4-ил-метилметакрилата
DE19510566A1 (de) * 1995-03-23 1996-09-26 Kali Chemie Pharma Gmbh Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19638020A1 (de) * 1996-09-18 1998-03-19 Solvay Pharm Gmbh Die gastrointestinale Durchblutung fördernde Arzneimittel
SK285019B6 (sk) * 1997-01-30 2006-04-06 Novartis Ag Tvrdá želatínová tobolka
AU4828199A (en) * 1998-06-23 2000-01-10 Board Of Trustees Of The University Of Illinois, The Multi-drug resistant retroviral protease inhibitors and associated methods
CA2872424C (en) * 1998-06-23 2017-03-07 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Bisfuran derivatives useful in preventing the emergence of multidrug resistant hiv strains and treatment of hiv
KR100336090B1 (ko) * 1998-06-27 2002-05-27 윤승원 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제
DE19906310A1 (de) * 1999-02-16 2000-08-17 Solvay Pharm Gmbh Arzneimittel zur Behandlung von Bluthochdruck
DE19932555A1 (de) * 1999-07-13 2001-01-18 Solvay Pharm Gmbh Arzneimittel mit protektiver Wirkung gegen oxidativ-toxische und insbesondere gegen kardiotoxische Substanzen
PL204924B1 (pl) 1999-10-06 2010-02-26 Tibotec Pharm Ltd Heksahydrofuro [2,3-b] furanylo-3-N-{3(1,3-benzodioksolilo-5-sulfonylo) (izobutylo) amino] -1-benzylo-2-hydroksypropylo} karbaminian oraz jego zastosowanie

Also Published As

Publication number Publication date
CN101172980A (zh) 2008-05-07
PL367817A1 (en) 2005-03-07
SI21463B (sl) 2011-08-31
CA2459168C (en) 2014-01-28
AP2004002981A0 (en) 2004-03-31
MXPA04002247A (es) 2005-09-07
US20040249175A1 (en) 2004-12-09
EA010883B1 (ru) 2008-12-30
HRP20040320A2 (en) 2005-04-30
AR036501A1 (es) 2004-09-15
PT1448567E (pt) 2010-03-12
EP1448567B1 (en) 2009-12-30
IL160166A (en) 2012-05-31
SI21463A (sl) 2004-10-31
NZ531641A (en) 2005-08-26
WO2003022853A1 (en) 2003-03-20
JP4521185B2 (ja) 2010-08-11
EP1448567A1 (en) 2004-08-25
KR20040029425A (ko) 2004-04-06
AU2002333809B2 (en) 2008-02-28
PL224030B1 (pl) 2016-11-30
KR100894673B1 (ko) 2009-04-24
AU2002333809B8 (en) 2008-07-03
CA2459168A1 (en) 2003-03-20
CN1553915A (zh) 2004-12-08
IL160166A0 (en) 2004-07-25
DE60234952D1 (de) 2010-02-11
ZA200401501B (en) 2005-07-27
AU2002333809B9 (en) 2008-06-26
AP1758A (en) 2007-07-30
AU2002333809C1 (en) 2009-02-05
ES2338538T3 (es) 2010-05-10
NO328934B1 (no) 2010-06-21
HU229505B1 (hu) 2014-01-28
EA200400430A1 (ru) 2004-08-26
HUP0402140A3 (en) 2007-05-29
BRPI0212341B8 (pt) 2021-05-25
US7126015B2 (en) 2006-10-24
CN100519561C (zh) 2009-07-29
HUP0402140A2 (hu) 2005-02-28
HK1068887A1 (en) 2005-05-06
CN101172980B (zh) 2011-11-16
BRPI0212341B1 (pt) 2019-04-02
HRP20040320B1 (hr) 2012-11-30
DK1448567T3 (da) 2010-04-26
CY1109974T1 (el) 2014-09-10
ATE453648T1 (de) 2010-01-15
JP2005502707A (ja) 2005-01-27
BR0212341A (pt) 2004-07-27

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Owner name: JANSSEN SCIENCES IRELAND UC, IE

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