NO20041601L - Forbindelse som hemmer frigjøringen av inflammatoriske cytokiner - Google Patents
Forbindelse som hemmer frigjøringen av inflammatoriske cytokinerInfo
- Publication number
- NO20041601L NO20041601L NO20041601A NO20041601A NO20041601L NO 20041601 L NO20041601 L NO 20041601L NO 20041601 A NO20041601 A NO 20041601A NO 20041601 A NO20041601 A NO 20041601A NO 20041601 L NO20041601 L NO 20041601L
- Authority
- NO
- Norway
- Prior art keywords
- substituted
- inflammatory cytokines
- release
- unsubstituted
- inhibits
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 102000004127 Cytokines Human genes 0.000 title abstract 2
- 108090000695 Cytokines Proteins 0.000 title abstract 2
- 230000002757 inflammatory effect Effects 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 125000002618 bicyclic heterocycle group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000007942 carboxylates Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical class O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Foreliggende oppfinnelse vedrører forbindelser som er i stand til å å forhindre ekstracellulær frigjøring av inflammatoriske cytokiner, hvilke forbindelser, inkludert alle enantiomeriske- og diastereomeriskeformer og farma-søytisk akseptable salter derav, har formelen:. hvori R omfattende etere eller aminer; Rer: a) substituert eller usubstituert aryl; eller b) substituert eller usubstituert heteroaryl;aogenhetene er hver uavhengig hydrogen, etere, aminer, amider, karboksylater, eller hvilke enheter har kan danne et dobbeltbinding, en karbonyl, eller Rog Rkan sammen danne et substituert eller usubstituert ring omfattende fra 4 til 8 atomer, hvilken ring er valgt fra gruppen bestående av: i) karbosyklisk;. ii) heterosyklisk;. iii) aryl;. iv) heteroaryl;. v) bisykliske; og. vi) heterobisyklisk.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32362501A | 2001-09-20 | 2001-09-20 | |
| PCT/US2002/030134 WO2003024970A1 (en) | 2001-09-20 | 2002-09-20 | Compounds which inhibit the release of inflammatory cytokines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20041601L true NO20041601L (no) | 2004-06-21 |
Family
ID=69642561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20041601A NO20041601L (no) | 2001-09-20 | 2004-04-20 | Forbindelse som hemmer frigjøringen av inflammatoriske cytokiner |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO20041601L (no) |
-
2004
- 2004-04-20 NO NO20041601A patent/NO20041601L/no unknown
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