NO20041921L - Peroksisom proliferator-aktivert reseptorligand og fremgangsmate for fremstilling av denne - Google Patents

Peroksisom proliferator-aktivert reseptorligand og fremgangsmate for fremstilling av denne

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Publication number
NO20041921L
NO20041921L NO20041921A NO20041921A NO20041921L NO 20041921 L NO20041921 L NO 20041921L NO 20041921 A NO20041921 A NO 20041921A NO 20041921 A NO20041921 A NO 20041921A NO 20041921 L NO20041921 L NO 20041921L
Authority
NO
Norway
Prior art keywords
activated receptor
peroxisome proliferator
receptor ligand
preparation
ligand
Prior art date
Application number
NO20041921A
Other languages
English (en)
Other versions
NO20041921D0 (no
Inventor
Yasuyoshi Ueda
Tatsumasa Mae
Misuzu Tsukagawa
Mikio Kitahara
Kaku Nakagawa
Shiro Kitamura
Yutaka Sahida
Minpei Kuroda
Yoshihiro Mimaki
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of NO20041921D0 publication Critical patent/NO20041921D0/no
Publication of NO20041921L publication Critical patent/NO20041921L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Birds (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)

Abstract

Den foreliggende oppfinnelsen tilveiebringer lett og effektiv en peroksisom proliferator-aktivert reseptorligand og en sammensetning for forbedring av insulinresistens eller for hindring og/eller forbedring av insulinresistens syndromet inneholdende denne som en aktiv ingrediens.Den foreliggende oppfinnelsen vedrører en peroksisom proliferator-aktivert reseptorligand som omfatter en prenylflavonoid, et kalkonderivat eksklusiv prenylflavonoider, et flavonolderivat eksklusiv prenylflavonoider og et salt, et glykosid og/eller en estrifisert substans derav akseptabel som et farmasøytisk preparat eller matvare eller en drikk, en sammensetning inneholdende ovennevnte ligand, et plateavledet ekstrakt inneholdende den ovenfor nevnte liganden og en fremgangsmåte for fremstilling av det ovenfor nevnte ekstraktet.
NO20041921A 2001-10-11 2004-05-10 Peroksisom proliferator-aktivert reseptorligand og fremgangsmate for fremstilling av denne NO20041921L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2001313816 2001-10-11
JP2002006304 2002-01-15
JP2002042466 2002-02-20
JP2002226486 2002-08-02
PCT/JP2002/010572 WO2003037316A1 (en) 2001-10-11 2002-10-11 Peroxisome proliferator activated receptor ligands and process for producing the same

Publications (2)

Publication Number Publication Date
NO20041921D0 NO20041921D0 (no) 2004-05-10
NO20041921L true NO20041921L (no) 2004-07-06

Family

ID=27482611

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20041921A NO20041921L (no) 2001-10-11 2004-05-10 Peroksisom proliferator-aktivert reseptorligand og fremgangsmate for fremstilling av denne

Country Status (9)

Country Link
US (2) US7524975B2 (no)
EP (1) EP1440688A4 (no)
JP (1) JPWO2003037316A1 (no)
KR (1) KR20050035142A (no)
CN (1) CN1599602A (no)
CA (1) CA2460134A1 (no)
IL (1) IL160964A0 (no)
NO (1) NO20041921L (no)
WO (1) WO2003037316A1 (no)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200416037A (en) * 2002-02-20 2004-09-01 Kanegafuchi Chemical Ind Process for producing hydrophobic glycyrrhiza extract with high qualities
TW200427410A (en) * 2003-01-24 2004-12-16 Kaneka Corp Processed fat compositions for preventing and improving lifestyle-related diseases
JPWO2004096198A1 (ja) * 2003-05-02 2006-07-13 タカラバイオ株式会社 治療剤
US20050096256A1 (en) 2003-07-01 2005-05-05 President And Fellows Of Harvard College Compositions for manipulating the lifespan and stress response of cells and organisms
TW200513194A (en) * 2003-07-31 2005-04-16 Kaneka Corp Fat and oil processed composition for prevention and/or amelioration of life-style related disease
EP1735069A1 (en) * 2003-10-24 2006-12-27 Native Fire Actives Pty Ltd Extraction process
DE10357452A1 (de) * 2003-12-03 2005-06-30 Beiersdorf Ag Kosmetische Zubereitungen mit einem Gehalt an Licochalcon A oder einem Extrakt aus Radix Glycyrrhizae inflatae, enthaltend Licochalcon A, und organischen Verdicker
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
EP1708689A2 (en) 2003-12-29 2006-10-11 The President and Fellows of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
BRPI0506718A (pt) 2004-01-08 2007-05-02 Genfit compostos, processo de preparação dos mesmos, e, composição farmacêutica ou cosmética
JPWO2005074906A1 (ja) * 2004-02-06 2008-01-10 タカラバイオ株式会社 治療剤
JP2005320281A (ja) * 2004-05-10 2005-11-17 Shiratori Pharmaceutical Co Ltd インスリン分泌促進剤及び飲食品
TW200612902A (en) * 2004-05-13 2006-05-01 Kaneka Corp Inhibiting agents for lipase or cholesterol esterase, and absorption suppressing agents for neutral fat, cholesterol, or cholesterol ester
US20060040876A1 (en) * 2004-06-10 2006-02-23 Rong-Hwa Lin Modulation of peroxisome proliferator-activated receptors
CA2574898C (en) * 2004-07-23 2011-12-20 Tsung-Chung Lin Immune modulation and anti-allergy activities of zingiber zerumbet
EP1829542B1 (en) * 2004-11-08 2012-07-18 ARKRAY, Inc. Peroxisome proliferator-activated receptor (ppar) activator and drug, supplement, functional food and food additive using the same
JPWO2006085562A1 (ja) * 2005-02-09 2008-06-26 株式会社カネカ メタボリックシンドローム及びインスリン抵抗性症候群の予防及び／又は処置用組成物
WO2006106705A1 (ja) 2005-03-30 2006-10-12 Kaneka Corporation 発癌抑制用油脂含有組成物
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
WO2006136423A2 (en) * 2005-06-24 2006-12-28 Dsm Ip Assets B.V. Medicament for the treatment of impaired glucose metabolism
US20070149466A1 (en) * 2005-07-07 2007-06-28 Michael Milburn Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
JP2007063161A (ja) * 2005-08-30 2007-03-15 Kaneka Corp 急性相反応タンパク質転写抑制活性剤。
JP4954531B2 (ja) * 2005-10-31 2012-06-20 一丸ファルコス株式会社 ペルオキシソーム増殖剤応答性受容体活性化剤
JP4732854B2 (ja) * 2005-10-31 2011-07-27 一丸ファルコス株式会社 ペルオキシソーム増殖剤応答性受容体活性化剤
JP2007119429A (ja) * 2005-10-31 2007-05-17 Ichimaru Pharcos Co Ltd ペルオキシソーム増殖剤応答性受容体活性化剤
WO2007058480A1 (en) * 2005-11-16 2007-05-24 Md Bioalpha Co., Ltd. Composition having effect on treatment and prevention of diseases syndrome treatment with glabridin
WO2007060992A1 (ja) * 2005-11-25 2007-05-31 Kaneka Corporation メタボリックシンドロームもしくはインスリン抵抗性症候群の予防または改善剤
JP5246833B2 (ja) * 2005-12-16 2013-07-24 独立行政法人産業技術総合研究所 アディポネクチン産生増強剤
JP5246834B2 (ja) * 2005-12-27 2013-07-24 独立行政法人産業技術総合研究所 アディポネクチン産生強化剤
JP5158742B2 (ja) * 2006-11-10 2013-03-06 独立行政法人産業技術総合研究所 炎症性インターロイキン産生抑制剤
US11241420B2 (en) 2007-04-11 2022-02-08 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
WO2008128126A1 (en) * 2007-04-11 2008-10-23 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
US20160331729A9 (en) * 2007-04-11 2016-11-17 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
US8877266B2 (en) 2007-05-02 2014-11-04 Tom's Of Maine, Inc. Supercritical CO2 liquorice extract anti-microbial and anti-inflammatory isolates and products made there from
US8236360B2 (en) * 2007-05-02 2012-08-07 Tom's Of Maine, Inc. Supercritical CO2 liquorice extract and products made there from
US20080274063A1 (en) * 2007-05-02 2008-11-06 Chantal Bergeron Supercritical CO2 liquorice extract anti-microbial and anti-inflammatory isolates and products made there from
US20080286254A1 (en) * 2007-05-17 2008-11-20 Kaneka Corporation Composition comprising licorice polyphenol
JP2009001523A (ja) * 2007-06-22 2009-01-08 Maruzen Pharmaceut Co Ltd 抗男性ホルモン剤、育毛剤及び頭髪化粧料
EP2186789B1 (en) 2007-08-22 2013-12-25 Kaneka Corporation Method of producing reduced coenzyme q10 and method of stabilizing the same
WO2009026657A1 (en) * 2007-08-29 2009-03-05 The University Of Sydney Flavonoid ppar agonists
CN101434592B (zh) * 2008-12-19 2014-06-25 沈阳药科大学 朝鲜槐中提取的黄酮类化合物
KR101052594B1 (ko) 2009-03-10 2011-07-29 한국생명공학연구원 디아실 코에이:글리세롤 아실트랜스퍼라제 저해활성을 갖는감초 추출물, 이의 용매분획물 또는 이로부터 분리된 화합물을 포함하는 조성물
KR101034624B1 (ko) * 2009-06-17 2011-05-12 울산대학교 산학협력단 디디에이에이치를 활성화시키는 감초 유래의 칼콘 화합물 및 이를 유효성분으로 하는 췌장 베타세포 사멸 및 당뇨병성 신증의 예방 또는 치료용 조성물
CA2800337C (en) 2010-05-17 2019-01-29 Genfit Improved preparation of chalcone derivatives
EP3915367A1 (en) 2010-08-18 2021-12-01 BioSplice Therapeutics, Inc. Diketones and hydroxyketones as catenin signaling pathway activators
JP6010281B2 (ja) * 2011-03-03 2016-10-19 株式会社カネカ 筋肉増量剤
CN103608024B (zh) 2011-04-01 2016-04-13 桂林商源植物制品有限公司 控制血糖、血脂及体重的药物组合物
KR101060942B1 (ko) * 2011-04-21 2011-08-30 경희대학교 산학협력단 리코찰콘 ａ의 신규 용도
CA2839301C (en) 2011-06-15 2021-02-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nuclear receptor modulators and their use for the treatment and prevention of cancer
TWI417088B (zh) 2011-08-10 2013-12-01 Univ Kaohsiung Medical 用於治療糖尿病及新陳代謝疾病的組合物及其製備方法
JP6036193B2 (ja) * 2012-11-09 2016-11-30 国立大学法人富山大学 インフラマソーム活性制御剤
PE20151721A1 (es) 2013-02-22 2015-12-07 Samumed Llc Y-dicetonas como activadores de la ruta de senalizacion de wnt/b-catenina
JP6245867B2 (ja) * 2013-07-05 2017-12-13 ソマール株式会社 ＰＰＡＲγ活性向上剤及びそれを用いた経口組成物
CN103565800B (zh) * 2013-10-30 2015-06-17 中国农业大学 甘草香豆素在制备用于预防/治疗酒精性肝损伤的产品中的应用
KR102344479B1 (ko) * 2013-12-24 2021-12-29 주식회사 글라세움 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물
JP6289218B2 (ja) * 2014-03-31 2018-03-07 大阪瓦斯株式会社 ＰＰＡＲα活性組成物の活性化方法
US10045540B2 (en) 2014-04-01 2018-08-14 Fayetteville State University Pest control composition
DK3206686T3 (da) 2014-08-20 2019-12-16 Samumed Llc Gamma-diketoner til behandling og forebyggelse af ældning af huden og rynker
CN105232501B (zh) * 2015-11-17 2019-01-08 北京大学 刺甘草査尔酮的用途
CN105582005B (zh) * 2015-12-11 2018-06-19 北京大学 甘草中一类异戊烯基异黄酮类化合物的医药用途
CN105963291B (zh) * 2016-06-02 2019-05-24 上海中医药大学 异补骨脂二氢黄酮及其类似物的医药用途
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CN106580951B (zh) * 2016-11-17 2019-07-30 珠海雅光生物工程有限公司 一种黄烷酮化合物的新用途
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CN114031625B (zh) * 2021-11-22 2023-05-30 兰州大学 甘草中具有抗结直肠癌活性的化合物制备及其应用
CN121752267A (zh) * 2023-08-15 2026-03-27 爱睦健制药株式会社 针对脂肪分解及/或体重减少的内用组成物、判定有效性的方法、以及植物提取物的质量指标
CN117603175B (zh) * 2023-11-27 2024-08-06 南开大学 一种苯并吡喃结构的查尔酮类衍生物及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990006108A1 (fr) 1988-11-25 1990-06-14 Dainippon Ink And Chemicals, Inc. Agent anti-inflammatoire polyvalent
JP2753719B2 (ja) 1988-12-15 1998-05-20 日本油脂株式会社 リポソーム製剤の製造法
JPH0368157A (ja) * 1989-08-05 1991-03-25 Mitsubishi Electric Corp 高周波用厚膜集積回路装置
JPH0368517A (ja) * 1989-08-08 1991-03-25 Tsumura & Co アルドースリダクターゼ阻害剤
JPH04297418A (ja) 1991-02-07 1992-10-21 Sumitomo Metal Ind Ltd 血小板凝集抑制剤および白血球活性化抑制剤
EP0499015A1 (en) * 1991-02-15 1992-08-19 Fockerman, Jasmine Benzopyran phenol derivates for use as antibacterial, antiviral or immunostimulating agents
JP3052104B2 (ja) * 1992-11-19 2000-06-12 丸善製薬株式会社 皮膚化粧料
JPH07165588A (ja) * 1993-12-13 1995-06-27 Tsumura & Co 脳機能改善剤
JPH0873337A (ja) 1994-09-07 1996-03-19 Ogawa Koryo Kk 外用剤組成物
US6251400B1 (en) 1997-09-26 2001-06-26 Kgk Synergize Inc Compositions and methods of treatment of neoplastic diseases and hypercholesterolemia with citrus limonoids and flavonoids and tocotrienols
JP3069686B2 (ja) * 1997-12-08 2000-07-24 農林水産省四国農業試験場長 フラバノン類含有組成物
WO1999037633A1 (en) 1998-01-27 1999-07-29 Shionogi & Co., Ltd. Isoflavane derivatives and immunopotentiating compositions containing the same
JP3648587B2 (ja) * 1998-03-04 2005-05-18 サンスター株式会社 歯周病予防又は歯周病進行予防食品組成物
JP3542284B2 (ja) * 1998-09-08 2004-07-14 シマノ シンガポール ピーティーイー．リミテッド． 釣り用リール
JP2982872B1 (ja) * 1998-09-10 1999-11-29 有限会社松川化学 痩身用皮膚外用剤
KR20000019716A (ko) * 1998-09-15 2000-04-15 박호군 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물
JP4418550B2 (ja) 1999-02-17 2010-02-17 丸善製薬株式会社 疎水性甘草エキス含有組成物
JP2000355538A (ja) 1999-04-15 2000-12-26 Kanegafuchi Chem Ind Co Ltd ペルオキシゾーム活性化剤応答性受容体アゴニスト
KR20020070508A (ko) 2000-01-28 2002-09-09 노보 노르디스크 에이/에스 프로피온산 유도체 및 당뇨병 및 비만의 치료에 그것의 사용
KR100472694B1 (ko) * 2000-12-30 2005-03-07 한국생명공학연구원 플라바논 유도체 및 이를 포함하는 혈중 지질 농도 관련질환의 예방 및 치료용 조성물

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