NO20041921L - Peroksisom proliferator-aktivert reseptorligand og fremgangsmate for fremstilling av denne - Google Patents
Peroksisom proliferator-aktivert reseptorligand og fremgangsmate for fremstilling av denneInfo
- Publication number
- NO20041921L NO20041921L NO20041921A NO20041921A NO20041921L NO 20041921 L NO20041921 L NO 20041921L NO 20041921 A NO20041921 A NO 20041921A NO 20041921 A NO20041921 A NO 20041921A NO 20041921 L NO20041921 L NO 20041921L
- Authority
- NO
- Norway
- Prior art keywords
- activated receptor
- peroxisome proliferator
- receptor ligand
- preparation
- ligand
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 5
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title abstract 3
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title abstract 3
- 229930008679 prenylflavonoid Natural products 0.000 abstract 3
- 150000007951 prenylflavonoids Chemical class 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 208000031773 Insulin resistance syndrome Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 235000013361 beverage Nutrition 0.000 abstract 1
- 150000002216 flavonol derivatives Chemical class 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Birds (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
Abstract
Den foreliggende oppfinnelsen tilveiebringer lett og effektiv en peroksisom proliferator-aktivert reseptorligand og en sammensetning for forbedring av insulinresistens eller for hindring og/eller forbedring av insulinresistens syndromet inneholdende denne som en aktiv ingrediens.Den foreliggende oppfinnelsen vedrører en peroksisom proliferator-aktivert reseptorligand som omfatter en prenylflavonoid, et kalkonderivat eksklusiv prenylflavonoider, et flavonolderivat eksklusiv prenylflavonoider og et salt, et glykosid og/eller en estrifisert substans derav akseptabel som et farmasøytisk preparat eller matvare eller en drikk, en sammensetning inneholdende ovennevnte ligand, et plateavledet ekstrakt inneholdende den ovenfor nevnte liganden og en fremgangsmåte for fremstilling av det ovenfor nevnte ekstraktet.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001313816 | 2001-10-11 | ||
| JP2002006304 | 2002-01-15 | ||
| JP2002042466 | 2002-02-20 | ||
| JP2002226486 | 2002-08-02 | ||
| PCT/JP2002/010572 WO2003037316A1 (en) | 2001-10-11 | 2002-10-11 | Peroxisome proliferator activated receptor ligands and process for producing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20041921D0 NO20041921D0 (no) | 2004-05-10 |
| NO20041921L true NO20041921L (no) | 2004-07-06 |
Family
ID=27482611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20041921A NO20041921L (no) | 2001-10-11 | 2004-05-10 | Peroksisom proliferator-aktivert reseptorligand og fremgangsmate for fremstilling av denne |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7524975B2 (no) |
| EP (1) | EP1440688A4 (no) |
| JP (1) | JPWO2003037316A1 (no) |
| KR (1) | KR20050035142A (no) |
| CN (1) | CN1599602A (no) |
| CA (1) | CA2460134A1 (no) |
| IL (1) | IL160964A0 (no) |
| NO (1) | NO20041921L (no) |
| WO (1) | WO2003037316A1 (no) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200416037A (en) * | 2002-02-20 | 2004-09-01 | Kanegafuchi Chemical Ind | Process for producing hydrophobic glycyrrhiza extract with high qualities |
| TW200427410A (en) * | 2003-01-24 | 2004-12-16 | Kaneka Corp | Processed fat compositions for preventing and improving lifestyle-related diseases |
| TW200509886A (en) * | 2003-05-02 | 2005-03-16 | Takara Bio Inc | Therapeutic agent |
| WO2005002672A2 (en) | 2003-07-01 | 2005-01-13 | President And Fellows Of Harvard College | Sirt1 modulators for manipulating cells/organism lifespan/stress response |
| TW200513194A (en) * | 2003-07-31 | 2005-04-16 | Kaneka Corp | Fat and oil processed composition for prevention and/or amelioration of life-style related disease |
| WO2005039727A1 (en) * | 2003-10-24 | 2005-05-06 | Native Fire Actives Pty Ltd | Extraction process |
| DE10357452A1 (de) * | 2003-12-03 | 2005-06-30 | Beiersdorf Ag | Kosmetische Zubereitungen mit einem Gehalt an Licochalcon A oder einem Extrakt aus Radix Glycyrrhizae inflatae, enthaltend Licochalcon A, und organischen Verdicker |
| AU2004312072B2 (en) | 2003-12-29 | 2011-06-23 | President And Fellows Of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
| US8017634B2 (en) * | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| KR20060132903A (ko) | 2004-01-08 | 2006-12-22 | 장피트 | 1,3-디페닐프로프-2-엔-1-온 유도체 화합물, 그 제조방법및 용도 |
| JPWO2005074906A1 (ja) * | 2004-02-06 | 2008-01-10 | タカラバイオ株式会社 | 治療剤 |
| JP2005320281A (ja) * | 2004-05-10 | 2005-11-17 | Shiratori Pharmaceutical Co Ltd | インスリン分泌促進剤及び飲食品 |
| TW200612902A (en) * | 2004-05-13 | 2006-05-01 | Kaneka Corp | Inhibiting agents for lipase or cholesterol esterase, and absorption suppressing agents for neutral fat, cholesterol, or cholesterol ester |
| US20060040876A1 (en) * | 2004-06-10 | 2006-02-23 | Rong-Hwa Lin | Modulation of peroxisome proliferator-activated receptors |
| US7588788B2 (en) * | 2004-07-23 | 2009-09-15 | Wholesome Life Science Co., Ltd. | Immune modulation and anti-allergy activities of Zingiber zerumbet |
| CN101052391A (zh) * | 2004-11-08 | 2007-10-10 | 爱科来株式会社 | 过氧化物酶体增殖物激活受体(ppar)活化剂以及使用了该活化剂的药品、补充剂、功能性食品和食品添加剂 |
| WO2006085562A1 (ja) * | 2005-02-09 | 2006-08-17 | Kaneka Corporation | メタボリックシンドローム及びインスリン抵抗性症候群の予防及び/又は処置用組成物 |
| US20090041876A1 (en) * | 2005-03-30 | 2009-02-12 | Kaneka Corporation | Oil/fat-containing composition for suppression of carcinogenesis |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| KR20080019242A (ko) * | 2005-06-24 | 2008-03-03 | 디에스엠 아이피 어셋츠 비.브이. | 글루코스 대사부전 치료용 약제 |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| JP2007063161A (ja) * | 2005-08-30 | 2007-03-15 | Kaneka Corp | 急性相反応タンパク質転写抑制活性剤。 |
| JP2007119429A (ja) * | 2005-10-31 | 2007-05-17 | Ichimaru Pharcos Co Ltd | ペルオキシソーム増殖剤応答性受容体活性化剤 |
| JP4732854B2 (ja) * | 2005-10-31 | 2011-07-27 | 一丸ファルコス株式会社 | ペルオキシソーム増殖剤応答性受容体活性化剤 |
| JP4954531B2 (ja) * | 2005-10-31 | 2012-06-20 | 一丸ファルコス株式会社 | ペルオキシソーム増殖剤応答性受容体活性化剤 |
| KR20070052211A (ko) * | 2005-11-16 | 2007-05-21 | 주식회사 엠디바이오알파 | 글라브리딘을 유효성분으로 함유하는 질환 증후군 예방 및치료용 조성물 |
| WO2007060992A1 (ja) * | 2005-11-25 | 2007-05-31 | Kaneka Corporation | メタボリックシンドロームもしくはインスリン抵抗性症候群の予防または改善剤 |
| JP5246833B2 (ja) * | 2005-12-16 | 2013-07-24 | 独立行政法人産業技術総合研究所 | アディポネクチン産生増強剤 |
| JP5246834B2 (ja) * | 2005-12-27 | 2013-07-24 | 独立行政法人産業技術総合研究所 | アディポネクチン産生強化剤 |
| JP5158742B2 (ja) * | 2006-11-10 | 2013-03-06 | 独立行政法人産業技術総合研究所 | 炎症性インターロイキン産生抑制剤 |
| CN110403942A (zh) * | 2007-04-11 | 2019-11-05 | 奥默罗斯公司 | 预防和治疗成瘾的组合物和方法 |
| US20160331729A9 (en) | 2007-04-11 | 2016-11-17 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| US11241420B2 (en) | 2007-04-11 | 2022-02-08 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| US20080274063A1 (en) * | 2007-05-02 | 2008-11-06 | Chantal Bergeron | Supercritical CO2 liquorice extract anti-microbial and anti-inflammatory isolates and products made there from |
| US8236360B2 (en) * | 2007-05-02 | 2012-08-07 | Tom's Of Maine, Inc. | Supercritical CO2 liquorice extract and products made there from |
| US8877266B2 (en) | 2007-05-02 | 2014-11-04 | Tom's Of Maine, Inc. | Supercritical CO2 liquorice extract anti-microbial and anti-inflammatory isolates and products made there from |
| JPWO2008143182A1 (ja) * | 2007-05-17 | 2010-08-05 | 株式会社カネカ | 甘草ポリフェノールを含有する組成物 |
| JP2009001523A (ja) * | 2007-06-22 | 2009-01-08 | Maruzen Pharmaceut Co Ltd | 抗男性ホルモン剤、育毛剤及び頭髪化粧料 |
| JP5364580B2 (ja) | 2007-08-22 | 2013-12-11 | 株式会社カネカ | 還元型補酵素q10の製造方法、ならびに、その安定化方法 |
| WO2009026657A1 (en) * | 2007-08-29 | 2009-03-05 | The University Of Sydney | Flavonoid ppar agonists |
| CN101434592B (zh) * | 2008-12-19 | 2014-06-25 | 沈阳药科大学 | 朝鲜槐中提取的黄酮类化合物 |
| KR101052594B1 (ko) | 2009-03-10 | 2011-07-29 | 한국생명공학연구원 | 디아실 코에이:글리세롤 아실트랜스퍼라제 저해활성을 갖는감초 추출물, 이의 용매분획물 또는 이로부터 분리된 화합물을 포함하는 조성물 |
| KR101034624B1 (ko) * | 2009-06-17 | 2011-05-12 | 울산대학교 산학협력단 | 디디에이에이치를 활성화시키는 감초 유래의 칼콘 화합물 및 이를 유효성분으로 하는 췌장 베타세포 사멸 및 당뇨병성 신증의 예방 또는 치료용 조성물 |
| NO2571843T3 (no) | 2010-05-17 | 2018-05-26 | ||
| MX354133B (es) | 2010-08-18 | 2018-02-14 | Samumed Llc | Dicetonas e hidroxicetonas como activadores de la trayectoria de señalizacion de catenina. |
| JP6010281B2 (ja) * | 2011-03-03 | 2016-10-19 | 株式会社カネカ | 筋肉増量剤 |
| CN103608024B (zh) | 2011-04-01 | 2016-04-13 | 桂林商源植物制品有限公司 | 控制血糖、血脂及体重的药物组合物 |
| KR101060942B1 (ko) * | 2011-04-21 | 2011-08-30 | 경희대학교 산학협력단 | 리코찰콘 a의 신규 용도 |
| EP2721003B1 (en) | 2011-06-15 | 2018-01-03 | The United States of America, as Represented by The Secretary, Department of Health and Human Services | Nuclear receptor modulators and their use for the treatment and prevention of cancer |
| TWI417088B (zh) | 2011-08-10 | 2013-12-01 | Univ Kaohsiung Medical | 用於治療糖尿病及新陳代謝疾病的組合物及其製備方法 |
| JP6036193B2 (ja) * | 2012-11-09 | 2016-11-30 | 国立大学法人富山大学 | インフラマソーム活性制御剤 |
| EP3456325A3 (en) | 2013-02-22 | 2019-05-22 | Samumed, LLC | Gamma-diketones as wnt/beta-catenin signalling pathway activators |
| JP6245867B2 (ja) * | 2013-07-05 | 2017-12-13 | ソマール株式会社 | PPARγ活性向上剤及びそれを用いた経口組成物 |
| CN103565800B (zh) * | 2013-10-30 | 2015-06-17 | 中国农业大学 | 甘草香豆素在制备用于预防/治疗酒精性肝损伤的产品中的应用 |
| KR102344479B1 (ko) * | 2013-12-24 | 2021-12-29 | 주식회사 글라세움 | 피라노크로메닐페놀 유도체, 및 대사증후군 또는 염증 질환 치료용 약학 조성물 |
| JP6289218B2 (ja) * | 2014-03-31 | 2018-03-07 | 大阪瓦斯株式会社 | PPARα活性組成物の活性化方法 |
| US10045540B2 (en) | 2014-04-01 | 2018-08-14 | Fayetteville State University | Pest control composition |
| SI3206686T1 (sl) | 2014-08-20 | 2020-03-31 | Samumed, Llc | Gama-diketoni za zdravljenje in preprečevanje staranja kože in gub |
| CN105232501B (zh) * | 2015-11-17 | 2019-01-08 | 北京大学 | 刺甘草査尔酮的用途 |
| CN105582005B (zh) * | 2015-12-11 | 2018-06-19 | 北京大学 | 甘草中一类异戊烯基异黄酮类化合物的医药用途 |
| CN105963291B (zh) * | 2016-06-02 | 2019-05-24 | 上海中医药大学 | 异补骨脂二氢黄酮及其类似物的医药用途 |
| BR112018077392A2 (pt) * | 2016-06-29 | 2019-04-09 | Glaceum, Inc. | composição farmacêutica e derivado de piranocromenil fenol oticamente ativo compreendendo a mesma |
| CN106580951B (zh) * | 2016-11-17 | 2019-07-30 | 珠海雅光生物工程有限公司 | 一种黄烷酮化合物的新用途 |
| CN108997296B (zh) * | 2018-08-18 | 2022-02-18 | 内蒙古大学 | 几种异戊烯基二氢茋和异戊烯基黄酮的结构和用途 |
| CN110872306B (zh) * | 2018-08-30 | 2022-03-22 | 复旦大学 | 一种从藤构中提取的化合物及其在制药中的用途 |
| CN110872267B (zh) * | 2018-08-30 | 2022-07-08 | 复旦大学 | 一种从构树中提取的化合物及其在制备蛋白酪氨酸磷酸酶1b抑制剂中的用途 |
| CN109223762A (zh) * | 2018-09-26 | 2019-01-18 | 兰州大学第医院 | 光甘草素在制备抗癌药物中的应用 |
| CN109232603B (zh) * | 2018-10-29 | 2020-12-22 | 陕西师范大学 | 一种光甘草定的合成方法 |
| WO2020153413A1 (ja) * | 2019-01-22 | 2020-07-30 | 株式会社 沖縄リサーチセンター | PPARγ活性化用組成物及び糖取込み促進能向上用組成物 |
| CN110772504B (zh) * | 2019-02-27 | 2021-06-22 | 中国人民解放军总医院第五医学中心 | 刺甘草查尔酮作为抑制剂的用途 |
| CN110025603A (zh) * | 2019-05-15 | 2019-07-19 | 大连天星本草生物科技有限公司 | 补骨脂查尔酮类化合物在制备治疗肥胖症的药物中的应用 |
| CN111714489A (zh) * | 2019-12-10 | 2020-09-29 | 德萌达生物医药科技(杭州)有限公司 | 对肿瘤具有杀伤作用的双拓扑异构酶抑制剂及其制备方法 |
| EP4205737A4 (en) * | 2020-08-05 | 2024-07-31 | University-Industry Cooperation Group Of Kyung Hee University | Composition for prevention, amelioration, or treatment of inflammatory diseases or immune diseases comprising gancaonin n as active ingredient |
| CN112047916A (zh) * | 2020-09-21 | 2020-12-08 | 苏州昊帆生物股份有限公司 | 异甘草黄酮醇的合成方法 |
| CN112791081A (zh) * | 2021-01-26 | 2021-05-14 | 云南农业大学 | 怀特酮在制备肺癌治疗药物中的应用 |
| CN113332294A (zh) * | 2021-05-25 | 2021-09-03 | 成都中医药大学 | 一种中药甘草抗肿瘤活性成分配伍组合物 |
| CN114031625B (zh) * | 2021-11-22 | 2023-05-30 | 兰州大学 | 甘草中具有抗结直肠癌活性的化合物制备及其应用 |
| WO2025037604A1 (ja) * | 2023-08-15 | 2025-02-20 | エムジーファーマ株式会社 | 脂肪分解及び/又は体重減少に対する内用組成物、有効性を判定する方法、並びに植物抽出物の品質の指標 |
| CN117603175B (zh) * | 2023-11-27 | 2024-08-06 | 南开大学 | 一种苯并吡喃结构的查尔酮类衍生物及其制备方法和应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR940011244B1 (ko) * | 1988-11-25 | 1994-12-03 | 다이닛뽕잉끼 가가꾸 고오교오 가부시끼가이샤 | 신장 질환 치료제 |
| JP2753719B2 (ja) | 1988-12-15 | 1998-05-20 | 日本油脂株式会社 | リポソーム製剤の製造法 |
| JPH0368157A (ja) * | 1989-08-05 | 1991-03-25 | Mitsubishi Electric Corp | 高周波用厚膜集積回路装置 |
| JPH0368517A (ja) * | 1989-08-08 | 1991-03-25 | Tsumura & Co | アルドースリダクターゼ阻害剤 |
| JPH04297418A (ja) * | 1991-02-07 | 1992-10-21 | Sumitomo Metal Ind Ltd | 血小板凝集抑制剤および白血球活性化抑制剤 |
| EP0499015A1 (en) * | 1991-02-15 | 1992-08-19 | Fockerman, Jasmine | Benzopyran phenol derivates for use as antibacterial, antiviral or immunostimulating agents |
| JP3052104B2 (ja) * | 1992-11-19 | 2000-06-12 | 丸善製薬株式会社 | 皮膚化粧料 |
| JPH07165588A (ja) * | 1993-12-13 | 1995-06-27 | Tsumura & Co | 脳機能改善剤 |
| JPH0873337A (ja) | 1994-09-07 | 1996-03-19 | Ogawa Koryo Kk | 外用剤組成物 |
| US6251400B1 (en) | 1997-09-26 | 2001-06-26 | Kgk Synergize Inc | Compositions and methods of treatment of neoplastic diseases and hypercholesterolemia with citrus limonoids and flavonoids and tocotrienols |
| JP3069686B2 (ja) | 1997-12-08 | 2000-07-24 | 農林水産省四国農業試験場長 | フラバノン類含有組成物 |
| EP1057825A4 (en) * | 1998-01-27 | 2001-10-24 | Shionogi & Co | ISOFLAVANE DERIVATIVES AND IMMUNOSTIMULATING COMPOSITIONS CONTAINING THEM |
| JP3648587B2 (ja) * | 1998-03-04 | 2005-05-18 | サンスター株式会社 | 歯周病予防又は歯周病進行予防食品組成物 |
| JP3542284B2 (ja) * | 1998-09-08 | 2004-07-14 | シマノ シンガポール ピーティーイー.リミテッド. | 釣り用リール |
| JP2982872B1 (ja) * | 1998-09-10 | 1999-11-29 | 有限会社松川化学 | 痩身用皮膚外用剤 |
| KR20000019716A (ko) * | 1998-09-15 | 2000-04-15 | 박호군 | 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물 |
| JP4418550B2 (ja) | 1999-02-17 | 2010-02-17 | 丸善製薬株式会社 | 疎水性甘草エキス含有組成物 |
| JP2000355538A (ja) | 1999-04-15 | 2000-12-26 | Kanegafuchi Chem Ind Co Ltd | ペルオキシゾーム活性化剤応答性受容体アゴニスト |
| KR20020070508A (ko) | 2000-01-28 | 2002-09-09 | 노보 노르디스크 에이/에스 | 프로피온산 유도체 및 당뇨병 및 비만의 치료에 그것의 사용 |
| KR100472694B1 (ko) * | 2000-12-30 | 2005-03-07 | 한국생명공학연구원 | 플라바논 유도체 및 이를 포함하는 혈중 지질 농도 관련질환의 예방 및 치료용 조성물 |
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| US20090036519A1 (en) | 2009-02-05 |
| KR20050035142A (ko) | 2005-04-15 |
| CA2460134A1 (en) | 2003-05-08 |
| US20050014819A1 (en) | 2005-01-20 |
| JPWO2003037316A1 (ja) | 2005-02-17 |
| NO20041921D0 (no) | 2004-05-10 |
| IL160964A0 (en) | 2004-08-31 |
| EP1440688A4 (en) | 2005-11-30 |
| EP1440688A1 (en) | 2004-07-28 |
| CN1599602A (zh) | 2005-03-23 |
| US7888388B2 (en) | 2011-02-15 |
| US7524975B2 (en) | 2009-04-28 |
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