NO20042731L - Fremgangsmater for rensing av levofloxacin - Google Patents

Fremgangsmater for rensing av levofloxacin

Info

Publication number
NO20042731L
NO20042731L NO20042731A NO20042731A NO20042731L NO 20042731 L NO20042731 L NO 20042731L NO 20042731 A NO20042731 A NO 20042731A NO 20042731 A NO20042731 A NO 20042731A NO 20042731 L NO20042731 L NO 20042731L
Authority
NO
Norway
Prior art keywords
levofloxacin
purifying
methods
purified
antioxidant
Prior art date
Application number
NO20042731A
Other languages
English (en)
Norwegian (no)
Inventor
Valerie Niddam-Hildesheim
Neomi Gershon
Eduard Schwartz
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/263,192 external-priority patent/US7629458B2/en
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of NO20042731L publication Critical patent/NO20042731L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
NO20042731A 2001-11-29 2004-06-29 Fremgangsmater for rensing av levofloxacin NO20042731L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33431601P 2001-11-29 2001-11-29
US35493902P 2002-02-11 2002-02-11
US26296502A 2002-10-03 2002-10-03
US10/263,192 US7629458B2 (en) 2001-10-03 2002-10-03 Preparation of levofloxacin and hemihydrate thereof
PCT/US2002/038182 WO2003045329A2 (en) 2001-11-29 2002-11-27 Methods for the purification of levofloxacin

Publications (1)

Publication Number Publication Date
NO20042731L true NO20042731L (no) 2004-06-29

Family

ID=31892240

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20042731A NO20042731L (no) 2001-11-29 2004-06-29 Fremgangsmater for rensing av levofloxacin

Country Status (13)

Country Link
EP (1) EP1460997A4 (pl)
JP (3) JP2005527484A (pl)
CN (1) CN1596256A (pl)
AU (1) AU2002365416A1 (pl)
CA (1) CA2466860A1 (pl)
HR (1) HRP20040546A2 (pl)
HU (1) HUP0500285A3 (pl)
IL (1) IL162172A0 (pl)
IS (1) IS7288A (pl)
MX (1) MXPA04005196A (pl)
NO (1) NO20042731L (pl)
PL (1) PL374558A1 (pl)
WO (1) WO2003045329A2 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002341991A1 (en) 2001-10-03 2003-04-14 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
CN1735620A (zh) * 2002-12-16 2006-02-15 兰贝克赛实验室有限公司 纯的左氧氟沙星半水合物和它的制备方法
KR100704641B1 (ko) * 2004-07-21 2007-04-06 주식회사유한양행 고순도의 레보플록사신 제조방법
JP2006273718A (ja) * 2005-03-28 2006-10-12 Shiono Chemical Co Ltd レボフロキサシン・１／２水和物の製法
CN1321121C (zh) * 2005-04-21 2007-06-13 浙江医药股份有限公司新昌制药厂 左氧氟沙星制备及后处理方法
US7964723B2 (en) 2008-08-02 2011-06-21 Apeloa-Kangyu And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
CN102070650B (zh) * 2011-01-28 2012-06-27 山东省药品检验所 左氧氟沙星-n-氧化物的制备方法
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
CN105823851A (zh) * 2015-12-15 2016-08-03 浙江海洋学院 一种检测海水中氧氟沙星对映体的方法
CN108218892A (zh) * 2018-03-16 2018-06-29 乐山职业技术学院 一种左氧氟沙星的纯化方法
CN112174981A (zh) * 2020-11-03 2021-01-05 深圳市祥根生物科技有限公司 一种左氧氟沙星脱氟杂质的制备方法
CN114507242B (zh) * 2022-01-26 2023-05-19 上虞京新药业有限公司 高光学纯度左氧氟沙星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170473B1 (da) * 1985-06-20 1995-09-11 Daiichi Seiyaku Co S(-)-pyridobenzoxazinforbindelser
US5237060A (en) * 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
TW208013B (pl) * 1990-03-01 1993-06-21 Daiichi Co Ltd
WO1994007873A1 (es) * 1992-10-07 1994-04-14 Derivados Del Etilo, S.A. Prodedimiento para la obtencion de benzoxazinas utiles para la sintesis de ofloxacina, levofloxacina y derivados
KR0125115B1 (ko) * 1994-03-22 1997-12-05 김은영 (-)피페라진 벤즈옥사진 유도체의 제조방법
KR100309871B1 (ko) * 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
AU2002341991A1 (en) * 2001-10-03 2003-04-14 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin

Also Published As

Publication number Publication date
HUP0500285A3 (en) 2009-03-30
IL162172A0 (en) 2005-11-20
EP1460997A2 (en) 2004-09-29
HRP20040546A2 (en) 2004-10-31
JP2005527484A (ja) 2005-09-15
PL374558A1 (pl) 2005-10-31
MXPA04005196A (es) 2005-11-23
EP1460997A4 (en) 2005-06-15
WO2003045329A2 (en) 2003-06-05
CN1596256A (zh) 2005-03-16
JP2008007517A (ja) 2008-01-17
IS7288A (is) 2004-06-21
HUP0500285A2 (hu) 2005-06-28
CA2466860A1 (en) 2003-06-05
JP2006219496A (ja) 2006-08-24
AU2002365416A1 (en) 2003-06-10
WO2003045329A3 (en) 2004-02-19

Similar Documents

Publication Publication Date Title
NO20042731L (no) Fremgangsmater for rensing av levofloxacin
WO2003028665A3 (en) Methods for the purification of levofloxacin
NO20061110L (no) Polymorfe former av rifaximin, fremgangsmater for deres fremstilling og anvendelse derav i medisinske preparater
NO20045699L (no) Bisindolyl-maleimidderivater som kinaseinhibitorer
DK1644395T3 (da) Fremgangsmåde til fremstilling af 4azido-nukleosidderivater
NO20055632L (no) Aromatiske oksyfenyl- og aromatiske sulfanylfenylderivater
NO20071579L (no) 4-Heteroarylmetylsubstituerte ftalazinonderivater
HRP20010776B1 (en) Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
NO301880B1 (no) Substituerte heterocykliske karboksylsyreamider og deres anvendelse for fremstilling av legemidler
HRP20041137B1 (hr) Indolni, azaindolni i srodni heterocikliäśni 4-alkenil piperidinski amidi
BR0307574A (pt) Derivados de nicotinamida úteis como inibidores de pde4
NO20001470D0 (no) Krystallisering med høy energitilførsel
HRP20010512B1 (en) Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
NO20031701L (no) Fremgangsmåte og mellomprodukter i fremstilling av 7- substituerte antiöstrogener
NO20051047L (no) Fremgangsmate og mellomprodukter for fremstilling av tienopyrrolderivater
BRPI0400375A (pt) Processo para remover vìrus em soluções de fibrinogênio para aplicação terapêutica e fibrinogênio obtido pelo dito processo
MY141020A (en) Novel pparalpha and ppargamma agonists
DK1404642T3 (da) Fremgangsmåde til fremstillimg af 7-amino-syn-3,5-dihydroxyheptansyrederivater, mellemprodukter derfor og fremgangsmåder til deres fremstilling
BRPI0212411B8 (pt) ' processos para reduzir os níveis de solventes orgânicos em um sólido de carbapenem, e para fabricar um hidrato cristalino'
DE60329189D1 (de) Pyrrolidinderivate als oxytocin antagonisten
ATE445619T1 (de) Pyridinylpyrazolopyrimidinon-derivate als pde 7 inhibitoren
HRP20040654B1 (hr) Postupak za pripravu derivata [1,4,5]-oksadiazepina
DE602004013644D1 (de) Kristalline alfuzosinbase
AR036735A1 (es) Derivados de 5-metoxi-8-aril-[1,2,4]triazolo[1,5-a]piridina
DK1559714T3 (da) Fremgangsmåde til fremstilling af 2-alkyl-3-aminothiophenderivater og 3-aminothiophenderivater

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application