PL374558A1 - Sposoby oczyszczania lewofloksacyny - Google Patents

Sposoby oczyszczania lewofloksacyny

Info

Publication number
PL374558A1
PL374558A1 PL02374558A PL37455802A PL374558A1 PL 374558 A1 PL374558 A1 PL 374558A1 PL 02374558 A PL02374558 A PL 02374558A PL 37455802 A PL37455802 A PL 37455802A PL 374558 A1 PL374558 A1 PL 374558A1
Authority
PL
Poland
Prior art keywords
levofloxacin
purification
methods
Prior art date
Application number
PL02374558A
Other languages
English (en)
Inventor
Valerie Niddam-Hildesheim
Neomi Gershon
Eduard Schwartz
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/263,192 external-priority patent/US7629458B2/en
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of PL374558A1 publication Critical patent/PL374558A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
PL02374558A 2001-11-29 2002-11-27 Sposoby oczyszczania lewofloksacyny PL374558A1 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33431601P 2001-11-29 2001-11-29
US35493902P 2002-02-11 2002-02-11
US26296502A 2002-10-03 2002-10-03
US10/263,192 US7629458B2 (en) 2001-10-03 2002-10-03 Preparation of levofloxacin and hemihydrate thereof

Publications (1)

Publication Number Publication Date
PL374558A1 true PL374558A1 (pl) 2005-10-31

Family

ID=31892240

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02374558A PL374558A1 (pl) 2001-11-29 2002-11-27 Sposoby oczyszczania lewofloksacyny

Country Status (13)

Country Link
EP (1) EP1460997A4 (pl)
JP (3) JP2005527484A (pl)
CN (1) CN1596256A (pl)
AU (1) AU2002365416A1 (pl)
CA (1) CA2466860A1 (pl)
HR (1) HRP20040546A2 (pl)
HU (1) HUP0500285A3 (pl)
IL (1) IL162172A0 (pl)
IS (1) IS7288A (pl)
MX (1) MXPA04005196A (pl)
NO (1) NO20042731L (pl)
PL (1) PL374558A1 (pl)
WO (1) WO2003045329A2 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002341991A1 (en) 2001-10-03 2003-04-14 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
CN1735620A (zh) * 2002-12-16 2006-02-15 兰贝克赛实验室有限公司 纯的左氧氟沙星半水合物和它的制备方法
KR100704641B1 (ko) * 2004-07-21 2007-04-06 주식회사유한양행 고순도의 레보플록사신 제조방법
JP2006273718A (ja) * 2005-03-28 2006-10-12 Shiono Chemical Co Ltd レボフロキサシン・１／２水和物の製法
CN1321121C (zh) * 2005-04-21 2007-06-13 浙江医药股份有限公司新昌制药厂 左氧氟沙星制备及后处理方法
US7964723B2 (en) 2008-08-02 2011-06-21 Apeloa-Kangyu And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
CN102070650B (zh) * 2011-01-28 2012-06-27 山东省药品检验所 左氧氟沙星-n-氧化物的制备方法
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
CN105823851A (zh) * 2015-12-15 2016-08-03 浙江海洋学院 一种检测海水中氧氟沙星对映体的方法
CN108218892A (zh) * 2018-03-16 2018-06-29 乐山职业技术学院 一种左氧氟沙星的纯化方法
CN112174981A (zh) * 2020-11-03 2021-01-05 深圳市祥根生物科技有限公司 一种左氧氟沙星脱氟杂质的制备方法
CN114507242B (zh) * 2022-01-26 2023-05-19 上虞京新药业有限公司 高光学纯度左氧氟沙星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170473B1 (da) * 1985-06-20 1995-09-11 Daiichi Seiyaku Co S(-)-pyridobenzoxazinforbindelser
US5237060A (en) * 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
TW208013B (pl) * 1990-03-01 1993-06-21 Daiichi Co Ltd
WO1994007873A1 (es) * 1992-10-07 1994-04-14 Derivados Del Etilo, S.A. Prodedimiento para la obtencion de benzoxazinas utiles para la sintesis de ofloxacina, levofloxacina y derivados
KR0125115B1 (ko) * 1994-03-22 1997-12-05 김은영 (-)피페라진 벤즈옥사진 유도체의 제조방법
KR100309871B1 (ko) * 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
AU2002341991A1 (en) * 2001-10-03 2003-04-14 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin

Also Published As

Publication number Publication date
HUP0500285A3 (en) 2009-03-30
NO20042731L (no) 2004-06-29
IL162172A0 (en) 2005-11-20
EP1460997A2 (en) 2004-09-29
HRP20040546A2 (en) 2004-10-31
JP2005527484A (ja) 2005-09-15
MXPA04005196A (es) 2005-11-23
EP1460997A4 (en) 2005-06-15
WO2003045329A2 (en) 2003-06-05
CN1596256A (zh) 2005-03-16
JP2008007517A (ja) 2008-01-17
IS7288A (is) 2004-06-21
HUP0500285A2 (hu) 2005-06-28
CA2466860A1 (en) 2003-06-05
JP2006219496A (ja) 2006-08-24
AU2002365416A1 (en) 2003-06-10
WO2003045329A3 (en) 2004-02-19

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Legal Events

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