NO20043047L - Mellomprodukter for LHRH-antagonistsyntese, fremgangsmate for fremstilling derav og fremgangsmate for LHRH-antagonistfremstilling - Google Patents

Mellomprodukter for LHRH-antagonistsyntese, fremgangsmate for fremstilling derav og fremgangsmate for LHRH-antagonistfremstilling

Info

Publication number
NO20043047L
NO20043047L NO20043047A NO20043047A NO20043047L NO 20043047 L NO20043047 L NO 20043047L NO 20043047 A NO20043047 A NO 20043047A NO 20043047 A NO20043047 A NO 20043047A NO 20043047 L NO20043047 L NO 20043047L
Authority
NO
Norway
Prior art keywords
preparation
boc
lhrh antagonist
4clphe
3pal
Prior art date
Application number
NO20043047A
Other languages
English (en)
Other versions
NO330129B1 (no
Inventor
Jon H Rasmussen
Wolfgang O Wachs
Stefan Hansen
Jens Fomsgaard
Palle H Rasmussen
Original Assignee
Carlbiotech Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlbiotech Ltd As filed Critical Carlbiotech Ltd As
Publication of NO20043047L publication Critical patent/NO20043047L/no
Publication of NO330129B1 publication Critical patent/NO330129B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20043047A 2001-12-29 2004-07-16 Fremgangsmater for fremstilling av et tripeptid NO330129B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0104463A SE0104463D0 (sv) 2001-12-29 2001-12-29 Mellanprodukter för syntes af LHRH-antagonister, sätt att framställa dem och sätt för framställning av LHRH-antagonister
PCT/IB2002/005583 WO2003055902A1 (en) 2001-12-29 2002-12-23 Intermediates for lhrh antagonist synthesis, process for their production, and process for lhrh antagonist production

Publications (2)

Publication Number Publication Date
NO20043047L true NO20043047L (no) 2004-08-30
NO330129B1 NO330129B1 (no) 2011-02-21

Family

ID=20286557

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043047A NO330129B1 (no) 2001-12-29 2004-07-16 Fremgangsmater for fremstilling av et tripeptid

Country Status (21)

Country Link
US (2) US20050124788A1 (no)
EP (2) EP1630169B1 (no)
JP (1) JP4272529B2 (no)
KR (1) KR100844520B1 (no)
CN (1) CN1304417C (no)
AT (2) ATE342913T1 (no)
AU (1) AU2002348749B2 (no)
CA (1) CA2471723C (no)
CY (2) CY1107580T1 (no)
DE (2) DE60222189T2 (no)
DK (2) DK1630169T3 (no)
ES (2) ES2296050T3 (no)
IL (2) IL162788A0 (no)
NO (1) NO330129B1 (no)
NZ (1) NZ534245A (no)
PT (2) PT1465917E (no)
RU (1) RU2307125C2 (no)
SE (1) SE0104463D0 (no)
SI (1) SI1630169T1 (no)
WO (1) WO2003055902A1 (no)
ZA (1) ZA200405136B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4407322B2 (ja) 2004-03-09 2010-02-03 味の素株式会社 ペプチドの製造方法
CN101037472B (zh) * 2006-03-14 2013-03-27 中国人民解放军军事医学科学院毒物药物研究所 具有低组胺释放作用的促黄体生成素释放激素拮抗剂
TWI442932B (zh) 2008-02-11 2014-07-01 Ferring Int Ct Sa 以ＧｎＲＨ拮抗劑治療攝護腺癌的方法
WO2012055903A1 (en) * 2010-10-27 2012-05-03 Ferring B.V. Process for the manufacture of degarelix and its intermediates
EP2447276A1 (en) 2010-10-27 2012-05-02 Ferring B.V. Process for the manufacture of Degarelix and its intermediates
KR102140982B1 (ko) 2012-06-01 2020-08-05 훼링 비.브이. 데가렐릭스의 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098777A (en) * 1977-03-14 1978-07-04 Merck & Co., Inc. Process for the preparation of pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
SU1623166A1 (ru) * 1989-04-03 1994-02-15 Институт биоорганической химии АН БССР Нейтропептиды, обладающие поведенческой активностью
US5225598A (en) * 1990-03-30 1993-07-06 Union Carbide Chemicals & Plastics Technology Corporation Selective production of linear pentaethylenehexamine and hydroxyethyldiethylenetriamine
EP0540626A1 (en) * 1990-07-24 1993-05-12 Eastman Chemical Company Process for synthesizing peptides
US5710246A (en) * 1996-03-19 1998-01-20 Abbott Laboratories Process for intermediates for the synthesis of LHRH antagonists
AU4394897A (en) * 1996-10-30 1998-05-22 Pfizer Inc. Pyridone-fused azabicyclic- or cytisine derivatives, their preparation and the ir use in addiction therapy
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
DE19941248A1 (de) 1998-09-01 2000-03-02 Asta Medica Ag Peptide mit N-substituierten Glycingruppen sowie diese enthaltende Arzneimittel zur Behandlung hormonabhängiger Tumore

Also Published As

Publication number Publication date
PT1465917E (pt) 2007-01-31
SI1630169T1 (sl) 2008-04-30
DE60222189D1 (de) 2007-10-11
EP1630169A2 (en) 2006-03-01
US20080306242A1 (en) 2008-12-11
HK1075052A1 (en) 2005-12-02
JP4272529B2 (ja) 2009-06-03
RU2004119964A (ru) 2006-01-10
AU2002348749A1 (en) 2003-07-15
DE60215544D1 (de) 2006-11-30
CY1107580T1 (el) 2013-03-13
DK1465917T3 (da) 2007-02-19
DE60215544T2 (de) 2007-08-30
ES2296050T3 (es) 2008-04-16
CA2471723A1 (en) 2003-07-10
IL162788A0 (en) 2005-11-20
SE0104463D0 (sv) 2001-12-29
ATE371666T1 (de) 2007-09-15
ZA200405136B (en) 2005-07-27
CY1107025T1 (el) 2012-09-26
EP1630169A3 (en) 2006-03-15
US8173770B2 (en) 2012-05-08
EP1630169B1 (en) 2007-08-29
CN1304417C (zh) 2007-03-14
DK1630169T3 (da) 2008-01-02
CN1622954A (zh) 2005-06-01
PT1630169E (pt) 2007-12-06
EP1465917B1 (en) 2006-10-18
NO330129B1 (no) 2011-02-21
CA2471723C (en) 2011-02-15
ATE342913T1 (de) 2006-11-15
EP1465917A1 (en) 2004-10-13
ES2275012T3 (es) 2007-06-01
NZ534245A (en) 2007-05-31
IL162788A (en) 2010-12-30
US20050124788A1 (en) 2005-06-09
KR20040090965A (ko) 2004-10-27
RU2307125C2 (ru) 2007-09-27
AU2002348749B2 (en) 2008-09-04
KR100844520B1 (ko) 2008-07-08
WO2003055902A1 (en) 2003-07-10
DE60222189T2 (de) 2008-06-19
JP2005516962A (ja) 2005-06-09

Similar Documents

Publication Publication Date Title
CY1108295T1 (el) Παραγωγα μονοσακχαριτη αβερμεκτινης τα οποια εχουν παρασιτοκτονες ιδιοτητες
DE60234629D1 (de) Formoteroltartrat verfahren und polymorph
DK0902022T3 (da) Hidtil ukendte benzofuranonderivater og fremgangsmåde til deres fremstilling
CY1107580T1 (el) Ενδιαμεσα για συνθεση ανταγωνιστων lhrh, διαδικασια για τη παραγωγη τους, και διαδικασια για παραγωγη ανταγωνιστων lhrh
PL367298A1 (en) Process for the production of beraprost and its salts
IL157046A0 (en) Phthalic acid diamide, method for the production thereof and the use of the same as a pesticide
TR200400293T4 (tr) 9-dihidro-13-asetilbasatin III'e ait suda çözünebilir 9-dihidro-paklitaksel türevlerinin sentezi.
DK1347960T3 (da) Fremgangsmåde til fremstilling af (+/-) trans-4-p-fluorphenyl-3-hydromethyl-1-methylpiperidin
FR2844791B1 (fr) Procede de preparation diastereoselectif d'olefines par la reaction d'horner-wadsworth-emmons comprenant un ajout d'un agent sequestrant tris-(polyoxaalkyl)-amine
PL352455A1 (en) Method of obtaining midodrin hydrochloride
MXPA04000623A (es) Derivados de tetrahidropiridazina y su uso como pesticidas.
ITMI20020934A1 (it) Processo per la sintesi di benazepril cloridrato
MXPA05003881A (es) Preparacion de compuestos triazospiro.
TR200001161A2 (tr) 8-Siklopentil-6-etil-3-[ikame edilmiş]-5, 8-Dihidro-4H-1, 2, 3A, 7, 8-Pentaaza-As-Indasenlerin hazırlandığı işlem ve burada yararlı ara bağlar.
HUP0204401A2 (hu) Eljárás 2,6-diklórfenol-vegyületek előállítására
MXPA03010325A (es) Benzoilciclohexenonas substituidas y su uso como agentes herbicidas.
BR0207895A (pt) Processo para a preparação de citalopram
MXPA04004537A (es) Derivados de gabusectina, metodo para produccion de los mismos y uso de los mismos.
SI1572615T1 (sl) Postopek za sintezo peptidov ki vsebujejo hidroksi prolinsko substrukturo
TW200420552A (en) Dihydro-furan-2-one derivatives, their intermediates and methods of manufacture

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees