NO20043101L - Farmasoytiske blandinger av oralt aktive taxanderivater som har forsterket biotilgjenglighet - Google Patents
Farmasoytiske blandinger av oralt aktive taxanderivater som har forsterket biotilgjenglighetInfo
- Publication number
- NO20043101L NO20043101L NO20043101A NO20043101A NO20043101L NO 20043101 L NO20043101 L NO 20043101L NO 20043101 A NO20043101 A NO 20043101A NO 20043101 A NO20043101 A NO 20043101A NO 20043101 L NO20043101 L NO 20043101L
- Authority
- NO
- Norway
- Prior art keywords
- orally active
- enhanced bioavailability
- taxane derivatives
- pharmaceutical mixtures
- active taxane
- Prior art date
Links
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34288901P | 2001-12-20 | 2001-12-20 | |
| PCT/US2002/040127 WO2003053350A2 (en) | 2001-12-20 | 2002-12-12 | Pharmaceutical compositions of orally active taxane derivatives having enhanced bioavailability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20043101L true NO20043101L (no) | 2004-07-19 |
Family
ID=23343716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20043101A NO20043101L (no) | 2001-12-20 | 2004-07-19 | Farmasoytiske blandinger av oralt aktive taxanderivater som har forsterket biotilgjenglighet |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20030220391A1 (de) |
| EP (1) | EP1465618A2 (de) |
| JP (1) | JP2006501134A (de) |
| KR (1) | KR20040066921A (de) |
| CN (1) | CN1273130C (de) |
| AR (1) | AR037951A1 (de) |
| AU (1) | AU2002361701A1 (de) |
| BR (1) | BR0215184A (de) |
| CA (1) | CA2470826A1 (de) |
| GE (1) | GEP20063806B (de) |
| HR (1) | HRP20040545A2 (de) |
| HU (1) | HUP0500843A2 (de) |
| IL (1) | IL162118A0 (de) |
| IS (1) | IS7306A (de) |
| MX (1) | MXPA04005877A (de) |
| NO (1) | NO20043101L (de) |
| PE (1) | PE20030742A1 (de) |
| PL (1) | PL374283A1 (de) |
| RS (1) | RS52904A (de) |
| RU (1) | RU2004119557A (de) |
| TW (1) | TW200302086A (de) |
| UY (1) | UY27598A1 (de) |
| WO (1) | WO2003053350A2 (de) |
| ZA (1) | ZA200404584B (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050063940A1 (en) * | 2002-02-25 | 2005-03-24 | Sveinbjorn Gizurarson | Bioadhesive agent |
| US6855332B2 (en) * | 2002-07-03 | 2005-02-15 | Lyfjathroun Hf. | Absorption promoting agent |
| KR100533458B1 (ko) | 2002-07-20 | 2005-12-07 | 대화제약 주식회사 | 파클리탁셀의 가용화용 조성물 및 그의 제조 방법 |
| EP1498120A1 (de) * | 2003-07-18 | 2005-01-19 | Aventis Pharma S.A. | Halbfeste Formulierung für die orale Verabreichung des Taxols |
| EP1785416A3 (de) | 2003-09-25 | 2007-05-30 | Tapestry Pharmaceuticals, Inc. | 9, 10-Alpha, Alpha-OH-Taxan-Analogen und Herstellungsverfahren dafür |
| US20060088591A1 (en) * | 2004-10-22 | 2006-04-27 | Jinghua Yuan | Tablets from a poorly compressible substance |
| WO2006058121A1 (en) * | 2004-11-23 | 2006-06-01 | Bristol-Myers Squibb Company | Crystalline forms of 3'-tert-butyl-3'-n-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-n-debenzoyl-4-o-methoxycarbonyl-paclitaxel |
| US20090130163A1 (en) * | 2005-02-18 | 2009-05-21 | Abraxis Bio Scoence, Inc. | Drugs With Improved Hydrophobicity For Incorporation in Medical Devices |
| AU2012202903B2 (en) * | 2005-02-18 | 2014-12-11 | Abraxis Bioscience, Inc. | Drugs with improved hydrophobicity for incorporation in medical devices |
| JP5436856B2 (ja) * | 2005-07-15 | 2014-03-05 | アンジオケム インコーポレーティッド | 薬学的複合体における担体としてのアプロチニンポリペプチドの使用 |
| US20070015834A1 (en) * | 2005-07-18 | 2007-01-18 | Moshe Flashner-Barak | Formulations of fenofibrate containing PEG/Poloxamer |
| BRPI0615265A8 (pt) | 2005-08-31 | 2018-03-06 | Abraxis Bioscience Llc | composições compreendendo agentes farmacêuticos pouco hidrossoluíveis e agentes antimicrobianos |
| WO2007134354A1 (de) * | 2006-05-23 | 2007-11-29 | Ebewe Pharma Ges.M.B.H. Nfg. Kg | Pharmazeutische formulierung |
| US11786504B2 (en) | 2006-09-28 | 2023-10-17 | Tapestry Pharmaceuticals, Inc. | Taxane analogs for the treatment of brain cancer |
| WO2008121476A1 (en) | 2007-03-28 | 2008-10-09 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
| US11873308B2 (en) | 2006-11-06 | 2024-01-16 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
| EP1946747A1 (de) * | 2007-01-17 | 2008-07-23 | Sandoz AG | Taxanderivat enthaltende pharmazeutische Zusammensetzung von verbesserter Stabilität |
| WO2008109360A1 (en) * | 2007-02-28 | 2008-09-12 | Tapestry Pharmaceuticals, Inc | Taxane analogs for the treatment of brain cancer |
| MX2010002179A (es) * | 2007-08-24 | 2010-04-27 | Stichting Het Nl Kanker I | Composicion para el tratamiento de enfermedades neoplasicas. |
| US9089544B2 (en) * | 2007-08-24 | 2015-07-28 | Slotervaart Participaties Bv | Composition |
| RU2488393C2 (ru) * | 2007-11-12 | 2013-07-27 | Новартис Аг | Жидкие композиции, включающие валсартан |
| EP2077132A1 (de) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung |
| ES2344674B1 (es) | 2008-08-07 | 2011-06-29 | Gp Pharm, S.A. | Composicion farmaceutica inyectable de taxanos. |
| US8921314B2 (en) | 2008-10-15 | 2014-12-30 | Angiochem, Inc. | Conjugates of GLP-1 agonists and uses thereof |
| EP2414560B1 (de) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Verfahren zur beschichtung einer oberfläche eines bauteils |
| EP3508239B1 (de) | 2009-05-18 | 2020-12-23 | Boehringer Ingelheim International GmbH | Adapter, inhalationseinrichtung und zerstäuber |
| CN102038635A (zh) | 2009-10-23 | 2011-05-04 | 天津天士力集团有限公司 | 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法 |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| MX2012005961A (es) | 2009-11-25 | 2012-06-14 | Boehringer Ingelheim Int | Nebulizador. |
| JP5658268B2 (ja) | 2009-11-25 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| JP5874724B2 (ja) | 2010-06-24 | 2016-03-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| WO2012130757A1 (de) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| EP2777691A1 (de) * | 2013-03-14 | 2014-09-17 | Pharmachemie B.V. | Taxoid - Reinigung der flüssigen Hilfsstoffen |
| WO2015018904A1 (en) | 2013-08-09 | 2015-02-12 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2835146B1 (de) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Zerstäuber |
| MX383195B (es) | 2014-05-07 | 2025-03-13 | Boehringer Ingelheim Int | Recipiente, nebulizador y uso. |
| WO2015169430A1 (en) | 2014-05-07 | 2015-11-12 | Boehringer Ingelheim International Gmbh | Nebulizer |
| BR122022010094B1 (pt) | 2014-05-07 | 2023-10-03 | Boehringer Ingelheim International Gmbh | Dispositivo indicador e recipiente |
| CN103980232A (zh) * | 2014-06-05 | 2014-08-13 | 北京诺普德医药科技有限公司 | 10-乙酰基多西紫杉醇及其用途 |
| US10980892B2 (en) | 2015-06-15 | 2021-04-20 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| TWI715636B (zh) * | 2015-09-30 | 2021-01-11 | 香港商慧源香港創新有限公司 | 口服紫杉烷組合物及方法 |
| CN108066335B (zh) * | 2016-11-11 | 2020-02-21 | 北京康辰药业股份有限公司 | 一种含有紫杉醇或其类似物的药物组合物及其制备方法 |
| FR3113238B1 (fr) | 2020-08-05 | 2024-04-05 | Gattefosse Sas | Utilisation comme excipient, d’un melange de macrogolglyceride laurique et de polyethylene glycol |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| US5817321A (en) * | 1992-10-08 | 1998-10-06 | Supratek Pharma, Inc. | Biological agent compositions |
| ES2224200T3 (es) * | 1992-11-27 | 2005-03-01 | Mayne Pharma (Usa) Inc. | Composicion inyectable estable de paclitaxel. |
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| US6395770B1 (en) * | 1995-10-26 | 2002-05-28 | Baker Norton Pharmaceuticals, Inc. | Method and compositions for administering taxanes orally to human patients |
| US6964946B1 (en) * | 1995-10-26 | 2005-11-15 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
| US5977163A (en) * | 1996-03-12 | 1999-11-02 | Pg-Txl Company, L. P. | Water soluble paclitaxel prodrugs |
| CA2189916C (en) * | 1996-11-08 | 2001-01-16 | Parkash S. Gill | A new regime for paclitaxel in kaposi's sarcoma patients |
| US6515016B2 (en) * | 1996-12-02 | 2003-02-04 | Angiotech Pharmaceuticals, Inc. | Composition and methods of paclitaxel for treating psoriasis |
| US6495579B1 (en) * | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| US5980936A (en) * | 1997-08-07 | 1999-11-09 | Alliance Pharmaceutical Corp. | Multiple emulsions comprising a hydrophobic continuous phase |
| HUP0101457A3 (en) * | 1997-12-31 | 2003-01-28 | Bristol Myers Squibb Co | Antitumor 2-aroyl-4-acyl paclitaxel analogs and medicaments containing them , their intermediates and method for producing them |
| IL131217A0 (en) * | 1998-03-10 | 2001-01-28 | Napro Biotherapeutics Inc | Novel methods and compositions for delivery of taxanes |
| US6979456B1 (en) * | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| IL144976A0 (en) * | 1999-05-17 | 2002-06-30 | Bristol Myers Squibb Co | A process for the preparation of paclitaxel |
| DE60010476T2 (de) * | 1999-08-11 | 2005-04-14 | Bristol-Myers Squibb Co. | Verfahren zur Herstellung eines C-4-Methylcarbonat-Analogons von Paclitaxel |
| US6136846A (en) * | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| US6750246B1 (en) * | 2000-02-03 | 2004-06-15 | Bristol-Myers Squibb Company | C-4 carbonate taxanes |
| US6916942B2 (en) * | 2000-02-03 | 2005-07-12 | Bristol-Myers Squibb Company | Process for the preparation of C-4 carbonate taxanes |
| TWI310684B (en) * | 2000-03-27 | 2009-06-11 | Bristol Myers Squibb Co | Synergistic pharmaceutical kits for treating cancer |
| EP1337273A2 (de) * | 2000-11-28 | 2003-08-27 | Transform Pharmaceuticals, Inc. | Pharmazeutische zusammensetzungen enthaltend paclitaxel, dessen derivate und dessen pharmazeutisch denkbare saltze |
| TWI297335B (en) * | 2001-07-10 | 2008-06-01 | Synta Pharmaceuticals Corp | Taxol enhancer compounds |
| AU2002357012A1 (en) * | 2001-11-27 | 2003-06-10 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
-
2002
- 2002-12-12 EP EP02797339A patent/EP1465618A2/de not_active Withdrawn
- 2002-12-12 AU AU2002361701A patent/AU2002361701A1/en not_active Abandoned
- 2002-12-12 BR BRPI0215184-7A patent/BR0215184A/pt not_active IP Right Cessation
- 2002-12-12 RU RU2004119557/15A patent/RU2004119557A/ru not_active Application Discontinuation
- 2002-12-12 CA CA002470826A patent/CA2470826A1/en not_active Abandoned
- 2002-12-12 HR HR20040545A patent/HRP20040545A2/xx not_active Application Discontinuation
- 2002-12-12 IL IL16211802A patent/IL162118A0/xx unknown
- 2002-12-12 GE GE5614A patent/GEP20063806B/en unknown
- 2002-12-12 CN CNB028254708A patent/CN1273130C/zh not_active Expired - Fee Related
- 2002-12-12 RS YU52904A patent/RS52904A/sr unknown
- 2002-12-12 WO PCT/US2002/040127 patent/WO2003053350A2/en not_active Ceased
- 2002-12-12 KR KR10-2004-7009593A patent/KR20040066921A/ko not_active Withdrawn
- 2002-12-12 HU HU0500843A patent/HUP0500843A2/hu unknown
- 2002-12-12 PL PL02374283A patent/PL374283A1/xx not_active Application Discontinuation
- 2002-12-12 JP JP2003554110A patent/JP2006501134A/ja not_active Withdrawn
- 2002-12-16 TW TW091136275A patent/TW200302086A/zh unknown
- 2002-12-19 US US10/323,551 patent/US20030220391A1/en not_active Abandoned
- 2002-12-19 AR ARP020105039A patent/AR037951A1/es unknown
- 2002-12-20 UY UY27598A patent/UY27598A1/es not_active Application Discontinuation
-
2003
- 2003-01-06 PE PE2003000013A patent/PE20030742A1/es not_active Application Discontinuation
-
2004
- 2004-06-09 ZA ZA200404584A patent/ZA200404584B/en unknown
- 2004-06-10 IS IS7306A patent/IS7306A/is unknown
- 2004-06-16 MX MXPA04005877A patent/MXPA04005877A/es unknown
- 2004-07-19 NO NO20043101A patent/NO20043101L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002361701A1 (en) | 2003-07-09 |
| ZA200404584B (en) | 2005-09-13 |
| CA2470826A1 (en) | 2003-07-03 |
| IS7306A (is) | 2004-06-10 |
| RU2004119557A (ru) | 2005-04-20 |
| HUP0500843A2 (hu) | 2005-12-28 |
| WO2003053350A2 (en) | 2003-07-03 |
| PL374283A1 (en) | 2005-10-03 |
| HRP20040545A2 (en) | 2005-08-31 |
| KR20040066921A (ko) | 2004-07-27 |
| CN1606437A (zh) | 2005-04-13 |
| UY27598A1 (es) | 2003-07-31 |
| PE20030742A1 (es) | 2003-09-02 |
| RS52904A (sr) | 2006-12-15 |
| WO2003053350A3 (en) | 2004-01-15 |
| TW200302086A (en) | 2003-08-01 |
| MXPA04005877A (es) | 2004-09-13 |
| GEP20063806B (en) | 2006-04-25 |
| AR037951A1 (es) | 2004-12-22 |
| JP2006501134A (ja) | 2006-01-12 |
| BR0215184A (pt) | 2006-06-06 |
| CN1273130C (zh) | 2006-09-06 |
| US20030220391A1 (en) | 2003-11-27 |
| EP1465618A2 (de) | 2004-10-13 |
| IL162118A0 (en) | 2005-11-20 |
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