NO20043244L - Meget folsom og kontinuerlig protein-tyrosin-fosfatase (PTPASE) test ved anvendelse av 6,8-difluor-4-metyl-umbelliferylfosfat (DiFMUP) - Google Patents

Meget folsom og kontinuerlig protein-tyrosin-fosfatase (PTPASE) test ved anvendelse av 6,8-difluor-4-metyl-umbelliferylfosfat (DiFMUP)

Info

Publication number
NO20043244L
NO20043244L NO20043244A NO20043244A NO20043244L NO 20043244 L NO20043244 L NO 20043244L NO 20043244 A NO20043244 A NO 20043244A NO 20043244 A NO20043244 A NO 20043244A NO 20043244 L NO20043244 L NO 20043244L
Authority
NO
Norway
Prior art keywords
difmup
ptpase
difluoro
test
highly sensitive
Prior art date
Application number
NO20043244A
Other languages
English (en)
Norwegian (no)
Inventor
Stefan Petry
Stefan Welte
Norbert Tennagels
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2002100173 external-priority patent/DE10200173A1/de
Priority claimed from DE2002136329 external-priority patent/DE10236329A1/de
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of NO20043244L publication Critical patent/NO20043244L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20043244A 2002-01-04 2004-08-02 Meget folsom og kontinuerlig protein-tyrosin-fosfatase (PTPASE) test ved anvendelse av 6,8-difluor-4-metyl-umbelliferylfosfat (DiFMUP) NO20043244L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2002100173 DE10200173A1 (de) 2002-01-04 2002-01-04 Ein hochsensitiver und kontinuerlicher Protein Tyrosin-Phosphatase (PTPase) Test unter Verwendung von 6,8 Difluoro-4-methyl-umbelliferylphosphat (DiFMUP)
DE2002136329 DE10236329A1 (de) 2002-08-08 2002-08-08 Ein hochsensitiver und kontinuierlicher Protein Tyrosin-Phosphatase (PTPase) Test unter Verwendung von 6,8 Difluoro-4-methyl-umbelliferylphosphat (DiFMUP)
PCT/EP2002/014755 WO2003056029A2 (fr) 2002-01-04 2002-12-24 Test de detection a haute sensibilite et en continu d'une proteine tyrosine phosphatase (ptpase) au moyen de 6,8-difluoro-4-methyl-ombelliferylphosphate

Publications (1)

Publication Number Publication Date
NO20043244L true NO20043244L (no) 2004-08-02

Family

ID=26010898

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043244A NO20043244L (no) 2002-01-04 2004-08-02 Meget folsom og kontinuerlig protein-tyrosin-fosfatase (PTPASE) test ved anvendelse av 6,8-difluor-4-metyl-umbelliferylfosfat (DiFMUP)

Country Status (12)

Country Link
EP (1) EP1466009A2 (fr)
JP (1) JP2005512600A (fr)
KR (1) KR20040073539A (fr)
CN (1) CN1612939A (fr)
AU (1) AU2002361217A1 (fr)
BR (1) BR0215452A (fr)
CA (1) CA2471601A1 (fr)
IL (1) IL162832A0 (fr)
MX (1) MXPA04006361A (fr)
NO (1) NO20043244L (fr)
RU (1) RU2004123794A (fr)
WO (1) WO2003056029A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100350045C (zh) * 2003-08-21 2007-11-21 北京农业生物技术研究中心 玉米酪氨酸蛋白磷酸酶基因及其编码蛋白与应用
US8008035B2 (en) 2007-01-25 2011-08-30 Roche Diagnostics Operations, Inc. Enhancement of vanadium-containing phosphatase inhibitors
EP1949894B1 (fr) * 2007-01-25 2016-06-29 Roche Diagnostics GmbH Amélioration des inhibiteurs de phosphatase contenant du vanadium avec des polyols
CN113155787A (zh) * 2020-12-29 2021-07-23 武汉合研生物医药科技有限公司 一种突变酶shp2 e76k的活性检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002516305A (ja) * 1998-05-12 2002-06-04 アメリカン・ホーム・プロダクツ・コーポレイション インスリン抵抗性および高血糖症の治療に有用な２，３，５−置換ビフェニル

Also Published As

Publication number Publication date
MXPA04006361A (es) 2004-10-04
IL162832A0 (en) 2005-11-20
CN1612939A (zh) 2005-05-04
RU2004123794A (ru) 2005-04-20
BR0215452A (pt) 2004-11-23
CA2471601A1 (fr) 2003-07-10
WO2003056029A3 (fr) 2004-04-01
KR20040073539A (ko) 2004-08-19
JP2005512600A (ja) 2005-05-12
AU2002361217A1 (en) 2003-07-15
WO2003056029A2 (fr) 2003-07-10
EP1466009A2 (fr) 2004-10-13

Similar Documents

Publication Publication Date Title
EP1377587A4 (fr) Inhibiteurs de proteine phosphate
ATA66497A (de) Sensor zur bestimmung eines enzymsubstrates
NO983278L (no) System for inspeksjon og evaluering av utstyr, system for administrering av
EP1444204A4 (fr) Inhibiteurs de proteines kinases et de proteines phosphatases, methodes d'identification et methodes d'utilisation associees
NO20004219D0 (no) Inhibitorer av fosfolipaseenzymer
NO20004220L (no) Inhibitorer av fosfolipaseenzymer
EP1109543A4 (fr) Inhibiteurs de la phosphodiesterase nitroses et nitrosyles, compositions et methodes d'utilisation
NO20004550D0 (no) Enzyminhibitorer
ATE288424T1 (de) Diaminothiazole und ihre verwendung zur inhibierung von proteinkinasen
DK1022334T3 (da) Hidtil ukendte amylaser
DE60218695D1 (de) Biosensoren und messverfahren
DK1131416T3 (da) Lipolytiske enzymvarianter
DE69932757D1 (de) System für MRI-gesteuerte Kryochirurgie
NO20004217D0 (no) Inhibitorer av fosfolipase A2
DE69933160D1 (de) Hochfrequenzverstärker
FI20011877L (fi) Menetelmä ja bioanturi analyysiä varten
DE69807845D1 (de) Sulfamide-metalloprotease inhibitoren
IS5553A (is) Kínólón sem serínprótínkljúfatálmar
DE69916716D1 (de) Polarimeter und zugehöriges messverfahren
FI20020176A0 (fi) Menetelmõ ja reagenssipakkaus geneettisen yhtõlõisyyden osoittamiseksi
AU2003270037A1 (en) Methods for measuring kinase activity and phosphatase activity
DK1456404T3 (da) Fremgangsmåde til at bestemme difibrotids biologiske aktivitet
EP1539134A4 (fr) Inhibiteurs selectifs de cyclooxigenase-2 nitroses et/ou nitrosyles, compositions et methodes d'utilisation
DK1047665T3 (da) Matrix metalloprotease inhibitorer
ID21607A (id) Metode produksi lempung aktif untuk pengolahan hidrokarbon aromatik

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application