RU2004123794A - Высокочувствительный и непрерывный тест на протеинтирозинфосфатазу при использовании 6,8-дифтор-4-метилумбеллиферилфостата - Google Patents
Высокочувствительный и непрерывный тест на протеинтирозинфосфатазу при использовании 6,8-дифтор-4-метилумбеллиферилфостата Download PDFInfo
- Publication number
- RU2004123794A RU2004123794A RU2004123794/15A RU2004123794A RU2004123794A RU 2004123794 A RU2004123794 A RU 2004123794A RU 2004123794/15 A RU2004123794/15 A RU 2004123794/15A RU 2004123794 A RU2004123794 A RU 2004123794A RU 2004123794 A RU2004123794 A RU 2004123794A
- Authority
- RU
- Russia
- Prior art keywords
- compound
- biological material
- difmup
- ptp
- difluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2002100173 DE10200173A1 (de) | 2002-01-04 | 2002-01-04 | Ein hochsensitiver und kontinuerlicher Protein Tyrosin-Phosphatase (PTPase) Test unter Verwendung von 6,8 Difluoro-4-methyl-umbelliferylphosphat (DiFMUP) |
| DE10200173.1 | 2002-01-04 | ||
| DE10236329.3 | 2002-08-08 | ||
| DE2002136329 DE10236329A1 (de) | 2002-08-08 | 2002-08-08 | Ein hochsensitiver und kontinuierlicher Protein Tyrosin-Phosphatase (PTPase) Test unter Verwendung von 6,8 Difluoro-4-methyl-umbelliferylphosphat (DiFMUP) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2004123794A true RU2004123794A (ru) | 2005-04-20 |
Family
ID=26010898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004123794/15A RU2004123794A (ru) | 2002-01-04 | 2002-12-24 | Высокочувствительный и непрерывный тест на протеинтирозинфосфатазу при использовании 6,8-дифтор-4-метилумбеллиферилфостата |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1466009A2 (fr) |
| JP (1) | JP2005512600A (fr) |
| KR (1) | KR20040073539A (fr) |
| CN (1) | CN1612939A (fr) |
| AU (1) | AU2002361217A1 (fr) |
| BR (1) | BR0215452A (fr) |
| CA (1) | CA2471601A1 (fr) |
| IL (1) | IL162832A0 (fr) |
| MX (1) | MXPA04006361A (fr) |
| NO (1) | NO20043244L (fr) |
| RU (1) | RU2004123794A (fr) |
| WO (1) | WO2003056029A2 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100350045C (zh) * | 2003-08-21 | 2007-11-21 | 北京农业生物技术研究中心 | 玉米酪氨酸蛋白磷酸酶基因及其编码蛋白与应用 |
| US8008035B2 (en) | 2007-01-25 | 2011-08-30 | Roche Diagnostics Operations, Inc. | Enhancement of vanadium-containing phosphatase inhibitors |
| EP1949894B1 (fr) * | 2007-01-25 | 2016-06-29 | Roche Diagnostics GmbH | Amélioration des inhibiteurs de phosphatase contenant du vanadium avec des polyols |
| CN113155787A (zh) * | 2020-12-29 | 2021-07-23 | 武汉合研生物医药科技有限公司 | 一种突变酶shp2 e76k的活性检测方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002516305A (ja) * | 1998-05-12 | 2002-06-04 | アメリカン・ホーム・プロダクツ・コーポレイション | インスリン抵抗性および高血糖症の治療に有用な２，３，５−置換ビフェニル |
-
2002
- 2002-12-24 IL IL16283202A patent/IL162832A0/xx unknown
- 2002-12-24 JP JP2003556546A patent/JP2005512600A/ja not_active Withdrawn
- 2002-12-24 MX MXPA04006361A patent/MXPA04006361A/es not_active Application Discontinuation
- 2002-12-24 BR BR0215452-8A patent/BR0215452A/pt not_active Application Discontinuation
- 2002-12-24 EP EP02796734A patent/EP1466009A2/fr not_active Withdrawn
- 2002-12-24 AU AU2002361217A patent/AU2002361217A1/en not_active Abandoned
- 2002-12-24 RU RU2004123794/15A patent/RU2004123794A/ru not_active Application Discontinuation
- 2002-12-24 WO PCT/EP2002/014755 patent/WO2003056029A2/fr not_active Ceased
- 2002-12-24 KR KR10-2004-7010451A patent/KR20040073539A/ko not_active Withdrawn
- 2002-12-24 CN CNA028266668A patent/CN1612939A/zh active Pending
- 2002-12-24 CA CA002471601A patent/CA2471601A1/fr not_active Abandoned
-
2004
- 2004-08-02 NO NO20043244A patent/NO20043244L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20043244L (no) | 2004-08-02 |
| MXPA04006361A (es) | 2004-10-04 |
| IL162832A0 (en) | 2005-11-20 |
| CN1612939A (zh) | 2005-05-04 |
| BR0215452A (pt) | 2004-11-23 |
| CA2471601A1 (fr) | 2003-07-10 |
| WO2003056029A3 (fr) | 2004-04-01 |
| KR20040073539A (ko) | 2004-08-19 |
| JP2005512600A (ja) | 2005-05-12 |
| AU2002361217A1 (en) | 2003-07-15 |
| WO2003056029A2 (fr) | 2003-07-10 |
| EP1466009A2 (fr) | 2004-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20060327 |