NO20043840L - Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma - Google Patents

Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma

Info

Publication number
NO20043840L
NO20043840L NO20043840A NO20043840A NO20043840L NO 20043840 L NO20043840 L NO 20043840L NO 20043840 A NO20043840 A NO 20043840A NO 20043840 A NO20043840 A NO 20043840A NO 20043840 L NO20043840 L NO 20043840L
Authority
NO
Norway
Prior art keywords
ifn
interleukin
gamma
stopping
immune reactions
Prior art date
Application number
NO20043840A
Other languages
Norwegian (no)
Inventor
Herbert Schneider
Wolfgang Halfbrodt
Thorsten Blume
Joachim Kuhnke
Ursula Monning
Wolf-Dietrich Doche
Bernd Elger
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20043840L publication Critical patent/NO20043840L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20043840A 2002-02-15 2004-09-14 Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma NO20043840L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10207843A DE10207843A1 (en) 2002-02-15 2002-02-15 Microlia inhibitors for interruption of interleukin 12 and IFN-gamma mediated immune responses
PCT/EP2003/000467 WO2003068225A1 (en) 2002-02-15 2003-01-17 Microglia inhibitors for interrupting immune reactions induced by interleukin 12 and ifn$g(g)

Publications (1)

Publication Number Publication Date
NO20043840L true NO20043840L (en) 2004-11-12

Family

ID=27674912

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043840A NO20043840L (en) 2002-02-15 2004-09-14 Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma

Country Status (21)

Country Link
EP (1) EP1474138A1 (en)
JP (1) JP2005522447A (en)
KR (1) KR20040084909A (en)
CN (1) CN1756546A (en)
AR (1) AR039556A1 (en)
AU (1) AU2003245523A1 (en)
BR (1) BR0307706A (en)
CA (1) CA2475770A1 (en)
DE (1) DE10207843A1 (en)
EC (1) ECSP045297A (en)
MX (1) MXPA04007943A (en)
NO (1) NO20043840L (en)
PE (1) PE20030906A1 (en)
PL (1) PL371327A1 (en)
RS (1) RS71304A (en)
RU (1) RU2004127677A (en)
TW (1) TW200306823A (en)
UA (1) UA81111C2 (en)
UY (1) UY27662A1 (en)
WO (1) WO2003068225A1 (en)
ZA (1) ZA200407382B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10207844A1 (en) * 2002-02-15 2003-09-04 Schering Ag 1-phenyl-2-heteroaryl-substituted benzimidazole derivatives, their use for the preparation of medicaments and pharmaceutical preparations containing these derivatives
WO2006097547A1 (en) * 2005-03-17 2006-09-21 Proyecto De Biomedicina Cima S.L. Use of 5'-methylthioadenosine (mta) in the prevention and/or treatment of autoimmune diseases and/or transplant rejection
US9550737B2 (en) * 2012-06-11 2017-01-24 Ucb Biopharma Sprl TNF -α modulating benzimidazoles
WO2016130501A1 (en) 2015-02-09 2016-08-18 Incyte Corporation Aza-heteroaryl compounds as pi3k-gamma inhibitors
RS63359B1 (en) 2015-11-06 2022-07-29 Incyte Corp HETEROCYCLIC COMPOUNDS AS PI3K-GAMA INHIBITORS
PT3390367T (en) * 2015-12-15 2020-09-23 Univ Leland Stanford Junior Method for preventing and/or treating aging-associated cognitive impairment and neuroinflammation
WO2017120194A1 (en) 2016-01-05 2017-07-13 Incyte Corporation Pyridine and pyridimine compounds as pi3k-gamma inhibitors
WO2017223414A1 (en) 2016-06-24 2017-12-28 Incyte Corporation HETEROCYCLIC COMPOUNDS AS PI3K-γ INHIBITORS
KR20240152947A (en) 2017-10-18 2024-10-22 인사이트 코포레이션 Condensed imidazole derivatives substituted by tertiary hydroxy groups as pi3k-gamma inhibitors
CR20250050A (en) 2018-09-05 2025-03-19 Incyte Corp Crystalline forms of a phosphoinositide 3-kinase (pi3k) inhibitor
JP7640458B2 (en) 2018-10-05 2025-03-05 アンナプルナ バイオ インコーポレイテッド Compounds and compositions for treating conditions associated with APJ receptor activity
CN112341451B (en) * 2019-08-09 2022-06-17 成都先导药物开发股份有限公司 Immunomodulator
CN112341450B (en) * 2019-08-09 2022-05-17 成都先导药物开发股份有限公司 Immunomodulator
CA3165339A1 (en) * 2019-12-19 2021-06-24 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Cd206 modulators their use and methods for preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330959A1 (en) * 1993-09-09 1995-03-16 Schering Ag New benzimidazole derivatives, processes for their preparation and their pharmaceutical use
SK287527B6 (en) * 2000-01-14 2011-01-04 Bayer Schering Pharma Aktiengesellschaft 1,2-Diarylbenzimidazoles and their pharmaceutical use
DE10134775A1 (en) * 2001-07-06 2003-01-30 Schering Ag 1-alkyl-2.aryl-benzimidazole derivatives, their use for the manufacture of medicaments and pharmaceutical preparations containing these derivatives
DE10135050A1 (en) * 2001-07-09 2003-02-06 Schering Ag 1-Ary1-2-N-, S- or O-substituted benzimidazole derivatives, their use for the preparation of medicaments and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
AR039556A1 (en) 2005-02-23
TW200306823A (en) 2003-12-01
JP2005522447A (en) 2005-07-28
WO2003068225A1 (en) 2003-08-21
RU2004127677A (en) 2005-06-10
MXPA04007943A (en) 2004-11-26
CN1756546A (en) 2006-04-05
BR0307706A (en) 2005-01-11
PE20030906A1 (en) 2004-01-17
UY27662A1 (en) 2003-09-30
CA2475770A1 (en) 2003-08-21
RS71304A (en) 2006-10-27
ZA200407382B (en) 2005-09-14
UA81111C2 (en) 2007-12-10
PL371327A1 (en) 2005-06-13
DE10207843A1 (en) 2003-09-04
KR20040084909A (en) 2004-10-06
EP1474138A1 (en) 2004-11-10
AU2003245523A1 (en) 2003-09-04
ECSP045297A (en) 2004-10-26

Similar Documents

Publication Publication Date Title
NO20044915L (en) C-aryl-glucoside SGLT2 inhibitors and method
DK1539115T3 (en) Methods and dosage forms for controlled delivery of paliperidone
DK1675279T3 (en) Method and device for synchronizing base stations
DK1606283T3 (en) P38 inhibitors and methods for their use
IS2675B (en) P38 inhibitors and methods for their use
NO20043840L (en) Microglia Inhibitors for Stopping Immune Reactions Induced by Interleukin-12 and IFN-Gamma
NO20052462D0 (en) Combination therapy using 1-amino cyclohexane derivatives and acetylcholinesterase inhibitors
IS7645A (en) Adjusts glucosterone receptor and method
DK2267930T3 (en) Method and device for retransmission
NO20052139L (en) Bandage and epidermal positioning mechanism and method of using the same
IS7090A (en) System, method and computer software for forming and purchasing medical devices
DK1532569T3 (en) Method and device for encoding objects
IS7594A (en) Laxofoxifene tablet and its coating
IS7726A (en) Pyrazolol pyridine and methods for their preparation and use
IS7655A (en) Method and system for automatic authorization of the licensee
ITMI20032401A1 (en) PROCEDURE AND DEVICE FOR THE OPERATION OF A
DK1344451T3 (en) Decor and set-up for an animal-related act
NO20043002L (en) Device and method for discontinuous polycondensation
ITRM20030236A1 (en) PROCEDURE AND APPARATUS FOR SIMULATION
IS7798A (en) Compounds, pharmaceutical preparations and methods
FI20020162L (en) Method and device for hot-gluing
DK1565574T3 (en) Product and method
IS7541A (en) Method and loading unit for distributing products
ITMI20030178A1 (en) APPARATUS AND FASTENING / RETAINING PROCEDURE
DK1426294T3 (en) Method and device for packaging flat articles

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application