NO20043850L - 10-(3-Cyklopropylaminometyl-1-pyrrolidinyl) pyridobenzo ksazinkarboksylsyrerederivater effektive mot medikament-resistente bakterier - Google Patents

10-(3-Cyklopropylaminometyl-1-pyrrolidinyl) pyridobenzo ksazinkarboksylsyrerederivater effektive mot medikament-resistente bakterier

Info

Publication number: NO20043850L
Authority: NO; Norway
Prior art keywords: group; hydrogen atom; resistant bacteria; kazazine; pyridobenzo
Prior art date: 2002-03-18

Application number

NO20043850A

Other languages

English (en)

Inventor

Yoshikazu Asahina

Masaya Takei

Original Assignee

Kyorin Seiyaku Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-18

Filing date

2004-09-14

Publication date

2004-09-14

2004-09-14 Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk

2004-09-14 Publication of NO20043850L publication Critical patent/NO20043850L/no

Links

-1 3-Cyclopropylaminomethyl-1-pyrrolidinyl Chemical group 0.000 title abstract 2
241000894006 Bacteria Species 0.000 title abstract 2
229940079593 drug Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
229910052731 fluorine Inorganic materials 0.000 abstract 3
125000001153 fluoro group Chemical group F* 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000004216 fluoromethyl group Chemical group [H]C([H])(F)* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
102100025142 Beta-microseminoprotein Human genes 0.000 abstract 1
241000192125 Firmicutes Species 0.000 abstract 1
101100185029 Homo sapiens MSMB gene Proteins 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
108020004999 messenger RNA Proteins 0.000 abstract 1
125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20043850A 2002-03-18 2004-09-14 10-(3-Cyklopropylaminometyl-1-pyrrolidinyl) pyridobenzo ksazinkarboksylsyrerederivater effektive mot medikament-resistente bakterier NO20043850L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2002074783		2002-03-18
JP2002369205		2002-12-20
PCT/JP2003/002967 WO2003078439A1 (en)	2002-03-18	2003-03-13	10-(3-cyclopropylaminomethyl-1-pyrrolidinyl)pyridobenzoxazinecarboxylic acid derivative effective against resistant bacterium

Publications (1)

Publication Number	Publication Date
NO20043850L true NO20043850L (no)	2004-09-14

Family

ID=28043757

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20043850A NO20043850L (no)	2002-03-18	2004-09-14	10-(3-Cyklopropylaminometyl-1-pyrrolidinyl) pyridobenzo ksazinkarboksylsyrerederivater effektive mot medikament-resistente bakterier

Country Status (14)

Country	Link
US (1)	US7153851B2 (no)
EP (1)	EP1486500B1 (no)
JP (1)	JP4468701B2 (no)
KR (1)	KR20040094806A (no)
CN (1)	CN1653071A (no)
AT (1)	ATE443064T1 (no)
AU (1)	AU2003213335B8 (no)
BR (1)	BR0308643A (no)
CA (1)	CA2478763A1 (no)
DE (1)	DE60329280D1 (no)
MX (1)	MXPA04009026A (no)
NO (1)	NO20043850L (no)
NZ (1)	NZ535182A (no)
WO (1)	WO2003078439A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN100410249C (zh)	2003-09-10	2008-08-13	杏林制药株式会社	7-(4-取代-3-环丙基氨基甲基-1-吡咯烷基)喹诺酮羧酸衍生物
NZ533360A (en) *	2004-06-04	2007-02-23	Ind Res Ltd	Improved method for preparing 3-hydroxy-4-hydroxymethyl-pyrrolidine compounds
JPWO2006009143A1 (ja) *	2004-07-21	2008-05-01	杏林製薬株式会社	（３ｓ）−３−ヒドロキシメチル−７−オキソピリドベンゾオキサジン−６−カルボン酸エステルの製造方法
GB0428250D0 (en) *	2004-12-23	2005-01-26	Novartis Ag	Organic compounds
EP1992613B1 (en)	2006-03-09	2013-01-30	Kyorin Pharmaceutical Co., Ltd.	Process for production of 3,4-disubstituted pyrrolidine derivative and intermediate for the production
NZ601080A (en) *	2010-01-08	2014-03-28	Kyorin Seiyaku Kk	Method for producing 3,4-disubstituted pyrrolidine derivative and production intermediate thereof
SG185619A1 (en) *	2010-05-31	2012-12-28	Kyorin Seiyaku Kk	Method for producing 3-substituted-4-fluoropyrrolidine derivative
AU2011321551A1 (en)	2010-10-25	2013-05-09	Kyorin Pharmaceutical Co., Ltd.	Method for producing 3,4-disubstituted pyrrolidine derivative
CN102276628A (zh) *	2011-06-21	2011-12-14	周崇科	氟喹诺酮类化合物及其合成方法
US9603804B2 (en)	2013-04-25	2017-03-28	Kyorin Pharmaceutical Co., Ltd.	Solid pharmaceutical composition
WO2016148066A1 (ja)	2015-03-13	2016-09-22	杏林製薬株式会社	呼吸器感染症治療剤
GB201708606D0 (en)	2017-05-30	2017-07-12	King S College London	Antibiotic resistance breakers
TW202415375A (zh) *	2017-06-16	2024-04-16	日商杏林製藥股份有限公司	吸入性肺炎、肺化膿症或肺膿瘍之治療劑
BR112022016941A2 (pt) *	2020-02-25	2022-10-25	Tes Pharma S R L	Compostos heterocíclicos para a modulação de nr2f6
CN112194667B (zh) *	2020-11-06	2021-08-17	湖南科技大学	取代1,4-苯并噁嗪并二氮卓类化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4822801A (en) *	1984-07-20	1989-04-18	Warner-Lambert Company	4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
JPS62155282A (ja) *	1985-12-27	1987-07-10	Sankyo Co Ltd	ピリドベンゾオキサジンカルボン酸誘導体
TW425394B (en) *	1996-04-24	2001-03-11	Daiichi Seiyaku Co	Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group
JPH10287669A (ja) *	1997-04-10	1998-10-27	Dai Ichi Seiyaku Co Ltd	置換アミノメチルピロリジン誘導体

2003
- 2003-03-13 EP EP03708575A patent/EP1486500B1/en not_active Expired - Lifetime
- 2003-03-13 WO PCT/JP2003/002967 patent/WO2003078439A1/ja not_active Ceased
- 2003-03-13 MX MXPA04009026A patent/MXPA04009026A/es active IP Right Grant
- 2003-03-13 US US10/508,154 patent/US7153851B2/en not_active Expired - Fee Related
- 2003-03-13 JP JP2003576444A patent/JP4468701B2/ja not_active Expired - Fee Related
- 2003-03-13 CA CA002478763A patent/CA2478763A1/en not_active Abandoned
- 2003-03-13 BR BR0308643-7A patent/BR0308643A/pt not_active IP Right Cessation
- 2003-03-13 NZ NZ535182A patent/NZ535182A/en unknown
- 2003-03-13 KR KR10-2004-7014519A patent/KR20040094806A/ko not_active Ceased
- 2003-03-13 DE DE60329280T patent/DE60329280D1/de not_active Expired - Lifetime
- 2003-03-13 AU AU2003213335A patent/AU2003213335B8/en not_active Ceased
- 2003-03-13 AT AT03708575T patent/ATE443064T1/de not_active IP Right Cessation
- 2003-03-13 CN CNA038113465A patent/CN1653071A/zh active Pending
2004
- 2004-09-14 NO NO20043850A patent/NO20043850L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2003213335B2 (en)	2008-09-11
JP4468701B2 (ja)	2010-05-26
US20050182052A1 (en)	2005-08-18
KR20040094806A (ko)	2004-11-10
EP1486500A1 (en)	2004-12-15
AU2003213335B8 (en)	2009-04-02
EP1486500B1 (en)	2009-09-16
JPWO2003078439A1 (ja)	2005-07-14
WO2003078439A1 (en)	2003-09-25
CA2478763A1 (en)	2003-09-25
EP1486500A4 (en)	2006-02-08
AU2003213335A1 (en)	2003-09-29
ATE443064T1 (de)	2009-10-15
US7153851B2 (en)	2006-12-26
NZ535182A (en)	2006-02-24
BR0308643A (pt)	2005-02-09
DE60329280D1 (de)	2009-10-29
CN1653071A (zh)	2005-08-10
MXPA04009026A (es)	2005-01-25

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Legal Events

Date	Code	Title	Description
2010-08-02	FC2A	Withdrawal, rejection or dismissal of laid open patent application