ATE420847T1 - Substituiertes phenylalkansäurederivat und dessen verwendung - Google Patents

Substituiertes phenylalkansäurederivat und dessen verwendung

Info

Publication number: ATE420847T1
Authority: AT; Austria
Prior art keywords: group; carbon atoms; alkyl group; substituted; phenylalkanic
Prior art date: 2002-02-21

Application number

AT03706983T

Other languages

English (en)

Inventor

Motoshi Shoda

Hiroshi Kuriyama

Original Assignee

Asahi Kasei Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-21

Filing date

2003-02-20

Publication date

2009-01-15

2003-02-20 Application filed by Asahi Kasei Pharma Corp filed Critical Asahi Kasei Pharma Corp

2009-01-15 Application granted granted Critical

2009-01-15 Publication of ATE420847T1 publication Critical patent/ATE420847T1/de

Links

239000002253 acid Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 2
125000006165 cyclic alkyl group Chemical group 0.000 abstract 2
125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
125000002619 bicyclic group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
150000002617 leukotrienes Chemical class 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1
230000000069 prophylactic effect Effects 0.000 abstract 1
150000003180 prostaglandins Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

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- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
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- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07—ORGANIC CHEMISTRY
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

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AT03706983T 2002-02-21 2003-02-20 Substituiertes phenylalkansäurederivat und dessen verwendung ATE420847T1 (de)

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JP2002045293		2002-02-21
JP2002301543		2002-10-16

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EP (1)	EP1477472B1 (de)
JP (3)	JP4390563B2 (de)
KR (1)	KR100938950B1 (de)
CN (1)	CN100387576C (de)
AT (1)	ATE420847T1 (de)
AU (1)	AU2003211384B2 (de)
CA (1)	CA2477208C (de)
DE (1)	DE60325830D1 (de)
DK (1)	DK1477472T3 (de)
ES (1)	ES2319753T3 (de)
MX (1)	MXPA04008176A (de)
PT (1)	PT1477472E (de)
WO (1)	WO2003070686A1 (de)

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EP1601251B1 (de) *	2003-02-13	2014-11-12	Wellstat Therapeutics Corporation	Verbindungen zur behandlung von stoffwechselstörungen
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EP1688138A4 (de) *	2003-11-26	2008-01-16	Takeda Pharmaceutical	Rezeptor-funktionsregulierendes mittel
EP1720855A4 (de) *	2004-03-02	2008-12-17	Smithkline Beecham Corp	Hemmer der akt aktivität
GB0409921D0 (en) *	2004-05-04	2004-06-09	Novartis Ag	Organic compounds
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WO2008139879A1 (ja) *	2007-04-26	2008-11-20	Pharmafrontier, Co., Ltd.	Ｇ蛋白質共役型レセプター抑制剤および医薬
ES2401557T3 (es) *	2007-08-02	2013-04-22	Amgen, Inc	Moduladores de Pl3 cinasas y métodos de uso
CA2712170C (en)	2008-01-18	2014-04-22	Asahi Kasei Pharma Corporation	Stable pharmaceutical composition
EP2272832A4 (de) *	2008-04-28	2011-09-07	Asahi Kasei Pharma Corp	Phenylpropionsäurederivat und seine verwendung
DK2292592T3 (da)	2008-06-05	2012-10-08	Asahi Kasei Pharma Corp	Sulfonamidforbindelse og anvendelse deraf
CN102391264A (zh) *	2011-09-21	2012-03-28	河北九派制药有限公司	6-溴咪唑并[1,2-a]吡啶的制备方法
JP5802518B2 (ja)	2011-10-31	2015-10-28	公益財団法人微生物化学研究会	新規化合物、その製造方法、及びその用途
US8889730B2 (en)	2012-04-10	2014-11-18	Pfizer Inc.	Indole and indazole compounds that activate AMPK
CA2905242C (en)	2013-03-15	2016-11-29	Pfizer Inc.	Indole compounds that activate ampk
CN105315167A (zh) *	2014-08-01	2016-02-10	华东师范大学	一种2,2,3-三芳基-3-芳基氨基丙酸甲酯衍生物及其合成方法和应用
CA2970011C (en)	2014-12-24	2021-08-03	Lg Chem, Ltd.	Biaryl derivative as gpr120 agonist
JP6635999B2 (ja) *	2017-10-13	2020-01-29	株式会社ダイセル	カリウム塩の製造方法、及びカリウム塩
CN110092774B (zh) *	2018-01-29	2022-04-08	中国科学院上海药物研究所	芳香丙酸类衍生物、及其制备方法和用途
US12252488B2 (en)	2021-02-12	2025-03-18	Nimbus Saturn, Inc.	HPK1 antagonists and uses thereof
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PT1477472E (pt) *	2002-02-21	2009-03-17	Asahi Kasei Pharma Corp	Derivado de ácido fenilalcanóico substituído e sua utilização

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JP4390563B2 (ja)	2009-12-24
MXPA04008176A (es)	2004-11-26
JP2009167217A (ja)	2009-07-30
AU2003211384B2 (en)	2008-12-11
DK1477472T3 (da)	2009-04-06
EP1477472B1 (de)	2009-01-14
KR100938950B1 (ko)	2010-01-26
CN100387576C (zh)	2008-05-14
EP1477472A1 (de)	2004-11-17
CA2477208A1 (en)	2003-08-28
ES2319753T3 (es)	2009-05-12
JPWO2003070686A1 (ja)	2005-06-09
CN1653032A (zh)	2005-08-10
DE60325830D1 (de)	2009-03-05
JP5000683B2 (ja)	2012-08-15
CA2477208C (en)	2010-11-30
JP5048017B2 (ja)	2012-10-17
HK1076445A1 (zh)	2006-01-20
KR20040094712A (ko)	2004-11-10
WO2003070686A1 (en)	2003-08-28
PT1477472E (pt)	2009-03-17
EP1477472A4 (de)	2005-12-14
AU2003211384A1 (en)	2003-09-09
JP2009167216A (ja)	2009-07-30

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EA200601847A1 (ru)	2007-04-27	Замещённые метиларил- или гетероариламидные соединения
EA200401282A1 (ru)	2005-02-24	Пиридиноилпиперидины как агонисты 5-ht1f
TW200604175A (en)	2006-02-01	Ortho substituted aryl or heteroaryl amide compounds
EA200301216A1 (ru)	2004-06-24	Замещенные хинуклидинами мультициклические гетероарилы для лечения заболевания
SE0201635D0 (sv)	2002-05-30	Novel compounds
CL2003002665A1 (es)	2005-01-14	COMPUESTOS DERIVADOS DE ACIDOS CARBOXILICOS, SUS SALES; PROCEDIMIENTO DE PREPARACION; COMPOSICION FARMACEUTICA, Y SU USO EN EL TRATAMIENTO DE ENFERMEDADES DONDE ES NECESARIO UN INHIBIDORE DEL FACTOR Xa Y /O UN INHIBIDOR DE SERINA PROTEASA.
MA29464B1 (fr)	2008-05-02	Methode de preparation d'acides 1,6-dihydro-6-oxo-4-pyrimidinecarboxyliques eventuellement 2-substitues
NO20091858L (no)	2009-07-08	Hydrobenzamid derivater som inhibitorer av HSP90
EP1394154A4 (de)	2005-05-18	Fünfgliedriges heterocyclisches alkansäurederivat
TW200635585A (en)	2006-10-16	Monocyclic substituted methanones
BG106219A (bg)	2002-08-30	Метод за получаване на чист циталопрам
ATE272617T1 (de)	2004-08-15	Sulfonamid-derivate
AU8811401A (en)	2002-04-02	Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient
EP1486500A4 (de)	2006-02-08	10-(3-cyclo propyl amino methyl-1-pyrrolidinyl) pyridobenzoxazin carbonsäure derivat mit wirkung gegen resistente bakterien
ES2106835T3 (es)	1997-11-16	Procedimiento de preparacion de alfa-ceto-amidas.
ATE428693T1 (de)	2009-05-15	Prostaglandinsynthese
DE602004019778D1 (de)	2009-04-16	Verwendung von 2-amino-1,3-propandiolderivaten zur herstellung eines medikaments zur behandlung von bestimmten schmerzen
ECSP014079A (es)	2002-02-25	Derivados de sulfonamida
WO2007092558A3 (en)	2007-12-27	Sulfonamide derivatives to treat infection with hepatitis c virus
EA200400656A1 (ru)	2004-10-28	Новые манделатные соли замещенных тетрациклических производных тетрагидрофурана
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TW200635911A (en)	2006-10-16	Sulfanyl substituted phenyl methanones