NO20050186L - Oligosakkaridbiomarkorer for mucopolysakkaridoser og andre beslektede forstyrrelser - Google Patents
Oligosakkaridbiomarkorer for mucopolysakkaridoser og andre beslektede forstyrrelserInfo
- Publication number
- NO20050186L NO20050186L NO20050186A NO20050186A NO20050186L NO 20050186 L NO20050186 L NO 20050186L NO 20050186 A NO20050186 A NO 20050186A NO 20050186 A NO20050186 A NO 20050186A NO 20050186 L NO20050186 L NO 20050186L
- Authority
- NO
- Norway
- Prior art keywords
- mps
- oligosaccharide
- target
- solution
- kit
- Prior art date
Links
- 229920001542 oligosaccharide Polymers 0.000 title abstract 5
- 150000002482 oligosaccharides Chemical class 0.000 title abstract 5
- 239000000090 biomarker Substances 0.000 title abstract 4
- 229920002683 Glycosaminoglycan Polymers 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000000243 solution Substances 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 238000012544 monitoring process Methods 0.000 abstract 2
- 238000002414 normal-phase solid-phase extraction Methods 0.000 abstract 2
- 208000002678 Mucopolysaccharidoses Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 239000012483 derivatization solution Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 206010028093 mucopolysaccharidosis Diseases 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
Foreliggende oppfinnelse vedrører fremgangsmåter for diagnostisering av mukopolysakkaridose ("MPS") og beslektede sykdommer. Denne oppfinnelsen vedrører fremgangsmåter for identifisering og kvantifisering av biokjemiske markører (biomarkører) som er til stede i biologiske væsker eller vev fra en pasient som har en MPS eller en beslektet forstyrrelse. Ett aspekt av fremgangsmåten omfatter bestemmelse av en målmengde av et mål-MPS-biomarkøroligosakkarid fra en biologisk målprøve tatt fra måldyret og deretter sammenligne rnålmengden med en referansemengde fra et referanse-MPS-biomarkøroligosakkarid for diagnostiseringen, karakteriseringen og overvåkningen av den kliniske behandlingen av MPS og beslektede sykdommer. Denne oppfinnelsen beskriver også et sett som omfatter en oligosakkaridderivatiseringsløsning, en syreløsning, en intem standard, en fastfaseekstraheringskolonne, en fastfaseekstraheringskolonne-vaskeløsning, en oligosakkaridelueringsløsning og et sett med instruksjoner som veileder i anvendelse av settet for å diagnostisere en MPS eller en beslektet sykdom.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPS2930A AUPS293002A0 (en) | 2002-06-14 | 2002-06-14 | Identification of oligosaccharides and their use in the diagnosis and evaluation of mucopolysaccharidoses and other related disorders |
| PCT/AU2003/000731 WO2003106997A1 (en) | 2002-06-14 | 2003-06-13 | Oligosaccharide biomarkers for mucopolysaccharidoses and other related disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20050186D0 NO20050186D0 (no) | 2005-01-13 |
| NO20050186L true NO20050186L (no) | 2005-03-10 |
Family
ID=3836492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20050186A NO20050186L (no) | 2002-06-14 | 2005-01-13 | Oligosakkaridbiomarkorer for mucopolysakkaridoser og andre beslektede forstyrrelser |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060286034A1 (no) |
| EP (2) | EP1532438B1 (no) |
| JP (1) | JP2005530157A (no) |
| AT (1) | ATE467834T1 (no) |
| AU (2) | AUPS293002A0 (no) |
| CA (1) | CA2488811A1 (no) |
| DE (1) | DE60332538D1 (no) |
| NO (1) | NO20050186L (no) |
| NZ (1) | NZ537512A (no) |
| TW (1) | TW200400351A (no) |
| WO (1) | WO2003106997A1 (no) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7951545B2 (en) | 2002-04-30 | 2011-05-31 | Seikagaku Corporation | Method for detecting lysosomal storage diseases |
| CA2524272A1 (en) | 2003-03-31 | 2004-10-14 | Women's And Children's Hospital | Multiplex screening for lysosomal storage disorders (lsds) |
| US20070134666A1 (en) * | 2003-10-27 | 2007-06-14 | Hiroshi Kasai | Simultneous analytical method for oxidatively damaged guanine compound and concentration correcting substance thereof, and analyzer used for this analytical method |
| JP2006047239A (ja) * | 2004-08-09 | 2006-02-16 | National Institute Of Advanced Industrial & Technology | 硫酸化単糖の同定方法及び硫酸化単糖異性体混合物の分析方法 |
| US20070161074A1 (en) * | 2005-12-27 | 2007-07-12 | Daiichi Pharmaceutical Co., Ltd. | Diagnostic method of mucopolysaccharidoses |
| CA2711590C (en) | 2008-01-18 | 2021-03-23 | Biomarin Pharmaceutical Inc. | Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof |
| JP2009229426A (ja) * | 2008-03-25 | 2009-10-08 | Sumitomo Bakelite Co Ltd | 糖鎖分析法 |
| CN102138069A (zh) * | 2008-07-23 | 2011-07-27 | P设备有限公司 | 便携式基于等离子体的诊断设备和诊断方法 |
| US8592140B2 (en) | 2009-01-02 | 2013-11-26 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
| US9029530B2 (en) * | 2009-01-02 | 2015-05-12 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
| US8809009B2 (en) | 2009-01-02 | 2014-08-19 | Biomarin Pharmaceutical Inc. | Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker |
| US8232073B2 (en) * | 2009-01-02 | 2012-07-31 | Zacharon Pharmaceuticals, Inc. | Quantification of non-reducing end glycan residual compounds |
| US20130121984A1 (en) * | 2011-11-07 | 2013-05-16 | Shire Human Genetic Therapies, Inc. | Biomarkers for sanfilippo syndrome and uses thereof |
| US9982288B2 (en) * | 2014-04-30 | 2018-05-29 | The Nemours Foundation | Mucopolysaccharidosis IVA/VII screening and treatment method |
| MA40954A (fr) * | 2014-11-14 | 2017-09-19 | Shire Human Genetic Therapies | Détermination de niveaux de glycosaminoglycane par spectrométrie de masse |
| CN107941963A (zh) * | 2017-12-29 | 2018-04-20 | 珍奥集团股份有限公司 | 一种增加骨密度保健食品中盐酸氨基葡萄糖与硫酸软骨素的含量测定方法 |
| CN116124971A (zh) * | 2018-08-07 | 2023-05-16 | 江苏双林海洋生物药业有限公司 | 农产品中氨基葡萄糖含量的检测方法 |
| CN108872441B (zh) * | 2018-08-14 | 2021-09-03 | 江苏康缘药业股份有限公司 | 一种测定氨基葡萄糖和硫酸软骨素的方法 |
| CN109781997A (zh) * | 2019-01-22 | 2019-05-21 | 中国人民解放军总医院 | 用于诊断粘多糖病ⅱ型的生物标志物及其应用 |
| CN114264741B (zh) * | 2021-12-15 | 2022-08-19 | 山东大学 | 一种鉴别猪来源肝素是否掺反刍类动物肝素的方法 |
| IT202200007808A1 (it) | 2022-04-20 | 2023-10-20 | Luigi Michele Pavone | Composizioni terapeutiche per malattie causate da accumulo di eparan solfato |
| CN115032377B (zh) * | 2022-08-11 | 2022-11-01 | 裕菁科技(上海)有限公司 | 一种粘多糖贮积症生物标记物及应用 |
| CN117304367B (zh) * | 2023-11-07 | 2025-12-12 | 中国海洋大学 | 岩藻糖化硫酸软骨素寡糖的衍生物及其制备方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310646A (en) * | 1988-05-13 | 1994-05-10 | Regents Of The University Of Minnesota | Method for the detection of mucopolysaccharide storage diseases |
| US5310464A (en) | 1991-01-04 | 1994-05-10 | Redepenning Jody G | Electrocrystallization of strongly adherent brushite coatings on prosthetic alloys |
| US6506384B1 (en) * | 1997-12-31 | 2003-01-14 | New York University | Early detection of mycobacterial disease |
| NZ337946A (en) * | 1998-09-25 | 2001-11-30 | Tokyo Gas Co Ltd | C-13 labelled oligosaccharides and polysaccharides useful as diagnostic agents for pancreatic exocrine function |
| RU2196988C2 (ru) * | 2000-04-19 | 2003-01-20 | Государственный новосибирский областной клинический диагностический центр | Способ диагностики мукополисахаридозов |
| BR0111473A (pt) * | 2000-06-07 | 2004-01-13 | Univ Duke | Métodos para triar um indivìduo quanto a uma doença de armazenagem de glicogênio, para triar um indivìduo quanto à doença de pompe, para monitorar a condição clìnica de um indivìduo com doença de pompe, para estimar a eficácia de um regime terapêutico em um indivìduo com doença de pompe e para determinar a concentração de um oligossacarìdeo em uma amostra biológica |
| GB0128498D0 (en) * | 2001-11-28 | 2002-01-23 | Inst Of Child Health | International standards for sphingolipids |
-
2002
- 2002-06-14 AU AUPS2930A patent/AUPS293002A0/en not_active Abandoned
-
2003
- 2003-06-13 EP EP03727020A patent/EP1532438B1/en not_active Expired - Lifetime
- 2003-06-13 EP EP09156934A patent/EP2081023A3/en not_active Ceased
- 2003-06-13 CA CA002488811A patent/CA2488811A1/en not_active Abandoned
- 2003-06-13 US US10/517,899 patent/US20060286034A1/en not_active Abandoned
- 2003-06-13 AU AU2003233255A patent/AU2003233255C1/en not_active Ceased
- 2003-06-13 NZ NZ537512A patent/NZ537512A/en not_active IP Right Cessation
- 2003-06-13 JP JP2004513765A patent/JP2005530157A/ja active Pending
- 2003-06-13 DE DE60332538T patent/DE60332538D1/de not_active Expired - Lifetime
- 2003-06-13 WO PCT/AU2003/000731 patent/WO2003106997A1/en not_active Ceased
- 2003-06-13 TW TW092116202A patent/TW200400351A/zh unknown
- 2003-06-13 AT AT03727020T patent/ATE467834T1/de not_active IP Right Cessation
-
2005
- 2005-01-13 NO NO20050186A patent/NO20050186L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1532438A1 (en) | 2005-05-25 |
| ATE467834T1 (de) | 2010-05-15 |
| US20060286034A1 (en) | 2006-12-21 |
| AU2003233255A1 (en) | 2003-12-31 |
| EP2081023A2 (en) | 2009-07-22 |
| EP2081023A3 (en) | 2009-10-07 |
| EP1532438B1 (en) | 2010-05-12 |
| AU2003233255C1 (en) | 2009-07-16 |
| WO2003106997A1 (en) | 2003-12-24 |
| NO20050186D0 (no) | 2005-01-13 |
| AUPS293002A0 (en) | 2002-07-04 |
| NZ537512A (en) | 2006-09-29 |
| AU2003233255B2 (en) | 2009-02-19 |
| EP1532438A4 (en) | 2006-12-06 |
| CA2488811A1 (en) | 2003-12-24 |
| DE60332538D1 (de) | 2010-06-24 |
| TW200400351A (en) | 2004-01-01 |
| JP2005530157A (ja) | 2005-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |