NO20052041L - Administrasjonsform for farmasoytisk aktive peptider med vedvarende frigivelse og fremgangsmate for fremstilling av denne - Google Patents

Administrasjonsform for farmasoytisk aktive peptider med vedvarende frigivelse og fremgangsmate for fremstilling av denne

Info

Publication number
NO20052041L
NO20052041L NO20052041A NO20052041A NO20052041L NO 20052041 L NO20052041 L NO 20052041L NO 20052041 A NO20052041 A NO 20052041A NO 20052041 A NO20052041 A NO 20052041A NO 20052041 L NO20052041 L NO 20052041L
Authority
NO
Norway
Prior art keywords
preparation
sustained release
administration
pharmaceutically active
active peptides
Prior art date
Application number
NO20052041A
Other languages
English (en)
Other versions
NO338309B1 (no
Inventor
Thomas Reissmann
Horst Bauer
Peter Romeis
Berthold Roessler
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10245525A external-priority patent/DE10245525A1/de
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of NO20052041L publication Critical patent/NO20052041L/no
Publication of NO338309B1 publication Critical patent/NO338309B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Oppfinnelsen er relatert til farmasøytiske administrasjonsformer med opprettholdt frigjøring omfattende minst ett farmakologisk aktivt peptid. Oppfinnelsen angår også en fremgangsmåte for fremstilling, et kit som omfatter et lyofilisert peptid og en vandig løsning av et uorganisk salt eller eddiksyresalt og anvendelse av en vandig løsning av et uorganisk eller eddiksyresalt for fremstilling av en farmasøytisk administrasjonsform som frigir peptider på en kontinuerlig måte over et lengre tidsrom.
NO20052041A 2002-09-27 2005-04-26 Farmasøytisk gel-preparat, fremgangsmåte for fremstilling og kitt, samt anvendelsen av det farmasøytiske gel-preparatet for fremstilling av et medikament NO338309B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41422502P 2002-09-27 2002-09-27
DE10245525A DE10245525A1 (de) 2002-09-27 2002-09-27 Darreichungsform für pharmazeutisch aktive Peptide mit anhaltender Wirkstofffreigabe (sustained release) und Verfahren zu deren Herstellung
DE10320051 2003-04-26
PCT/EP2003/010732 WO2004030650A2 (de) 2002-09-27 2003-09-26 Darreichungsform für pharmazeutisch aktive peptide mit anhaltender wirkstofffreigabe (sustained release) und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
NO20052041L true NO20052041L (no) 2005-06-10
NO338309B1 NO338309B1 (no) 2016-08-08

Family

ID=43646377

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052041A NO338309B1 (no) 2002-09-27 2005-04-26 Farmasøytisk gel-preparat, fremgangsmåte for fremstilling og kitt, samt anvendelsen av det farmasøytiske gel-preparatet for fremstilling av et medikament

Country Status (22)

Country Link
US (1) US7884071B2 (no)
EP (1) EP1565160B1 (no)
JP (1) JP4898118B2 (no)
KR (1) KR100633280B1 (no)
CN (1) CN100509053C (no)
AU (1) AU2003287950B2 (no)
BR (1) BRPI0314546B8 (no)
CA (1) CA2507524C (no)
DK (1) DK1565160T3 (no)
ES (1) ES2457019T3 (no)
HR (1) HRP20050371B1 (no)
IL (1) IL167415A (no)
IS (1) IS7750A (no)
ME (1) ME00509B (no)
MX (1) MXPA05003318A (no)
NO (1) NO338309B1 (no)
NZ (1) NZ538928A (no)
PL (1) PL208073B1 (no)
RS (2) RS20050247A (no)
RU (1) RU2333743C2 (no)
WO (1) WO2004030650A2 (no)
ZA (1) ZA200502150B (no)

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CN101534858A (zh) * 2006-01-05 2009-09-16 诺华有限公司 预防和治疗癌症转移和癌症转移相关性骨丢失的方法
US20070219811A1 (en) * 2006-03-16 2007-09-20 Kim John S Method for using an internet-based CRM application to create an on-line leads marketplace
EP1891964A1 (en) * 2006-08-08 2008-02-27 AEterna Zentaris GmbH Application of initial doses of LHRH analogues and maintenance doses of LHRH antagonists for the treatment of hormone-dependent cancers and corresponding pharmaceutical kits
AU2007339280B2 (en) * 2006-12-21 2013-12-05 Stryker Corporation Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
KR101863136B1 (ko) 2008-01-24 2018-05-31 에스퍼란스 파마슈티컬스, 인코포레이티드 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법
TWI539959B (zh) 2008-02-11 2016-07-01 菲瑞茵國際中心股份有限公司 治療轉移階段攝護腺癌的方法
US8324347B2 (en) * 2009-02-24 2012-12-04 Institute For Systems Biology Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry
MX2011011431A (es) * 2009-05-01 2012-02-23 Ferring Bv Composicion para el tratamiento de cancer de prostata.
PT2523653T (pt) 2010-01-13 2018-06-28 Ipsen Pharma Sas Processo para a preparação de composições farmacêuticas para a libertação prolongada de análogos de somatostatina
CN102204889B (zh) * 2011-05-23 2013-09-18 蚌埠丰原涂山制药有限公司 一种醋酸地加瑞克冻干粉针剂及其制备方法
PL4512390T1 (pl) 2012-06-01 2025-09-01 Ferring B.V. Wytwarzanie degareliksu
ITMI20121638A1 (it) * 2012-10-02 2014-04-03 Marco Sbracia Utilizzo di degarelix nel trattamento dell'endometriosi e di patologie ad essa correlate
IL238323B2 (en) 2012-10-30 2023-11-01 Esperance Pharmaceuticals Inc Antibody/drug conjugates and methods of use
TW201618783A (zh) 2014-08-07 2016-06-01 艾森塔製藥公司 以布魯頓(Bruton)氏酪胺酸激酶(BTK)佔據和BTK再合成速率為基礎之治療癌症、免疫和自體免疫疾病及發炎性疾病之方法
HUE058207T2 (hu) * 2017-01-31 2022-07-28 Veru Inc Készítmények és módszerek gonadotropin felszabadító hormon (GNRH) antagonisták elnyújtott idejû felszabadítására
US10994018B2 (en) * 2017-09-27 2021-05-04 Novel Pharma Inc. Long-acting palmitic acid-conjugated GnRH derivative, and pharmaceutical composition containing same
KR102408886B1 (ko) * 2018-01-31 2022-06-14 저장 산후아 클라이메이트 앤드 어플라이언스 컨트롤스 그룹 컴퍼니 리미티드 밸브 코어 조립체

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Also Published As

Publication number Publication date
BRPI0314546A8 (pt) 2015-12-15
ZA200502150B (en) 2005-11-30
IL167415A (en) 2014-05-28
JP4898118B2 (ja) 2012-03-14
AU2003287950A1 (en) 2004-04-23
BRPI0314546B8 (pt) 2021-05-25
US7884071B2 (en) 2011-02-08
ES2457019T3 (es) 2014-04-24
CN1684703A (zh) 2005-10-19
RU2005113163A (ru) 2005-10-10
CA2507524A1 (en) 2004-04-15
PL376446A1 (en) 2005-12-27
DK1565160T3 (da) 2014-04-28
NZ538928A (en) 2006-10-27
HRP20050371A2 (en) 2005-06-30
RU2333743C2 (ru) 2008-09-20
KR20050084829A (ko) 2005-08-29
US20050282731A1 (en) 2005-12-22
ME00509B (me) 2011-10-10
MXPA05003318A (es) 2005-09-12
RS20050247A (sr) 2007-06-04
HK1081855A1 (zh) 2006-05-26
BRPI0314546B1 (pt) 2020-04-07
CA2507524C (en) 2012-12-11
WO2004030650A2 (de) 2004-04-15
NO338309B1 (no) 2016-08-08
PL208073B1 (pl) 2011-03-31
IS7750A (is) 2005-03-17
KR100633280B1 (ko) 2006-10-16
BR0314546A (pt) 2005-08-09
EP1565160A2 (de) 2005-08-24
HRP20050371B1 (hr) 2014-09-26
WO2004030650A3 (de) 2004-07-15
AU2003287950B2 (en) 2009-01-29
RS52966B (sr) 2014-02-28
CN100509053C (zh) 2009-07-08
JP2006505538A (ja) 2006-02-16
EP1565160B1 (de) 2014-01-22

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