NO20052476L - 2-alkyl-(2-amino-3-aryl-propionyl)-piperazinderivater og beslektede forbindelser som melanokortinreseptorligander for behandlingen av obesitet. - Google Patents

2-alkyl-(2-amino-3-aryl-propionyl)-piperazinderivater og beslektede forbindelser som melanokortinreseptorligander for behandlingen av obesitet.

Info

Publication number: NO20052476L
Authority: NO; Norway
Prior art keywords: alkyl; butyl; group; propionyl; obesity
Prior art date: 2002-10-23

Application number

NO20052476A

Other languages

English (en)

Norwegian (no)

Other versions

NO20052476D0 (no

Inventor

Frank Hallock Ebetino

Anny-Odile Colson

Xinrong Tian

Wieslaw Adam Mazur

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-23

Filing date

2005-05-23

Publication date

2005-05-23

2005-05-23 Application filed by Procter & Gamble filed Critical Procter & Gamble

2005-05-23 Publication of NO20052476D0 publication Critical patent/NO20052476D0/no

2005-05-23 Publication of NO20052476L publication Critical patent/NO20052476L/no

Links

150000001875 compounds Chemical class 0.000 title abstract 2
102000004378 Melanocortin Receptors Human genes 0.000 title 1
108090000950 Melanocortin Receptors Proteins 0.000 title 1
208000008589 Obesity Diseases 0.000 title 1
239000003446 ligand Substances 0.000 title 1
235000020824 obesity Nutrition 0.000 title 1
229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
-1 (so-propyl Chemical group 0.000 abstract 5
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004974 2-butenyl group Chemical group C(C=CC)* 0.000 abstract 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
125000001494 2-propynyl group Chemical group [H]C#CC([H])([H])* 0.000 abstract 1
125000004211 3,5-difluorophenyl group Chemical group [H]C1=C(F)C([H])=C(*)C([H])=C1F 0.000 abstract 1
125000004180 3-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(F)=C1[H] 0.000 abstract 1
125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
125000004851 cyclopentylmethyl group Chemical group C1(CCCC1)C* 0.000 abstract 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
125000005394 methallyl group Chemical group 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1

Classifications

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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
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- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
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General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Neurology (AREA)
Obesity (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Gynecology & Obstetrics (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pregnancy & Childbirth (AREA)
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Psychiatry (AREA)
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NO20052476A 2002-10-23 2005-05-23 2-alkyl-(2-amino-3-aryl-propionyl)-piperazinderivater og beslektede forbindelser som melanokortinreseptorligander for behandlingen av obesitet. NO20052476L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US42057802P	2002-10-23	2002-10-23
PCT/US2003/033402 WO2004037797A2 (fr)	2002-10-23	2003-10-22	Ligands des recepteurs de la melanocortine

Publications (2)

Publication Number	Publication Date
NO20052476D0 NO20052476D0 (no)	2005-05-23
NO20052476L true NO20052476L (no)	2005-05-23

Family

ID=32176593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20052476A NO20052476L (no)	2002-10-23	2005-05-23	2-alkyl-(2-amino-3-aryl-propionyl)-piperazinderivater og beslektede forbindelser som melanokortinreseptorligander for behandlingen av obesitet.

Country Status (18)

Country	Link
US (2)	US7132539B2 (fr)
EP (1)	EP1556361A2 (fr)
JP (1)	JP2006506384A (fr)
KR (1)	KR20050072445A (fr)
CN (1)	CN1703221A (fr)
AR (1)	AR043054A1 (fr)
AU (1)	AU2003286557A1 (fr)
BR (1)	BR0315614A (fr)
CA (1)	CA2501231A1 (fr)
MA (1)	MA27478A1 (fr)
MX (1)	MXPA05004378A (fr)
NO (1)	NO20052476L (fr)
PE (1)	PE20040778A1 (fr)
PL (1)	PL376702A1 (fr)
RU (1)	RU2005111967A (fr)
TW (1)	TW200504033A (fr)
WO (1)	WO2004037797A2 (fr)
ZA (1)	ZA200502944B (fr)

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2003
- 2003-10-20 US US10/689,022 patent/US7132539B2/en not_active Expired - Fee Related
- 2003-10-20 TW TW092129035A patent/TW200504033A/zh unknown
- 2003-10-22 PL PL376702A patent/PL376702A1/pl not_active Application Discontinuation
- 2003-10-22 MX MXPA05004378A patent/MXPA05004378A/es unknown
- 2003-10-22 EP EP03777759A patent/EP1556361A2/fr not_active Withdrawn
- 2003-10-22 CA CA002501231A patent/CA2501231A1/fr not_active Abandoned
- 2003-10-22 AU AU2003286557A patent/AU2003286557A1/en not_active Abandoned
- 2003-10-22 WO PCT/US2003/033402 patent/WO2004037797A2/fr not_active Ceased
- 2003-10-22 BR BR0315614-1A patent/BR0315614A/pt not_active IP Right Cessation
- 2003-10-22 CN CNA2003801009342A patent/CN1703221A/zh active Pending
- 2003-10-22 RU RU2005111967/04A patent/RU2005111967A/ru not_active Application Discontinuation
- 2003-10-22 JP JP2004546990A patent/JP2006506384A/ja active Pending
- 2003-10-22 PE PE2003001070A patent/PE20040778A1/es not_active Application Discontinuation
- 2003-10-22 AR ARP030103859A patent/AR043054A1/es not_active Application Discontinuation
- 2003-10-22 KR KR1020057006836A patent/KR20050072445A/ko not_active Ceased
2005
- 2005-04-12 ZA ZA200502944A patent/ZA200502944B/en unknown
- 2005-04-25 MA MA28235A patent/MA27478A1/fr unknown
- 2005-05-23 NO NO20052476A patent/NO20052476L/no not_active Application Discontinuation
2006
- 2006-06-23 US US11/473,972 patent/US20060247224A1/en not_active Abandoned

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Publication number	Publication date
US20060247224A1 (en)	2006-11-02
BR0315614A (pt)	2005-08-30
CN1703221A (zh)	2005-11-30
PL376702A1 (pl)	2006-01-09
US7132539B2 (en)	2006-11-07
TW200504033A (en)	2005-02-01
JP2006506384A (ja)	2006-02-23
AR043054A1 (es)	2005-07-13
KR20050072445A (ko)	2005-07-11
EP1556361A2 (fr)	2005-07-27
WO2004037797A3 (fr)	2004-11-04
CA2501231A1 (fr)	2004-05-06
NO20052476D0 (no)	2005-05-23
US20050010031A1 (en)	2005-01-13
MA27478A1 (fr)	2005-08-01
WO2004037797A2 (fr)	2004-05-06
RU2005111967A (ru)	2006-01-20
ZA200502944B (en)	2006-02-22
PE20040778A1 (es)	2004-12-21
MXPA05004378A (es)	2005-07-05
AU2003286557A1 (en)	2004-05-13

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