NO20052479L - Tramadolformuleringer med forsinket frigjoring og 24 timers effektivitet - Google Patents
Tramadolformuleringer med forsinket frigjoring og 24 timers effektivitetInfo
- Publication number
- NO20052479L NO20052479L NO20052479A NO20052479A NO20052479L NO 20052479 L NO20052479 L NO 20052479L NO 20052479 A NO20052479 A NO 20052479A NO 20052479 A NO20052479 A NO 20052479A NO 20052479 L NO20052479 L NO 20052479L
- Authority
- NO
- Norway
- Prior art keywords
- delayed release
- release tramadol
- tramadol formulations
- hour efficacy
- efficacy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Det er beskrevet en opprettholdt frigjøringsttamadolformulering for oral administtering som etter initiell administtering av en dose tilveiebringer en analgetisk sammensetning irmen to timer, hvor den analgetiske virkningen fortsetter i minst 24 timer etter administtering.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28102602A | 2002-10-25 | 2002-10-25 | |
| US51037803P | 2003-10-10 | 2003-10-10 | |
| PCT/CA2003/001638 WO2004037222A2 (en) | 2002-10-25 | 2003-10-27 | Sustained-release tramadol formulations with 24-hour efficacy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20052479L true NO20052479L (no) | 2005-05-23 |
| NO20052479D0 NO20052479D0 (no) | 2005-05-23 |
Family
ID=32179487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052479A NO20052479D0 (no) | 2002-10-25 | 2005-05-23 | Tramadolformuleringer med forsinket frigjoring og 24 timers effektivitet |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JP2006507277A (no) |
| KR (1) | KR20050083816A (no) |
| AR (1) | AR045972A1 (no) |
| AU (1) | AU2003275855B2 (no) |
| CA (1) | CA2503155A1 (no) |
| IL (1) | IL168114A (no) |
| NO (1) | NO20052479D0 (no) |
| PT (1) | PT1594460E (no) |
| RU (1) | RU2328275C2 (no) |
| UA (1) | UA84277C2 (no) |
| WO (1) | WO2004037222A2 (no) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| TWI319713B (en) | 2002-10-25 | 2010-01-21 | Sustained-release tramadol formulations with 24-hour efficacy | |
| US8487002B2 (en) | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
| US7413749B2 (en) | 2003-03-11 | 2008-08-19 | Purdue Pharma L.P. | Titration dosing regimen for controlled release tramadol |
| EP1905435A3 (en) * | 2003-03-11 | 2008-05-14 | Euro-Celtique S.A. | Titration dosing regimen for controlled release tramadol |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| MXPA06013270A (es) * | 2004-05-14 | 2007-04-23 | Johnson & Johnson | Compuestos de opioide carboxamido. |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| WO2007048219A2 (en) | 2005-09-09 | 2007-05-03 | Labopharm Inc. | Sustained drug release composition |
| PT1931346E (pt) * | 2005-09-09 | 2012-08-14 | Angelini Labopharm Llc | Composição de trazodona para administração uma vez por dia |
| HUE029173T2 (hu) * | 2006-04-26 | 2017-02-28 | Alphapharm Pty Ltd | Szabályozott hatóanyag-leadású készítmények, amelyek tartalmaznak nem bevont diszkrét egység(ek)et és egy késleltetett hatóanyag-leadású mátrixot |
| CA2713128C (en) | 2008-01-25 | 2016-04-05 | Gruenenthal Gmbh | Pharmaceutical dosage form |
| AU2009243681B2 (en) | 2008-05-09 | 2013-12-19 | Grunenthal Gmbh | Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step |
| CN102046170B (zh) | 2008-05-27 | 2012-11-28 | 墨尔本大学 | 治疗患有咽鼓管功能障碍的哺乳动物的方法 |
| UA102706C2 (ru) * | 2008-10-27 | 2013-08-12 | Алза Корпорейшн | Лекарственная форма ацетаминофена и комплекса трамадола с замедленным действием для перорального приема |
| KR101738369B1 (ko) | 2009-07-22 | 2017-05-22 | 그뤼넨탈 게엠베하 | 핫 멜트 압출된 제어 방출 투여형 |
| CN102639118B (zh) | 2009-07-22 | 2015-07-29 | 格吕伦塔尔有限公司 | 氧化稳定的抗干扰剂型 |
| ES2606227T3 (es) | 2010-02-03 | 2017-03-23 | Grünenthal GmbH | Preparación de una composición farmacéutica en polvo mediante una extrusora |
| TWI516286B (zh) | 2010-09-02 | 2016-01-11 | 歌林達股份有限公司 | 含陰離子聚合物之抗破碎劑型 |
| BR112013005194A2 (pt) | 2010-09-02 | 2016-05-03 | Gruenenthal Gmbh | forma de dosagem resistente à violação compreendendo sal inorgânico |
| BR112014001091A2 (pt) | 2011-07-29 | 2017-02-14 | Gruenenthal Gmbh | comprimido resistente à adulteração que fornece liberação imediata do fármaco |
| EA201400172A1 (ru) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства |
| MX356421B (es) | 2012-02-28 | 2018-05-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico. |
| EP2838512B1 (en) | 2012-04-18 | 2018-08-22 | Grünenthal GmbH | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| US9737490B2 (en) | 2013-05-29 | 2017-08-22 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
| EP3003279A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
| BR112016000194A8 (pt) | 2013-07-12 | 2019-12-31 | Gruenenthal Gmbh | forma de dosagem resistente à violação contendo o polímero de acetato de etileno-vinila |
| EP3073994A1 (en) | 2013-11-26 | 2016-10-05 | Grünenthal GmbH | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
| WO2015173195A1 (en) | 2014-05-12 | 2015-11-19 | Grünenthal GmbH | Tamper resistant immediate release capsule formulation comprising tapentadol |
| EA201692388A1 (ru) | 2014-05-26 | 2017-05-31 | Грюненталь Гмбх | Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы |
| WO2016170097A1 (en) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
| JP2018526414A (ja) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
| WO2017192921A1 (en) | 2016-05-05 | 2017-11-09 | Monosol Rx, Llc | Enhanced delivery epinephrine compositions |
| BR112018072467A2 (pt) * | 2016-05-05 | 2019-02-19 | Aquestive Therapeutics, Inc. | composições farmacêuticas com permeação aumentada |
| US12465564B2 (en) | 2021-10-25 | 2025-11-11 | Aquestive Therapeutics, Inc. | Oral and nasal compositions and methods of treatment |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ260408A (en) * | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
| DE19530575A1 (de) * | 1995-08-19 | 1997-02-20 | Gruenenthal Gmbh | Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz |
| PT1009387E (pt) * | 1997-07-02 | 2006-08-31 | Euro Celtique Sa | Formulacoes estabilizadas de libertacao controlada de tramadol |
| DE10015479A1 (de) * | 2000-03-29 | 2001-10-11 | Basf Ag | Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität |
| US6607748B1 (en) * | 2000-06-29 | 2003-08-19 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
| DE10108122A1 (de) * | 2001-02-21 | 2002-10-02 | Gruenenthal Gmbh | Arzneimittel auf Basis von Tramadol |
-
2003
- 2003-10-27 KR KR1020057007089A patent/KR20050083816A/ko not_active Ceased
- 2003-10-27 WO PCT/CA2003/001638 patent/WO2004037222A2/en not_active Ceased
- 2003-10-27 AR ARP030103926A patent/AR045972A1/es unknown
- 2003-10-27 RU RU2005115855/15A patent/RU2328275C2/ru not_active IP Right Cessation
- 2003-10-27 CA CA002503155A patent/CA2503155A1/en not_active Abandoned
- 2003-10-27 PT PT03809237T patent/PT1594460E/pt unknown
- 2003-10-27 UA UAA200504852A patent/UA84277C2/ru unknown
- 2003-10-27 JP JP2004545655A patent/JP2006507277A/ja active Pending
- 2003-10-27 AU AU2003275855A patent/AU2003275855B2/en not_active Expired
-
2005
- 2005-04-19 IL IL168114A patent/IL168114A/en active IP Right Grant
- 2005-05-23 NO NO20052479A patent/NO20052479D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2328275C2 (ru) | 2008-07-10 |
| PT1594460E (pt) | 2008-06-27 |
| RU2005115855A (ru) | 2006-01-20 |
| AU2003275855A1 (en) | 2004-05-13 |
| KR20050083816A (ko) | 2005-08-26 |
| WO2004037222A2 (en) | 2004-05-06 |
| UA84277C2 (ru) | 2008-10-10 |
| IL168114A (en) | 2011-05-31 |
| NO20052479D0 (no) | 2005-05-23 |
| AR045972A1 (es) | 2005-11-23 |
| WO2004037222A3 (en) | 2005-09-22 |
| CA2503155A1 (en) | 2004-05-06 |
| JP2006507277A (ja) | 2006-03-02 |
| AU2003275855B2 (en) | 2009-04-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20052479L (no) | Tramadolformuleringer med forsinket frigjoring og 24 timers effektivitet | |
| NO20050379L (no) | Anvendelse av venlafaxinhydroklorid for fremstilling av en innkapslet forlenget frigjoringsblanding | |
| IL165264A (en) | Protein kinase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating protein kinase-associated diseases | |
| CY1105120T1 (el) | Η αντιμετωπιση αναπνευστικων νοσων | |
| BR0306870A (pt) | Composição farmacêutica oral, e, método para preparar a mesma | |
| NO20065638L (no) | Formuleringer med kontrollert frigivelse inneholdende vardenafil | |
| MXPA04009977A (es) | Formulaciones de tramadol de liberacion sostenida con eficacia clinica durante 24 horas. | |
| PL369108A1 (en) | 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | |
| UA84266C2 (uk) | Дозована лікарська форма у вигляді таблетки або пелети для перорального введення, яка містить інгібітор pde 4 та полівінілпіролідон, способи її одержання та застосування | |
| NO20062513L (no) | Sammensetninger og doseringsformer for forsterket absorpsjon av metformin | |
| ES2295609T3 (es) | Derivados de tiadiazolilpiperazina utiles para tratar o prevenir un dolor. | |
| NO20045486L (no) | Nye forbindelser og deres anvendelse | |
| CY1111470T1 (el) | Νεες φαρμακευτικες συνθεσεις που περιεχουν φλιβανσερινη πολυμορφη α | |
| NO20073405L (no) | Farmasoytisk utforming inneholdende en frigjoringshastighetskontrollerende sammensetning | |
| DE602005007339D1 (de) | Nebivolol und dessen pharmazeutisch unbedenkliche salze, herstellungsverfahren und pharmazeutische zusammensetzungen von nebivolol | |
| DK1572153T3 (da) | Fremstilling af sterile vandige suspensioner, som omfatter mikroniserede krystallinske virksomme stoffer til inhalering | |
| DK1594460T3 (da) | Tramadol-formuleringer med forlænget frigivelse og 24 timers effektivitet | |
| NO304113B1 (no) | Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament | |
| WO2004071374A3 (en) | Once a day orally administered pharmaceutical compositions | |
| EA200800783A1 (ru) | Композиция тразодона для введения один раз в день | |
| DK1228758T3 (da) | Anvendelse af sulfodehydroabietinsyre til behandling af inflammatorisk tarmsygdom | |
| NO20050771L (no) | Bicifadinformulering | |
| NO20014855D0 (no) | N-(2-fenyl-4-aminobutyl)-1-naftamider som neurokinin-1- reseptorantagonister | |
| MXPA05008843A (es) | Sistema terapeutico que comprende amoxicilina y acido clavulanico. | |
| BR0114395A (pt) | Composição farmacêutica para administração por suprimento via oral |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |