UA84277C2 - Композиция трамадола с пролонгированным высвобождением с 24-часовым действием - Google Patents

Композиция трамадола с пролонгированным высвобождением с 24-часовым действием

Info

Publication number: UA84277C2
Authority: UA; Ukraine
Prior art keywords: sustained; release tramadol; tramadol formulations; hour efficacy; efficacy
Prior art date: 2002-10-25

Application number

UAA200504852A

Other languages

English (en)

Russian (ru)

Ukrainian (uk)

Inventor

Венсан Ленар

Патрисия Лаура Оуаджи-Нджики

Джонатан Бейкон

Рашид Узеруру

Соня Жерве

Милу Рахмуни

Деймон Смит

Original Assignee

Лабофарм Инк.

Лабофарм Юроп Лимитед

Лабофарм (Барбадос) Лимитед

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-25

Filing date

2003-10-27

Publication date

2008-10-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32179487&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA84277(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-10-27 Application filed by Лабофарм Инк., Лабофарм Юроп Лимитед, Лабофарм (Барбадос) Лимитед filed Critical Лабофарм Инк.

2008-10-10 Publication of UA84277C2 publication Critical patent/UA84277C2/ru

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

UAA200504852A 2002-10-25 2003-10-27 Композиция трамадола с пролонгированным высвобождением с 24-часовым действием UA84277C2 (ru)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US28102602A	2002-10-25	2002-10-25
US51037803P	2003-10-10	2003-10-10
PCT/CA2003/001638 WO2004037222A2 (en)	2002-10-25	2003-10-27	Sustained-release tramadol formulations with 24-hour efficacy

Publications (1)

Publication Number	Publication Date
UA84277C2 true UA84277C2 (ru)	2008-10-10

Family

ID=32179487

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UAA200504852A UA84277C2 (ru)	2002-10-25	2003-10-27	Композиция трамадола с пролонгированным высвобождением с 24-часовым действием

Country Status (11)

Country	Link
JP (1)	JP2006507277A (no)
KR (1)	KR20050083816A (no)
AR (1)	AR045972A1 (no)
AU (1)	AU2003275855B2 (no)
CA (1)	CA2503155A1 (no)
IL (1)	IL168114A (no)
NO (1)	NO20052479L (no)
PT (1)	PT1594460E (no)
RU (1)	RU2328275C2 (no)
UA (1)	UA84277C2 (no)
WO (1)	WO2004037222A2 (no)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
TWI319713B (en)	2002-10-25	2010-01-21		Sustained-release tramadol formulations with 24-hour efficacy
US8487002B2 (en)	2002-10-25	2013-07-16	Paladin Labs Inc.	Controlled-release compositions
EP1905435A3 (en) *	2003-03-11	2008-05-14	Euro-Celtique S.A.	Titration dosing regimen for controlled release tramadol
US7413749B2 (en) *	2003-03-11	2008-08-19	Purdue Pharma L.P.	Titration dosing regimen for controlled release tramadol
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
ES2485867T3 (es) *	2004-05-14	2014-08-14	Janssen Pharmaceutica Nv	Compuestos opioides de carboxamido
DE102004032049A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
EA014739B1 (ru) *	2005-09-09	2011-02-28	Лабофарм Инк.	Композиция тразодона для введения один раз в день
RU2008113439A (ru)	2005-09-09	2009-10-20	Лабофарм Инк. (CA)	Композиции с замедленным высвобождением лекарственного средства
HUE029173T2 (hu) *	2006-04-26	2017-02-28	Alphapharm Pty Ltd	Szabályozott hatóanyag-leadású készítmények, amelyek tartalmaznak nem bevont diszkrét egység(ek)et és egy késleltetett hatóanyag-leadású mátrixot
CA2713128C (en)	2008-01-25	2016-04-05	Gruenenthal Gmbh	Pharmaceutical dosage form
BRPI0912014A2 (pt)	2008-05-09	2019-03-06	Grünenthal GmbH	processo para a preparação de uma formulação em pó intermediária e uma forma de dosagem sólida final sob uso de uma etapa de congelamento por atomização
BRPI0912126A2 (pt)	2008-05-27	2015-11-03	Univ Melbourne	método de tratamento de mamíferos com disfunções na trompa de eustáquio
CN107028908A (zh) *	2008-10-27	2017-08-11	阿尔扎公司	对乙酰氨基酚/曲马多口服延释剂型
RU2015138422A (ru)	2009-07-22	2018-12-25	Грюненталь Гмбх	Стабильная при окислении, прочная на излом лекарственная форма
CN102573805A (zh)	2009-07-22	2012-07-11	格吕伦塔尔有限公司	热熔挤出的控制释放剂型
US9579285B2 (en)	2010-02-03	2017-02-28	Gruenenthal Gmbh	Preparation of a powdery pharmaceutical composition by means of an extruder
NZ607392A (en)	2010-09-02	2015-03-27	Gruenenthal Chemie	Tamper resistant dosage form comprising inorganic salt
BR112013005234A2 (pt)	2010-09-02	2016-05-03	Gruenenthal Gmbh	forma de dosagem resistente à violação compreendendo um polímero aniônico.
PE20141638A1 (es)	2011-07-29	2014-11-22	Gruenenthal Chemie	Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato
RS56527B1 (sr)	2011-07-29	2018-02-28	Gruenenthal Gmbh	Tableta za trenutno oslobađanje leka rezistentna na zloupotrebu
MX356421B (es)	2012-02-28	2018-05-29	Gruenenthal Gmbh	Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
DK2838512T3 (en)	2012-04-18	2018-11-19	Gruenenthal Gmbh	MANIPULATED AND DOSAGE DUMPED PHARMACEUTICAL DOSAGE FORM
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
AR096439A1 (es)	2013-05-29	2015-12-30	Gruenenthal Gmbh	Forma de dosificación resistente al uso indebido que contiene una o más partículas
JP6445537B2 (ja)	2013-05-29	2018-12-26	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	１個または複数の粒子を含有する改変防止（ｔａｍｐｅｒ−ｒｅｓｉｓｔａｎｔ）剤形
US10624862B2 (en)	2013-07-12	2020-04-21	Grünenthal GmbH	Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
AU2014356581C1 (en)	2013-11-26	2020-05-28	Grunenthal Gmbh	Preparation of a powdery pharmaceutical composition by means of cryo-milling
MX2016014738A (es)	2014-05-12	2017-03-06	Gruenenthal Gmbh	Formulacion en capsula de liberacion inmediata resistente a alteraciones que comprende tapentadol.
MX2016015417A (es)	2014-05-26	2017-02-22	Gruenenthal Gmbh	Multiparticulas protegidas contra vertido de dosis etanolico.
JP2018517676A (ja)	2015-04-24	2018-07-05	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	即時放出および溶媒抽出に対する耐性を有する改変防止製剤
AU2016319203A1 (en)	2015-09-10	2018-02-22	Grünenthal GmbH	Protecting oral overdose with abuse deterrent immediate release formulations
JP7653218B2 (ja)	2016-05-05	2025-03-28	アクエスティブセラピューティクスインコーポレイテッド	送達増強エピネフリン組成物
EP3452024A1 (en) *	2016-05-05	2019-03-13	Aquestive Therapeutics, Inc.	Pharmaceutical compositions with enhanced permeation
US12465564B2 (en)	2021-10-25	2025-11-11	Aquestive Therapeutics, Inc.	Oral and nasal compositions and methods of treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ260408A (en) *	1993-05-10	1996-05-28	Euro Celtique Sa	Controlled release preparation comprising tramadol
DE19530575A1 (de) *	1995-08-19	1997-02-20	Gruenenthal Gmbh	Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
WO1999001111A1 (en) *	1997-07-02	1999-01-14	Euro-Celtique, S.A.	Stabilized sustained release tramadol formulations
DE10015479A1 (de) *	2000-03-29	2001-10-11	Basf Ag	Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität
US6607748B1 (en) *	2000-06-29	2003-08-19	Vincent Lenaerts	Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
DE10108122A1 (de) *	2001-02-21	2002-10-02	Gruenenthal Gmbh	Arzneimittel auf Basis von Tramadol

2003
- 2003-10-27 WO PCT/CA2003/001638 patent/WO2004037222A2/en not_active Ceased
- 2003-10-27 AU AU2003275855A patent/AU2003275855B2/en not_active Expired
- 2003-10-27 PT PT03809237T patent/PT1594460E/pt unknown
- 2003-10-27 JP JP2004545655A patent/JP2006507277A/ja active Pending
- 2003-10-27 AR ARP030103926A patent/AR045972A1/es unknown
- 2003-10-27 KR KR1020057007089A patent/KR20050083816A/ko not_active Ceased
- 2003-10-27 RU RU2005115855/15A patent/RU2328275C2/ru not_active IP Right Cessation
- 2003-10-27 CA CA002503155A patent/CA2503155A1/en not_active Abandoned
- 2003-10-27 UA UAA200504852A patent/UA84277C2/ru unknown
2005
- 2005-04-19 IL IL168114A patent/IL168114A/en active IP Right Grant
- 2005-05-23 NO NO20052479A patent/NO20052479L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL168114A (en)	2011-05-31
RU2005115855A (ru)	2006-01-20
JP2006507277A (ja)	2006-03-02
NO20052479D0 (no)	2005-05-23
CA2503155A1 (en)	2004-05-06
KR20050083816A (ko)	2005-08-26
AR045972A1 (es)	2005-11-23
AU2003275855A1 (en)	2004-05-13
NO20052479L (no)	2005-05-23
PT1594460E (pt)	2008-06-27
RU2328275C2 (ru)	2008-07-10
WO2004037222A3 (en)	2005-09-22
AU2003275855B2 (en)	2009-04-23
WO2004037222A2 (en)	2004-05-06

Publication	Publication Date	Title
WO2004037222A3 (en)	2005-09-22	Sustained-release tramadol formulations with 24-hour efficacy
UA84266C2 (uk)	2008-10-10	Дозована лікарська форма у вигляді таблетки або пелети для перорального введення, яка містить інгібітор pde 4 та полівінілпіролідон, способи її одержання та застосування
GEP20074208B (en)	2007-10-10	Substituted amides active at the cannabinoid-1 receptor
AU2003271024A1 (en)	2004-04-08	Sustained release compound of acetamidophenol and tramadol
NO20080827L (no)	2008-02-15	Faste doseringsformuleringer av narkotiske legemidler som har forbedret bukal adsorpsjon
TWI319713B (en)	2010-01-21	Sustained-release tramadol formulations with 24-hour efficacy
EP2298416A3 (en)	2012-02-15	Sustained-release tramadol formulations with 24-hour clinical efficacy
AU2003225617A1 (en)	2003-09-16	Thiadiazolylpiperazine derivatives useful for treating or preventing pain
EP1708685A4 (en)	2007-12-26	GALENIC FORMS OF EFFERVESCENT ORAL OPIATES AND METHODS OF ADMINISTERING OPIATES
PL370292A1 (en)	2005-05-16	Formulations for oral administration of active compounds
CY1111470T1 (el)	2015-08-05	Νεες φαρμακευτικες συνθεσεις που περιεχουν φλιβανσερινη πολυμορφη α
TW200505823A (en)	2005-02-16	CaSR antagonist
IL158668A0 (en)	2004-05-12	Deuterated 3-piperidinopropiophenone and medicaments containing said compounds
AU2003239389A1 (en)	2003-12-19	Opioid receptor antagonists
NO304113B1 (no)	1998-10-26	Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament
WO2003005967A3 (en)	2003-09-04	Dual release levodopa ethyl ester and decarboxylase in controlled release core
GB2411116A (en)	2005-08-24	Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative
PL350568A1 (en)	2002-12-16	N-(2-phenyl-4-aminobutyl)-1-naphtamides as antagonists of neurokinin 1 receptors
AU2001246999A1 (en)	2001-10-23	New neurokinin antagonists for use as medicaments
MY139228A (en)	2009-08-28	Imidazolinylmethyl aralkylsulfonamides
SI1596841T1 (sl)	2009-06-30	Terapevtski sistem amoksicilina in klavulanske kisline
TW200507838A (en)	2005-03-01	Active substance combination comprising a 2,5-dihydroxybenzenesulfonic compound and a potassium ion channel modulator
NO20050771L (no)	2005-03-31	Bicifadinformulering
AU2001244999A1 (en)	2001-10-23	Naphthamide neurokinin antagonists for use as medicaments
TW200626141A (en)	2006-08-01	Crystalline form of a drug