NO20052560L - Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav. - Google Patents

Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav.

Info

Publication number: NO20052560L
Authority: NO; Norway
Prior art keywords: furo; azabicyclo; carboxamide; oct; preparations
Prior art date: 2002-12-06

Application number

NO20052560A

Other languages

English (en)

Norwegian (no)

Other versions

NO20052560D0 (no

Inventor

Bradley Dee Hewitt

Ahmad Yahya Sheikh

Donn Gregory Wishka

Jon Gordon Selbo

David Warner Rappath

Original Assignee

Pharmacia & Upjohn Co Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-06

Filing date

2005-05-26

Publication date

2005-08-17

2005-05-26 Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc

2005-05-26 Publication of NO20052560D0 publication Critical patent/NO20052560D0/no

2005-08-17 Publication of NO20052560L publication Critical patent/NO20052560L/no

Links

VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical class OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title abstract 3
238000002360 preparation method Methods 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
102000015296 acetylcholine-gated cation-selective channel activity proteins Human genes 0.000 abstract 1
108040006409 acetylcholine-gated cation-selective channel activity proteins Proteins 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
IPKZCLGGYKRDES-UHFFFAOYSA-N n-(1-azabicyclo[2.2.2]octan-3-yl)furo[2,3-c]pyridine-5-carboxamide Chemical class C1N(CC2)CCC2C1NC(=O)C(N=C1)=CC2=C1OC=C2 IPKZCLGGYKRDES-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Addiction (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20052560A 2002-12-06 2005-05-26 Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav. NO20052560L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US43161902P	2002-12-06	2002-12-06
PCT/IB2003/005607 WO2004052894A1 (en)	2002-12-06	2003-12-01	Crystalline fumarate salts of 1-azabicyclo[2.2.2]oct substituted furo[2,3-c]pyridinyl carboxamide and compositions and preparations thereof

Publications (2)

Publication Number	Publication Date
NO20052560D0 NO20052560D0 (no)	2005-05-26
NO20052560L true NO20052560L (no)	2005-08-17

Family

ID=32507764

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20052560A NO20052560L (no)	2002-12-06	2005-05-26	Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav.

Country Status (22)

Country	Link
US (1)	US20050165047A1 (pl)
EP (1)	EP1572700A1 (pl)
JP (1)	JP2006510664A (pl)
KR (1)	KR20050087826A (pl)
CN (1)	CN1720248A (pl)
AR (1)	AR042295A1 (pl)
AU (1)	AU2003302911A1 (pl)
BR (1)	BR0317019A (pl)
CA (1)	CA2506529A1 (pl)
CR (1)	CR7859A (pl)
EA (1)	EA200500738A1 (pl)
EC (1)	ECSP055834A (pl)
HR (1)	HRP20050494A2 (pl)
IS (1)	IS7844A (pl)
MA (1)	MA27604A1 (pl)
MX (1)	MXPA05005943A (pl)
NO (1)	NO20052560L (pl)
OA (1)	OA12968A (pl)
PL (1)	PL377052A1 (pl)
TW (1)	TW200427691A (pl)
WO (1)	WO2004052894A1 (pl)
ZA (1)	ZA200503988B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6670178B1 (en)	1992-07-10	2003-12-30	Transkaryotic Therapies, Inc.	In Vivo production and delivery of insulinotropin for gene therapy
DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
EP1603585A2 (en)	2003-03-14	2005-12-14	Bristol-Myers Squibb Company	Polynucleotide encoding a novel human g-protein coupled receptor variant of hm74, hgprbmy74
US8383657B2 (en)	2007-12-21	2013-02-26	Abbott Laboratories	Thiazolylidine urea and amide derivatives and methods of use thereof
KR20100113163A (ko) *	2008-02-13	2010-10-20	타가셉트 인코포레이티드	알파 ７ 니코틴 작용제 및 항정신병제의 조합
TW201031664A (en)	2009-01-26	2010-09-01	Targacept Inc	Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
PE20170923A1 (es)	2010-05-17	2017-07-12	Forum Pharmaceuticals Inc	Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidratado
EP3461481A1 (en)	2012-05-08	2019-04-03	Forum Pharmaceuticals Inc.	Methods of maintaining, treating or improving cognitive function

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988002751A1 (fr) *	1986-10-13	1988-04-21	Asahi Kasei Kogyo Kabushiki Kaisha	Derives de pyridine
AR036040A1 (es) *	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen

2003
- 2003-12-01 BR BR0317019-5A patent/BR0317019A/pt unknown
- 2003-12-01 MX MXPA05005943A patent/MXPA05005943A/es not_active Application Discontinuation
- 2003-12-01 AU AU2003302911A patent/AU2003302911A1/en not_active Abandoned
- 2003-12-01 CA CA002506529A patent/CA2506529A1/en not_active Abandoned
- 2003-12-01 WO PCT/IB2003/005607 patent/WO2004052894A1/en not_active Ceased
- 2003-12-01 EP EP03812627A patent/EP1572700A1/en not_active Withdrawn
- 2003-12-01 PL PL377052A patent/PL377052A1/pl not_active Application Discontinuation
- 2003-12-01 KR KR1020057010196A patent/KR20050087826A/ko not_active Ceased
- 2003-12-01 CN CNA200380105166XA patent/CN1720248A/zh active Pending
- 2003-12-01 EA EA200500738A patent/EA200500738A1/ru unknown
- 2003-12-01 HR HR20050494A patent/HRP20050494A2/hr not_active Application Discontinuation
- 2003-12-01 JP JP2004558940A patent/JP2006510664A/ja active Pending
- 2003-12-01 OA OA1200500173A patent/OA12968A/en unknown
- 2003-12-04 AR ARP030104471A patent/AR042295A1/es unknown
- 2003-12-05 TW TW092134360A patent/TW200427691A/zh unknown
2004
- 2004-10-08 US US10/962,071 patent/US20050165047A1/en not_active Abandoned
2005
- 2005-05-12 IS IS7844A patent/IS7844A/is unknown
- 2005-05-17 ZA ZA200503988A patent/ZA200503988B/en unknown
- 2005-05-26 NO NO20052560A patent/NO20052560L/no not_active Application Discontinuation
- 2005-06-03 EC EC2005005834A patent/ECSP055834A/es unknown
- 2005-06-06 CR CR7859A patent/CR7859A/es not_active Application Discontinuation
- 2005-06-06 MA MA28315A patent/MA27604A1/fr unknown

Also Published As

Publication number	Publication date
PL377052A1 (pl)	2006-01-23
MXPA05005943A (es)	2005-08-18
IS7844A (is)	2005-05-12
MA27604A1 (fr)	2005-11-01
TW200427691A (en)	2004-12-16
NO20052560D0 (no)	2005-05-26
EP1572700A1 (en)	2005-09-14
ECSP055834A (es)	2005-08-11
KR20050087826A (ko)	2005-08-31
OA12968A (en)	2006-10-13
CR7859A (es)	2005-07-08
US20050165047A1 (en)	2005-07-28
ZA200503988B (en)	2006-09-27
EA200500738A1 (ru)	2005-12-29
AR042295A1 (es)	2005-06-15
JP2006510664A (ja)	2006-03-30
BR0317019A (pt)	2005-10-25
CN1720248A (zh)	2006-01-11
WO2004052894A1 (en)	2004-06-24
CA2506529A1 (en)	2004-06-24
AU2003302911A1 (en)	2004-06-30
HRP20050494A2 (en)	2005-10-31

Legal Events

Date	Code	Title	Description
2007-08-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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NO308772B1 (no)	2000-10-30	Sublingual eller buckal farmasoytisk blanding inneholdende trans-5-klor-2-metyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oksepino[4,5-c]pyrrol, samt anvendelse av forbindelsen for fremstilling av farmasoytisk blanding
WO2003093250A3 (en)	2004-12-23	Positive allosteric modulators of the nicotinic acetylcholine receptor
DE69427704D1 (de)	2001-08-16	Neue (r)-5-carbamoyl-8-fluor-3-n,n-disubstituierte-amino-3,4-dihydro-2h-1-benzopyrane
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NO20052560L (no)	2005-08-17	Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav.
RU94046220A (ru)	1996-09-27	N/гетеро/-арил-n/гетеро/-тетралин-алкилпиперазин, обладающий серотонинергической, допаминергической и адренергической активностью, способ их получения, терапевтическая композиция, применение
IL78661A (en)	1992-08-18	Bone targeted inhibitors of carbonic anhydrase and methods for the preparation thereof
GB9109972D0 (en)	1991-07-03	Therapeutic compounds
NO903384L (no)	1991-02-04	Fremgangsmaate for fremstilling av 4-(n-substituert amino)-2-butynyl-1-urinstoffer og -tiourinstoffer og derivater derav.
HUT52377A (en)	1990-07-28	Process for producing pharmaceutical compositions comprising 3-substituted-2-oxindole-1-carboxamide derivatives as active ingredient
PL376368A1 (pl)	2005-12-27	Pochodne 4-aminopiperydyny, sposoby ich wytwarzania i ich zastosowanie jako leków
AU567018B2 (en)	1987-11-05	Prazosin-pirbuterol combination for bronchoduation
ZA891769B (en)	1989-12-27	Heterocyclic compounds
YU24603A (sh)	2006-05-25	Novi farmaceutski preparati koji sadrže epinastin i pseudoefedrin
GR850995B (pl)	1985-11-25