PL377052A1 - Krystaliczne fumarany 1-azabicyklo [2,2,2] oktylofuro [2,3-c] pirydynylokarboksyamidu oraz ich kompozycje i preparaty - Google Patents

Krystaliczne fumarany 1-azabicyklo [2,2,2] oktylofuro [2,3-c] pirydynylokarboksyamidu oraz ich kompozycje i preparaty

Info

Publication number: PL377052A1
Authority: PL; Poland
Prior art keywords: azabicyclo; oct; preparations; compositions; fumarate salts
Prior art date: 2002-12-06

Application number

PL377052A

Other languages

English (en)

Inventor

Jon Gordon Selbo

Bradley Dee Hewitt

David Warner Rappath

Donn Gregory Wishka

Ahmad Yahya Sheikh

Original Assignee

Pharmacia & Upjohn Company Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-06

Filing date

2003-12-01

Publication date

2006-01-23

2003-12-01 Application filed by Pharmacia & Upjohn Company Llc filed Critical Pharmacia & Upjohn Company Llc

2006-01-23 Publication of PL377052A1 publication Critical patent/PL377052A1/pl

Links

VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical class OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title 1
ZFCRPEXKMXOUQT-UHFFFAOYSA-N furo[2,3-c]pyridine-2-carboxamide Chemical class C1=NC=C2OC(C(=O)N)=CC2=C1 ZFCRPEXKMXOUQT-UHFFFAOYSA-N 0.000 title 1
239000000203 mixture Chemical class 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Addiction (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL377052A 2002-12-06 2003-12-01 Krystaliczne fumarany 1-azabicyklo [2,2,2] oktylofuro [2,3-c] pirydynylokarboksyamidu oraz ich kompozycje i preparaty PL377052A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US43161902P	2002-12-06	2002-12-06

Publications (1)

Publication Number	Publication Date
PL377052A1 true PL377052A1 (pl)	2006-01-23

Family

ID=32507764

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL377052A PL377052A1 (pl)	2002-12-06	2003-12-01	Krystaliczne fumarany 1-azabicyklo [2,2,2] oktylofuro [2,3-c] pirydynylokarboksyamidu oraz ich kompozycje i preparaty

Country Status (22)

Country	Link
US (1)	US20050165047A1 (pl)
EP (1)	EP1572700A1 (pl)
JP (1)	JP2006510664A (pl)
KR (1)	KR20050087826A (pl)
CN (1)	CN1720248A (pl)
AR (1)	AR042295A1 (pl)
AU (1)	AU2003302911A1 (pl)
BR (1)	BR0317019A (pl)
CA (1)	CA2506529A1 (pl)
CR (1)	CR7859A (pl)
EA (1)	EA200500738A1 (pl)
EC (1)	ECSP055834A (pl)
HR (1)	HRP20050494A2 (pl)
IS (1)	IS7844A (pl)
MA (1)	MA27604A1 (pl)
MX (1)	MXPA05005943A (pl)
NO (1)	NO20052560L (pl)
OA (1)	OA12968A (pl)
PL (1)	PL377052A1 (pl)
TW (1)	TW200427691A (pl)
WO (1)	WO2004052894A1 (pl)
ZA (1)	ZA200503988B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6670178B1 (en)	1992-07-10	2003-12-30	Transkaryotic Therapies, Inc.	In Vivo production and delivery of insulinotropin for gene therapy
DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
EP1603585A2 (en)	2003-03-14	2005-12-14	Bristol-Myers Squibb Company	Polynucleotide encoding a novel human g-protein coupled receptor variant of hm74, hgprbmy74
US8383657B2 (en)	2007-12-21	2013-02-26	Abbott Laboratories	Thiazolylidine urea and amide derivatives and methods of use thereof
KR20100113163A (ko) *	2008-02-13	2010-10-20	타가셉트 인코포레이티드	알파 ７ 니코틴 작용제 및 항정신병제의 조합
TW201031664A (en)	2009-01-26	2010-09-01	Targacept Inc	Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
PE20170923A1 (es)	2010-05-17	2017-07-12	Forum Pharmaceuticals Inc	Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidratado
EP3461481A1 (en)	2012-05-08	2019-04-03	Forum Pharmaceuticals Inc.	Methods of maintaining, treating or improving cognitive function

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988002751A1 (fr) *	1986-10-13	1988-04-21	Asahi Kasei Kogyo Kabushiki Kaisha	Derives de pyridine
AR036040A1 (es) *	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen

2003
- 2003-12-01 BR BR0317019-5A patent/BR0317019A/pt unknown
- 2003-12-01 MX MXPA05005943A patent/MXPA05005943A/es not_active Application Discontinuation
- 2003-12-01 AU AU2003302911A patent/AU2003302911A1/en not_active Abandoned
- 2003-12-01 CA CA002506529A patent/CA2506529A1/en not_active Abandoned
- 2003-12-01 WO PCT/IB2003/005607 patent/WO2004052894A1/en not_active Ceased
- 2003-12-01 EP EP03812627A patent/EP1572700A1/en not_active Withdrawn
- 2003-12-01 PL PL377052A patent/PL377052A1/pl not_active Application Discontinuation
- 2003-12-01 KR KR1020057010196A patent/KR20050087826A/ko not_active Ceased
- 2003-12-01 CN CNA200380105166XA patent/CN1720248A/zh active Pending
- 2003-12-01 EA EA200500738A patent/EA200500738A1/ru unknown
- 2003-12-01 HR HR20050494A patent/HRP20050494A2/hr not_active Application Discontinuation
- 2003-12-01 JP JP2004558940A patent/JP2006510664A/ja active Pending
- 2003-12-01 OA OA1200500173A patent/OA12968A/en unknown
- 2003-12-04 AR ARP030104471A patent/AR042295A1/es unknown
- 2003-12-05 TW TW092134360A patent/TW200427691A/zh unknown
2004
- 2004-10-08 US US10/962,071 patent/US20050165047A1/en not_active Abandoned
2005
- 2005-05-12 IS IS7844A patent/IS7844A/is unknown
- 2005-05-17 ZA ZA200503988A patent/ZA200503988B/en unknown
- 2005-05-26 NO NO20052560A patent/NO20052560L/no not_active Application Discontinuation
- 2005-06-03 EC EC2005005834A patent/ECSP055834A/es unknown
- 2005-06-06 CR CR7859A patent/CR7859A/es not_active Application Discontinuation
- 2005-06-06 MA MA28315A patent/MA27604A1/fr unknown

Also Published As

Publication number	Publication date
MXPA05005943A (es)	2005-08-18
IS7844A (is)	2005-05-12
MA27604A1 (fr)	2005-11-01
TW200427691A (en)	2004-12-16
NO20052560D0 (no)	2005-05-26
EP1572700A1 (en)	2005-09-14
ECSP055834A (es)	2005-08-11
KR20050087826A (ko)	2005-08-31
OA12968A (en)	2006-10-13
CR7859A (es)	2005-07-08
US20050165047A1 (en)	2005-07-28
ZA200503988B (en)	2006-09-27
EA200500738A1 (ru)	2005-12-29
AR042295A1 (es)	2005-06-15
NO20052560L (no)	2005-08-17
JP2006510664A (ja)	2006-03-30
BR0317019A (pt)	2005-10-25
CN1720248A (zh)	2006-01-11
WO2004052894A1 (en)	2004-06-24
CA2506529A1 (en)	2004-06-24
AU2003302911A1 (en)	2004-06-30
HRP20050494A2 (en)	2005-10-31

Legal Events

Date	Code	Title	Description
2011-09-30	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
HUP1100350A2 (en)	2003-09-29	Maleate addition salts of hydropyridine derivates
AU2003233010A8 (en)	2003-12-19	Process for the preparation of 3,3,4,4-tetrafluoropyrrolidine and derivatives thereof
AU2002321878A1 (en)	2003-02-17	Pyridinone and pyridazinone derivatives as gonadotropin-releasing hormone receptor antagonists
IL172994A0 (en)	2006-06-11	Substituted tetrahydro-1h-pyrazolo[3,4-c]pyridines, compositions containing them, and use
WO2000055125A3 (en)	2001-04-26	N-cyanomethyl amides as protease inhibitors
PL392790A1 (pl)	2011-01-03	Związki pirazolo [3, 4-b] pirydynowe i ich zastosowanie jako inhibitorów fosfodiesterazy
IL191960A (en)	2015-11-30	History of imidazo [5,1– a] pyridine and pharmaceutical preparations containing them
AU2003229772A1 (en)	2003-12-02	Derivatives of 2-(1-benzyl-1h-pyrazolo (3, 4-b)pyridine-3yl) -5-(4-pyridinyl)-4-pyrimidine amine and the use thereof as guanylate cyclase stimulators
IL154306A0 (en)	2003-09-17	Pharmaceutical compositions comprising thieno [2,3-c] pyridine derivatives and use thereof
AU2002225894A1 (en)	2002-05-21	Methods and compositions for the control of coccidiosis
IL163287A (en)	2009-12-24	HETEROARYL SUBSTITUTED 2 - PYRIDINYL AND 2 - PYRIMIDINYL - 6,7,8,9 - TETRAHYDROPYRIMIDO [1,2-a] PYRIMIDIN - 4 - ONE DERIVATIVES
IL152582A0 (en)	2003-05-29	5-chloro-3-(4-methanesulfonylphenyl)-6'-methyl-[2,3']bipyridinyl in pure crystalline form and process for synthesis
PL377052A1 (pl)	2006-01-23	Krystaliczne fumarany 1-azabicyklo [2,2,2] oktylofuro [2,3-c] pirydynylokarboksyamidu oraz ich kompozycje i preparaty
IL164887A0 (en)	2005-12-18	Therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions and methods therewith
AU2003260984A1 (en)	2004-04-30	S-(-)-amlodipine nicotinate and process for the preparation thereof
PL401254A1 (pl)	2013-01-07	Mieszanina chwastobójcza, sposób zwalczania niepozadanej roslinnosci i zastosowanie mieszaniny chwastobójczej
AU1054500A (en)	2000-05-22	N-substituted (3,6-dihydro)-2h-1,2-oxazine derivatives, their preparation and their use as selective mglur1 antagonists
IL162524A0 (en)	2005-11-20	Derivatives of (pyridin-3-yl)-1-azabicycloÄ3.2.1Ü octane, their preparation and their terapeutic application
MXPA02007039A (es)	2003-09-25	Crecimiento ocular y antagonistas nicotinicos.
AU2002366092A1 (en)	2003-06-10	1h-pyrrolo(3,2-b)pyridine-3-carboxylic acid amides
AU2002368487A1 (en)	2004-07-14	Substituted 1,4-di-piperidin-4-yl-piperazine derivatives and their use as tachykinin antagonists
HUP0204111A3 (en)	2005-05-30	Novel process for the preparation of alpha-(2,4-disulfophenyl)-n-tert-butylnitrone and pharmaceutically acceptable salts thereof
AU2002364696A8 (en)	2003-06-23	Crystalline neutrokine-alpha protein, method of preparation thereof, and method of use thereof
IL147128A0 (en)	2002-08-14	DITHIEPINO [6,5-b]PYRIDINES, AND RELATED COMPOSITIONS AND METHODS
AU2003256491A1 (en)	2004-02-02	Furopyridine and furopyrimidine derivatives for the treatment of hyper-proliferative disorders