NO20053548L - Pulvermedikament for inhalering inneholdende et tiotropiumsalt og salmeterolxinafoat. - Google Patents
Pulvermedikament for inhalering inneholdende et tiotropiumsalt og salmeterolxinafoat.Info
- Publication number
- NO20053548L NO20053548L NO20053548A NO20053548A NO20053548L NO 20053548 L NO20053548 L NO 20053548L NO 20053548 A NO20053548 A NO 20053548A NO 20053548 A NO20053548 A NO 20053548A NO 20053548 L NO20053548 L NO 20053548L
- Authority
- NO
- Norway
- Prior art keywords
- powder
- salmeterol xinafoate
- tiotropium salt
- inhalation containing
- inhalation
- Prior art date
Links
- GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 title abstract 2
- 229960005018 salmeterol xinafoate Drugs 0.000 title abstract 2
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical class O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title abstract 2
- 239000000843 powder Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 3
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 2
- 208000006673 asthma Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Det beskrives pulverformede tilberedninger for inhalasjon, inneholdende et tiotropiumsalt og salmeterolxinafoat, fremgangsmåter for fremstilling av disse, samt deres anvendelse til fremstilling av et legemiddel til behandling av luftveissykdommer, særlig til behandling av COPD (chronic obstructive pulmonary disease) og astma.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10259912 | 2002-12-20 | ||
| PCT/EP2003/013691 WO2004058233A1 (de) | 2002-12-20 | 2003-12-04 | Pulverförmige arzneimittel zur inhalation enthaltend ein tiotropiumsalz und salmeterolxinafoat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20053548L true NO20053548L (no) | 2005-09-02 |
Family
ID=32404034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053548A NO20053548L (no) | 2002-12-20 | 2005-07-19 | Pulvermedikament for inhalering inneholdende et tiotropiumsalt og salmeterolxinafoat. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1581198A1 (no) |
| JP (1) | JP2006516135A (no) |
| KR (1) | KR20050086930A (no) |
| CN (1) | CN1728988B (no) |
| AU (1) | AU2003288226B2 (no) |
| BR (1) | BR0317443A (no) |
| CA (1) | CA2510779A1 (no) |
| DE (1) | DE10351663A1 (no) |
| EA (1) | EA010588B1 (no) |
| EC (1) | ECSP055855A (no) |
| FR (1) | FR2848849B1 (no) |
| HR (1) | HRP20050570A2 (no) |
| IT (1) | ITMI20032473A1 (no) |
| MX (1) | MXPA05006519A (no) |
| NO (1) | NO20053548L (no) |
| NZ (1) | NZ541303A (no) |
| PL (1) | PL376231A1 (no) |
| RS (1) | RS20050484A (no) |
| UA (1) | UA83813C2 (no) |
| WO (1) | WO2004058233A1 (no) |
| ZA (1) | ZA200503692B (no) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| JP4342426B2 (ja) * | 2004-11-24 | 2009-10-14 | 科研製薬株式会社 | イトラコナゾール経口投与用製剤 |
| WO2007017437A1 (en) * | 2005-08-06 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Method for the treatment of dyspnea comprising combined administration of tiotropium salts and salts of salmeterol |
| US8163913B2 (en) | 2005-12-19 | 2012-04-24 | Sicor Inc. | Forms of tiotropium bromide and processes for preparation thereof |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| EP2540725A1 (de) | 2006-05-04 | 2013-01-02 | Boehringer Ingelheim International GmbH | Polymorphe von 1-((4-Methyl-chinazolin-2-yl)methyl)-3-methyl-7-(2-butin-1-yl)-8-(3-(R)-amino-piperidin-1-yl)xanthin |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| DE102007036411A1 (de) * | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| PE20090907A1 (es) * | 2007-07-21 | 2009-08-05 | Boehringer Ingelheim Int | Nuevos medicamentos pulverulentos que contienen tiotropio y salmeterol, asi como lactosa como excipiente |
| PE20091730A1 (es) | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| CN102256976A (zh) | 2008-12-23 | 2011-11-23 | 贝林格尔.英格海姆国际有限公司 | 有机化合物的盐形式 |
| AR074990A1 (es) | 2009-01-07 | 2011-03-02 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina |
| KR20240090632A (ko) | 2009-11-27 | 2024-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
| CN102946875A (zh) | 2010-05-05 | 2013-02-27 | 贝林格尔.英格海姆国际有限公司 | 组合疗法 |
| WO2011161161A1 (en) | 2010-06-24 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Diabetes therapy |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| US8883800B2 (en) | 2011-07-15 | 2014-11-11 | Boehringer Ingelheim International Gmbh | Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| JP6218811B2 (ja) | 2012-05-14 | 2017-10-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Sirs及び/又は敗血症の治療に用いるdpp−4阻害薬としてのキサンチン誘導体 |
| JP6224084B2 (ja) | 2012-05-14 | 2017-11-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糸球体上皮細胞関連障害及び/又はネフローゼ症候群の治療に用いるdpp−4阻害薬としてのキサンチン誘導体 |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| EP3110449B1 (en) | 2014-02-28 | 2023-06-28 | Boehringer Ingelheim International GmbH | Medical use of a dpp-4 inhibitor |
| KR101748796B1 (ko) * | 2015-09-30 | 2017-06-19 | 한미약품 주식회사 | 활성성분의 전달량이 향상된 흡입용 캡슐제 |
| CN109310697A (zh) | 2016-06-10 | 2019-02-05 | 勃林格殷格翰国际有限公司 | 利格列汀和二甲双胍的组合 |
| BR112021009254A2 (pt) * | 2018-11-13 | 2021-08-10 | Cocrystal Pharma, Inc. | formulações para produtos terapêuticos para influenza |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993016031A1 (en) * | 1992-02-11 | 1993-08-19 | Glaxo Group Limited | Benzenedimethanol derivative suitable for micronisation |
| CN1056974C (zh) * | 1992-02-11 | 2000-10-04 | 格拉克索公司 | 适宜于微粒化的药物材料的制备方法 |
| GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
| DE10056104A1 (de) * | 2000-11-13 | 2002-05-23 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Tiotropiumsalzen und Salzen des Salmeterols |
| DE10104367A1 (de) * | 2001-02-01 | 2002-08-08 | Boehringer Ingelheim Pharma | Betamimetika enthaltende Arzneimittelkompositionen mit geringeren Nebenwirkungen |
| DE10130371A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
| EP1416990A1 (en) * | 2001-08-09 | 2004-05-12 | Glaxo Group Limited | Inhalation device with a pharmaceutical composition |
| JP2005504076A (ja) * | 2001-09-14 | 2005-02-10 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 新規な吸入用医薬組成物 |
-
2003
- 2003-04-12 UA UAA200507088A patent/UA83813C2/ru unknown
- 2003-11-05 DE DE10351663A patent/DE10351663A1/de not_active Withdrawn
- 2003-12-04 RS YUP-2005/0484A patent/RS20050484A/sr unknown
- 2003-12-04 CN CN2003801069216A patent/CN1728988B/zh not_active Expired - Fee Related
- 2003-12-04 KR KR1020057011668A patent/KR20050086930A/ko not_active Ceased
- 2003-12-04 BR BR0317443-3A patent/BR0317443A/pt not_active IP Right Cessation
- 2003-12-04 HR HR20050570A patent/HRP20050570A2/xx not_active Application Discontinuation
- 2003-12-04 WO PCT/EP2003/013691 patent/WO2004058233A1/de not_active Ceased
- 2003-12-04 JP JP2004562686A patent/JP2006516135A/ja active Pending
- 2003-12-04 PL PL03376231A patent/PL376231A1/xx not_active Application Discontinuation
- 2003-12-04 EA EA200500902A patent/EA010588B1/ru not_active IP Right Cessation
- 2003-12-04 NZ NZ541303A patent/NZ541303A/en unknown
- 2003-12-04 EP EP03780120A patent/EP1581198A1/de not_active Withdrawn
- 2003-12-04 CA CA002510779A patent/CA2510779A1/en not_active Abandoned
- 2003-12-04 AU AU2003288226A patent/AU2003288226B2/en not_active Ceased
- 2003-12-04 MX MXPA05006519A patent/MXPA05006519A/es unknown
- 2003-12-16 IT IT002473A patent/ITMI20032473A1/it unknown
- 2003-12-19 FR FR0315082A patent/FR2848849B1/fr not_active Expired - Fee Related
-
2005
- 2005-05-09 ZA ZA200503692A patent/ZA200503692B/en unknown
- 2005-06-15 EC EC2005005855A patent/ECSP055855A/es unknown
- 2005-07-19 NO NO20053548A patent/NO20053548L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003288226A1 (en) | 2004-07-22 |
| AU2003288226B2 (en) | 2010-01-07 |
| KR20050086930A (ko) | 2005-08-30 |
| CN1728988A (zh) | 2006-02-01 |
| ECSP055855A (es) | 2005-11-22 |
| PL376231A1 (en) | 2005-12-27 |
| CA2510779A1 (en) | 2004-07-15 |
| BR0317443A (pt) | 2005-11-16 |
| ITMI20032473A1 (it) | 2004-06-21 |
| UA83813C2 (ru) | 2008-08-26 |
| HRP20050570A2 (en) | 2006-07-31 |
| MXPA05006519A (es) | 2005-08-26 |
| EP1581198A1 (de) | 2005-10-05 |
| EA010588B1 (ru) | 2008-10-30 |
| NZ541303A (en) | 2008-11-28 |
| WO2004058233A1 (de) | 2004-07-15 |
| JP2006516135A (ja) | 2006-06-22 |
| CN1728988B (zh) | 2010-04-28 |
| DE10351663A1 (de) | 2004-07-01 |
| EA200500902A1 (ru) | 2006-02-24 |
| ZA200503692B (en) | 2006-10-25 |
| FR2848849A1 (fr) | 2004-06-25 |
| RS20050484A (sr) | 2007-11-15 |
| FR2848849B1 (fr) | 2007-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |