NO20061441L - Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse - Google Patents

Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse

Info

Publication number
NO20061441L
NO20061441L NO20061441A NO20061441A NO20061441L NO 20061441 L NO20061441 L NO 20061441L NO 20061441 A NO20061441 A NO 20061441A NO 20061441 A NO20061441 A NO 20061441A NO 20061441 L NO20061441 L NO 20061441L
Authority
NO
Norway
Prior art keywords
preparation
methods
formulations containing
pharmaceutical formulations
tiotropium salts
Prior art date
Application number
NO20061441A
Other languages
English (en)
Inventor
Rolf Banholzer
Waldemar Pfrengle
Peter Sieger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34530661&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20061441(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO20061441L publication Critical patent/NO20061441L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Oppfinnelsen angår nye tiotropiumsalter, metoder for fremstilling av disse, legemiddelformuleringer som inneholder disse, og anvendelsen derav for fremstilling av et legemiddel som blir anvendt for behandling av luftveislidelser, spesielt KOLS (kronisk obstmktiv lungesykdom) og astma.
NO20061441A 2003-11-03 2006-03-30 Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse NO20061441L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025076 2003-11-03
PCT/EP2004/012270 WO2005042528A1 (de) 2003-11-03 2004-10-29 Neue tiotropiumsalze, verfahren zu deren herstellung sowie diese enthaltende arzneimittelformulierungen

Publications (1)

Publication Number Publication Date
NO20061441L true NO20061441L (no) 2006-07-12

Family

ID=34530661

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061441A NO20061441L (no) 2003-11-03 2006-03-30 Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse

Country Status (28)

Country Link
US (1) US20050096341A1 (no)
EP (5) EP2083007B1 (no)
JP (1) JP5165245B2 (no)
KR (1) KR20060102561A (no)
CN (3) CN102964344B (no)
AR (1) AR046318A1 (no)
AT (1) ATE478071T1 (no)
AU (1) AU2004285685B2 (no)
CA (1) CA2544357A1 (no)
CO (1) CO5690554A2 (no)
DE (1) DE502004011562D1 (no)
DK (2) DK2083007T3 (no)
EA (1) EA012369B1 (no)
EC (2) ECSP066545A (no)
ES (2) ES2422730T3 (no)
IL (1) IL175127A (no)
MY (1) MY145166A (no)
NO (1) NO20061441L (no)
NZ (1) NZ547523A (no)
PE (1) PE20050485A1 (no)
PL (1) PL2083007T3 (no)
RS (1) RS20060293A (no)
SG (1) SG149876A1 (no)
TW (1) TW200523263A (no)
UA (1) UA82414C2 (no)
UY (1) UY28589A1 (no)
WO (1) WO2005042528A1 (no)
ZA (1) ZA200602343B (no)

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JP5165244B2 (ja) 2003-11-03 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング チオトロピウム塩の製法、チオトロピウム塩及びそれを含有する医薬組成物
NZ564697A (en) * 2005-06-15 2010-04-30 Boehringer Ingelheim Int Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
JP2008543806A (ja) * 2005-06-17 2008-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療のためのｍｒｐｉｖインヒビター
DE102005035112A1 (de) * 2005-07-27 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Verfahren zur Herstellung von Tiotropiumsalzen unter Anwendung von in organischen Lösungsmitteln löslichen N-Methylscopiniumsalzen
US20070167480A1 (en) * 2005-12-19 2007-07-19 Sicor Inc. Pure and stable tiotropium bromide
US9108962B2 (en) 2005-12-19 2015-08-18 Sicor, Inc. Forms of tiotropium bromide and processes for preparation thereof
US8163913B2 (en) * 2005-12-19 2012-04-24 Sicor Inc. Forms of tiotropium bromide and processes for preparation thereof
MX2007009987A (es) * 2005-12-19 2007-10-02 Sicor Inc Bromuro de tiotropio puro y estable.
US20080051582A1 (en) * 2006-07-10 2008-02-28 Sicor Inc. Process for the preparation of tiotropium bromide
EP1925295A1 (de) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
WO2008089852A1 (de) * 2007-01-26 2008-07-31 Boehringer Ingelheim Pharma Gmbh & Co.Kg Neues verfahren zur herstellung von tiotropiumsalzen
EP1953156A1 (de) * 2007-01-29 2008-08-06 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Scopiniumsalzen
WO2010110760A1 (en) * 2009-03-27 2010-09-30 Mahmut Bilgic Compositions comprising water with deuterium for the prevention or treatment of allergic diseases and a process for the preparation thereof
PL388070A1 (pl) * 2009-05-19 2010-11-22 Adamed Spółka Z Ograniczoną Odpowiedzialnością Nowe sole tiotropium
CZ201241A3 (cs) * 2012-01-20 2013-07-31 Zentiva, K.S. Nové polymorfní formy tiotropium jodidu a zpusob jejich prípravy
EP2819669B1 (de) * 2012-02-28 2021-04-21 Boehringer Ingelheim International GmbH Neue treibgashaltige tiotropium-formulierung

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US3551492A (en) * 1967-10-31 1970-12-29 Ciba Geigy Corp N,n'-diaminoalkoxy-benzyl-diamino-alkanes and the salts thereof
US4570630A (en) 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
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Also Published As

Publication number Publication date
EP2083007A1 (de) 2009-07-29
ZA200602343B (en) 2007-12-27
JP2007509895A (ja) 2007-04-19
TW200523263A (en) 2005-07-16
ES2422730T3 (es) 2013-09-13
CN102964344A (zh) 2013-03-13
KR20060102561A (ko) 2006-09-27
EA200600854A1 (ru) 2006-10-27
ATE478071T1 (de) 2010-09-15
MY145166A (en) 2011-12-30
ES2350981T3 (es) 2011-01-28
IL175127A (en) 2011-10-31
EP2322522A1 (de) 2011-05-18
CN101648950B (zh) 2014-05-07
AU2004285685A1 (en) 2005-05-12
PL2083007T3 (pl) 2013-09-30
CN1875020A (zh) 2006-12-06
DK2083007T3 (da) 2013-07-29
CN1875020B (zh) 2010-04-28
AR046318A1 (es) 2005-11-30
EP2083007B1 (de) 2013-04-24
CN101648950A (zh) 2010-02-17
NZ547523A (en) 2009-07-31
SG149876A1 (en) 2009-02-27
RS20060293A (sr) 2008-08-07
EP1682543B1 (de) 2010-08-18
DE502004011562D1 (de) 2010-09-30
CO5690554A2 (es) 2006-10-31
UA82414C2 (uk) 2008-04-10
US20050096341A1 (en) 2005-05-05
PE20050485A1 (es) 2005-10-05
AU2004285685B2 (en) 2011-03-24
EA012369B1 (ru) 2009-10-30
DK1682543T3 (da) 2010-12-13
IL175127A0 (en) 2006-09-05
EP2319844A1 (de) 2011-05-11
JP5165245B2 (ja) 2013-03-21
EP1682543A1 (de) 2006-07-26
HK1099753A1 (zh) 2007-08-24
ECSP066544A (es) 2006-10-17
CN102964344B (zh) 2014-12-31
CA2544357A1 (en) 2005-05-12
ECSP066545A (es) 2006-10-17
WO2005042528A1 (de) 2005-05-12
EP2336127A1 (de) 2011-06-22
UY28589A1 (es) 2005-06-30

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