NO20053613L - Fremgangsmate for fremstilling av rasemiske citalopramdioler og/eller S-eller R-citalopramdioler samt anvendelse av slike dioler ved fremstilling av rasemisk citalopram, R-citalopram og/eller S-citalopram - Google Patents

Fremgangsmate for fremstilling av rasemiske citalopramdioler og/eller S-eller R-citalopramdioler samt anvendelse av slike dioler ved fremstilling av rasemisk citalopram, R-citalopram og/eller S-citalopram

Info

Publication number: NO20053613L
Authority: NO; Norway
Prior art keywords: citalopram; diols; preparation; racemic; racemic citalopram
Prior art date: 2002-12-23

Application number

NO20053613A

Other languages

English (en)

Other versions

NO331181B1 (no

NO20053613D0 (no

Inventor

Hans Petersen

Rikke Eva Humble

Robert Dancer

Brian Christiansen

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-23

Filing date

2005-07-25

Publication date

2005-09-15

2005-07-25 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2005-07-25 Publication of NO20053613D0 publication Critical patent/NO20053613D0/no

2005-09-15 Publication of NO20053613L publication Critical patent/NO20053613L/no

2011-10-24 Publication of NO331181B1 publication Critical patent/NO331181B1/no

Links

229960001653 citalopram Drugs 0.000 title 3
WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 title 2
-1 citalopram diols Chemical class 0.000 title 2
150000002009 diols Chemical class 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20053613A 2002-12-23 2005-07-25 Fremgangsmate for fremstilling av racemisk citalopramdiol og/eller S- eller R-citalopramdioler NO331181B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US43611702P	2002-12-23	2002-12-23
DKPA200202004		2002-12-23
PCT/DK2003/000907 WO2004056754A1 (en)	2002-12-23	2003-12-18	A process for the preparation of racemic citalopram diol and/or s- or r- citalopram diols and the use of such diols for the preparation of racemic citalopram, r-citalopram and/or s-citalopram

Publications (3)

Publication Number	Publication Date
NO20053613D0 NO20053613D0 (no)	2005-07-25
NO20053613L true NO20053613L (no)	2005-09-15
NO331181B1 NO331181B1 (no)	2011-10-24

Family

ID=32683721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20053613A NO331181B1 (no)	2002-12-23	2005-07-25	Fremgangsmate for fremstilling av racemisk citalopramdiol og/eller S- eller R-citalopramdioler

Country Status (13)

Country	Link
US (1)	US7390913B2 (no)
EP (2)	EP2363389A1 (no)
JP (1)	JP4505335B2 (no)
AU (1)	AU2003291960B2 (no)
CA (1)	CA2511143C (no)
CY (1)	CY1112937T1 (no)
IL (1)	IL169330A0 (no)
IS (1)	IS2862B (no)
MX (1)	MXPA05006783A (no)
NO (1)	NO331181B1 (no)
NZ (1)	NZ540653A (no)
PL (1)	PL207847B1 (no)
WO (1)	WO2004056754A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN100569765C (zh) *	2003-12-19	2009-12-16	杭州民生药业集团有限公司	西酞普兰中间体晶体碱
TWI339651B (en) *	2004-02-12	2011-04-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
ITMI20041872A1 (it)	2004-10-01	2005-01-01	Adorkem Technology Spa	Processo per la preparazione di citalopram e di scitalopram
GB0425320D0 (en)	2004-11-17	2004-12-22	Johnson Matthey Plc	Diamines
WO2007012954A1 (en) *	2005-07-27	2007-02-01	Aurobindo Pharma Limited	An improved process for the preparation of escitalopram
NZ570884A (en)	2007-09-11	2010-03-26	Lundbeck & Co As H	Fractionally crystallising 4-[4-(dimethyl amino)-1-(4'-fluorophenyl)-1-hydroxybutyI]-3-(hydroxymethyl)-benzonitrile and manufacturing escitalopram therefrom
US8022232B2 (en)	2007-09-11	2011-09-20	H. Lundbeck A/S	Method for manufacture of escitalopram
CA2833809A1 (en)	2011-04-29	2012-11-01	Saint-Gobain Performance Plastics Corporation	Maintenance-free slide bearing with fep or pfa in the adhesive layer
FR2985215B1 (fr)	2011-12-28	2014-09-19	Saint Gobain Performance Plast	Revetements polymeres deposes sur des substrats par des techniques de projection thermique
CN103182808A (zh)	2011-12-28	2013-07-03	圣戈班高功能塑料集团	一种包括含氟聚合物表面层以及非氟聚合物过渡层的多层复合物
CN104364079B (zh)	2012-06-29	2017-12-12	圣戈班性能塑料帕姆普斯有限公司	包含底漆体系作为粘附促进剂的滑动轴承
WO2014049137A1 (en)	2012-09-28	2014-04-03	Saint-Gobain Performance Plastics Pampus Gmbh	Maintenance-free slide bearing with a combined adhesive sliding layer
DK201500520A1 (en) *	2015-08-31	2016-09-19	H Lundbeck As	Crystalline forms of (R)-4-[4-(dimethylamino)-1-(4'-fluorophenyl)-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile free base and (S)-4-[4-(dimethylamino)-1-(4'-fluoro-phenyl)-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile free base and of racemic 4-[4-(dimethylamino)-1-(4'-fluorophenyl)-hydroxybutyl]-3-(hydroxyl-methyl)-benzonitrile toluene hemisolvate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
JP2001123239A (ja)	1999-10-21	2001-05-08	Daiki Aluminium Industry Co Ltd	高強度鋳造用アルミニウム合金及び同アルミニウム合金鋳物
AR034612A1 (es)	2001-06-25	2004-03-03	Lundbeck & Co As H	Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es)	2001-07-13	2004-03-17	Lundbeck & Co As H	Metodo para la preparacion de escitalopram

2003
- 2003-12-18 US US10/540,300 patent/US7390913B2/en not_active Expired - Fee Related
- 2003-12-18 EP EP11164841A patent/EP2363389A1/en not_active Withdrawn
- 2003-12-18 NZ NZ540653A patent/NZ540653A/en unknown
- 2003-12-18 PL PL377525A patent/PL207847B1/pl unknown
- 2003-12-18 EP EP03767476A patent/EP1581483B1/en not_active Expired - Lifetime
- 2003-12-18 AU AU2003291960A patent/AU2003291960B2/en not_active Ceased
- 2003-12-18 MX MXPA05006783A patent/MXPA05006783A/es active IP Right Grant
- 2003-12-18 WO PCT/DK2003/000907 patent/WO2004056754A1/en not_active Ceased
- 2003-12-18 JP JP2004561086A patent/JP4505335B2/ja not_active Expired - Lifetime
- 2003-12-18 CA CA2511143A patent/CA2511143C/en not_active Expired - Fee Related
2005
- 2005-06-09 IS IS7886A patent/IS2862B/is unknown
- 2005-06-21 IL IL169330A patent/IL169330A0/en unknown
- 2005-07-25 NO NO20053613A patent/NO331181B1/no not_active IP Right Cessation
2012
- 2012-07-04 CY CY20121100594T patent/CY1112937T1/el unknown

Also Published As

Publication number	Publication date
HK1087994A1 (en)	2006-10-27
MXPA05006783A (es)	2005-09-08
PL377525A1 (pl)	2006-02-06
NO331181B1 (no)	2011-10-24
IS7886A (is)	2005-06-09
EP2363389A1 (en)	2011-09-07
CY1112937T1 (el)	2016-04-13
AU2003291960B2 (en)	2009-11-19
PL207847B1 (pl)	2011-02-28
JP4505335B2 (ja)	2010-07-21
CA2511143C (en)	2011-06-28
EP1581483B1 (en)	2012-06-06
AU2003291960A1 (en)	2004-07-14
IL169330A0 (en)	2009-02-11
NZ540653A (en)	2008-02-29
WO2004056754A1 (en)	2004-07-08
CA2511143A1 (en)	2004-07-08
JP2006511559A (ja)	2006-04-06
EP1581483A1 (en)	2005-10-05
NO20053613D0 (no)	2005-07-25
US7390913B2 (en)	2008-06-24
US20060020140A1 (en)	2006-01-26
IS2862B (is)	2013-12-15

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Legal Events

Date	Code	Title	Description
2008-07-14	CREP	Change of representative	Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104
2024-01-15	MK1K	Patent expired