NO20055026L - Indolonacetamid-derivater, fremgangsmate for fremstilling og anvendelse av disse - Google Patents

Indolonacetamid-derivater, fremgangsmate for fremstilling og anvendelse av disse

Info

Publication number: NO20055026L
Authority: NO; Norway
Prior art keywords: indolone; processes; preparation; acetamide derivatives; acetamide
Prior art date: 2003-03-31

Application number

NO20055026A

Other languages

English (en)

Norwegian (no)

Other versions

NO20055026D0 (no

Inventor

Benoit Kenda

Jean-Philippe Starck

Original Assignee

Ucb Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-31

Filing date

2005-10-28

Publication date

2005-12-22

2005-10-28 Application filed by Ucb Sa filed Critical Ucb Sa

2005-10-28 Publication of NO20055026D0 publication Critical patent/NO20055026D0/no

2005-12-22 Publication of NO20055026L publication Critical patent/NO20055026L/no

Links

AAJVRZILLDSYMG-UHFFFAOYSA-N acetamide;indol-2-one Chemical class CC(N)=O.C1=CC=CC2=NC(=O)C=C21 AAJVRZILLDSYMG-UHFFFAOYSA-N 0.000 title abstract 2
206010010904 Convulsion Diseases 0.000 abstract 2
230000036461 convulsion Effects 0.000 abstract 1
206010015037 epilepsy Diseases 0.000 abstract 1
230000008579 epileptogenesis Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Addiction (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20055026A 2003-03-31 2005-10-28 Indolonacetamid-derivater, fremgangsmate for fremstilling og anvendelse av disse NO20055026L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03007214		2003-03-31
PCT/EP2004/002691 WO2004087658A1 (en)	2003-03-31	2004-03-16	Indolone-acetamide derivatives, processes for preparing them and their uses

Publications (2)

Publication Number	Publication Date
NO20055026D0 NO20055026D0 (no)	2005-10-28
NO20055026L true NO20055026L (no)	2005-12-22

Family

ID=33104041

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20055026A NO20055026L (no)	2003-03-31	2005-10-28	Indolonacetamid-derivater, fremgangsmate for fremstilling og anvendelse av disse

Country Status (18)

Country	Link
US (2)	US7645887B2 (de)
EP (1)	EP1620399B1 (de)
JP (1)	JP2006522041A (de)
KR (1)	KR20050119186A (de)
CN (1)	CN100364973C (de)
AR (1)	AR043959A1 (de)
AT (1)	ATE482193T1 (de)
AU (1)	AU2004226288A1 (de)
BR (1)	BRPI0408863A (de)
CA (1)	CA2520568A1 (de)
DE (1)	DE602004029245D1 (de)
ES (1)	ES2353461T3 (de)
MX (1)	MXPA05009089A (de)
NO (1)	NO20055026L (de)
RU (1)	RU2005131317A (de)
TW (1)	TW200508197A (de)
WO (1)	WO2004087658A1 (de)
ZA (1)	ZA200507231B (de)

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TW200508197A (en)	2003-03-31	2005-03-01	Ucb Sa	Indolone-acetamide derivatives, processes for preparing them and their uses
KR20060129023A (ko) *	2004-02-23	2006-12-14	다이닛본 스미토모 세이야꾸 가부시끼가이샤	신규한 헤테로환 화합물
JP4897679B2 (ja) *	2004-07-22	2012-03-14	ユセベファルマソシエテアノニム	インドロン誘導体、その製造方法及びその使用
JP5597343B2 (ja)	2005-04-28	2014-10-01	エーザイ・アール・アンド・ディー・マネジメント株式会社	抗痴呆薬を含有する組成物
JP2008542323A (ja)	2005-06-01	2008-11-27	ユセベファルマソシエテアノニム	２−オキソ−１−ピロリジン誘導体、その製造方法及びその使用
US7790726B2 (en) *	2005-08-16	2010-09-07	Chemocentryx, Inc.	Monocyclic and bicyclic compounds and methods of use
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WO2008133933A1 (en) *	2007-04-26	2008-11-06	Trustees Of Columbia University In The City Of New York	Methods, systems, and compositions for treating or ameliorating the effects of a non-congenital hypertonia
WO2008132142A2 (en) *	2007-04-27	2008-11-06	Ucb Pharma S.A.	New heterocyclic derivatives useful for the treatment of cns disorders
CA2701594C (en) *	2007-10-24	2014-02-18	Merck Sharp & Dohme Corp.	Heterocycle phenyl amide t-type calcium channel antagonists
US20100249176A1 (en) *	2007-10-24	2010-09-30	Barrow James C	Heterocycle amide t-type calcium channel antagonists
EP3260118B1 (de)	2008-10-16	2021-03-24	The Johns Hopkins University	Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion
US20110212928A1 (en)	2010-02-09	2011-09-01	The Johns Hopkins University	Methods and compositions for improving cognitive function
WO2014078568A1 (en)	2012-11-14	2014-05-22	The Johns Hopkins University	Methods and compositions for treating schizophrenia
EP2968220B1 (de)	2013-03-15	2021-05-05	Agenebio, Inc.	Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen
WO2014144663A1 (en)	2013-03-15	2014-09-18	The Johns Hopkins University	Methods and compositions for improving cognitive function
KR102414246B1 (ko)	2014-01-21	2022-06-27	얀센 파마슈티카 엔.브이.	대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
LT3431106T (lt)	2014-01-21	2021-02-10	Janssen Pharmaceutica Nv	Deriniai, apimantys 2 potipio metabotropinio glutamaterginio receptoriaus teigiamus alosterinius moduliatorius arba ortosterinius agonistus, ir jų panaudojimas
CN107540597A (zh) *	2017-09-22	2018-01-05	苏州大学	N‑乙酰二甲胺基吲哚‑2‑酮衍生物的制备方法
US20210214359A1 (en) *	2018-05-29	2021-07-15	New York University	Compounds and Methods for Treating Bacterial Infections
KR102669101B1 (ko) *	2021-08-10	2024-05-27	충북대학교 산학협력단	신규한 옥소인돌린 기반 아세토히드라지드 및 이를 유효성분으로 포함하는 항암제 조성물
CN114874127B (zh) *	2022-05-23	2023-06-09	中国药科大学	一种二氟羰基化吲哚酮类化合物的制备方法
US20240132513A1 (en)	2022-08-19	2024-04-25	Agenebio, Inc.	Benzazepine derivatives, compositions, and methods for treating cognitive impairment

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TW200508197A (en)	2003-03-31	2005-03-01	Ucb Sa	Indolone-acetamide derivatives, processes for preparing them and their uses
JP4897679B2 (ja) *	2004-07-22	2012-03-14	ユセベファルマソシエテアノニム	インドロン誘導体、その製造方法及びその使用

2004
- 2004-03-15 TW TW093106822A patent/TW200508197A/zh unknown
- 2004-03-16 ES ES04720863T patent/ES2353461T3/es not_active Expired - Lifetime
- 2004-03-16 AT AT04720863T patent/ATE482193T1/de not_active IP Right Cessation
- 2004-03-16 WO PCT/EP2004/002691 patent/WO2004087658A1/en not_active Ceased
- 2004-03-16 BR BRPI0408863-8A patent/BRPI0408863A/pt not_active IP Right Cessation
- 2004-03-16 CA CA002520568A patent/CA2520568A1/en not_active Abandoned
- 2004-03-16 MX MXPA05009089A patent/MXPA05009089A/es not_active Application Discontinuation
- 2004-03-16 KR KR1020057018789A patent/KR20050119186A/ko not_active Withdrawn
- 2004-03-16 CN CNB2004800087283A patent/CN100364973C/zh not_active Expired - Fee Related
- 2004-03-16 JP JP2006504696A patent/JP2006522041A/ja active Pending
- 2004-03-16 AU AU2004226288A patent/AU2004226288A1/en not_active Abandoned
- 2004-03-16 DE DE602004029245T patent/DE602004029245D1/de not_active Expired - Lifetime
- 2004-03-16 US US10/550,667 patent/US7645887B2/en not_active Expired - Fee Related
- 2004-03-16 ZA ZA200507231A patent/ZA200507231B/en unknown
- 2004-03-16 EP EP04720863A patent/EP1620399B1/de not_active Expired - Lifetime
- 2004-03-16 RU RU2005131317/04A patent/RU2005131317A/ru not_active Application Discontinuation
- 2004-03-30 AR ARP040101049A patent/AR043959A1/es not_active Application Discontinuation
2005
- 2005-10-28 NO NO20055026A patent/NO20055026L/no not_active Application Discontinuation
2009
- 2009-11-20 US US12/622,533 patent/US7964593B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2004087658A1 (en)	2004-10-14
ATE482193T1 (de)	2010-10-15
US7964593B2 (en)	2011-06-21
US7645887B2 (en)	2010-01-12
CN1768036A (zh)	2006-05-03
US20100069375A1 (en)	2010-03-18
EP1620399B1 (de)	2010-09-22
NO20055026D0 (no)	2005-10-28
AU2004226288A1 (en)	2004-10-14
JP2006522041A (ja)	2006-09-28
ZA200507231B (en)	2006-11-29
CA2520568A1 (en)	2004-10-14
AR043959A1 (es)	2005-08-17
US20070043038A1 (en)	2007-02-22
KR20050119186A (ko)	2005-12-20
BRPI0408863A (pt)	2006-04-11
HK1089768A1 (zh)	2006-12-08
EP1620399A1 (de)	2006-02-01
ES2353461T3 (es)	2011-03-02
CN100364973C (zh)	2008-01-30
TW200508197A (en)	2005-03-01
DE602004029245D1 (de)	2010-11-04
MXPA05009089A (es)	2005-11-17
RU2005131317A (ru)	2006-02-27

Legal Events

Date	Code	Title	Description
2009-10-26	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20076413L (no)	2008-02-11	Multisykliske forbindelser og fremgangsmater for deres anvendelse
SG161310A1 (en)	2010-05-27	Modulators of indoleamine 2,3-dioxygenase and methods of using the same
TW200621745A (en)	2006-07-01	Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents
TW200612905A (en)	2006-05-01	Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
TW200730515A (en)	2007-08-16	N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
NO20050525L (no)	2005-05-06	Benzimidazol-1-yl-tiofenforbindelser for behandling av cancer
ATE313532T1 (de)	2006-01-15	Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen
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