NO20060022L - Stabile sammensetninger av atorvastatin fremstilt ved vat granulering - Google Patents

Stabile sammensetninger av atorvastatin fremstilt ved vat granulering

Info

Publication number: NO20060022L
Authority: NO; Norway
Prior art keywords: atorvastatin; granulation; cotton; pharmaceutically acceptable; pharmaceutical composition
Prior art date: 2003-06-12

Application number

NO20060022A

Other languages

English (en)

Norwegian (no)

Inventor

Michael Bruce Fergione

Barbara Alice Johnson

Kenneth Craig Waterman

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-12

Filing date

2006-01-03

Publication date

2006-01-03

2006-01-03 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2006-01-03 Publication of NO20060022L publication Critical patent/NO20060022L/no

Links

XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 title abstract 4
XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 title abstract 4
229960005370 atorvastatin Drugs 0.000 title abstract 4
239000000203 mixture Substances 0.000 title abstract 2
229920000742 Cotton Polymers 0.000 title 1
230000003179 granulation Effects 0.000 title 1
238000005469 granulation Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 abstract 3
206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 2
208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
OUCSEDFVYPBLLF-KAYWLYCHSA-N 5-(4-fluorophenyl)-1-[2-[(2r,4r)-4-hydroxy-6-oxooxan-2-yl]ethyl]-n,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@H]2OC(=O)C[C@H](O)C2)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 OUCSEDFVYPBLLF-KAYWLYCHSA-N 0.000 abstract 1
208000024827 Alzheimer disease Diseases 0.000 abstract 1
208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000000654 additive Substances 0.000 abstract 1
230000000996 additive effect Effects 0.000 abstract 1
229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
-1 alkaline earth metal salt Chemical class 0.000 abstract 1
239000007884 disintegrant Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
150000002596 lactones Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Obesity (AREA)
Hematology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Pyrrole Compounds (AREA)

NO20060022A 2003-06-12 2006-01-03 Stabile sammensetninger av atorvastatin fremstilt ved vat granulering NO20060022L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US47811903P	2003-06-12	2003-06-12
PCT/IB2004/001862 WO2004110431A1 (en)	2003-06-12	2004-06-01	Stable compositions of atorvastatin prepared with wet granulation

Publications (1)

Publication Number	Publication Date
NO20060022L true NO20060022L (no)	2006-01-03

Family

ID=33551806

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20060022A NO20060022L (no)	2003-06-12	2006-01-03	Stabile sammensetninger av atorvastatin fremstilt ved vat granulering

Country Status (15)

Country	Link
EP (1)	EP1635814A1 (pt)
JP (1)	JP2006527260A (pt)
KR (1)	KR100814218B1 (pt)
CN (1)	CN100434069C (pt)
AR (1)	AR044774A1 (pt)
AU (1)	AU2004246868B2 (pt)
BR (1)	BRPI0411344A (pt)
CA (1)	CA2465565A1 (pt)
CO (1)	CO5650230A2 (pt)
MX (1)	MXPA05013281A (pt)
NO (1)	NO20060022L (pt)
NZ (1)	NZ543337A (pt)
RU (1)	RU2332211C2 (pt)
TW (1)	TW200503690A (pt)
WO (1)	WO2004110431A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI94339C (fi)	1989-07-21	1995-08-25	Warner Lambert Co	Menetelmä farmaseuttisesti käyttökelpoisen /R-(R,R)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
GB0613925D0 (en) *	2006-07-13	2006-08-23	Unilever Plc	Improvements relating to nanodispersions
WO2009000286A1 (en) *	2007-06-25	2008-12-31	Parmatheen S.A.	Improved pharmaceutical formulation containing an hmg-coa reductase inhibitor and method for the preparation thereof
JP5492790B2 (ja) *	2008-02-27	2014-05-14	トーメンメディカルアーゲー	インプラント及びその製造方法
CN102238941A (zh) *	2008-09-17	2011-11-09	迈兰实验室公司	颗粒、制备它们的方法和包含它们的药物产品
RU2404767C1 (ru) *	2009-08-11	2010-11-27	Закрытое Акционерное Общество "БИОКОМ"	Твердая лекарственная форма, обладающая гиполипидемической и гипохолестеринемической активностью, и способ ее получения
HUP1000299A2 (hu)	2010-06-08	2012-02-28	Nanoform Cardiovascular Therapeutics Ltd	Nanostrukturált Atorvastatint, gyógyszerészetileg elfogadott sóit és kokristályait tartalmazó készítmény és eljárás elõállításukra
WO2013072770A2 (en)	2011-11-15	2013-05-23	Dr. Reddy's Laboratories Ltd.	Pharmaceutical formulations comprising atorvastatin and glimepiride
SMT202500078T1 (it) *	2012-11-02	2025-03-12	Vertex Pharma	Composizioni farmaceutiche per il trattamento di malattie mediate da cftr
CN104069078B (zh) *	2014-05-22	2019-06-11	西藏九瑞健康股份有限公司	阿托伐他汀钙药物组合物及其制备方法
DK3172209T3 (da)	2014-07-25	2021-02-22	Novartis Ag	Tabletformulering med 2-fluor-n-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamid
KR101658350B1 (ko) *	2015-02-06	2016-09-30	경성대학교 산학협력단	고지혈증 치료에 유용한 약학 조성물
BR112017019364B1 (pt) *	2015-03-12	2023-03-21	Dupont Nutrition Usa, Inc	Dispersões sólidas e forma de dosagem de fármacos
EP3437646A4 (en)	2016-03-31	2019-11-27	Intercept Pharmaceuticals, Inc.	ORAL PREPARATION WITH EXTRAORDINARY ELABILITY

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3254219B2 (ja) *	1993-01-19	2002-02-04	ワーナー−ランバート・コンパニー	安定な経口用のｃｉ−９８１製剤およびその製法
JPH06242003A (ja) *	1993-02-12	1994-09-02	Nkk Corp	鉄鋼中のアルミナの粒度測定方法
JP3014040B2 (ja) *	1996-10-30	2000-02-28	信久川野	食物繊維パン及びその製造法
ATE524163T1 (de) *	2000-04-10	2011-09-15	Teva Pharma	Stabile pharmazeutische zusammensetzungen enthaltend 7-substituierte-3,5- dihydroxyheptansäuren oder 7-substituierte-3,5- dihydroxyheptensäuren
US6242003B1 (en) *	2000-04-13	2001-06-05	Novartis Ag	Organic compounds
EP1226818A1 (en) *	2001-01-26	2002-07-31	Pfizer Products Inc.	Pharmaceutical dosage forms with enhanced cohesive and compressibility properties
SI20848A (sl) *	2001-03-14	2002-10-31	Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D.	Farmacevtska formulacija, ki vsebuje atorvastatin kalcij
EP1291017A3 (en) *	2001-09-10	2003-07-02	Warner-Lambert Company	Use of statins to inhibit formation of osteoclasts

2004
- 2004-04-29 CA CA002465565A patent/CA2465565A1/en not_active Abandoned
- 2004-06-01 RU RU2005136745/15A patent/RU2332211C2/ru not_active IP Right Cessation
- 2004-06-01 EP EP04735614A patent/EP1635814A1/en not_active Withdrawn
- 2004-06-01 NZ NZ543337A patent/NZ543337A/en unknown
- 2004-06-01 KR KR1020057023669A patent/KR100814218B1/ko not_active Expired - Fee Related
- 2004-06-01 BR BRPI0411344-6A patent/BRPI0411344A/pt not_active IP Right Cessation
- 2004-06-01 JP JP2006516512A patent/JP2006527260A/ja active Pending
- 2004-06-01 CN CNB2004800163910A patent/CN100434069C/zh not_active Expired - Fee Related
- 2004-06-01 WO PCT/IB2004/001862 patent/WO2004110431A1/en not_active Ceased
- 2004-06-01 AU AU2004246868A patent/AU2004246868B2/en not_active Ceased
- 2004-06-01 MX MXPA05013281A patent/MXPA05013281A/es not_active Application Discontinuation
- 2004-06-10 AR ARP040102008A patent/AR044774A1/es unknown
- 2004-06-11 TW TW093116894A patent/TW200503690A/zh unknown
2005
- 2005-12-09 CO CO05124741A patent/CO5650230A2/es not_active Application Discontinuation
2006
- 2006-01-03 NO NO20060022A patent/NO20060022L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1635814A1 (en)	2006-03-22
RU2332211C2 (ru)	2008-08-27
CN100434069C (zh)	2008-11-19
CA2465565A1 (en)	2004-12-12
RU2005136745A (ru)	2006-07-27
JP2006527260A (ja)	2006-11-30
WO2004110431A1 (en)	2004-12-23
AU2004246868B2 (en)	2008-01-17
KR20060020666A (ko)	2006-03-06
AU2004246868A1 (en)	2004-12-23
AR044774A1 (es)	2005-10-05
TW200503690A (en)	2005-02-01
NZ543337A (en)	2008-03-28
CO5650230A2 (es)	2006-06-30
BRPI0411344A (pt)	2006-07-11
CN1805741A (zh)	2006-07-19
KR100814218B1 (ko)	2008-03-17
MXPA05013281A (es)	2006-03-09

Legal Events

Date	Code	Title	Description
2010-01-25	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20055185L (no)	2006-03-09	Farmasoytiske sammensetninger omfattende atorvastatin fremstilt uten granulering
MXPA05013281A (es)	2006-03-09	Composiciones farmaceuticas de atorvastatina.
WO2005034908A3 (en)	2005-08-11	A solid dosage form comprising a fibrate and a statin
EA200001125A1 (ru)	2001-04-23	Гелеобразные фармацевтические композиции
PL309721A1 (en)	1996-01-22	Pharmaceutical composition containing fluoxetin hydrochloride
MXPA05012955A (es)	2006-02-13	Composiciones farmaceuticas de atorvastatina.
AU2721402A (en)	2002-06-18	Anilinopyrimidine derivatives as jnk pathway inhibitors and compositions and methods related thereto
NO20061640L (no)	2006-06-12	Hurtig opplosningspreparat av en kalsiumreseptiraktiv forbindelse
BE2015C026I2 (en)	2018-08-24	2-phenyl-1-[-(2-aminoethoxy)-benzyl -indole in combination with estrogens
NO20064670L (no)	2006-10-16	Galeniske formuleringer av organiske forbindelser
LU92166I2 (fr)	2014-03-13	Glycopyrronium ou un de ses sels
WO2002015662A3 (en)	2002-06-13	Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists
MY129798A (en)	2007-04-30	Process for preparing a pharmaceutical composition
MY144992A (en)	2011-12-15	Substituted 1,2,3,4-tetrahydroisoquinoline derivatives.
MEP33708A (hr)	2010-10-10	Farmaceutske smješe koje obuhvataju inhibitor hmg coa reduktaze
WO2001085257A3 (en)	2002-06-13	Opioid antagonist compositions and dosage forms
MY141661A (en)	2010-05-31	17b-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
MA27809A1 (fr)	2006-03-01	Amides d'acide pyrrolopyridine-2-carboxylique inhibiteurs de glycogene-phosphorylase
EA200200132A1 (ru)	2002-06-27	СЕЛЕКТИВНЫЕ АНТАГОНИСТЫ РЕЦЕПТОРА iGluRДЛЯ ЛЕЧЕНИЯ МИГРЕНИ
MY138023A (en)	2009-04-30	Compositions and process for preparing cleansing bars comprising low levels of soluble surfactant for enhanced fragrance deposition/longevity
EA200200951A1 (ru)	2003-02-27	Фармацевтические композиции
CA2378834A1 (en)	2001-01-25	Pyrazinones, compositions containing such compounds
TNSN06150A1 (en)	2007-11-15	Tetrazole derivatives and methods of treatment of metabolic-related disorders thereof
EA200100871A1 (ru)	2002-04-25	Кристаллическая форма эплеренона, обладающая повышенной скоростью растворения
JO2231B1 (en)	2004-10-07	Derivatives of Trahydroperan and its use as a therapeutic agent