NO20060733L - Pyrazoliner som PAR-1 antagonister for behandling av kardiovaskulaere sykdommer - Google Patents

Pyrazoliner som PAR-1 antagonister for behandling av kardiovaskulaere sykdommer

Info

Publication number
NO20060733L
NO20060733L NO20060733A NO20060733A NO20060733L NO 20060733 L NO20060733 L NO 20060733L NO 20060733 A NO20060733 A NO 20060733A NO 20060733 A NO20060733 A NO 20060733A NO 20060733 L NO20060733 L NO 20060733L
Authority
NO
Norway
Prior art keywords
pyrazolines
treatment
par
antagonists
cardiovascular diseases
Prior art date
Application number
NO20060733A
Other languages
English (en)
Norwegian (no)
Inventor
Elisabeth Perzborn
Walter Huebsch
Christoph Gerdes
Verena Vohringer
Elke Stahl
Swen Allerheiligen
Nicole Diedrichs
Dirk Brohm
Britta-Nicole Frohlen
Mark Jean Gnoth
Heike Heckroth
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102004010545A external-priority patent/DE102004010545A1/de
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of NO20060733L publication Critical patent/NO20060733L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20060733A 2003-07-15 2006-02-15 Pyrazoliner som PAR-1 antagonister for behandling av kardiovaskulaere sykdommer NO20060733L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10331951 2003-07-15
DE102004010545A DE102004010545A1 (de) 2003-07-15 2004-03-04 Pyrazoline
PCT/EP2004/007227 WO2005007157A1 (de) 2003-07-15 2004-07-02 Pyrazoline als par-1-antagonisten zur behandlung von herz-kreislauf-erkrankungen

Publications (1)

Publication Number Publication Date
NO20060733L true NO20060733L (no) 2006-04-10

Family

ID=34081645

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060733A NO20060733L (no) 2003-07-15 2006-02-15 Pyrazoliner som PAR-1 antagonister for behandling av kardiovaskulaere sykdommer

Country Status (8)

Country Link
EP (1) EP1648447A1 (pt)
AU (1) AU2004257406A1 (pt)
BR (1) BRPI0412554A (pt)
CA (1) CA2532316A1 (pt)
MA (1) MA27905A1 (pt)
MX (1) MXPA06000507A (pt)
NO (1) NO20060733L (pt)
WO (1) WO2005007157A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004061751A1 (de) * 2004-12-22 2006-07-06 Bayer Healthcare Ag Cyanoguanidin-substituierte Pyrazoline
DE102004061748A1 (de) * 2004-12-22 2006-07-06 Bayer Healthcare Ag Azetidin-substituierte Pyrazoline
DE102004061747A1 (de) * 2004-12-22 2006-07-06 Bayer Healthcare Ag Thiophen-substituierte Pyrazoline
ES2722431T3 (es) * 2014-12-08 2019-08-12 Bayer Pharma AG Novedosos compuestos de aril-cianoguanidina
WO2016166186A1 (en) 2015-04-17 2016-10-20 Bayer Pharma Aktiengesellschaft Novel aryl-cyanoguanidine compounds
EP3283478A1 (en) * 2015-04-17 2018-02-21 Bayer Pharma Aktiengesellschaft Novel aryl-cyanoguanidine compounds
EP3109237A1 (en) 2015-06-22 2016-12-28 AnaMar AB Novel 5-ht2 antagonists
CN111892585A (zh) * 2020-08-05 2020-11-06 杭州维坦医药科技有限公司 作为p2x3受体拮抗剂的n-甲酰胺基吡唑啉类衍生物及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69131899T2 (de) * 1990-07-13 2000-08-17 Rohm And Haas Co., Philadelphia N-Aryl-3-aryl-4-substituierte-4,5-dihydro-1H-pyrazol-1-carboxamide und Verfahren zu deren Herstellung
DE4217862A1 (de) * 1991-08-28 1993-03-04 Bayer Ag Substituierte pyrazoline
DE4217863A1 (de) * 1991-08-28 1993-03-04 Bayer Ag Substituierte pyrazoline
DE4217864A1 (de) * 1992-05-29 1993-12-02 Bayer Ag Substituierte Pyrazoline
DE4233713A1 (de) * 1992-10-07 1994-04-14 Bayer Ag Substituierte 4,5-Dihydro-1-pyrazolcarbonsäureanilide

Also Published As

Publication number Publication date
BRPI0412554A (pt) 2006-09-19
WO2005007157A1 (de) 2005-01-27
MXPA06000507A (es) 2006-04-05
CA2532316A1 (en) 2005-01-27
AU2004257406A1 (en) 2005-01-27
EP1648447A1 (de) 2006-04-26
MA27905A1 (fr) 2006-05-02

Similar Documents

Publication Publication Date Title
NO20074592L (no) Acetylenyl-pyrazolo-pyrimidinderivater som mGluR2-antagonister
NO20055421L (no) Kinolinderivater som fosfodiestrase-inhibitorer
NO20060324L (no) [1,8]Naftyridin-2-oner og relaterte forbindelser for behandling av Schizofreni
MX2007000505A (es) Derivados de oxindol sustituidos y medicamentos que contienen los mismos.
NO20051962L (no) Fenetanolaminderivater for behandling av respiratoriske sykdommer
NO20050828L (no) lndol-3-svovelderivater
NO20055649L (no) Substituert dihydrokinazolin med antiviale egenskaper
NO20064201L (no) Glukopyranosylsubstituerte benzolderivater, medikamenter inneholdende slike forbindelser, deres anvendelse og fremstilling
NO20025601L (no) Arylmetylaminderivater for anvendelse som tryptaseinhibitorer
NO20054905L (no) 2-acylamino-4-fenyltiazolderivater, fremgangsmate for deres fremstilling og anvendelse av de samme som i terapeutika
NO20074258L (no) Pyridin-2-karboksamidderivater som MGLUR5 antagonister
ATE365720T1 (de) Agonisten von beta-adrenorezeptoren
NO20041041L (no) Fenetanolaminderivater for behandling av respiratoriske sykdommer
NO20062335L (no) Nye diazaspiroalkaner og deres anvendelse i behandlingen av CCR8 medierte sykdommer
NO20054414L (no) Dihydropteridinoner, metoder for deres fremstilling og bruk av disse som medisiner
NO20092342L (no) Azaspiroderivativater
TW200504067A (en) New substituted imidazo-pyridinones and imidazo-pyridazinones, the preparation thereof and their use as pharmaceutical compositions
NO20066055L (no) Pyridinderivater
NO20051600L (no) 1,4-disubstituerte piperidinderivater og anvendelse derav som 11-betaHSD1 inhibitorer
NO20052796L (no) Indolylpyrazinonderivater anvendelige for behandling av hyper-proliferative forstyrrelser og sykdommer assosiert med angiogenese
NO20056010L (no) Biaryloksymetylaren-karboksylsyrer
MXPA03012013A (es) Derivados de 1-oxa-2,8-diaza-spiro[4,5]dec-2-eno sustituidos como medicamento para el tratamiento de dolor.
NO20082496L (no) Pyrazinderivater
NO20056192L (no) Kapaseinhibitorer og anvendelse derav
NO20061363L (no) Pyrazolo- og imidazo- pyrimidinderivater

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application