NO20061077L - Nye farnesyl-protein-transferaseinbibitorer som antitumormidler - Google Patents
Nye farnesyl-protein-transferaseinbibitorer som antitumormidlerInfo
- Publication number
- NO20061077L NO20061077L NO20061077A NO20061077A NO20061077L NO 20061077 L NO20061077 L NO 20061077L NO 20061077 A NO20061077 A NO 20061077A NO 20061077 A NO20061077 A NO 20061077A NO 20061077 L NO20061077 L NO 20061077L
- Authority
- NO
- Norway
- Prior art keywords
- protein transferase
- farnesyl protein
- antitumor agents
- transferase inhibitors
- compounds
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 239000003528 protein farnesyltransferase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000004357 Transferases Human genes 0.000 abstract 1
- 108090000992 Transferases Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004030 farnesyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Beskrevet er nye trisykliske forbindelser av formel (I) og farmasøytisk akseptable salter eller solvater derav. Forbindelsene er anvendbare for inhibering av farnesylproteintransferase. Også beskrevet er farmasøytiske preparater omfattende forbindelsene av formel (I). Også beskrevet er anvendelse av forbindelsene av formel (I) for fremstilling av et medikament for behandling av kreft.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49326903P | 2003-08-07 | 2003-08-07 | |
| PCT/US2004/025042 WO2005014577A1 (en) | 2003-08-07 | 2004-08-04 | Novel farnesyl protein transferase inhibitors as antitumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061077L true NO20061077L (no) | 2006-05-05 |
Family
ID=36587432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061077A NO20061077L (no) | 2003-08-07 | 2006-03-06 | Nye farnesyl-protein-transferaseinbibitorer som antitumormidler |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1863792A (no) |
| NO (1) | NO20061077L (no) |
| ZA (1) | ZA200601052B (no) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108276328A (zh) * | 2018-03-31 | 2018-07-13 | 山东罗欣药业集团恒欣药业有限公司 | 一种索拉非尼的制备方法 |
-
2004
- 2004-08-04 CN CN 200480029384 patent/CN1863792A/zh active Pending
-
2006
- 2006-02-06 ZA ZA200601052A patent/ZA200601052B/en unknown
- 2006-03-06 NO NO20061077A patent/NO20061077L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1863792A (zh) | 2006-11-15 |
| ZA200601052B (en) | 2007-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |