NO20061292L - Heterosyldiske forbindelser og fremgangsmater for fremstilling og anvendelse derav - Google Patents

Heterosyldiske forbindelser og fremgangsmater for fremstilling og anvendelse derav

Info

Publication number
NO20061292L
NO20061292L NO20061292A NO20061292A NO20061292L NO 20061292 L NO20061292 L NO 20061292L NO 20061292 A NO20061292 A NO 20061292A NO 20061292 A NO20061292 A NO 20061292A NO 20061292 L NO20061292 L NO 20061292L
Authority
NO
Norway
Prior art keywords
compounds
heterosyllic
processes
preparation
compositions
Prior art date
Application number
NO20061292A
Other languages
English (en)
Inventor
Yeleswarapu Koteswar Rao
Manojit Pal
Vedula Manohar Sharma
Akella Venkateswarlu
Ram Pillarisetti
Original Assignee
Reddy Us Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddy Us Therapeutics Inc filed Critical Reddy Us Therapeutics Inc
Publication of NO20061292L publication Critical patent/NO20061292L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
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    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

Forbindelser med formel (I) og fremgangsmåte og/eller sammensetninger som innbefatter forbindelser som er effektive når det gjelder å modulere inflammasjonsresponser, slik som de som er resultat av AGE og glykatert proteinakkumulering er tilveiebrakt. Fremgangsmåte og/eller sammensetninger som innbefatter forbindelser som er effektive når det gjelder å modulere glattmuskelcelleproliferasjon og sykdommer eller tilstander relatert dertil, er også tilveiebrakt.
NO20061292A 2003-10-28 2006-03-21 Heterosyldiske forbindelser og fremgangsmater for fremstilling og anvendelse derav NO20061292L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN861CH2003 2003-10-28
US61016304P 2004-09-15 2004-09-15
PCT/US2004/035939 WO2005042712A2 (en) 2003-10-28 2004-10-28 Heterocyclic compounds and methods of making and using thereof

Publications (1)

Publication Number Publication Date
NO20061292L true NO20061292L (no) 2006-07-28

Family

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Application Number Title Priority Date Filing Date
NO20061292A NO20061292L (no) 2003-10-28 2006-03-21 Heterosyldiske forbindelser og fremgangsmater for fremstilling og anvendelse derav

Country Status (9)

Country Link
EP (1) EP1678157A4 (no)
JP (2) JP2007509966A (no)
KR (1) KR20070026306A (no)
AU (1) AU2004286277A1 (no)
CA (1) CA2540460A1 (no)
IL (1) IL174249A0 (no)
NO (1) NO20061292L (no)
RU (1) RU2006112343A (no)
WO (1) WO2005042712A2 (no)

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AU2004286277A1 (en) * 2003-10-28 2005-05-12 Reddy Us Therapeutics, Inc. Heterocyclic compounds and methods of making and using thereof
CA2617213C (en) * 2005-07-29 2014-01-28 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
WO2008092231A1 (en) 2007-02-01 2008-08-07 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
AU2010204106B2 (en) 2009-01-08 2014-05-08 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
KR20190091564A (ko) 2009-04-22 2019-08-06 리스버로직스 코퍼레이션 신규한 소염제
CZ2009358A3 (cs) * 2009-06-03 2010-12-15 C3 Bio Gmbh 5,7-Disubstituované 3-isopropylpyrazolo[4,3-d]pyrimidiny pro použití jako lécivo a farmaceutické prípravky tyto látky obsahující
TWI495465B (zh) 2009-09-30 2015-08-11 資生堂股份有限公司 A heparinase activity inhibitor and a wrinkle improving agent and a pharmaceutical composition containing the same
RU2640115C2 (ru) 2011-11-01 2017-12-26 Ресверлоджикс Корп. Фармацевтические композиции замещенных хиназолинонов
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة
DK3439667T3 (da) 2016-04-05 2024-04-02 Immune Sensor Llc Cgas antagonist forbindelser
RU2635112C1 (ru) * 2016-12-12 2017-11-09 федеральное государственное автономное образовательное учреждение высшего образования "Южный федеральный университет" Галогениды 1-(4-трет-бутилфенил)-2-{ 3-[2-(4-фторфенокси)этил]-2-метил-3Н-бензимидазол-1-ил} этанона, обладающие свойством разрывателей поперечных сшивок гликированных белков
KR102941194B1 (ko) * 2018-12-21 2026-03-19 아크룩스 파마슈티컬스, 인크. Dna 폴리머라제 iiic 억제제 및 그의 용도
CN112300141B (zh) * 2020-10-12 2023-04-18 贵州大学 含喹唑啉的杨梅素衍生物、其制备方法及用途
JP7805372B2 (ja) * 2021-03-26 2026-01-23 オルファゲン ファーマシューティカルズ，インク． ピラゾロピリミジノン化合物
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IL174249A0 (en) 2006-08-01
JP2007509966A (ja) 2007-04-19
AU2004286277A1 (en) 2005-05-12
KR20070026306A (ko) 2007-03-08
EP1678157A4 (en) 2009-03-18
JP2008074858A (ja) 2008-04-03
EP1678157A2 (en) 2006-07-12
RU2006112343A (ru) 2007-12-10
WO2005042712A2 (en) 2005-05-12
WO2005042712A3 (en) 2005-07-21

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