NO20063479L - Fosfonater, monofosfonamidater og bis-fosfonamidater for behandling av virussykdommer - Google Patents

Fosfonater, monofosfonamidater og bis-fosfonamidater for behandling av virussykdommer

Info

Publication number
NO20063479L
NO20063479L NO20063479A NO20063479A NO20063479L NO 20063479 L NO20063479 L NO 20063479L NO 20063479 A NO20063479 A NO 20063479A NO 20063479 A NO20063479 A NO 20063479A NO 20063479 L NO20063479 L NO 20063479L
Authority
NO
Norway
Prior art keywords
monophosphonamidates
bisphosphonamidates
phosphonates
treatment
viral diseases
Prior art date
Application number
NO20063479A
Other languages
English (en)
Other versions
NO338001B1 (no
Inventor
Gong-Xin He
William A Lee
Choung U Kim
Jianying Wang
Zheng-Yu Yang
Manoj Desai
Xiaqin Cheng
Gary P Cook
Edward Doerffler
John C Rohloff
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of NO20063479L publication Critical patent/NO20063479L/no
Publication of NO338001B1 publication Critical patent/NO338001B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/664—Amides of phosphorus acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Forbindelser og preparater med formel (I) er beskrevet, anvendbare som antiproliferative midler, og særlig anti-HPV.
NO20063479A 2003-12-30 2006-07-28 Fosfonater, monofosfonamidater og bisfosfonamidater, farmasøytisk preparat derav, og anvendelse derav for fremstilling av et medikament for behandling av tumorer NO338001B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US53374503P 2003-12-30 2003-12-30
US59098704P 2004-07-26 2004-07-26
US60659504P 2004-09-01 2004-09-01
PCT/US2004/043969 WO2005066189A1 (en) 2003-12-30 2004-12-29 Phosphonates, monophosphonamidates, bisphosphonamidates for the treatment of viral diseases

Publications (2)

Publication Number Publication Date
NO20063479L true NO20063479L (no) 2006-10-02
NO338001B1 NO338001B1 (no) 2016-07-18

Family

ID=34753695

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20063479A NO338001B1 (no) 2003-12-30 2006-07-28 Fosfonater, monofosfonamidater og bisfosfonamidater, farmasøytisk preparat derav, og anvendelse derav for fremstilling av et medikament for behandling av tumorer
NO20150615A NO338040B1 (no) 2003-12-30 2015-05-18 Fosfonater, monofosfonamidater og bisfosfonamidater for anvendelse i en metode for behandling av papilloma virus infeksjoner

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20150615A NO338040B1 (no) 2003-12-30 2015-05-18 Fosfonater, monofosfonamidater og bisfosfonamidater for anvendelse i en metode for behandling av papilloma virus infeksjoner

Country Status (27)

Country Link
US (5) US7553825B2 (no)
EP (2) EP2204374B1 (no)
JP (2) JP4949852B2 (no)
KR (2) KR20120080240A (no)
CN (2) CN1950383B (no)
AP (1) AP2212A (no)
AT (1) ATE478082T1 (no)
AU (2) AU2004312546B2 (no)
BR (1) BRPI0418251C1 (no)
CA (1) CA2550222C (no)
CY (2) CY1111050T1 (no)
DE (1) DE602004028763D1 (no)
DK (2) DK1716162T3 (no)
EA (1) EA011304B1 (no)
ES (2) ES2389602T3 (no)
HR (3) HRP20100626T1 (no)
IL (1) IL176407A (no)
IS (1) IS2994B (no)
NO (2) NO338001B1 (no)
NZ (1) NZ548771A (no)
PL (3) PL212403B1 (no)
PT (2) PT1716162E (no)
RS (2) RS52433B (no)
SG (1) SG149075A1 (no)
SI (2) SI1716162T1 (no)
WO (1) WO2005066189A1 (no)
ZA (1) ZA200606049B (no)

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Also Published As

Publication number Publication date
NO20150615L (no) 2005-07-01
US20090291922A1 (en) 2009-11-26
JP2011137029A (ja) 2011-07-14
CA2550222A1 (en) 2005-07-21
EA011304B1 (ru) 2009-02-27
CN1950383A (zh) 2007-04-18
SI1716162T1 (sl) 2010-12-31
IS8516A (is) 2006-06-21
PT2204374E (pt) 2012-09-17
DK1716162T3 (da) 2011-01-10
AP2212A (en) 2011-03-01
CN101816664B (zh) 2012-04-18
US20090149400A1 (en) 2009-06-11
DE602004028763D1 (de) 2010-09-30
KR101214257B1 (ko) 2012-12-21
PL212403B1 (pl) 2012-09-28
JP4949852B2 (ja) 2012-06-13
NO338001B1 (no) 2016-07-18
AU2011200141A1 (en) 2011-02-03
SI2204374T1 (sl) 2012-09-28
BRPI0418251A (pt) 2007-04-17
BRPI0418251C1 (pt) 2021-05-25
US20060030545A1 (en) 2006-02-09
NO338040B1 (no) 2016-07-25
PL380828A1 (pl) 2007-03-19
RS51476B (sr) 2011-04-30
CY1113103T1 (el) 2016-04-13
US8088754B2 (en) 2012-01-03
BRPI0418251B1 (pt) 2019-09-24
PT1716162E (pt) 2010-11-24
ZA200606049B (en) 2008-01-08
EP1716162B1 (en) 2010-08-18
AU2011200141B2 (en) 2012-02-16
US20050222090A1 (en) 2005-10-06
BRPI0418251B8 (pt) 2019-10-08
ATE478082T1 (de) 2010-09-15
HRP20120699T1 (hr) 2012-09-30
HRP20100626T1 (hr) 2011-03-31
CN101816664A (zh) 2010-09-01
US7553825B2 (en) 2009-06-30
EP2204374A1 (en) 2010-07-07
PL1716162T3 (pl) 2011-02-28
IS2994B (is) 2018-03-15
HK1146061A1 (en) 2011-05-13
AU2004312546B2 (en) 2010-10-14
HK1097276A1 (en) 2007-06-22
US8268802B2 (en) 2012-09-18
SG149075A1 (en) 2009-01-29
RS52433B (sr) 2013-02-28
PL2204374T3 (pl) 2012-11-30
ES2389602T3 (es) 2012-10-29
EP2204374B1 (en) 2012-06-13
KR20060129360A (ko) 2006-12-15
JP2007517065A (ja) 2007-06-28
AP2006003675A0 (en) 2006-08-31
EA200601263A1 (ru) 2006-12-29
IL176407A (en) 2012-12-31
CN1950383B (zh) 2010-06-09
CA2550222C (en) 2013-05-28
AU2004312546A1 (en) 2005-07-21
KR20120080240A (ko) 2012-07-16
WO2005066189A1 (en) 2005-07-21
IL176407A0 (en) 2006-10-05
NZ548771A (en) 2010-05-28
HRP20060254A2 (en) 2006-10-31
ES2350983T3 (es) 2011-01-28
US20060046981A1 (en) 2006-03-02
DK2204374T3 (da) 2012-09-10
EP1716162A1 (en) 2006-11-02
CY1111050T1 (el) 2015-06-11

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