NO20061909L - 3-(4-aminofenyl)tienopyrimid-4-on derivater som MCH R-antagonister for behandling av fedme, diabetes,depresjon og angst - Google Patents
3-(4-aminofenyl)tienopyrimid-4-on derivater som MCH R-antagonister for behandling av fedme, diabetes,depresjon og angstInfo
- Publication number
- NO20061909L NO20061909L NO20061909A NO20061909A NO20061909L NO 20061909 L NO20061909 L NO 20061909L NO 20061909 A NO20061909 A NO 20061909A NO 20061909 A NO20061909 A NO 20061909A NO 20061909 L NO20061909 L NO 20061909L
- Authority
- NO
- Norway
- Prior art keywords
- mch
- anxiety
- obesity
- antagonists
- diabetes
- Prior art date
Links
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 230000036506 anxiety Effects 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- LVAGVGLOKJYPSZ-UHFFFAOYSA-N 3-(4-aminophenyl)thieno[3,2-d]pyrimidin-4-one Chemical class C1=CC(N)=CC=C1N1C(=O)C(SC=C2)=C2N=C1 LVAGVGLOKJYPSZ-UHFFFAOYSA-N 0.000 title 1
- 101000581402 Homo sapiens Melanin-concentrating hormone receptor 1 Proteins 0.000 abstract 1
- 102400001132 Melanin-concentrating hormone Human genes 0.000 abstract 1
- 101800002739 Melanin-concentrating hormone Proteins 0.000 abstract 1
- 102000044674 Melanin-concentrating hormone receptor 1 Human genes 0.000 abstract 1
- 150000004982 aromatic amines Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51380003P | 2003-10-23 | 2003-10-23 | |
| PCT/US2004/034846 WO2005042541A1 (fr) | 2003-10-23 | 2004-10-21 | Derives de 3-(4-aminophenyl)-thienopyrimid-4-one utilises comme antagonistes de mch r1 pour le traitement de l'obesite, du diabete, de la depression et de l'anxiete |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061909L true NO20061909L (no) | 2006-05-03 |
Family
ID=34549304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061909A NO20061909L (no) | 2003-10-23 | 2006-04-28 | 3-(4-aminofenyl)tienopyrimid-4-on derivater som MCH R-antagonister for behandling av fedme, diabetes,depresjon og angst |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20070078125A1 (fr) |
| EP (1) | EP1678184A1 (fr) |
| JP (1) | JP2007509158A (fr) |
| KR (1) | KR20060100412A (fr) |
| CN (1) | CN1871242A (fr) |
| AU (1) | AU2004285913A1 (fr) |
| BR (1) | BRPI0415667A (fr) |
| CA (1) | CA2543122A1 (fr) |
| CO (1) | CO5690599A2 (fr) |
| IL (1) | IL174693A0 (fr) |
| MA (1) | MA28111A1 (fr) |
| MX (1) | MXPA06003997A (fr) |
| NO (1) | NO20061909L (fr) |
| WO (1) | WO2005042541A1 (fr) |
| ZA (1) | ZA200603181B (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080221107A1 (en) * | 2005-07-15 | 2008-09-11 | Astrazeneca Ab | Therapeutic Agents |
| AU2006298852A1 (en) | 2005-09-30 | 2007-04-12 | F. Hoffmann-La Roche Ag | Indane derivatives as MCH receptor antagonists |
| US8618115B2 (en) * | 2005-10-26 | 2013-12-31 | Bristol-Myers Squibb Company | Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them |
| US7745447B2 (en) | 2005-10-26 | 2010-06-29 | Bristol-Myers Squibb Company | Substituted thieno[3,2-D]pyrimidines as non-basic melanin concentrating hormone receptor-1 antagonists |
| JP5193878B2 (ja) | 2005-12-21 | 2013-05-08 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｍｃｈ−１が媒介する疾患における使用のための新規な置換ピラジノン誘導体 |
| US7553836B2 (en) | 2006-02-06 | 2009-06-30 | Bristol-Myers Squibb Company | Melanin concentrating hormone receptor-1 antagonists |
| TW200801022A (en) | 2006-02-15 | 2008-01-01 | Sanofi Aventis | Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments |
| ATE495157T1 (de) | 2006-02-15 | 2011-01-15 | Sanofi Aventis | Neue aminoalkohol-substituierte aryldihydroisochinolinone, herstellungsverfahren und ihre verwendung als medikamente |
| JP5175228B2 (ja) | 2006-02-15 | 2013-04-03 | サノフイ | 新規なアザシクリル置換アリールジヒドロイソキノリノン、それらの製造方法及び薬剤としてそれらの使用 |
| JP2009526792A (ja) * | 2006-02-15 | 2009-07-23 | サノフィ−アベンティス | 新規なアザシクリル置換アリールチエノピリミジノン、それらの製造方法及び薬剤としてのそれらの使用 |
| CN101454328A (zh) * | 2006-06-08 | 2009-06-10 | 伊莱利利公司 | 新的mch受体拮抗剂 |
| JP2010501553A (ja) | 2006-08-18 | 2010-01-21 | アストラゼネカ アクチボラグ | Ｍｃｈｒ１アンタゴニストとしてのチエノピリミジン−４−オン誘導体およびチエノピリダジン−７−オン誘導体 |
| BRPI0806537A2 (pt) | 2007-01-10 | 2014-04-22 | Albany Molecular Res Inc | Indazóis substituídos por 5-piridinona |
| WO2008134480A1 (fr) * | 2007-04-25 | 2008-11-06 | Bristol-Myers Squibb Company | Antagonistes du récepteur 1 de l'hormone de mélano-concentration non basiques |
| ATE544759T1 (de) | 2007-07-21 | 2012-02-15 | Albany Molecular Res Inc | 5-pyridinon-substituierte indazole und pharmazeutische zusammensetzungen davon |
| PE20091928A1 (es) | 2008-05-29 | 2009-12-31 | Bristol Myers Squibb Co | Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos |
| US8278316B2 (en) | 2009-03-09 | 2012-10-02 | Bristol-Myers Squibb Company | Aza pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists |
| HUP1100241A3 (en) | 2011-05-06 | 2013-12-30 | Richter Gedeon Nyrt | Oxetane substituted pyrimidones |
| KR20130013199A (ko) * | 2011-07-27 | 2013-02-06 | 한미약품 주식회사 | 신규 피리미딘 유도체 및 이를 활성성분으로 포함하는 약학 조성물 |
| WO2013032535A1 (fr) | 2011-08-26 | 2013-03-07 | O'neil Michael P | Système et procédé de détatouage |
| AU2021206286A1 (en) * | 2020-01-10 | 2024-08-08 | Consynance Therapeutics, Inc. | Therapeutic combinations of drugs and methods of using them |
| HUP2200222A1 (hu) | 2022-06-17 | 2023-12-28 | Richter Gedeon Nyrt | MCHR1 antagonisták a Prader-Willi szindróma kezelésére |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0124627D0 (en) * | 2001-10-15 | 2001-12-05 | Smithkline Beecham Plc | Novel compounds |
-
2004
- 2004-10-21 CA CA002543122A patent/CA2543122A1/fr not_active Abandoned
- 2004-10-21 BR BRPI0415667-6A patent/BRPI0415667A/pt not_active IP Right Cessation
- 2004-10-21 EP EP04795941A patent/EP1678184A1/fr not_active Withdrawn
- 2004-10-21 JP JP2006536779A patent/JP2007509158A/ja active Pending
- 2004-10-21 MX MXPA06003997A patent/MXPA06003997A/es unknown
- 2004-10-21 AU AU2004285913A patent/AU2004285913A1/en not_active Abandoned
- 2004-10-21 KR KR1020067009417A patent/KR20060100412A/ko not_active Withdrawn
- 2004-10-21 CN CNA2004800313000A patent/CN1871242A/zh active Pending
- 2004-10-21 US US10/576,765 patent/US20070078125A1/en not_active Abandoned
- 2004-10-21 WO PCT/US2004/034846 patent/WO2005042541A1/fr not_active Ceased
-
2006
- 2006-03-30 IL IL174693A patent/IL174693A0/en unknown
- 2006-04-20 ZA ZA200603181A patent/ZA200603181B/en unknown
- 2006-04-21 CO CO06038136A patent/CO5690599A2/es not_active Application Discontinuation
- 2006-04-25 MA MA28965A patent/MA28111A1/fr unknown
- 2006-04-28 NO NO20061909A patent/NO20061909L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1678184A1 (fr) | 2006-07-12 |
| ZA200603181B (en) | 2008-01-30 |
| MA28111A1 (fr) | 2006-08-01 |
| AU2004285913A1 (en) | 2005-05-12 |
| JP2007509158A (ja) | 2007-04-12 |
| IL174693A0 (en) | 2006-08-20 |
| KR20060100412A (ko) | 2006-09-20 |
| CN1871242A (zh) | 2006-11-29 |
| US20070078125A1 (en) | 2007-04-05 |
| CO5690599A2 (es) | 2006-10-31 |
| BRPI0415667A (pt) | 2006-12-19 |
| WO2005042541A1 (fr) | 2005-05-12 |
| MXPA06003997A (es) | 2006-07-05 |
| CA2543122A1 (fr) | 2005-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |