NO20063268L - Fremgangsmate til fremstilling av 1-(2S,3S)-2-benzhydryl-N-(5-tert-butyl-2-metoksybenzyl)quinuklidin-3-amin - Google Patents
Fremgangsmate til fremstilling av 1-(2S,3S)-2-benzhydryl-N-(5-tert-butyl-2-metoksybenzyl)quinuklidin-3-aminInfo
- Publication number
- NO20063268L NO20063268L NO20063268A NO20063268A NO20063268L NO 20063268 L NO20063268 L NO 20063268L NO 20063268 A NO20063268 A NO 20063268A NO 20063268 A NO20063268 A NO 20063268A NO 20063268 L NO20063268 L NO 20063268L
- Authority
- NO
- Norway
- Prior art keywords
- quinuclidin
- benzhydryl
- methoxybenzyl
- amine
- butyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- REUAXQZIRFXQML-UHFFFAOYSA-N 1-azabicyclo[2.2.2]octan-3-amine Chemical compound C1CC2C(N)CN1CC2 REUAXQZIRFXQML-UHFFFAOYSA-N 0.000 abstract 1
- YASYEJJMZJALEJ-UHFFFAOYSA-N Citric acid monohydrate Chemical compound O.OC(=O)CC(O)(C(O)=O)CC(O)=O YASYEJJMZJALEJ-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54132304P | 2004-02-02 | 2004-02-02 | |
| PCT/IB2005/000221 WO2005075473A1 (en) | 2004-02-02 | 2005-01-26 | Process for preparation of 1-(2s,3s)-2-benzhydr yl-n-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20063268L true NO20063268L (no) | 2006-08-15 |
Family
ID=34837478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20063268A NO20063268L (no) | 2004-02-02 | 2006-07-13 | Fremgangsmate til fremstilling av 1-(2S,3S)-2-benzhydryl-N-(5-tert-butyl-2-metoksybenzyl)quinuklidin-3-amin |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20090099364A1 (pl) |
| EP (1) | EP1713801B1 (pl) |
| JP (1) | JP2007519710A (pl) |
| KR (1) | KR100812046B1 (pl) |
| CN (1) | CN1914202A (pl) |
| AR (1) | AR047523A1 (pl) |
| AT (1) | ATE380811T1 (pl) |
| AU (1) | AU2005210259A1 (pl) |
| BR (1) | BRPI0507334A (pl) |
| CA (1) | CA2554360A1 (pl) |
| CY (1) | CY1107141T1 (pl) |
| DE (1) | DE602005003791T2 (pl) |
| DK (1) | DK1713801T3 (pl) |
| ES (1) | ES2296131T3 (pl) |
| IL (1) | IL176817A0 (pl) |
| NO (1) | NO20063268L (pl) |
| PL (1) | PL1713801T3 (pl) |
| PT (1) | PT1713801E (pl) |
| RU (1) | RU2320659C9 (pl) |
| SI (1) | SI1713801T1 (pl) |
| WO (1) | WO2005075473A1 (pl) |
| ZA (1) | ZA200605784B (pl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5021318B2 (ja) | 2004-01-30 | 2012-09-05 | ファイザー・プロダクツ・インク | β−シクロデキストリンを液体投薬形態に用いて多用量製剤を達成するための抗菌性防腐剤 |
| EP2571847B1 (en) | 2010-05-19 | 2016-09-21 | Sandoz AG | Process for the preparation of chiral hydrazides |
| RU2585683C2 (ru) | 2010-05-19 | 2016-06-10 | Сандоз Аг | Очистка позаконазола и промежуточных продуктов для синтеза позаконазола |
| CN102892762B (zh) | 2010-05-19 | 2016-04-20 | 桑多斯股份公司 | 制备泊沙康唑中间体 |
| US9446029B2 (en) | 2010-07-27 | 2016-09-20 | Colorado State University Research Foundation | Use of NK-1 receptor antagonists in management of visceral pain |
| DE102011100534A1 (de) | 2011-05-05 | 2012-11-08 | Howaldtswerke-Deutsche Werft Gmbh | Verfahren zum Betreiben einer Reformer-Brennstoffzellenanlage |
| CN103635465A (zh) | 2011-06-16 | 2014-03-12 | 桑多斯股份公司 | 制备手性化合物的方法 |
| CN108341811A (zh) * | 2017-01-23 | 2018-07-31 | 科贝源(北京)生物医药科技有限公司 | 马罗皮坦杂质的制备方法 |
| CN108341812A (zh) * | 2017-01-23 | 2018-07-31 | 科贝源(北京)生物医药科技有限公司 | 一种含奎宁环化合物的制备方法 |
| CN106977512B (zh) * | 2017-05-04 | 2019-01-01 | 海门慧聚药业有限公司 | 制备马罗匹坦游离碱的方法 |
| CN110577522B (zh) * | 2018-06-07 | 2022-12-27 | 东莞市东阳光动物保健药品有限公司 | 马罗匹坦柠檬酸盐新晶型及其制备方法 |
| CN109320510B (zh) * | 2018-11-27 | 2021-04-27 | 江苏慧聚药业有限公司 | 一种马罗匹坦游离碱的制备方法 |
| CN112979639B (zh) * | 2019-12-16 | 2025-08-08 | 凯默斯医药科技(上海)有限公司 | 一种马罗皮坦新晶型及其制备方法 |
| KR102666745B1 (ko) * | 2023-09-06 | 2024-05-17 | 주식회사 에스아이켐 | 시선 유도봉 및 표지병의 노면부착용 에폭시계 접착제 조성물 및 이를 이용한 시선 유도봉 및 표지병의 시공방법 |
| WO2025172911A1 (en) * | 2024-02-16 | 2025-08-21 | Teadus Pharmaceuticals Pvt. Ltd | A process for the preparation of (2s,3s)-2-benzhydryl- n-(5-tert-butyl-2-methoxybenzyl) quinuclidin-3-amine and pharmaceutically acceptable salts thereof |
| CN119285626B (zh) * | 2024-10-11 | 2025-12-09 | 中国农业大学 | 一种止呕药化合物的制备方法及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA27776C2 (uk) * | 1991-05-31 | 2000-10-16 | Пфайзер Інк. | Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців |
| US5393762A (en) * | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
| PE8798A1 (es) * | 1995-07-17 | 1998-03-02 | Pfizer | Procedimiento de separacion de los enantiomeros del 1-azabiciclo[2.2.2] octan-3-amina, 2-(difenilmetil) -n- [[2-metoxi-5-(1-metiletil) fenil] metil] |
| US6255320B1 (en) * | 1999-06-01 | 2001-07-03 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions |
| US6861526B2 (en) * | 2002-10-16 | 2005-03-01 | Pfizer Inc. | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine |
-
2005
- 2005-01-26 KR KR1020067015573A patent/KR100812046B1/ko not_active Expired - Fee Related
- 2005-01-26 ES ES05702373T patent/ES2296131T3/es not_active Expired - Lifetime
- 2005-01-26 DE DE602005003791T patent/DE602005003791T2/de not_active Expired - Fee Related
- 2005-01-26 WO PCT/IB2005/000221 patent/WO2005075473A1/en not_active Ceased
- 2005-01-26 CA CA002554360A patent/CA2554360A1/en not_active Abandoned
- 2005-01-26 AU AU2005210259A patent/AU2005210259A1/en not_active Abandoned
- 2005-01-26 RU RU2006127969/04A patent/RU2320659C9/ru not_active IP Right Cessation
- 2005-01-26 JP JP2006550351A patent/JP2007519710A/ja not_active Withdrawn
- 2005-01-26 DK DK05702373T patent/DK1713801T3/da active
- 2005-01-26 AT AT05702373T patent/ATE380811T1/de not_active IP Right Cessation
- 2005-01-26 CN CNA2005800038987A patent/CN1914202A/zh active Pending
- 2005-01-26 PL PL05702373T patent/PL1713801T3/pl unknown
- 2005-01-26 EP EP05702373A patent/EP1713801B1/en not_active Expired - Lifetime
- 2005-01-26 BR BRPI0507334-0A patent/BRPI0507334A/pt not_active IP Right Cessation
- 2005-01-26 PT PT05702373T patent/PT1713801E/pt unknown
- 2005-01-26 SI SI200530124T patent/SI1713801T1/sl unknown
- 2005-01-26 US US10/588,049 patent/US20090099364A1/en not_active Abandoned
- 2005-01-31 AR ARP050100351A patent/AR047523A1/es not_active Application Discontinuation
-
2006
- 2006-07-12 IL IL176817A patent/IL176817A0/en unknown
- 2006-07-13 ZA ZA200605784A patent/ZA200605784B/en unknown
- 2006-07-13 NO NO20063268A patent/NO20063268L/no not_active Application Discontinuation
-
2008
- 2008-01-15 CY CY20081100055T patent/CY1107141T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005003791D1 (de) | 2008-01-24 |
| US20090099364A1 (en) | 2009-04-16 |
| PT1713801E (pt) | 2008-02-11 |
| DE602005003791T2 (de) | 2008-05-29 |
| EP1713801B1 (en) | 2007-12-12 |
| KR100812046B1 (ko) | 2008-03-10 |
| SI1713801T1 (sl) | 2008-04-30 |
| DK1713801T3 (da) | 2008-03-17 |
| CY1107141T1 (el) | 2012-10-24 |
| AU2005210259A1 (en) | 2005-08-18 |
| CA2554360A1 (en) | 2005-08-18 |
| KR20060127966A (ko) | 2006-12-13 |
| EP1713801A1 (en) | 2006-10-25 |
| PL1713801T3 (pl) | 2008-04-30 |
| ES2296131T3 (es) | 2008-04-16 |
| RU2320659C9 (ru) | 2008-07-20 |
| IL176817A0 (en) | 2006-10-31 |
| CN1914202A (zh) | 2007-02-14 |
| AR047523A1 (es) | 2006-01-25 |
| ATE380811T1 (de) | 2007-12-15 |
| BRPI0507334A (pt) | 2007-07-03 |
| JP2007519710A (ja) | 2007-07-19 |
| RU2320659C1 (ru) | 2008-03-27 |
| ZA200605784B (en) | 2007-11-28 |
| WO2005075473A1 (en) | 2005-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |