NO20070445L - Pyrimidinderivater. - Google Patents

Pyrimidinderivater.

Info

Publication number
NO20070445L
NO20070445L NO20070445A NO20070445A NO20070445L NO 20070445 L NO20070445 L NO 20070445L NO 20070445 A NO20070445 A NO 20070445A NO 20070445 A NO20070445 A NO 20070445A NO 20070445 L NO20070445 L NO 20070445L
Authority
NO
Norway
Prior art keywords
pyrimidine
esters
compounds
formula
disclosed
Prior art date
Application number
NO20070445A
Other languages
English (en)
Norwegian (no)
Inventor
Werner Neidhart
Daniel Hunziker
Bernd Kuhn
Alexander Mayweg
Kurt Amrein
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20070445L publication Critical patent/NO20070445L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69Benzenesulfonamido-pyrimidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20070445A 2004-06-28 2007-01-24 Pyrimidinderivater. NO20070445L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04102999 2004-06-28
PCT/EP2005/006649 WO2006000371A2 (fr) 2004-06-28 2005-06-20 Derives de pyrimidine

Publications (1)

Publication Number Publication Date
NO20070445L true NO20070445L (no) 2007-01-24

Family

ID=35478760

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070445A NO20070445L (no) 2004-06-28 2007-01-24 Pyrimidinderivater.

Country Status (22)

Country Link
US (1) US7507733B2 (fr)
EP (1) EP1763517B1 (fr)
JP (1) JP4809339B2 (fr)
CN (1) CN1972918B (fr)
AR (1) AR049699A1 (fr)
AT (1) ATE509011T1 (fr)
AU (1) AU2005256442B2 (fr)
BR (1) BRPI0512705A (fr)
CA (1) CA2571361C (fr)
DK (1) DK1763517T3 (fr)
ES (1) ES2362884T3 (fr)
IL (1) IL179914A0 (fr)
MX (1) MXPA06014892A (fr)
MY (1) MY143568A (fr)
NO (1) NO20070445L (fr)
NZ (1) NZ551859A (fr)
PL (1) PL1763517T3 (fr)
PT (1) PT1763517E (fr)
RU (1) RU2375351C2 (fr)
TW (1) TWI299040B (fr)
WO (1) WO2006000371A2 (fr)
ZA (1) ZA200610415B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1866298A2 (fr) * 2005-03-31 2007-12-19 Takeda San Diego, Inc. Inhibiteurs de l'hydroxysteroide deshydrogenase
WO2007092435A2 (fr) * 2006-02-07 2007-08-16 Wyeth Inhibiteurs 11-beta hsd1
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
EP2046753A2 (fr) * 2006-07-06 2009-04-15 Brystol-Myers Squibb Company Inhibiteurs de type i de la 11-bêta hydroxystéroïde déshydrogénase pyridone/hydroxypyridine
TW200827346A (en) 2006-11-03 2008-07-01 Astrazeneca Ab Chemical compounds
TW200836719A (en) 2007-02-12 2008-09-16 Astrazeneca Ab Chemical compounds
CL2008001839A1 (es) 2007-06-21 2009-01-16 Incyte Holdings Corp Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades.
US20100022572A1 (en) 2008-07-18 2010-01-28 Kowa Company, Ltd. Novel spiro compound and medicine comprising the same
JP5693452B2 (ja) * 2008-08-04 2015-04-01 シーエイチディーアイ ファウンデーション,インコーポレーテッド 特定のキヌレニン−3−モノオキシゲナーゼインヒビター、医薬組成物およびそれらの使用方法
US8236789B2 (en) 2008-08-29 2012-08-07 Kowa Company, Ltd. 1-adamantyl azetidin-2-one derivatives and drugs containing same
JP5477973B2 (ja) 2008-10-29 2014-04-23 興和株式会社 1,2−ジアゼチジン−3−オン誘導体及びこれを含有する医薬
CA2787365A1 (fr) 2010-01-25 2011-07-28 Chdi Foundation, Inc. Certains inhibiteurs de kynurenine-3-monooxygenase, compositions pharmaceutiques, et procedes d'utilisation de ceux-ci
WO2012051139A1 (fr) * 2010-10-15 2012-04-19 Amgen Inc. Nouvelles utilisations de 2-amino-thiazolones substituées dans traitement de la maladie d'alzheimer
WO2012102366A1 (fr) * 2011-01-28 2012-08-02 日本たばこ産業株式会社 Procédé de production d'un nouveau composé de pipérazine
KR20140072037A (ko) 2011-08-30 2014-06-12 씨에이치디아이 파운데이션, 인코포레이티드 키뉴레닌-3-모노옥시게나제 억제제, 약학적 조성물 및 이의 사용 방법
SI2750677T1 (sl) 2011-08-30 2017-10-30 Chdi Foundation, Inc. Inhibitorji kinurenin-3-monooksigenaze, farmacevtski sestavki in postopki njihove uporabe
TW201512171A (zh) 2013-04-19 2015-04-01 Pfizer Ltd 化學化合物
AU2015289492B2 (en) 2014-07-17 2020-02-20 Chdi Foundation, Inc. Methods and compositions for treating HIV-related disorders
WO2017160922A1 (fr) 2016-03-16 2017-09-21 Kalyra Pharmaceuticals, Inc. Composés analgésiques
EP3235813A1 (fr) 2016-04-19 2017-10-25 Cidqo 2012, S.L. Dérivés aza-tétra-cycliques

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1229413A (fr) * 1967-06-14 1971-04-21
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
JP2744663B2 (ja) * 1988-12-29 1998-04-28 三井化学株式会社 ピリミジン類及びその薬学的に許容される塩類
TW287160B (fr) * 1992-12-10 1996-10-01 Hoffmann La Roche
TW394761B (en) 1993-06-28 2000-06-21 Hoffmann La Roche Novel Sulfonylamino Pyrimidines
SE0001899D0 (sv) * 2000-05-22 2000-05-22 Pharmacia & Upjohn Ab New compounds
NZ566263A (en) * 2002-05-24 2009-09-25 Millennium Pharm Inc CCR9 inhibitors and methods of use thereof
AU2005236055B2 (en) * 2004-04-20 2011-10-06 Transtech Pharma, Llc Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators

Also Published As

Publication number Publication date
RU2007103303A (ru) 2008-08-10
AR049699A1 (es) 2006-08-30
US7507733B2 (en) 2009-03-24
ES2362884T3 (es) 2011-07-14
DK1763517T3 (da) 2011-06-06
ATE509011T1 (de) 2011-05-15
TWI299040B (en) 2008-07-21
JP4809339B2 (ja) 2011-11-09
HK1104553A1 (zh) 2008-01-18
CA2571361A1 (fr) 2006-01-05
EP1763517A2 (fr) 2007-03-21
PT1763517E (pt) 2011-07-01
JP2008504321A (ja) 2008-02-14
ZA200610415B (en) 2008-06-25
CA2571361C (fr) 2011-07-26
IL179914A0 (en) 2007-05-15
US20050288308A1 (en) 2005-12-29
AU2005256442B2 (en) 2009-02-12
RU2375351C2 (ru) 2009-12-10
BRPI0512705A (pt) 2008-04-01
EP1763517B1 (fr) 2011-05-11
WO2006000371A2 (fr) 2006-01-05
MY143568A (en) 2011-05-31
PL1763517T3 (pl) 2011-10-31
TW200616976A (en) 2006-06-01
WO2006000371A3 (fr) 2006-04-27
NZ551859A (en) 2010-05-28
MXPA06014892A (es) 2007-02-28
CN1972918B (zh) 2010-10-13
CN1972918A (zh) 2007-05-30
AU2005256442A1 (en) 2006-01-05

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