NO20071232L - Indolylmaleimide derivatives as protein kinase C inhibitors - Google Patents
Indolylmaleimide derivatives as protein kinase C inhibitorsInfo
- Publication number
- NO20071232L NO20071232L NO20071232A NO20071232A NO20071232L NO 20071232 L NO20071232 L NO 20071232L NO 20071232 A NO20071232 A NO 20071232A NO 20071232 A NO20071232 A NO 20071232A NO 20071232 L NO20071232 L NO 20071232L
- Authority
- NO
- Norway
- Prior art keywords
- inhibitors
- protein kinase
- indolylmaleimide derivatives
- indolylmaleimide
- derivatives
- Prior art date
Links
- WIQRSJOCVVPMPS-UHFFFAOYSA-N 3-(1h-indol-2-yl)pyrrole-2,5-dione Chemical class O=C1NC(=O)C(C=2NC3=CC=CC=C3C=2)=C1 WIQRSJOCVVPMPS-UHFFFAOYSA-N 0.000 title abstract 2
- 229940123924 Protein kinase C inhibitor Drugs 0.000 title 1
- 239000003881 protein kinase C inhibitor Substances 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000017667 Chronic Disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 125000005956 isoquinolyl group Chemical group 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- -1 naffyl Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000002294 quinazolinyl group Chemical group N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Indolylmaleimidderivater irmbefattende enten en substituert fenyl-, naffyl-, tetrahydronaftyl-, kinazolinyl-, kinolyl-, isokinolyl- eller pyrimidinylrest som har interessante farmasøytiske egenskaper, for eksempel i behandling og/eller forebyggelse av T-celleformidlede, akutte eller kroniske, inflammatoriske sykdommer eller forstyrrelser, autoimmunsykdommer, transplantatrejeksjon eller kreft.Indolylmaleimide derivatives comprising either a substituted phenyl, naffyl, tetrahydronaphthyl, quinazolinyl, quinolyl, isoquinolyl or pyrimidinyl residue having interesting pharmaceutical properties, for example in the treatment and / or prevention of T-cell mediated, acute or chronic, inflammatory or chronic disorders, autoimmune diseases, graft rejection or cancer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24640000P | 2000-11-07 | 2000-11-07 | |
| PCT/EP2001/012785 WO2002038561A1 (en) | 2000-11-07 | 2001-11-05 | Indolylmaleimide derivatives as protein kinase c inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20071232L true NO20071232L (en) | 2003-07-04 |
Family
ID=33449385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071232A NO20071232L (en) | 2000-11-07 | 2007-03-06 | Indolylmaleimide derivatives as protein kinase C inhibitors |
Country Status (3)
| Country | Link |
|---|---|
| EC (1) | ECSP034578A (en) |
| NO (1) | NO20071232L (en) |
| ZA (1) | ZA200303426B (en) |
-
2003
- 2003-05-05 ZA ZA200303426A patent/ZA200303426B/en unknown
- 2003-05-07 EC ECSP034578 patent/ECSP034578A/en unknown
-
2007
- 2007-03-06 NO NO20071232A patent/NO20071232L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200303426B (en) | 2004-04-22 |
| ECSP034578A (en) | 2003-06-25 |
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