NO20071426L - Kreft kombinasjonsbehandling omfattende AZD2171 og Imatinib - Google Patents

Kreft kombinasjonsbehandling omfattende AZD2171 og Imatinib

Info

Publication number
NO20071426L
NO20071426L NO20071426A NO20071426A NO20071426L NO 20071426 L NO20071426 L NO 20071426L NO 20071426 A NO20071426 A NO 20071426A NO 20071426 A NO20071426 A NO 20071426A NO 20071426 L NO20071426 L NO 20071426L
Authority
NO
Norway
Prior art keywords
azd2171
imatinib
human
combination therapy
therapy including
Prior art date
Application number
NO20071426A
Other languages
English (en)
Inventor
Stephen Robert Wedge
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0421436A external-priority patent/GB0421436D0/en
Priority claimed from GB0506725A external-priority patent/GB0506725D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20071426L publication Critical patent/NO20071426L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Foreliggende oppfinnelse angår en fremgangsmåte for frembringelse av en antiangiogen og/eller vaskulær permeabilitetsreduserende effekt hos et varmblodig dyr slik som et menneske som eventuelt blir behandlet med ioniserende stråling, spesielt en fremgangsmåte for behandling av kreft, spesielt kreft som involverer en fast tumor eller en leukemi, som omfatter å administrere AZD2171 i kombinasjon med imatinib; en farmasøytisk blanding omfattende AZD2171 og imatinib; et kombinasjonsprodukt omfattende AZD2171 og imatinib for anvendelse ved en fremgangsmåte for behandling av en menneske- eller dyrekropp ved terapi; et kit omfattende AZD2171 og imatinib; anvendelse av AZD2171 og imatinib ved fremstilling av et medikament for anvendelse ved frembringelse av en antiangiogen og/eller vaskulær permeabilitetsreduserende effekt hos et varmblodig dyr slik som et menneske som eventuelt behandles med ioniserende stråling.
NO20071426A 2004-09-27 2007-03-16 Kreft kombinasjonsbehandling omfattende AZD2171 og Imatinib NO20071426L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0421436A GB0421436D0 (en) 2004-09-27 2004-09-27 Combination therapy
GB0506725A GB0506725D0 (en) 2005-04-01 2005-04-01 Combination therapy
PCT/GB2005/003672 WO2006035203A1 (en) 2004-09-27 2005-09-23 Cancer combination therapy comprising azd2171 and imatinib

Publications (1)

Publication Number Publication Date
NO20071426L true NO20071426L (no) 2007-06-18

Family

ID=35355143

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071426A NO20071426L (no) 2004-09-27 2007-03-16 Kreft kombinasjonsbehandling omfattende AZD2171 og Imatinib

Country Status (11)

Country Link
US (2) US20080015205A1 (no)
EP (1) EP1796672A1 (no)
JP (1) JP2008514576A (no)
KR (1) KR20070073813A (no)
AU (1) AU2005288736B2 (no)
BR (1) BRPI0516024A (no)
CA (1) CA2579067A1 (no)
IL (1) IL181608A0 (no)
MX (1) MX2007003506A (no)
NO (1) NO20071426L (no)
WO (1) WO2006035203A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0008269D0 (en) * 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
GB0310401D0 (en) * 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
BRPI0508959A (pt) * 2004-03-23 2007-08-14 Astrazeneca Ab uso de azd2171 ou de um sal do mesmo farmaceuticamente aceitável, uso de sal maleato de azd2171 e oxaliplatina, composição farmacêutica, kit, e, método para a produção de um efeito antiangiogênico e/ou de redução da permeabilidade vascular em um animal de sangue quente
GB0406446D0 (en) * 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
GB0406445D0 (en) * 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
KR20070072543A (ko) * 2004-09-27 2007-07-04 아스트라제네카 아베 Ｚｄ6474 및 이마티닙을 포함하는 병합법
EP1901754A2 (en) * 2005-07-06 2008-03-26 AstraZeneca AB Combination therapy of cancer with azd2171 and gemcitabine
KR20080077678A (ko) * 2005-12-22 2008-08-25 아스트라제네카 아베 Ａｚｄ2171 및 페메트렉시드의 조합물
MX2013011199A (es) * 2011-04-01 2013-12-16 Threshold Pharmaceuticals Inc Metodos para tratar el cancer.
KR101386697B1 (ko) 2012-06-18 2014-04-18 아주대학교산학협력단 이매티닙 또는 이의 약학적으로 허용되는 염을 유효성분으로 포함하는 혈관 투과성 관련 질환의 치료 또는 예방용 조성물
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US9353123B2 (en) * 2013-02-20 2016-05-31 Kala Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
CA3280124A1 (en) 2013-07-31 2025-10-31 Avalyn Pharma Inc. Aerosol imatinib compounds and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
KR20160099084A (ko) 2013-11-01 2016-08-19 칼라 파마슈티컬스, 인크. 치료 화합물의 결정질 형태 및 그의 용도
US10071109B2 (en) 2013-11-06 2018-09-11 Molecular Templates, Inc. Predictive biomarker for hypoxia-activated prodrug therapy
WO2017142871A1 (en) * 2016-02-15 2017-08-24 Astrazeneca Ab Methods comprising fixed intermittent dosing of cediranib
WO2018048750A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
US10253036B2 (en) 2016-09-08 2019-04-09 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
EP3509421A4 (en) 2016-09-08 2020-05-20 Kala Pharmaceuticals, Inc. CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE05345B1 (et) * 1999-02-10 2010-10-15 Astrazeneca Ab Kinasoliini derivaadid angiogeneesi inhibiitoritena
JP2004043390A (ja) * 2002-07-12 2004-02-12 Nagoya Industrial Science Research Inst 抗腫瘍剤
DK2316831T3 (da) * 2002-11-21 2013-06-10 Novartis Ag 2-(Morpholin-4-yl)pyrimidiner som phosphotidylinositol (PI)-3-kinaseinhibitorer samt deres anvendelse ved behandling af cancer
GB2398565A (en) * 2003-02-18 2004-08-25 Cipla Ltd Imatinib preparation and salts
EA200600495A1 (ru) * 2003-09-23 2006-10-27 Новартис Аг Комбинация ингибитора vegf рецептора с химиотерапевтическим агентом

Also Published As

Publication number Publication date
EP1796672A1 (en) 2007-06-20
MX2007003506A (es) 2007-05-10
BRPI0516024A (pt) 2008-08-19
AU2005288736A1 (en) 2006-04-06
US20080015205A1 (en) 2008-01-17
IL181608A0 (en) 2007-07-04
CA2579067A1 (en) 2006-04-06
KR20070073813A (ko) 2007-07-10
WO2006035203A1 (en) 2006-04-06
JP2008514576A (ja) 2008-05-08
AU2005288736B2 (en) 2008-08-14
US20090325977A1 (en) 2009-12-31

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