NO20071821L - Fremgangsmate for belegging av pulver - Google Patents

Fremgangsmate for belegging av pulver

Info

Publication number
NO20071821L
NO20071821L NO20071821A NO20071821A NO20071821L NO 20071821 L NO20071821 L NO 20071821L NO 20071821 A NO20071821 A NO 20071821A NO 20071821 A NO20071821 A NO 20071821A NO 20071821 L NO20071821 L NO 20071821L
Authority
NO
Norway
Prior art keywords
active substance
supercritical
particles
coating agent
moving
Prior art date
Application number
NO20071821A
Other languages
English (en)
Other versions
NO341130B1 (no
Inventor
Marilyn Alderone
Elisabeth Rodier
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of NO20071821L publication Critical patent/NO20071821L/no
Publication of NO341130B1 publication Critical patent/NO341130B1/no

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/003—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A23P10/35—Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Birds (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Oppfinnelsen gjelder en fremgangsmåte for belegging av pulverformige faste aktive substanser som er kjennetegnet ved at den omfatter de følgende trinn: a) tilveiebringe (2, 3,4) en blanding som omfatter minst et beleggingsmiddel hvori det er oppløst et superkritisk eller subkritisk fluid ved betingelser av temperatur og trykk som lar det gitte fluidet bli ved superkritiske eller subkritiske betingelser; b) tilveiebringe (7) individuelle bevegelige partikler av minst en pulverformig fast aktiv substans; e) kontakte (8) blandingen og de bevegelige individualiserte partiklene av den aktive substansen ved betingelser av temperatur og trykk som sikrer den samtidige ekspansjonen av det superkritiske eller subkritiske fluidet og dens tilbakeføring til gasstilstand, atomiseringen av beleggingsmiddelet og dens solidifisering rundt de bevegelige individualiserte partiklene av den aktive substansen; d) separere og restituere de belagde partiklene (9). Oppfinnelsen gjelder også belagde mikropartikler av aktiv substans, der hver mikropartikkel omfatter suksessivt en kjerne som inneholder den aktive substansen og et skjell som inneholder beleggingsmiddelet kjennetegnet ved at de er oppnådd ved den. foreliggende oppfinnelsen og ved at den aktive substansen er fast og varmefølsom ved romtemperatur og ved at gjennomsnittsstørrelsen av kjernen av den aktive substansen er mindre enn 50 \ xm.
NO20071821A 2004-09-09 2007-04-10 Prosess for belegning av pulveriserte faste aktive substanser, mikropartikler fremstilt ved nevnte prosess og bruk av disse i formuleringer. NO341130B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0409563A FR2874836B1 (fr) 2004-09-09 2004-09-09 Procede d'enrobage de poudres
PCT/FR2005/002236 WO2006030112A1 (fr) 2004-09-09 2005-09-08 Procede d'enrobage de poudres

Publications (2)

Publication Number Publication Date
NO20071821L true NO20071821L (no) 2007-06-08
NO341130B1 NO341130B1 (no) 2017-08-28

Family

ID=34949152

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071821A NO341130B1 (no) 2004-09-09 2007-04-10 Prosess for belegning av pulveriserte faste aktive substanser, mikropartikler fremstilt ved nevnte prosess og bruk av disse i formuleringer.

Country Status (19)

Country Link
US (2) US20080102275A1 (no)
EP (1) EP1807187B1 (no)
JP (1) JP5358948B2 (no)
KR (1) KR101248347B1 (no)
CN (1) CN100571856C (no)
AR (1) AR054311A1 (no)
AU (1) AU2005284088B2 (no)
BR (1) BRPI0515027A (no)
CA (1) CA2579581C (no)
ES (1) ES2737839T3 (no)
FR (1) FR2874836B1 (no)
IL (1) IL181623A (no)
MX (1) MX2007002835A (no)
NO (1) NO341130B1 (no)
NZ (1) NZ553531A (no)
RU (1) RU2395331C2 (no)
TW (1) TWI376263B (no)
WO (1) WO2006030112A1 (no)
ZA (1) ZA200702883B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2900845B1 (fr) * 2006-05-15 2009-03-06 Commissariat Energie Atomique Procede et dispositif de synthese de particules organiques ou inorganiques enrobees
JP4997449B2 (ja) * 2007-01-31 2012-08-08 株式会社ファンケル 超臨界流体を用いた油脂コーティング複合化粒子の製法及び複合化粒子
KR101027071B1 (ko) * 2008-08-28 2011-04-11 한국과학기술원 에멀젼 화염 분무 열분해법을 이용한 세라믹 입자의 코팅 방법
FR2941225B1 (fr) * 2009-01-19 2012-08-31 Otv Sa Dispositif d'enrobage avec un materiau polymere floculant a l'etat liquide de grains de ballast utilises pour le traitement de l'eau par floculation lestee, et installation correspondante.
KR101102834B1 (ko) * 2010-02-24 2012-01-05 충남대학교산학협력단 신규한 리포좀 제조 방법 및 장치
IT1398648B1 (it) * 2010-03-09 2013-03-08 Probiotical Spa Prodotto alimentare comprendente batteri probiotici rivestiti con un rivestimento di origine vegetale.
DE102011085685A1 (de) * 2011-11-03 2013-05-08 Beiersdorf Ag Kosmetische Zubereitung mit pulverisierten Stoffen zur Verbesserung der Parfümhaftung
DE102011085688A1 (de) * 2011-11-03 2013-05-08 Beiersdorf Ag Kosmetische Zubereitungen mit pulverisierten hydrophoben Stoffen
DE102011085694A1 (de) * 2011-11-03 2013-05-08 Beiersdorf Ag Kosmetische Zubereitung mit pulverisierten hydrophilen Stoffen
WO2014052973A1 (en) * 2012-09-28 2014-04-03 Stelo Technologies Methods of making silver nanoparticles and their applications
CN108559236B (zh) * 2018-03-21 2020-11-17 奚桢浩 一种具有微纳结构的组织工程支架材料及其制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3924953A (en) * 1974-12-18 1975-12-09 Us Navy Helix pitch monitor
JPS6186606A (ja) * 1984-10-05 1986-05-02 Hitachi Ltd 非接触形状測定方法
US4983043A (en) * 1987-04-17 1991-01-08 Industrial Technology Institute High accuracy structured light profiler
DE3744329A1 (de) * 1987-12-28 1989-07-06 Schwarz Pharma Gmbh Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung
US4969746A (en) * 1988-09-02 1990-11-13 R. J. Reynolds Tobacco Company Component inspection apparatus and method
DE3831401A1 (de) * 1988-09-15 1990-03-29 Kolb Gmbh & Co Hans Verfahren und vorrichtung zur automatisierten beruehrungsfreien oberflaechenkontrolle von zylindrischen teilen
EP0388923B1 (en) * 1989-03-22 1993-07-21 Union Carbide Chemicals And Plastics Company, Inc. Precursor coating compositions
EP0388915B1 (en) * 1989-03-22 1993-10-06 Union Carbide Chemicals And Plastics Company, Inc. Precursor coating compositions
US5164995A (en) * 1989-11-27 1992-11-17 General Motors Corporation Signature analysis apparatus
US5171613A (en) * 1990-09-21 1992-12-15 Union Carbide Chemicals & Plastics Technology Corporation Apparatus and methods for application of coatings with supercritical fluids as diluents by spraying from an orifice
US5291272A (en) * 1991-09-27 1994-03-01 Criterion Resources, Inc. Method and apparatus for measuring dimensional variables of threaded pipe
SI9400079B (sl) * 1994-02-15 2003-02-28 Dr. Weidner Eckhard, Dipl. Ing. Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom
US6055329A (en) * 1994-06-09 2000-04-25 Sherikon, Inc. High speed opto-electronic gage and method for gaging
US5646724A (en) * 1995-08-18 1997-07-08 Candid Logic, Inc. Threaded parts inspection device
US5833891A (en) * 1996-10-09 1998-11-10 The University Of Kansas Methods for a particle precipitation and coating using near-critical and supercritical antisolvents
FR2753639B1 (fr) * 1996-09-25 1998-12-11 Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede
US5766637A (en) * 1996-10-08 1998-06-16 University Of Delaware Microencapsulation process using supercritical fluids
CN1233169A (zh) * 1996-10-14 1999-10-27 弗·哈夫曼-拉罗切有限公司 一种粉末状制剂的制备工艺
GB9800936D0 (en) * 1997-05-10 1998-03-11 Univ Nottingham Biofunctional polymers
EP0991455B1 (en) * 1997-06-20 2004-11-24 SmithKline Beecham plc Treatment of a substance with a dense fluid (e.g. with a supercritical fluid)
ATE204787T1 (de) * 1997-10-06 2001-09-15 Adalbert Raps Stiftung Verfahren zur herstellung eines pulverförmigen produktes aus einem flüssigen stoff oder stoffgemisch
CA2306215C (en) * 1997-10-15 2010-06-22 University Of South Florida Supercritical fluid aided coating of particulate material
US6083565A (en) * 1998-11-06 2000-07-04 North Carolina State University Method for meniscus coating with liquid carbon dioxide
FR2791580B1 (fr) * 1999-04-02 2001-05-04 Centre Nat Rech Scient Procede pour l'enrobage de particules
JP4309531B2 (ja) * 1999-11-02 2009-08-05 大川原化工機株式会社 微粒子のコーティング方法及び装置
FR2809309B1 (fr) * 2000-05-23 2004-06-11 Mainelab Microspheres a liberation prolongee pour administration injectable
FR2811913B1 (fr) * 2000-07-19 2003-09-19 Separex Sa Procede d'encapsulation sous forme de micro-capsules de fines particules solides
US7128794B2 (en) * 2001-10-30 2006-10-31 Michelin Recherche Et Technique S.A. Method for retreading a tire
WO2003049701A2 (en) * 2001-12-10 2003-06-19 Spherics, Inc. Methods and products useful in the formation and isolation of microparticles
DE10233864A1 (de) * 2002-01-03 2003-07-17 Messer Griesheim Gmbh Verfahren und Vorrichtung zur Herstellung pulverförmiger Produkte
JP2003200032A (ja) * 2002-01-09 2003-07-15 Oogawara Kakoki Kk 微粒子のコーティング方法及び装置
FR2838356B1 (fr) * 2002-04-15 2004-05-28 Separex Sa Procede d'obtention d'une suspension stable de particules dans un liquide

Also Published As

Publication number Publication date
FR2874836A1 (fr) 2006-03-10
BRPI0515027A (pt) 2008-07-01
RU2007112919A (ru) 2008-10-27
NZ553531A (en) 2011-01-28
CN101035610A (zh) 2007-09-12
AR054311A1 (es) 2007-06-20
AU2005284088A1 (en) 2006-03-23
TWI376263B (en) 2012-11-11
JP5358948B2 (ja) 2013-12-04
WO2006030112A1 (fr) 2006-03-23
FR2874836B1 (fr) 2007-04-27
US20120189679A1 (en) 2012-07-26
AU2005284088B2 (en) 2010-06-03
NO341130B1 (no) 2017-08-28
US20080102275A1 (en) 2008-05-01
KR20070097019A (ko) 2007-10-02
EP1807187B1 (fr) 2019-05-08
IL181623A0 (en) 2007-07-04
IL181623A (en) 2014-05-28
CN100571856C (zh) 2009-12-23
CA2579581A1 (fr) 2006-03-23
TW200609036A (en) 2006-03-16
CA2579581C (fr) 2012-12-04
ES2737839T3 (es) 2020-01-16
EP1807187A1 (fr) 2007-07-18
ZA200702883B (en) 2008-08-27
JP2008512233A (ja) 2008-04-24
RU2395331C2 (ru) 2010-07-27
KR101248347B1 (ko) 2013-04-02
MX2007002835A (es) 2007-04-30

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