NO20071826L - 1,5-diheterosykel-1H-triazolderivat - Google Patents
1,5-diheterosykel-1H-triazolderivatInfo
- Publication number
- NO20071826L NO20071826L NO20071826A NO20071826A NO20071826L NO 20071826 L NO20071826 L NO 20071826L NO 20071826 A NO20071826 A NO 20071826A NO 20071826 A NO20071826 A NO 20071826A NO 20071826 L NO20071826 L NO 20071826L
- Authority
- NO
- Norway
- Prior art keywords
- diheterosykel
- triazole
- salt
- cox
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102100038277 Prostaglandin G/H synthase 1 Human genes 0.000 abstract 1
- 108050003243 Prostaglandin G/H synthase 1 Proteins 0.000 abstract 1
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 abstract 1
- 108050003267 Prostaglandin G/H synthase 2 Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Det beskrives en forbindelse representert ved Formel (I): hvor Ar1, Ar2, R1 og R2 hver representerer en substituent, et salt derav, eller et solvat av forbindelsen eller saltet og til en medisin inneholdende samme. Ifølge foreliggende oppfinnelse er det tilveiebrakt et kraftig blodplateaggregeringsundertrykkende middel som ikke hemmer COX-1 og COX-2.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004303851 | 2004-10-19 | ||
| PCT/JP2005/019207 WO2006043594A1 (ja) | 2004-10-19 | 2005-10-19 | 1,5-ジ複素環-1h-トリアゾール誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20071826L true NO20071826L (no) | 2007-06-14 |
Family
ID=36203009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071826A NO20071826L (no) | 2004-10-19 | 2007-04-10 | 1,5-diheterosykel-1H-triazolderivat |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080125409A1 (no) |
| EP (1) | EP1803719A4 (no) |
| JP (1) | JPWO2006043594A1 (no) |
| KR (1) | KR20070063530A (no) |
| CN (1) | CN101039934A (no) |
| AU (1) | AU2005296582A1 (no) |
| CA (1) | CA2583153A1 (no) |
| IL (1) | IL182538A0 (no) |
| MX (1) | MX2007004643A (no) |
| NO (1) | NO20071826L (no) |
| RU (1) | RU2007118659A (no) |
| WO (1) | WO2006043594A1 (no) |
| ZA (1) | ZA200703562B (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060005378A (ko) * | 2003-04-21 | 2006-01-17 | 다이이찌 세이야꾸 가부시기가이샤 | 5원 복소환 유도체 |
| MX387055B (es) | 2014-06-06 | 2025-03-19 | Res Triangle Inst | Agonistas del receptor de apelina (apj) y usos de los mismos. |
| WO2017100558A1 (en) | 2015-12-09 | 2017-06-15 | Research Triangle Institute | Improved apelin receptor (apj) agonists and uses thereof |
| MX394907B (es) * | 2016-10-12 | 2025-03-24 | Res Triangle Inst | Agonistas heterociclicos del receptor de apelina (apj) y usos de los mismos |
| HUE063556T2 (hu) | 2019-11-26 | 2024-01-28 | Bayer Ag | [(1,5-difenil-1H-1,2,4-triazol-3-il)oxi]ecetsav-származékok és ezek sói, ezeket tartalmazó növényvédõszer haszon- vagy kultúrnövényekhez, eljárás ezek elõállítására és alkalmazásuk széfenerként |
| US12606542B2 (en) | 2020-11-05 | 2026-04-21 | Bayer Aktiengesellschaft | [(1,5-diheteroaryl-1H-1,2,4-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants |
| WO2025250430A1 (en) * | 2024-05-25 | 2025-12-04 | Bio-Rad Laboratories, Inc. | Mixed mode charge induction ion exchange (iex) chromatography (mmciic) ligands and methods of use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR878201A0 (en) * | 2001-11-09 | 2001-12-06 | Fujisawa Pharmaceutical Co., Ltd. | New compounds |
| WO2004060367A1 (en) * | 2002-12-30 | 2004-07-22 | Fujisawa Pharmaceutical Co., Ltd. | Imidazole and triazole derivatives useful as selective cox-1 inhibitors |
| US7622471B2 (en) * | 2003-02-07 | 2009-11-24 | Daiichi Pharmaceutical Co., Ltd. | Pyrazole derivatives having a pyridazine and pyridine functionality |
| KR20060005378A (ko) * | 2003-04-21 | 2006-01-17 | 다이이찌 세이야꾸 가부시기가이샤 | 5원 복소환 유도체 |
-
2005
- 2005-10-19 ZA ZA200703562A patent/ZA200703562B/xx unknown
- 2005-10-19 RU RU2007118659/04A patent/RU2007118659A/ru not_active Application Discontinuation
- 2005-10-19 WO PCT/JP2005/019207 patent/WO2006043594A1/ja not_active Ceased
- 2005-10-19 KR KR1020077008162A patent/KR20070063530A/ko not_active Withdrawn
- 2005-10-19 US US11/577,476 patent/US20080125409A1/en not_active Abandoned
- 2005-10-19 AU AU2005296582A patent/AU2005296582A1/en not_active Abandoned
- 2005-10-19 CA CA002583153A patent/CA2583153A1/en not_active Abandoned
- 2005-10-19 EP EP05795875A patent/EP1803719A4/en not_active Withdrawn
- 2005-10-19 MX MX2007004643A patent/MX2007004643A/es unknown
- 2005-10-19 JP JP2006543037A patent/JPWO2006043594A1/ja active Pending
- 2005-10-19 CN CNA2005800352283A patent/CN101039934A/zh active Pending
-
2007
- 2007-04-10 NO NO20071826A patent/NO20071826L/no not_active Application Discontinuation
- 2007-04-12 IL IL182538A patent/IL182538A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070063530A (ko) | 2007-06-19 |
| AU2005296582A1 (en) | 2006-04-27 |
| JPWO2006043594A1 (ja) | 2008-05-22 |
| EP1803719A4 (en) | 2008-07-02 |
| CN101039934A (zh) | 2007-09-19 |
| CA2583153A1 (en) | 2006-04-27 |
| RU2007118659A (ru) | 2008-11-27 |
| IL182538A0 (en) | 2007-09-20 |
| MX2007004643A (es) | 2007-06-08 |
| ZA200703562B (en) | 2008-08-27 |
| EP1803719A1 (en) | 2007-07-04 |
| US20080125409A1 (en) | 2008-05-29 |
| WO2006043594A1 (ja) | 2006-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |