NO20072931L - Forbedret doseringsregime av temozolomid for behandling av kreft basert pa pasientens MGMT-niva - Google Patents

Forbedret doseringsregime av temozolomid for behandling av kreft basert pa pasientens MGMT-niva

Info

Publication number
NO20072931L
NO20072931L NO20072931A NO20072931A NO20072931L NO 20072931 L NO20072931 L NO 20072931L NO 20072931 A NO20072931 A NO 20072931A NO 20072931 A NO20072931 A NO 20072931A NO 20072931 L NO20072931 L NO 20072931L
Authority
NO
Norway
Prior art keywords
treatment
temozolomide
patient
dosing regimen
cancer based
Prior art date
Application number
NO20072931A
Other languages
English (en)
Inventor
Chen Zong
Benjamin Winograd
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36168622&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20072931(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO20072931L publication Critical patent/NO20072931L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/91005—Transferases (2.) transferring one-carbon groups (2.1)
    • G01N2333/91011—Methyltransferases (general) (2.1.1.)
    • G01N2333/91017—Methyltransferases (general) (2.1.1.) with definite EC number (2.1.1.-)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Det er beskrevet anvendelse av temozolomid til fremstilling av et medikament for behandling av kreft hos en pasient som trenger slik behandling, som omfatter administrering av temozolomid i henhold til forbedrede doseringsregimer og/eller -planer basert på pasientens MGMT-nivå. Det er også beskrevet ytterligere forbedrede doseringsregimer og/eller -planer for behandling av pasienter med temozolomid.
NO20072931A 2004-11-09 2007-06-08 Forbedret doseringsregime av temozolomid for behandling av kreft basert pa pasientens MGMT-niva NO20072931L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62625804P 2004-11-09 2004-11-09
PCT/US2005/040449 WO2006052976A2 (en) 2004-11-09 2005-11-07 Improved dosing regimen of temozolomide for treating cancer based on the patient’s mgmt level

Publications (1)

Publication Number Publication Date
NO20072931L true NO20072931L (no) 2007-08-03

Family

ID=36168622

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072931A NO20072931L (no) 2004-11-09 2007-06-08 Forbedret doseringsregime av temozolomid for behandling av kreft basert pa pasientens MGMT-niva

Country Status (13)

Country Link
US (2) US20060100188A1 (no)
EP (1) EP1830845A2 (no)
JP (2) JP2008519584A (no)
CN (1) CN101098696A (no)
AU (1) AU2005304672B2 (no)
BR (1) BRPI0517976A (no)
CA (1) CA2585446A1 (no)
MX (1) MX2007005581A (no)
NO (1) NO20072931L (no)
NZ (1) NZ554831A (no)
TW (1) TW200630089A (no)
WO (1) WO2006052976A2 (no)
ZA (1) ZA200703716B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100346784C (zh) * 2002-02-22 2007-11-07 先灵公司 抗肿瘤剂,特别是替莫唑胺的药物制剂,其制备方法和用途
US20060100188A1 (en) * 2004-11-09 2006-05-11 Chen Zong Treatment methods
US20070111979A1 (en) * 2005-11-07 2007-05-17 Walter Robert Bishop Methods of treating cell proliferative disorders using a compressed temozolomide dosing schedule
SI2338487T1 (sl) * 2006-01-17 2014-01-31 Abbott Laboratories Kombinacijska terapija z inhibitorji PARP
CA2648640C (en) 2006-04-05 2016-02-16 Schering Corporation Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
TWI363058B (en) 2006-04-05 2012-05-01 Opko Health Inc Hydrochloride salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and preparation process therefor
WO2007133496A2 (en) * 2006-05-09 2007-11-22 Schering Corporation Development of a novel assay for mgmt (methyl guanine transferase)
AR061618A1 (es) * 2006-06-26 2008-09-10 Schering Corp Formas de dosificacion unitaria de temozolomida
CA2686848A1 (en) * 2007-05-08 2008-11-20 Schering Corporation Methods of treatment using intravenous formulations comprising temozolomide
US20080319039A1 (en) * 2007-06-25 2008-12-25 Jacqueline Rose Bersch Unit dosage forms of temozolomide
US8435972B2 (en) * 2010-09-02 2013-05-07 Emory University Method for the treatment of central nervous system cancers and compositions related thereto
WO2014172425A1 (en) * 2013-04-17 2014-10-23 Signal Pharmaceuticals, Llc Treatment of cancer with dihydropyrazino-pyrazines
JP6957035B2 (ja) 2015-04-10 2021-11-02 トーマス・ジェファーソン・ユニバーシティ 対象への移植用の免疫原性拡散チャンバおよびその調製方法
CN110408694A (zh) * 2018-04-26 2019-11-05 胤安国际（辽宁）基因科技股份有限公司 评估替莫唑胺在治疗脑胶质瘤患者的敏感性的新方法
US20220195440A1 (en) * 2019-03-28 2022-06-23 Thomas Jefferson University Methods for treating cancers using antisense
WO2023113538A1 (ko) * 2021-12-17 2023-06-22 숙명여자대학교산학협력단 뇌종양 치료를 위한 글리세오플빈 병용요법
CN119318654A (zh) * 2024-12-16 2025-01-17 中国医学科学院基础医学研究所 氟达拉滨和替莫唑胺联用在治疗脑胶质瘤中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
US5876146A (en) * 1995-10-27 1999-03-02 General Electric Company Apparatus and methods for repairing jet pump diffusers in a nuclear reactor
US5786146A (en) * 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6017704A (en) * 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5939098A (en) * 1996-09-19 1999-08-17 Schering Corporation Cancer treatment with temozolomide
CN102160864A (zh) * 1999-03-30 2011-08-24 先灵公司 用替莫唑胺改善癌症治疗
US6346524B1 (en) * 1999-03-30 2002-02-12 Schering Corporation Cancer treatment with temozolomide
WO2001085221A2 (en) * 2000-05-12 2001-11-15 Duke University Assessing levels of o6-alkylguanine-dna alkyltransferase in vivo
EP1328656A4 (en) * 2000-09-29 2005-09-14 Univ Johns Hopkins Med METHOD OF PREDICTING CLINICAL REACTION TO CHEMOTHERAPEUTIC TREATMENT WITH ALKYLATING AGENTS
EP1332208A2 (en) * 2000-10-30 2003-08-06 Gene Logic, Inc. Partially double-stranded nucleic acids, methods of making, and use thereof
DE60144246D1 (de) * 2000-11-20 2011-04-28 Takeda Pharmaceutical Imidazolderivate, verfahren zu deren herstellung und deren verwendung
AU2003276087A1 (en) * 2002-10-28 2004-05-13 Pharmacia Italia Spa Method for optimizing therapeutic efficacy of nemorubicin
US7718364B2 (en) * 2003-03-25 2010-05-18 John Wayne Cancer Institute DNA markers for management of cancer
US20060100188A1 (en) * 2004-11-09 2006-05-11 Chen Zong Treatment methods
US20070111979A1 (en) * 2005-11-07 2007-05-17 Walter Robert Bishop Methods of treating cell proliferative disorders using a compressed temozolomide dosing schedule

Also Published As

Publication number Publication date
CN101098696A (zh) 2008-01-02
BRPI0517976A (pt) 2008-10-21
JP2008519584A (ja) 2008-06-12
JP2011121960A (ja) 2011-06-23
CA2585446A1 (en) 2006-05-18
MX2007005581A (es) 2007-05-23
AU2005304672A1 (en) 2006-05-18
WO2006052976A2 (en) 2006-05-18
ZA200703716B (en) 2008-09-25
TW200630089A (en) 2006-09-01
AU2005304672B2 (en) 2010-03-11
NZ554831A (en) 2009-10-30
WO2006052976A3 (en) 2006-08-17
EP1830845A2 (en) 2007-09-12
US20090247598A1 (en) 2009-10-01
US20060100188A1 (en) 2006-05-11

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